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Procedure: Pulmonary Function Testing

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Total 287 results found since Jan 2013.

HLA-DRB and HLA-DQ genetic variability in patients with aspirin-exacerbated respiratory disease.
CONCLUSIONS: Results of this study suggest that HLA-DQB1*0302 and HLA-DRB1*04 and their related haplotypes are genes involved in predisposing patients to AERD, whereas HLA-DQB1*0301 and HLA-DRB1*011 have negative association with AERD. PMID: 25975240 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2015 Category: ENT & OMF Authors: Esmaeilzadeh H, Nabavi M, Amirzargar AA, Aryan Z, Arshi S, Bemanian MH, Fallahpour M, Mortazavi N, Rezaei N Tags: Am J Rhinol Allergy Source Type: research

Diagnosis of Sarcoidosis
Abstract The diagnosis of sarcoidosis, a systemic granulomatous disease, is based on a compatible clinical–radiological picture and the histological evidence of noncaseating granulomas. Other diseases mimicking sarcoidosis, mostly infections and other granulomatoses, have to be excluded. There is no single test for sarcoidosis, and the presence of granulomas alone does not establish the diagnosis. Symptoms of sarcoidosis are not specific and can be markedly different according to organ involvement and disease course. Respiratory symptoms and fatigue are the most common symptoms at any stage of disease. Histologi...
Source: Clinical Reviews in Allergy and Immunology - March 18, 2015 Category: Allergy & Immunology Source Type: research

Prognosis of adult asthma: a 7-year follow-up study.
CONCLUSION: According to these 7-year follow up data, the remission rate of asthma was 11.3%. Patients with younger age, younger onset, atopy, allergic rhinitis, and few comorbidities seemed to have a greater possibility of remission. PMID: 25771154 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - March 12, 2015 Category: Allergy & Immunology Authors: Sözener ZÇ, Aydın Ö, Mungan D, Mısırlıgil Z Tags: Ann Allergy Asthma Immunol Source Type: research

Clinical factors affecting discrepant correlation between asthma control test score and pulmonary function.
Authors: Park SY, Yoon SY, Shin B, Kwon HS, Kim TB, Moon HB, Cho YS Abstract The Asthma Control Test (ACT) score is widely used in asthma clinics, particularly with the recent emphasis on achievement and maintenance of optimal asthma control. However, this self-assessment score does not always correspond with lung function parameters, leading to uncertainty about each patient's control status; therefore, we investigated the clinical characteristics that are associated with discrepant correlation between the ACT score and pulmonary function. The 252 adult asthmatic subjects were divided into 5 groups according to th...
Source: Allergy, Asthma and Immunology Research - January 4, 2015 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

A randomized, double-blind, placebo-controlled of vitamin D3 for Irish children with asthma: Baseline data
Vitamin D deficiency (VDD) and asthma-incidence/severity share many common risk factors. Vitamin D has a number of biological effects that are likely important in regulating key mechanisms in asthma, including immunomodulatory effects as well as altering airway hyperresponsiveness, pulmonary function, airway smooth muscle-remodeling and response to anti-asthma therapy. Thus, VDD may result in increased prevalence and severity of childhood asthma.In Winter 2013-2014 we recruited 43 children (23 male), aged 5-15 (mean 8.7y) with a mean body mass index of 19.9kg/m2 (13 - 32.6) all previously diagnosed with asthma (Dublin, Ire...
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Kerley, C., Greally, P., Coughlan, D., Elnazir, B. Tags: 7.2 Paediatric Asthma and Allergy Source Type: research

Nasal and bronchial response to exercise in children with seasonal allergic rhinitis out of the pollen season
ConclusionThe prevalence of exercise‐induced nasal obstruction in children with seasonal rhinitis out of the pollen season is 40%. We showed that minimal persistent inflammation and nasal symptoms can also be diagnosed in rhinitis children in a symptom‐free period.
Source: International Forum of Allergy and Rhinology - December 1, 2014 Category: Allergy & Immunology Authors: Koray Harmancı, Barıs Urhan, Hülya Anıl, Abdulkadır Kocak Tags: ORIGINAL ARTICLE Source Type: research

Longitudinal increase in total IgE levels in patients with adult asthma: an association with poor asthma control
Conclusions: These data suggest that a longitudinal increase in total IgE is associated with both poor asthma control and Aspergillus-specific IgE in patients with adult asthma.
Source: Respiratory Research - November 20, 2014 Category: Respiratory Medicine Authors: Akihiko TanakaMegumi JinnoKuniaki HiraiYoshito MiyataHiroko MizumaMunehiro YamaguchiShin OhtaYoshio WatanabeMayumi YamamotoShintaro SuzukiTakuya YokoeMitsuru AdachiHironori Sagara Source Type: research

Influence of chronic sinusitis and nasal polyp on the lower airway of subjects without lower airway diseases.
CONCLUSIONS: CT findings suggesting chronic sinusitis and nasal polyp were associated with subclinical lower airway flow limitation even in the absence of underlying lung disease. PMID: 24991454 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 16, 2014 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Fractional exhaled nitric oxide and impulse oscillometry in children with allergic rhinitis.
CONCLUSIONS: Reversible airway obstruction on IOS and elevated FeNO levels were observed in children with AR. Because elevated FeNO levels can indicate airway inflammation and because chronic inflammation may lead to BHR, FeNO levels may be associated with BHR in AR. IOS can be a useful tool for detecting lower airway involvement of AR independent of BHR assessed in the MCT. PMID: 24404390 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 16, 2014 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Laryngopharyngeal symptoms in patients with asthma: a cross‐sectional controlled study
ConclusionLaryngopharyngeal reflux disease is more prevalent and more severe in patients with asthma vs controls.
Source: The Clinical Respiratory Journal - August 4, 2014 Category: Respiratory Medicine Authors: Abdul Latif Hamdan, Hussein Jaffal, Rachel Btaiche, Zaahir A. Turfe, Ibrahim Bawab, Nadim Kanj, Hani Tamim Tags: Original Article Source Type: research

Laryngopharyngeal symptoms in patients with asthma; A cross‐sectional controlled study
ConclusionLaryngopharyngeal reflux disease is more prevalent and more severe in patients with asthma vs. controls.
Source: The Clinical Respiratory Journal - July 3, 2014 Category: Respiratory Medicine Authors: Abdul Latif Hamdan, Hussein Jaffal, Rachel Btaiche, Zaahir A. Turfe, Ibrahim Bawab, Nadim Kanj Tags: Original Article Source Type: research

Reply
We would like to thank Dr Panasoff for his comment on our report of the EXACT trial (NCT00096954) of omalizumab, which studied patients with atopic asthma with preserved pulmonary function who remained symptomatic on inhaled corticosteroids with or without other controller medications. To clarify, this study was done as a postmarketing commitment from the US Food and Drug Administration in which we were to evaluate patients with atopic asthma and normal lung function. Atopic asthma was not determined solely based on serum IgE levels; patients also had to have positive skin test responses or in vitro (RAST or ImmunoCAP) ...
Source: Journal of Allergy and Clinical Immunology - March 31, 2014 Category: Allergy & Immunology Authors: Karin Rosén, William Busse Tags: Correspondence Source Type: research

Allergic rhinitis may impact the recovery of pulmonary function tests after moderate/severe asthma exacerbation in children
ConclusionsRecovery of PFTs during a moderate/severe asthma exacerbation may take up to 4 weeks. Apart from severity of the exacerbation, AR is a significant factor affecting the recovery time of PFTs and therefore may impact asthma management. This issue reinforces the combined treatment of AR and asthma.
Source: Allergy - March 20, 2014 Category: Allergy & Immunology Authors: O. Yilmaz, A. Bakirtas, H. I. Ertoy Karagol, E. Topal, M. S. Demirsoy Tags: Original Article Source Type: research

Vitamin e supplementation, lung functions and clinical manifestations in children with moderate asthma: a randomized double blind placebo- controlled trial.
Abstract Asthma is the most common chronic inflammatory disorder characterized by cough, wheezing and dyspnea in children. Nutrition is an important factor which influences on induction and exacerbation of asthma. There are controversies to use Vitamin E in asthmatic patients. The aim of this study was to evaluate the effect of vitamin E supplement in children with moderate asthma. This is a randomized double blind placebo-controlled trial performed on children (age 2-17 years old) with moderate asthma (5-17 years old) from March 2010 to March 2012. Case group were treated with fluticasone and vitamin E (50mg/day)...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 19, 2013 Category: Allergy & Immunology Authors: Ghaffari J, Farid Hossiani R, Khalilian A, Nahanmoghadam N, Salehifar E, Rafatpanah H Tags: Iran J Allergy Asthma Immunol Source Type: research

Long‐term results of endoscopic sinus surgery–oriented treatment for chronic rhinosinusitis with asthma
ConclusionsFESS‐oriented multimodality treatment improves CRS with asthma significantly and persistently. Asthma control level improved. Antiasthma medication use and pulmonary function remained stable. Level of Evidence4 Laryngoscope, 2013
Source: The Laryngoscope - August 5, 2013 Category: ENT & OMF Authors: Feng‐hong Chen, Ke‐jun Zuo, Yu‐biao Guo, Zhi‐ping Li, Geng Xu, Rui Xu, Jian‐bo Shi Tags: Allergy/Rhinology Source Type: research