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Total 92 results found since Jan 2013.

Contribution to the Understanding of Unexplained Death of Pasturing Horses in the North of Spain: A Retrospective Case Series
Abstract: The aim of this work was to study a retrospective case series of acute degenerative myopathy, which caused high mortality in adult horses grazing in a specific region of Spain, in relation to a possible etiopathogenesis. Outbreaks of myopathy occurred in December of 1999, 2003, 2009, and 2011 after an abrupt fall in temperatures and the first snowfalls. Ten horses were necropsied, and an exhaustive gross and histopathological examination was performed using specific histochemical stainings to evaluate muscle and cardiac damage. Intense myodegeneration, affecting the postural and respiratory muscles and the muscle...
Source: Journal of Equine Veterinary Science - September 17, 2012 Category: Veterinary Research Authors: Laura Polledo, Juan F. García Marín, Jorge González, Beatriz Martínez-Fernández, Laetitia Delgado, Valentín Pérez, Wenceslao Jiménez, Claudia Pérez-Martínez, M. Carmen Ferreras, M. José García-Iglesias Tags: Case Reports Source Type: research

Comprehensive Carrier Screening and Molecular Diagnostic Testing for Recessive Childhood Diseases
Clinical Scenarios The test is designed both for preconception carrier testing of couples wishing to start a family and for molecular diagnosis in children suspected of being affected by a recessive childhood disease. The published (research) version of the test included 448 childhood recessive illnesses with severe clinical manifestations1. A revised panel is undergoing clinical validation for use as a laboratory developed test (LDT) with an intention of being offered via a laboratory regulated by the Clinical Laboratory Improvement Amendments (CLIA). The clinical panel contains 595 childhood recessive diseases that are d...
Source: PLOS Currents Evidence on Genomic Tests - May 2, 2012 Category: Genetics & Stem Cells Authors: stephenkingsmore Source Type: research