Autism in the Son of a Woman with Mitochondrial Myopathy and Dysautonomia: A Case Report

Conclusion Given emerging evidence that mitochondrial dysfunction, particularly in the electron transport chain needed for cellular energy production, is an underlying pathophysiological mechanism for some varieties of ASD, clinicians should have a high index of suspicion for mitochondrial disease, especially when they encounter a patient with unusual neurological or constitutional symptoms. The prevalence of mitochondrial disease in ASD patients may be as high as five percent, which means that it is not the “zebra”[27] diagnosis that it might be in a non-ASD patient, where prevalence is about 0.01 percent.10 References 1. American Psychiatric Association. The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Press Inc.; 2001. 2. American Psychiatric Association. The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Washington, DC: American Psychiatric Press Inc.; 2013. 3. Tordjman S, Somogyi E, Coulon N, et al. Gene?×?Environment interactions in autism spectrum disorders: role of epigenetic mechanisms. Front Psychiatry. 2014;5:53. 4. Persico AM, Napolioni V. Autism genetics. Behav Brain Res. 2013;251:95-112. 5. Durdiaková J, Warrier V, Baron-cohen S, Chakrabarti B. Single nucleotide polymorphism rs6716901 in SLC25A12 gene is associated with Asperger syndrome. Mol Autism. 2014;5(1):25. 6. Abbott JA, Francklyn CS, Robey-bond SM. Transfer RNA and human disease. ...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Anxiety Disorders Asperger's syndrome Autism Behavioral and Cognitive Neurology Case Report Current Issue Intellectual Disability Neurologic Systems and Symptoms Pervasive Developmental Disorders ASD autism spectrum disorder dysauton Source Type: research

Related Links:

The study examined social variables and suicidal behaviour tendency among university students in Akwa Ibom State. Two purposes, research questions and hypotheses apiece were formulated to guide the study. The researchers adopted the descriptive survey desi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
This study sets out to explore whether emotional intelligence has a mediating role in the relationship between fear of missing out in social environments (FoMO) and the depression among university students. The study group consisted of 370 (200 female and ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Background and Purpose: Accidents, both intentional and unintentional, are one of the leading causes of death and disability for children around the world and impose a heavy financial burden on the health care system of societies. The aim of the present st...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Road accidents are one of the causes of disability, injury and death. As per the latest road accident data released by the Ministry of Road Transport&Highways (MoRTH), the total number of accidents increased by 2.5 percent from 4,89,400 in 2014 to 5,01,4...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Authors: Zhao HW, Liu H, Liu LY, Liu Z, Dong XS Abstract Paraquat (PQ) as a non-selective heterocyclic herbicide, has been applied worldwide for over a few decades. But PQ is very harmful to humans and rodents. The lung is the main target organ of PQ poisoning. It is an important event that lung epithelial cells are injured during PQ-induced acute lung injury and pulmonary fibrosis. As a regulator of mRNA expression, microRNA (miRNA) may play an important role in the progress. Our study was to investigate the mechanisms of PQ-induced injury of pulmonary epithelial cells through analyzing the profiling of miRNAs and...
Source: Journal of Toxicological Sciences - Category: Toxicology Tags: J Toxicol Sci Source Type: research
CONCLUSION: A significant proportion of patients with LDL-C≥250 mg/dL were not taking lipid-lowering drugs. Similar with many other studies, diagnosis and treatment rates of FH patients were very low in our study. Further national studies are required to increase awareness of the disease in both physicians and patients. PMID: 32744105 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Conclusions: In this cohort, racial/ethnic differences in sleep quality were common. PMID: 32742152 [PubMed - in process]
Source: Ethnicity and Disease - Category: International Medicine & Public Health Tags: Ethn Dis Source Type: research
Publication date: Available online 4 August 2020Source: International Journal of PsychophysiologyAuthor(s): Jayne Morriss, Nico Biagi, Helen Dodd
Source: International Journal of Psychophysiology - Category: Psychiatry & Psychology Source Type: research
This article was first published by the UN Chronicle on 6 July 2020.   Follow @IPSNewsUNBureau !function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],p=/^http:/.test(d.location)?'http':'https';if(!d.getElementById(id)){js=d.createElement(s);;js.src=p+'://';fjs.parentNode.insertBefore(js,fjs);}}(document, 'script', 'twitter-wjs'); The post The UN General Assembly: A 75-Year Journey Towards the Future We Want appeared first on Inter Press Service. Excerpt: Tijjani Muhammad-Bande is President of the 74th Session of the United Nations General Assembly and Permanent Representat...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Development & Aid Gender Global Headlines Health Human Rights Humanitarian Emergencies IPS UN: Inside the Glasshouse Peace TerraViva United Nations UN at 75 Source Type: news
Publication date: September 2020Source: Obstetrics and Gynecology Clinics of North America, Volume 47, Issue 3Author(s): Emily B. Kroska, Zachary N. Stowe
Source: Obstetrics and Gynecology Clinics of North America - Category: OBGYN Source Type: research
More News: Academia | Addison's Disease | ADHD | Adrenal Insufficiency | Anxiety | Arrhythmia | Asperger's Syndrome | Ataxia | Atenolol | Atrial Fibrillation | Audiology | Autism | Brain | Cardiology | Cataracts | Celexa | Child Abuse | Child Development | Children | Cholesterol | Citalopram | Databases & Libraries | Depression | Disability | Electrocardiogram | Emergency Medicine | Environmental Health | Epilepsy | Fluoxetine | Fortamet | Gene Therapy | Genetics | Health | Heart | Hyperactivity | Hypothyroidism | Insurance | Insurers | Laboratory Medicine | Men | Metformin | Mitochondria | Mitochondrial Disease | MRI Scan | Neurology | Neuroscience | Nutrition | Opthalmology | Patent Foramen Ovale | Pathology | Phenytoin | Prozac | Psychiatry | Respiratory Medicine | Rheumatology | Risperdal Consta | Science | Sertraline | Sleep Apnea | Sleep Disorders | Sleep Medicine | Sports Medicine | Statin Therapy | Statistics | Stroke | Study | Substance Abuse | Substance Abuse Disorders | Suicide | Toxicology | Vitamins | Wikis | Zoloft