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Cancer: Brain Cancers
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Total 538 results found since Jan 2013.
The combination of baicalin with knockdown of miR148a gene suppresses cell viability and proliferation and induces the apoptosis and autophagy of human glioblastoma multiforme T98G and U87MG cells
CONCLUSION: The siRNA-induced miR148a mRNA knockdown in combination with baicalin may offer a novel therapeutic strategy to more effective control the growth of human GBM cells. Thus, knockdown of this gene in combination with baicalin inhibits proliferation (cell cycle arrest in S phase in T98G but not in U87MG cells), induces apoptosis and regulates autophagy in T98G and U87MG cells, but further studies urgently needed to confirm a positive phenomenon for the treatment of GBM.PMID:35761505 | DOI:10.2174/1389201023666220627144100
Source: Current Pharmaceutical Biotechnology - June 28, 2022 Category: Biotechnology Authors: Monika Paul-Samojedny Emilia Liduk Ma łgorzata Kowalczyk Paulina Borkowska Aleksandra Zieli ńska Renata Suchanek-Raif Jan Kowalski Source Type: research
Interference of P2X4 receptor expression in tumor-associated macrophages suppresses migration and invasion of glioma cells
CONCLUSION: Interference of P2X4 receptor in the TAMs suppresses the migration and invasion of glioma cells possibly by lowering the expressions of IL-1β and IL-18.PMID:35673908 | DOI:10.12122/j.issn.1673-4254.2022.05.05
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: X Yang H Shen Q Li Z Dai R Yang G Huang R Chen F Wang J Song H Hua Source Type: research
