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Nutrition: Vitamins

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Total 92 results found since Jan 2013.

High Prevalence of Hypovitaminosis D in Patients Presenting with Proximal Muscle Weakness: A Sub-Himalayan Study.
Conclusion: Muscle weakness is common among vitamin-D deficient individuals. Our study indicates that more focus should be on muscle symptoms in at risk population groups. The vitamin D deficiency related myopathy should not be missed due to its potential reversibility with vitamin D supplementation. PMID: 29322711 [PubMed - in process]
Source: Journal of the Association of Physicians of India - January 14, 2018 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Myopathy: Effect of Vitamin D Deficiency Beyond Bones.
We report the case of a middle aged female with chronic quadriparesis and new onset anemia associated with Vitamin D deficiency. Patient responded to vitamin D supplementation alone. PMID: 29319256 [PubMed - in process]
Source: Journal of the Association of Physicians of India - January 11, 2018 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Update on recent progress in vitamin D research. Eldecalcitol(R) and fall prevention - Suzuki T.
In the elderly, vitamin D deficiency results not only in impaired bone mineralization, but also myopathy. Low vitamin D has also been shown to be associated with decline of muscle strength, sarcopenia, functional limitation, and disability. Several recent ...
Source: SafetyLit - October 30, 2017 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Common therapeutic approaches of sarcopenia in the elderly and uremic myopathy.
Abstract The gradual loss of weight and function of muscle in patients with chronic kidney disease as in the elderly impacts the quality of life. Early management should help slow the functional limitation. Physical activity is the first therapy to propose that ensures stability of muscle mass and improved function. Resistance training programs have proven effective but are not yet widely available in nephrology units. The nutritional management should not be forgotten because there is a resistance to anabolism and protein intake should be involved in physical activity program. Associated treatments should not be ...
Source: Nephrologie and Therapeutique - June 9, 2017 Category: Urology & Nephrology Authors: Chauveau P, Moreau K, Lasseur C, Combe C, Aparicio M Tags: Nephrol Ther Source Type: research

The establishment of tocopherol reference intervals for Hungarian adult population using validated HPLC method.
Abstract Evidence suggests that decreased α-tocopherol (the most biologically active substance in the vitamin E group) level can cause neurological symptoms, most likely ataxia. The aim of the current study was to first provide reference intervals for serum tocopherols in the adult Hungarian population with appropriate sample size recruiting healthy control subjects and neurological patients suffering from conditions without symptoms of ataxia, myopathy or cognitive deficiency. A validated HPLC method applying a diode array detector and rac-tocol as internal standard was utilized for that purpose. Furthermore, se...
Source: Biomedical Chromatography : BMC - February 8, 2017 Category: Biomedical Science Authors: Veres G, Szpisjak L, Bajtai A, Siska A, Klivényi P, Ilisz I, Földesi I, Vécsei L, Zádori D Tags: Biomed Chromatogr Source Type: research

Potential role for the VDR agonist elocalcitol in metabolic control: Evidences in human skeletal muscle cells
Publication date: March 2017 Source:The Journal of Steroid Biochemistry and Molecular Biology, Volume 167 Author(s): Cristina Antinozzi, Clarissa Corinaldesi, Carla Giordano, Annalinda Pisano, Bruna Cerbelli, Silvia Migliaccio, Luigi Di Luigi, Katia Stefanantoni, Gabriella Barbara Vannelli, Salvatore Minisola, Guido Valesini, Valeria Riccieri, Andrea Lenzi, Clara Crescioli Vitamin D plays a pivotal role to maintain skeletal muscle integrity and health. Vitamin D deficiency characterizes inflammatory myopathy (IM) and diabetes, often overlapping diseases involving skeletal muscle damage. Vitamin D receptor (VDR) agonists l...
Source: The Journal of Steroid Biochemistry and Molecular Biology - February 2, 2017 Category: Biochemistry Source Type: research

Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - December 15, 2016 Category: Biochemistry Authors: Avisek Majumder, JyotirmayaBehera, Navena Jeremic, Suresh C Tyagi Tags: Article Source Type: research

Impact of Vitamin D Status on Statin-Induced Myopathy
Conclusion Vitamin D status may be considered a modifiable risk factor for muscle-related adverse effects of statins, and supplementation of vitamin D (particularly when ⩽20 ng/mL) may improve statin tolerance.
Source: Journal of Clinical and Translational Endocrinology - November 23, 2016 Category: Endocrinology Source Type: research

Equine atypical myopathy: a metabolic study
Publication date: Available online 29 July 2016 Source:The Veterinary Journal Author(s): R. Karlíková, J. Široká, P. Jahn, D. Friedecký, A. Gardlo, H. Janečková, F. Hrdinová, Z. Drábková, T. Adam Atypical myopathy is a potentially fatal disease of grazing horses. It is reportedly caused by the ingestion of sycamore seeds containing toxic hypoglycin A. In order to study metabolic changes, serum and urine samples from nine horses with atypical myopathy and 12 control samples from clinically healthy horses were collected and then analysed using a high-performance liquid chromatography coupled with tandem ...
Source: The Veterinary Journal - July 29, 2016 Category: Veterinary Research Source Type: research

Effect of Preoperative Vitamin D Levels on Functional Performance after Total Knee Arthroplasty.
CONCLUSIONS: We concluded that vitamin D deficiency has a negative effect on function in knee osteoarthritic patients. However, postoperative vitamin D supplementation can lead to functional recovery in these patients. Thus, TKA should not be delayed in vitamin D deficient patients; rather supplementation in the postoperative period is preferable to achieve comparable functional outcome at 3 months to patients with vitamin D sufficiency. PMID: 27247739 [PubMed - in process]
Source: Clinics in Orthopedic Surgery - June 2, 2016 Category: Orthopaedics Tags: Clin Orthop Surg Source Type: research

Correlation of Vitamin D and Body Mass Index with Modic Changes in Patients with Non-Specific Low Back Pain in a Sub-Tropical Asian Population.
CONCLUSIONS: Vitamin D deficiency and obesity have significant relations with LBP. Low vitamin D levels is associated with Modic changes but whether they represent a subgroup of patients whose low backpain is associated with low vitamin D needs to be further evaluated. PMID: 26949453 [PubMed]
Source: Asian Spine Journal - March 8, 2016 Category: Orthopaedics Tags: Asian Spine J Source Type: research

1{alpha},25(OH)2D3 and Skeletal Muscle Genomics and Proteomics
Muscle weakness and myopathy are observed in vitamin D deficiency and chronic renal failure, where concentrations of the active vitamin D3 metabolite, 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3), are low. To evaluate the mechanism of action of 1α,25(OH)2D3 in skeletal muscle, we examined mitochondrial oxygen consumption, dynamics, and biogenesis and changes in expression of nuclear genes encoding mitochondrial proteins in human skeletal muscle cells following treatment with 1α,25(OH)2D3. The mitochondrial oxygen consumption rate (OCR) increased in 1α,25(OH)2D3-treated cells. Vitamin D3 metabolites lacking a 1α-hydroxyl ...
Source: Journal of Biological Chemistry - January 15, 2016 Category: Chemistry Authors: Ryan, Z. C., Craig, T. A., Folmes, C. D., Wang, X., Lanza, I. R., Schaible, N. S., Salisbury, J. L., Nair, K. S., Terzic, A., Sieck, G. C., Kumar, R. Tags: Gene Regulation Source Type: research

The many faces of melas
We report the case of a 76-year-old man (the second oldest diagnosed case to the authors' knowledge) whose case exemplifies the complexity of diagnosing and managing these patients including the complications of the disease.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: AlMasri, O., Massey, T., Mukhopadhyay, D., Walters, R. J. Tags: Genetics, Epilepsy and seizures, Headache (including migraine), Infection (neurology), Muscle disease, Neuromuscular disease, Musculoskeletal syndromes Thur 21, Parallel session 5: Therapeutics Source Type: research

Autism in the Son of a Woman with Mitochondrial Myopathy and Dysautonomia: A Case Report
Conclusion Given emerging evidence that mitochondrial dysfunction, particularly in the electron transport chain needed for cellular energy production, is an underlying pathophysiological mechanism for some varieties of ASD, clinicians should have a high index of suspicion for mitochondrial disease, especially when they encounter a patient with unusual neurological or constitutional symptoms. The prevalence of mitochondrial disease in ASD patients may be as high as five percent, which means that it is not the “zebra”[27] diagnosis that it might be in a non-ASD patient, where prevalence is about 0.01 percent.10 Reference...
Source: Innovations in Clinical Neuroscience - October 9, 2015 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Asperger's syndrome Autism Behavioral and Cognitive Neurology Case Report Current Issue Intellectual Disability Neurologic Systems and Symptoms Pervasive Developmental Disorders ASD autism spectrum disorder dysauton Source Type: research

Myopathy induced by statin‑ezetimibe combination: Evaluation of potential risk factors
We report a case of myalgia with elevated serum creatinine phosphokinase in a patient after 2 months of therapy with fixed dose combination of atorvastatin and ezetimibe (10 mg each). At the time of the event, patient was undertaking moderate physical exertion in the form of brisk walking for 30–40 min a day and was detected to have low serum Vitamin D levels. The adverse event resolved after stopping atorvastatin-ezetimibe combination therapy. Potential risk factors, such as physical exertion and Vitamin D deficiency, co-existent in dyslipidemic patients, may exacerbate myopathy potential of these drugs, and ...
Source: Indian Journal of Pharmacology - September 15, 2015 Category: Drugs & Pharmacology Authors: Ballari BrahmachariSuparna Chatterjee Source Type: research