This page shows you your search results in order of date.

Order by Relevance | Date

Total 11221 results found since Jan 2013.

Antigen-driven T cell-macrophage interactions mediate the interface between innate and adaptive immunity in histidyl-tRNA synthetase-induced myositis
DiscussionOverall, HRS-induced myositis reflects the complex interplay between multiple cell types that collectively drive a TH1-predominant, pro-inflammatory tissue phenotype requiring antigen-mediated activation of both MyD88- and TCR-dependent T cell signaling pathways.
Source: Frontiers in Immunology - September 22, 2023 Category: Allergy & Immunology Source Type: research

Chapter 3: Evidence for the Use of Early Rhythm Control to Prevent Atrial Fibrillation Progression
This chapter reviews atrial fibrillation (AF) progression and its associated mechanisms, including comorbidities and AF as contributors to atrial myopathy, and atrial myopathy as a contributing factor to AF progression. In addition, the chapter discusses the concept of comorbidities and atrial myopathy as synergistic contributors to adverse outcomes, the notion of “AF begets AF,” and the consequences of AF burden if left untreated. Clinical trials evaluating outcomes with antiarrhythmic drugs (AADs) compared with placebo have demonstrated efficacy, but also reveal a possible proarrhythmic and mortality risk if AAD sele...
Source: The American Journal of Cardiology - September 21, 2023 Category: Cardiology Authors: Thomas F. Deering, James A. Reiffel, Allen J. Solomon, Kamala P. Tamirisa Tags: Video article Source Type: research

The genetic and clinical spectrum in a cohort of 39 families with complex inherited peripheral neuropathies
In conclusion, transthyretin amyloidosis with polyneuropathy (ATTR-PN), GNE myopathy, and neuronal intranuclear inclusion disease (NIID) were the most common genotypes in this cohort of complex IPNs.NOTCH2NLC dynamic mutation testing should be added to the molecular diagnostic workflow. We expanded the genetic and related clinical spectrum of GNE myopathy and ARSACS by reporting novel variants.
Source: Journal of Neurology - September 20, 2023 Category: Neurology Source Type: research

Increased prevalence of mild myopathic changes in the post-COVID-19 duration
CONCLUSIONS: The high prevalence of complaints and objective myopathic findings in our cohort implicated the role of muscle involvement in the post-COVID-19 duration. Considering the socioeconomic and psychological burden of the post-COVID-19 duration among individuals and societies, a better understanding of the symptoms and myopathy is warranted.PMID:37729011 | DOI:10.1080/01616412.2023.2258034
Source: Neurological Research - September 20, 2023 Category: Neurology Authors: Ay şegül Gündüz Merve Hazal Ser Fatma Zehra Çalıkuşu Uygur Tanr ıverdi Hikmet Abbaszade Sena Hakyemez I Lker İnanç Balkan R ıdvan Karaali Fatih Kantarc ı Nurten Uzun Adatepe Source Type: research

Anti-SRP Myopathy with Sensorimotor Polyneuropathy: A Case Report
CONCLUSION: Anti-SRP myopathy can present with sensorimotor polyneuropathy. Thus, the possibility that the same pathological process affected the skeletal muscles and peripheral nerves should be considered.PMID:37723914
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Lei-Ying Huang Yi-Jen Peng Yueh-Feng Sung Source Type: research

Evaluation of safety and efficacy of allogeneic adipose tissue-derived mesenchymal stem cells in pediatric bronchiolitis obliterans syndrome (BoS) after allogeneic hematopoietic stem cell transplantation (allo-HSCT)
CONCLUSIONS: AT-MSCs could be safely administered to our pediatric cases with BoS post-allo-HSCT. Considering their advanced stage of disease, their sub-optimal functional capacity due to steroid-induced complications, and COVID-19 infection post-treatment, we believe that AT-MSC therapy can have possible efficacy in the management of pediatric BoS. The conduction of further studies with larger sample sizes and more frequent injections is prudent for further optimization of AT-MSC therapy against BoS. Trial registration Iranian Registry of Clinical Trials (IRCT), IRCT20201202049568N2. Registered 22 February 2021, https://e...
Source: Cell Research - September 19, 2023 Category: Cytology Authors: Rashin Mohseni Pouya Mahdavi Sharif Maryam Behfar Mohammad Reza Modaresi Rohola Shirzadi Mahta Mardani Leila Jafari Fahimeh Jafari Zeynab Nikfetrat Amir Ali Hamidieh Source Type: research

Rapid and sustained response to JAK inhibition in a child with severe MDA5  + juvenile dermatomyositis
Juvenile dermatomyositis (jDM) is the most common idiopathic inflammatory myopathy of childhood. Amyopathic or hypomyopathic courses have been described.
Source: Pediatric Rheumatology - September 19, 2023 Category: Rheumatology Authors: Timmy Strauss, Claudia G ünther, Anja Schnabel, Christine Wolf, Gabriele Hahn, Min Ae Lee-Kirsch and Normi Brück Tags: Case Report Source Type: research

Myositis after SARS-CoV-2 vaccination occurs more frequently than assumed and is probably causally related
Reumatismo. 2023 Sep 18;75(3). doi: 10.4081/reumatismo.2023.1601.ABSTRACTWe read with interest the article by Camargo-Coronel et al. reporting on a systematic review of patients with idiopathic, inflammatory myopathy developing after anti-SARS-CoV-2 vaccinations.PMID:37721345 | DOI:10.4081/reumatismo.2023.1601
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: J Finsterer A S MohanaSundaram F Scorza Source Type: research

Narrowband Intense Pulsed Light Treatment for Refractory Facial Rash Associated with Dermatomyositis
We present a case of cutaneous dermatomyositis that was successfully treated with narrowband intense pulsed light.PMID:37719932 | PMC:PMC10504899 | DOI:10.2147/CCID.S426762
Source: Clinical, Cosmetic and Investigational Dermatology - September 18, 2023 Category: Dermatology Authors: Yuxin Zheng Suiqing Cai Source Type: research

Cancer-associated regional ischemic myopathy: a rare myopathy
Paraneoplastic myopathies are often inflammatory or necrotizing, and can be associated with specific antibodies.[1] Regional ischemic immune myopathy (RIIM) is a rare disorder attributed to muscle vasculopathy and considered paraneoplastic.[2] Contrary to dermatomyositis, which is associated with complement mediated muscle microangiopathy, capillary depletion, perifascicular pathology and sometimes muscle ischemia,[3] RIIM is characterized by regional necrosis in border zones between damaged perimysial vessels.
Source: Neuromuscular Disorders - September 17, 2023 Category: Neurology Authors: Andre Granger, Pannathat Soontrapa, Christopher J. Klein, Margherita Milone Source Type: research