Nimodipine improves vocal fold and facial motion recovery after injury: A systematic review and meta ‐analysis
IntroductionNimodipine is a calcium channel blocker that has been used to treat hypertension and vasospasm. Emerging evidence in the literature suggests that it is neuroprotective by reducing cellular apoptosis after neuronal injury and promoting axonal sprouting at the nodes of Ranvier.ObjectivesTo conduct a systematic review of the usage of nimodipine in cranial nerve injury and to perform a meta ‐analysis to estimate the efficacy of nimodipine on functional recovery of the injured cranial nerves.MethodsLiterature search was performed in eight databases using preferred reporting items for systematic reviews and meta an...
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: R. Jun Lin, Michele Klein ‐Fedyshin, Clark A. Rosen Tags: Laryngology Source Type: research

Mortality associated with tracheostomy complications in the United States: 2007 –2016
ConclusionsTracheostomy ‐related complications were implicated in the deaths of a significant number of individuals. Several demographic groups had increased likelihood of tracheostomy‐related mortality. Future research is necessary to develop targeted interventions to decrease harm.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: John D. Cramer, Evan M. Graboyes, Michael J. Brenner Tags: General Otolaryngology Source Type: research

Ultrasonographic assessment of costochondral cartilage for microtia reconstruction
The Laryngoscope, EarlyView. (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Jessa E. Miller, Janice L. Farlow, Elizabeth M. Knecht, Ramon Sanchez, Jennifer C. Kim, David A. Zopf Tags: Facial Plastics/Reconstructive Surgery Source Type: research

Experimental animal model for assessment of tracheal epithelium regeneration
ConclusionWe present an experimental in vivo animal model of tracheal epithelium injury and recovery. It can be effectively used with certain further modifications as a basis for routine testing of bioengineered constructs.Level of EvidenceNA.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Elizaveta I. Safronova, Sergey S. Dydykin, Evgeny D. Grigorevskiy, Ekaterina A. Tverye, Stepan I. Kolchenko, Natalia N. Piskunova, Anna V. Denisova, Galina P. Titova, Vladimir D. Parshin, Olga A. Romanova, Andrey A. Panteleyev Tags: Head and Neck Source Type: research

Changing trends in management of vestibular schwannoma: A National Cancer Database study
ObjectiveTo describe changes in management trends of vestibular schwannoma (VS) and the effects of median income, education level, insurance status, and tumor size on receipt of treatment.MethodsCross ‐sectional analysis using the National Cancer Database from 2004 to 2014. All patients with a diagnosis of VS were identified between 2004 and 2014. Trends in treatment modality over time were analyzed. Correlation between demographics, institution type, median income, education level, and insuran ce status were assessed using univariate and multivariate logistic regressions.ResultsOf the 22,290 VS patients identified, 16,0...
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Bassel Bashjawish, Suat K ılıç, Soly Baredes, Jean Anderson Eloy, James K. Liu, Yu‐Lan Mary Ying Tags: Otology/Neurotology Source Type: research

Endoscopic endonasal resection of adenoid cystic carcinoma of the sinonasal tract and skull base
ConclusionsThe endoscopic approach is safe and effective for selected sinonasal ACC, reducing the comorbidities of the external approaches while producing similar oncological results. High T ‐stage, grade III histology, positive surgical margins, and perineural infiltration all have an important negative prognostic value.Level of Evidence4.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Luca Volpi, Maurizio Bignami, Davide Lepera, Apostolos Karligkiotis, Andrea Pistochini, Giorgia Ottini, Elena Grigioni, Davide Lombardi, Piero Nicolai, Paolo Castelnuovo Tags: Cranial Base Source Type: research

Characterization of aged rat vocal fold fibroblasts
ConclusionsThe following possible characteristics of aged VFFs were implied: long duration of mitosis, increased myofibroblast population size with certain dysfunctions, reduced type I collagen turnover, and correlation between α‐SMA expression and type I collagen metabolism. Further investigations of these features will help to clarify presbyphonia's pathology and establish treatment strategies.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Yoshitaka Kawai, Yo Kishimoto, Tohru Sogami, Ryo Suzuki, Takuya Tsuji, Nao Hiwatashi, Ichiro Tateya, Shin ‐Ichi Kanemaru, Tatsuo Nakamura, Koichi Omori, Shigeru Hirano Tags: Laryngology Source Type: research

Pediatricians ’ proficiency in the care of the dysphonic child
ConclusionsVeteran pediatricians feel more comfortable diagnosing a voice disorder and are more likely to refer a DC, regardless of patient/parent complaints or compounding factors. Pediatricians are most likely to refer to a pediatric otolaryngologist versus a voice specialist. These findings suggest that education of younger, less ‐experienced pediatricians about recognizing voice disorders and options for referral is needed. This may improve the overall care of the DC.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Carly S. Schiff, Karen B. Zur, Lisa M. Biggs, Jia Guo, Michael J. Pitman Tags: Laryngology Source Type: research

Osteoradionecrosis of the sternoclavicular joint after laryngopharyngeal radiation
ConclusionIntegrating cases of sternoclavicular joint ORN promotes awareness of atypical laryngopharyngeal radiation complications, elucidates contributing factors, educates physicians on presentation and management, and provides a platform for prospective investigation.Level of Evidence4.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Rachel Irizarry, Deborah R. Shatzkes, Stephanie Teng, Nikita Kohli, Gady Har ‐El Tags: Head and Neck Source Type: research

Can Pharyngeal Packing Prevent Postoperative Nausea and Vomiting in Nasal Surgery?
ConclusionsConsidering the occurrence of postoperative morbidity according to the time course, pharyngeal packing during nasal surgery does not alleviate PONV but instead could aggravate postoperative throat pain. Additionally, pharyngeal packing has the possibility of airway problem such as the foreign body aspiration. Based on our results, we suggest that there is no need to place a pharyngeal pack to prevent PONV in patients undergoing nasal surgery.Level of EvidenceIb.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Ho Joon Jin, Subin Kim, Se Hwan Hwang Tags: Allergy/Rhinology Source Type: research

Mucocele formation following laryngeal cleft injection
A 12 ‐month‐old male underwent injection laryngoplasty for dysphagia associated with a deep interarytenoid notch. He subsequently developed a large postcricoid mucocele requiring revision surgery and marsupialization of the cyst just 2 weeks following the initial surgery.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: C. Burton Wood, Alexis K. Rieber, Edward B. Penn Tags: Pediatrics Source Type: research

Voice outcomes after endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyposis
ConclusionsSuccessful treatment of sinonasal disease can help to improve voice outcomes in patients with CRSwNP. There are inherent differences in the long ‐term outcomes of the results beyond 3 months based on practice patterns of ongoing medical management, but our results are interesting in that they show early improvement in voice outcomes.Level of Evidence2bLaryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 19, 2018 Category: ENT & OMF Authors: Christian A. Hall, Stephen C. Hernandez, Rachel A. Barry, Brittany A. Zito, Andrew J. McWhorter, Daniel S. Fink, Henry P. Barham Tags: Allergy/Rhinology Source Type: research

Cutaneous squamous cell carcinoma metastasis to the parotid region lymph nodes
ObjectiveTo determine the effect on survival of periauricular region cutaneous squamous cell carcinomas (cSCC) metastasizing to parotid region and cervical lymph nodes.MethodsFrom May 1995 to October 2013, consecutive patients with cSCC undergoing parotidectomy/neck dissection  ≥ 18 years without distant metastasis were included. Demographic, clinical, and pathologic data were analyzed. Uni‐ and multivariate analyses of disease‐specific survival and overall survival were performed. Statistical significance was set atP 
Source: The Laryngoscope - November 16, 2018 Category: ENT & OMF Authors: Larry L. Myers, Chul Ahn Tags: Head and Neck Source Type: research

Voice therapy associated with a decrease in the reflux symptoms index in patients with voice complaints
ConclusionsIn this study of patients with muscle tension dysphonia or vocal hyperfunction not responsive to antireflux therapy, RSI and VHI ‐10 scores improved following voice therapy. Results suggest that self‐reported symptoms typically attributed to laryngopharyngeal reflux disease may actually be secondary to inefficient voice use patterns or anxiety about dysphonia that are responsive to voice therapy.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 16, 2018 Category: ENT & OMF Authors: Sarah L. Schneider, Matthew Clary, Daniel Steven Fink, Sean X. Wang, Farshad N. Chowdhury, Rena Yadlapati, Marie E. Jett é, Mark S. Courey Tags: Laryngology Source Type: research

Are chronic cough and laryngopharyngeal reflux more common in obstructive sleep apnea patients?
ConclusionsOSA patients demonstrate worse chronic cough and LPR ‐related quality of life versus non‐OSA patients. Furthermore, the severity of these quality‐of‐life measures was correlated with the severity of the AHI. Chronic cough and particularly the pharyngeal LPR symptoms may be associated with the presence and severity of OSA.Level of Evidence2 .Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 15, 2018 Category: ENT & OMF Authors: Christopher J. Gouveia, Amulya Yalamanchili, Saied Ghadersohi, Caroline P. E. Price, Michiel Bove, Hrayr P. Attarian, Bruce K. Tan Tags: Sleep Medicine Source Type: research

Dysfunctional hypoglossal nerve stimulator after electrical cardioversion: A case series
ConclusionCounseling for patients with HGNS undergoing external electrical cardioversion should include possible device damage and need for operative replacement. Anteroposterior electrode pad placement should be considered for patients with HGNS who require electrocardioversion. Operative replacement of an HGNS system damaged by electrocardioversion begins with IPG replacement and intraoperative device interrogation.Level of Evidence4.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 15, 2018 Category: ENT & OMF Authors: Adam P. Vasconcellos, Colin T. Huntley, Amy E. Schell, Ryan J. Soose, Maurits S. Boon Tags: Sleep Medicine Source Type: research

Real ‐time robotic airway measurement: An additional benefit of a novel steady‐hand robotic platform
ObjectiveDescribe the secondary capability of a robotic system to provide real ‐time measurements of airway dimensions with high fidelity.MethodsSeven unique phantoms of laryngotracheal stenosis (LTS) were modeled using a computer ‐aided design tool and were three dimensionally printed. These stenoses were of different dimensions and orientations, and some were purposefully oblique. The dimensions of the stenoses were then measured with the novel Robotic ENT (Ear, Nose, and Throat) Microsurgery System (REMS; Galen Robotics, Inc., Sunnyvale, CA) because it is capable of tool position memory in three dimensional (3D) spa...
Source: The Laryngoscope - November 15, 2018 Category: ENT & OMF Authors: Christopher R. Razavi, Francis X. Creighton, Paul R. Wilkening, Joseph Peine, Russell H. Taylor, Lee M. Akst Tags: Bronchoesophagology Source Type: research

Evolving phenotype of the head and neck surgeon
ConclusionOur findings suggest that the modern H&N surgeon is increasingly becoming an endocrine and H&N surgeon. The proportion of endocrine surgeries performed in residency, which serves as a surrogate for H&N practices, has more than doubled over the past 20 years and now represents the largest subcategory of H&N surgery.Level of EvidenceNA.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 15, 2018 Category: ENT & OMF Authors: Seth Kay, Robert Miller, Dennis Kraus, David J. Terris Tags: Thyroid/Parathyroid Source Type: research

Impact of a Formal Patient Safety and Quality Improvement Curriculum: A Prospective, Controlled Trial
ConclusionImplementing a formal curriculum dedicated to PSQI led to an improvement in PSQI ‐related project development confidence and PSQI knowledge. Attitudes toward safety did not improve over the course of a year. Longer‐term studies involving multiple institutions and other interventions are needed to evaluate the impact and duration of changes that occur.Level of Evidence1b.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 15, 2018 Category: ENT & OMF Authors: Nausheen Jamal, Sarah N. Bowe, Michael J. Brenner, Karthik Balakrishnan, John P. Bent Tags: General Otolaryngology Source Type: research

Long ‐term swallowing performance following transoral robotic surgery for obstructive sleep apnea
ConclusionsBOT reduction via TORS has a negative effect on long ‐term swallowing function. A self‐assessment questionnaire can help detect patients who suffer from swallowing impairment. Postoperative objective swallowing tests are essential not only in the immediate postoperative period but also during late routine follow‐up. Proper patient selection and detailed information about surgery and possible late‐swallowing effect are important factors before scheduling BOT reduction via TORS for OSA treatment.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 15, 2018 Category: ENT & OMF Authors: Miki Paker, Irit Duek, Faten Awwad, Limor Benyamini, Tsipi Meshyeev, Ziv Gil, Jacob T. Cohen Tags: Laryngology Source Type: research

Tracheostomy demographics and outcomes among pediatric patients ages 18 years or younger —United States 2012
ConclusionsPediatric tracheostomies are associated with significant hospital utilizations, complications, and mortality. Increased risk of mortality is observed among neonates and infants. Continued study of tracheostomy outcomes among these subsets of the pediatric population are warranted.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 15, 2018 Category: ENT & OMF Authors: Mark Sakai, Yann ‐Fuu Kou, Gopi B. Shah, Romaine F. Johnson Tags: Pediatrics Source Type: research

Sex bias: Is it pervasive in otolaryngology clinical research?
The objective was to determine whether sex bias is present in otolaryngology and whether sex is appropriately analyzed as an independent variable in otolaryngology clinical research.Study DesignLiterature review.MethodsWe systematically reviewed all 2016 articles in three major otolaryngology journals:The Laryngoscope, JAMA Otolaryngology –Head and Neck Surgery, and Otolaryngology–Head and Neck Surgery. Extracted data included study origin, location, subspecialty, number/sex of subjects, ≥50% sex matching (SM≥50), and sex ‐based statistical analysis.ResultsSix hundred of 1,209 articles comprising origin...
Source: The Laryngoscope - November 15, 2018 Category: ENT & OMF Authors: Zainab Farzal, Elizabeth D. Stephenson, Lauren A. Kilpatrick, Brent A. Senior, Adam M. Zanation Tags: General Otolaryngology Source Type: research

Pleomorphic adenoma of the head and neck in children: presentation and management
ConclusionEvaluation of pleomorphic adenoma in children should include preoperative imaging. The goal of surgery should be complete surgical excision with negative margins. Rate of recurrence is low; however, prolonged monitoring is recommended.Level of Evidence4.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 15, 2018 Category: ENT & OMF Authors: Natasha D. Dombrowski, Nikolaus E. Wolter, Alexandria L. Irace, Michael J. Cunningham, Sara O. Vargas, Antonio R. Perez ‐Atayde, Caroline D. Robson, Reza Rahbar Tags: Pediatrics Source Type: research

Defining differences in patient characteristics between spasmodic dysphonia and laryngeal tremor
ObjectiveTo compare presenting characteristics of patients with adductor spasmodic dysphonia (ADSD), ADSD with laryngeal tremor (ADSD  + LT), and laryngeal tremor without ADSD (LT).DesignCross ‐sectional analysis.MethodsPatients treated for laryngeal movement disorders (1990 –2016) were included. Analysis of variance and chi square tests measured differences in patient characteristics across the three disease groups. Using ADSD as the referent, multivariable logistic regression models were used to determine whether potential risk factors including patient demographics , family history, presence of pot...
Source: The Laryngoscope - November 13, 2018 Category: ENT & OMF Authors: Priyesh N. Patel, Edmond K. Kabagambe, Jennifer C. Starkweather, Matthew Keller, Zaki A. Ahmed, Simone C Gruber, Jordan S Akins, C. Gaelyn Garrett, David O. Francis Tags: Laryngology Source Type: research

Curcumin gum formulation for prevention of oral cavity head and neck squamous cell carcinoma
Objectives/HypothesisHead and neck squamous cell carcinoma represents the sixth most common cancer. As a result of field cancerization, second primaries and recurrences are high. Hence, research has focused on chemoprevention. Curcumin, a polyphenol compound with anticarcinogenic properties, is one such promising nutraceutical. As poor bioavailability limits curcumin's use, a novel gum formulation was tested allowing for direct mucosal absorption into the bloodstream. This preliminary study validates curcumin gum efficacy by assessing release and transmucosal absorption, along with measuring its effects on serum cytokine l...
Source: The Laryngoscope - November 13, 2018 Category: ENT & OMF Authors: Lindsay Boven, Sean P. Holmes, Brian Latimer, Kenneth McMartin, Xiaohui Ma, Tara Moore ‐Medlin, Alok R. Khandelwal, Jerry McLarty, Cherie‐Ann O. Nathan Tags: Head and Neck Source Type: research

Extranodal extension in resected oral cavity squamous cell carcinoma: more to it than meets the eye
ConclusionIn patients with ENE and advanced nodal disease, T stage, N stage, stage group, depth, and pattern of invasion lose their impact on OS. In patients with ENE, nodal characteristics such as LND, the number of nodes with ENE, and grade of ENE serve as important prognosticators and aid in further risk stratification.Level of Evidence4.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 13, 2018 Category: ENT & OMF Authors: Jai Prakash Agarwal, Shubhada Kane, Sarbani Ghosh ‐Laskar, Avinash Pilar, Vishal Manik, Nikita Oza, Pranjali Wagle, Tejpal Gupta, Ashwini Budrukkar, Vedang Murthy, Monali Swain Tags: Head and Neck Source Type: research

T ‐Helper 2 Lymphocyte Immunophenotype Is Associated With Iatrogenic Laryngotracheal Stenosis
Objective/HypothesisThis prospective controlled human and murine study assessed the presence of inflammatory cells and cytokines to test the hypothesis that immune cells are associated with fibroproliferation in iatrogenic laryngotracheal stenosis (iLTS).MethodsInflammation was assessed by histology and immunofluorescence (IF), quantitative real ‐time polymerase chain reaction (qRT‐PCR), and flow cytometry of cricotracheal resections of iLTS patients compared to normal controls. An iLTS murine model assessed the temporal relationship between inflammation and fibrosis.ResultsiLTS specimens showed increased inflammation ...
Source: The Laryngoscope - November 13, 2018 Category: ENT & OMF Authors: Alexander T. Hillel, Dacheng Ding, Idris Samad, Michael K. Murphy, Kevin Motz Tags: Laryngology Source Type: research

Gamification as a tool for resident education in otolaryngology: A pilot study
The Laryngoscope, EarlyView. (Source: The Laryngoscope)
Source: The Laryngoscope - November 13, 2018 Category: ENT & OMF Authors: David Alexander, Michelle Thrasher, Brian Hughley, Bradford A. Woodworth, William Carroll, James H. Willig, Do ‐Yeon Cho Tags: General Otolaryngology Source Type: research

Quantification of injection force mechanics during injection laryngoplasty
ObjectivesIn ‐office or operative injection laryngoplasty requires needle stability for accurate material placement. To date, no reports compare injection forces based on needle gauge, bends, length, or material type or temperature. We hypothesize these factors alter injection forces and could impact clinical use.MethodsSwine larynges were placed in a compression testing machine. Syringes were affixed to a stabilizing crossbeam. Straight needles (25G 1.5 ‐inch; 27G 1.25‐inch; or 9.8‐inch malleable shaft 16G per oral with 24G tapered needle tip) were inserted into the swine vocal folds to simulate realistic tissue r...
Source: The Laryngoscope - November 13, 2018 Category: ENT & OMF Authors: Joseph J. Pearson, Alexandra S. Ortiz, Sergio Montelongo, C. Blake Simpson, Teja Guda, Gregory R. Dion Tags: Laryngology Source Type: research

Anterior laryngeal electrodes for recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: New expanded options for neural monitoring
ConclusionsCompared to ETT surface electrodes, the ALEs provide similar and stable electromyographic responses with equal sensitivity for recording evoked responses during neural monitoring in thyroid and parathyroid surgery. The ALEs offer significantly more robust monitoring of the external branch of the superior laryngeal nerve. Furthermore, ALEs are contained within the operative field, are totally surgeon controlled, and are unaffected by the potential vicissitudes of ETT position during surgery.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 12, 2018 Category: ENT & OMF Authors: Whitney Liddy, Bradley R. Lawson, Samuel R. Barber, Dipti Kamani, Mohamed Shama, Selen Soylu, Che Wei Wu, Feng ‐Yu Chiang, Joseph Scharpf, Marcin Barczynski, Henning Dralle, Sam Van Slycke, Rick Schneider, Gianlorenzo Dionigi, Gregory W. R Tags: Thyroid/Parathyroid Source Type: research

Postoperative respiratory complications and racial disparities following inpatient pediatric tonsillectomy: A cross ‐sectional study
Objectives/HypothesisTo study rates of respiratory complications/interventions among inpatient tonsillectomy patients in the United States and identify risk factors for these events.Study DesignRetrospective database review.MethodsChildren (age  
Source: The Laryngoscope - November 9, 2018 Category: ENT & OMF Authors: Yann ‐Fuu Kou, Mark Sakai, Gopi B. Shah, Ron B. Mitchell, Romaine F. Johnson Tags: Pediatrics Source Type: research

Continuous laryngoscopy during provocation in the assessment of inducible laryngeal obstruction
The Laryngoscope, EarlyView. (Source: The Laryngoscope)
Source: The Laryngoscope - November 9, 2018 Category: ENT & OMF Authors: James Harry Hull, Emil Schwarz Walsted, Johanna Feary, Paul Cullinan, Guy Scadding, Emma Bailey, Julia Selby Tags: Laryngology Source Type: research

Magnetic resonance imaging with cochlear implants and auditory brainstem implants: Are we truly practicing MRI safety?
ConclusionOur series offers a diverse number of CI manufacturers and is in accordance with other literature that CI MRI ‐related adverse events are occurring at an unacceptable frequency. We can promote CI MRI safety through our institutions' MRI CI patient protocols, raise awareness that diagnostic MRI benefits must outweigh CI‐related complications, and advocate for continued industry technological innovation.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 9, 2018 Category: ENT & OMF Authors: Matthew Shew, Helena Wichova, James Lin, Luke N. Ledbetter, Hinrich Staecker Tags: Otology/Neurotology Source Type: research

Suture ‐ligature technique for the closure of tracheocutaneous fistula in adults
The Laryngoscope, EarlyView. (Source: The Laryngoscope)
Source: The Laryngoscope - November 9, 2018 Category: ENT & OMF Authors: Samantha J. Hauff, Simon Brisebois, William Moss, Albert L. Merati, Philip A. Weissbrod Tags: Laryngology Source Type: research

Preclinical assessment of resorbable silk splints for the treatment of pediatric tracheomalacia
The objective of this pilot study is to assess the safety and efficacy of silk fibroin‐based splints in a clinically relevant preclinical model of tracheomalacia.MethodsSilk splints were evaluated in a surgically induced model of severe tracheomalacia in N  = 3 New Zealand white rabbits for 17, 24, and 31 days. An image‐based assay was developed to quantify the dynamic change in airway area during spontaneous respiration, and histopathology was used to study the surrounding tissue response.ResultsThe average change in area in the native trachea was 23% during spontaneous respiration; surgically induced tr...
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Meghan McGill, Nikhila Raol, Kevin S. Gipson, Sarah N. Bowe, Jackson Fulk ‐Logan, Anahita Nourmahnad, Joon Yong Chung, Michael J. Whalen, David L. Kaplan, Christopher J. Hartnick Tags: Pediatrics Source Type: research

Optimal resection margin for head and neck cutaneous melanoma
ConclusionsThe survival of patients with cutaneous melanoma of the head and neck depends on age, depth of tumor invasion, and histology. Within the head and neck, a wider resection margin of>2 cm does not confer any additional survival benefit compared with a narrower margin. Future studies should examine whether wider surgical margins would confer survival benefit in local or recurrent melanoma.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Albert Y. Han, Suraj Dhanjani, Kelly Pettijohn, Pratik B. Patel, Maie A. St. John Tags: Head and Neck Source Type: research

Activity of swallowing ‐related neurons in the medulla in the perfused brainstem preparation in rats
ConclusionsThe perfused brainstem preparation of rat fully preserves the Sw ‐CPG. The recorded cellular activities and general topographical organization of swallowing neurons are in accordance with previous in vivo studies. Thus, the perfused brainstem preparation is an ideal experimental model to advance the understanding of neuronal mechanisms underlying swallowing.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Keiko Hashimoto, Yoichiro Sugiyama, Shinya Fuse, Toshiro Umezaki, Yoshitaka Oku, Mathias Dutschmann, Shigeru Hirano Tags: Laryngology Source Type: research

The epidemiology of autologous tissue grafting in primary and revision rhinoplasty
ConclusionsCartilaginous or bony grafting is a critical surgical technique in both primary and secondary rhinoplasties. This is the first study to examine percentages of site ‐specific autologous grafting from auricular and costal donor sites for primary and revision cases. Gender and age‐specific trends associated with specific grafting sites are also identified. These data are important to help guide preoperative counseling and informed consent for all rhinoplasty surgeries.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Linda N. Lee, Olivia Quatela, Neil Bhattacharyya Tags: Facial Plastics/Reconstructive Surgery Source Type: research

Sex bias in basic science and translational otolaryngology research
ConclusionsSex may influence outcomes significantly but is underreported and underanalyzed in basic/translational otolaryngology research. Because this research frequently lays the groundwork for clinical trials and standards of care, future research must address these sex ‐based discrepancies.Level of EvidenceNALaryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Elizabeth D. Stephenson, Zainab Farzal, Lauren A. Kilpatrick, Brent A. Senior, Adam M. Zanation Tags: General Otolaryngology Source Type: research

Automated Indentation Mapping of Vocal Fold Structure and Cover Properties Across Species
ConclusionsAutomated indentation mapping yielded reproducible biomechanical property measurement of the VF cover and intact VF. Divergent VF structural properties across canine, swine, and leporine species were observed.Level of EvidenceNA.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Gregory R. Dion, Jean ‐Francois Lavoie, Paulo Coelho, Milan R. Amin, Ryan C. Branski Tags: Laryngology Source Type: research

Glottic exposure for transoral laser microsurgery: Proposal of a mini ‐version of the laryngoscore
ConclusionOur validation confirmed the predictive ability of the Laryngoscore. Furthermore, although composed of only three clinical parameters, the mLS was still able to convey useful information regarding the possibility of obtaining GLE.Level of Evidence2.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Fabiola Incandela, Alberto Paderno, Francesco Missale, Andrea Laborai, Marta Filauro, Francesco Mora, Francesca Del Bon, Cesare Piazza, Giorgio Peretti Tags: Laryngology Source Type: research

Impact of pretreatment growth on Tumor control for vestibular schwannomas following gamma knife
ConclusionsPretreatment growth was not associated with increased salvage treatment or posttreatment radiographic progression rates in VS following GK.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Joseph Chang, Jonathan D. Breshears, Annette M. Molinaro, Penny K. Sneed, Michael W. McDermott, Philip V. Theodosopoulos, Aaron D. Tward Tags: Otology/Neurotology Source Type: research

What defines asymmetric sensorineural hearing loss?
The Laryngoscope, EarlyView. (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Nedim Durakovic, Michael Valente, Joel A. Goebel, Cameron C. Wick Tags: Otology/Neurotology Source Type: research

I dream of Gini: Quantifying inequality in otolaryngology residency interviews
ConclusionThere is an unequal distribution of interview invitations, which likely reflects the reality of asymmetry in applicant competitiveness. Otolaryngology demonstrates the greatest equality in distribution, which may stem from a greater burden of hoarding. The specialty's perceived competitiveness mitigates factors such as cost and time, essentially encouraging more people to take as many interviews as they can.Level of EvidenceNA.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Andrew H. Lee, Patrick Young, Ross Liao, Paul H. Yi, Douglas Reh, Simon R. Best Tags: General Otolaryngology Source Type: research

Real steak knives of cincinnati: Repeated foreign body ingestion with novel endoscopic removal
We report a 32 ‐year‐old female patient with history of multiple previous foreign body ingestions requiring several past exploratory laparotomies, who presents with a knife blade in the esophagus. We present a novel method of using a rigid cervical esophagoscope with a salivary bypass tube. The tip of the knif e was isolated into the cervical esophagoscope, and the salivary bypass tube advanced off the cervical esophagoscope over the knife, shielding the serrated edge during removal preventing laceration to the esophagus. (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Erin Harvey, David Lee, John Paul Giliberto Tags: Laryngology Source Type: research

Measurement reliability of phonation threshold pressure in pediatric subjects
Objectives/HypothesisPhonation threshold pressure (PTP), the minimum subglottal pressure (Ps) required for phonation, is sensitive to changes in laryngeal biomechanics and is often elevated with pathology. Little is reported on PTP in children; challenges with task performance and measurement reliability represent barriers to routine clinical assessment.Study DesignPilot study evaluating PTP and Ps measurement reliability in children using labial and mechanical interruption.MethodsTwenty ‐two subjects aged 4 to 17 years (10.7 ± 3.9 years) participated. Ten trials were performed for each method; task ...
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Matthew R. Hoffman, Austin J. Scholp, Calvin D. Hedberg, Jim R. Lamb, Maia N. Braden, J. Scott McMurray, Jack J. Jiang Tags: Pediatrics Source Type: research

Canal wall up surgery with mastoid and epitympanic obliteration in acquired cholesteatoma
ConclusionsObliteration of the epitympanum and mastoid is a reliable and safe technique following CWU surgery for cholesteatoma, resulting in low residual and recurrence rates.Level of Evidence4Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Catharine A. Hellingman, Simon Geerse, Maarten J. F. de Wolf, Fenna A. Ebbens, Erik van Spronsen Tags: Otology/Neurotology Source Type: research

Evaluation of early oral cavity cancer treatment quality at a single institution
ConclusionUsing the process quality measures proposed by the AHNS, adherence to the process quality measures for early ‐stage oral cavity cancer care at a tertiary care center was successfully evaluated. In general, good compliance with the proposed process quality measures was found and several areas for improvement were identified.Level of Evidence2c.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Steven Chang, Ryan Sanii, Hamad Chaudhary, Carol Lewis, Michael Seidman, Kathleen Yaremchuk Tags: Head and Neck Source Type: research

Topical Application of 5 ‐Aminolevulinic Acid Is Sufficient for Photodynamic Therapy on Vocal Folds
ConclusionTopical PDT with laryngeal spraying of 20% 5 ‐ALA solution achieves sufficient therapeutic effects and is potentially applicable for the treatment of vocal fold leukoplakia.Level of EvidenceNA.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Chi Zhang, Ting Gong, Jiajia Wang, Adriana Chou, Jack J. Jiang Tags: Laryngology Source Type: research

Does anatomic subsite influence oral cavity cancer mortality? A SEER database analysis
ConclusionAmong OCSCC patients, those with oral tongue cancer are more likely to experience CSM than patients with floor of mouth, upper gum, and retromolar trigone cancer. It is important to understand these mortality related differences in the management of OCSCC patients. Understanding subsite ‐specific mortality may benefit prognosis counseling of OCSCC patients and elicit subsite‐directed research as a means to improve outcomes.Level of EvidenceNA.Laryngoscope, 2018 (Source: The Laryngoscope)
Source: The Laryngoscope - November 8, 2018 Category: ENT & OMF Authors: Zachary Farhood, Matthew Simpson, Gregory M. Ward, Ronald J. Walker, Nosayaba Osazuwa ‐Peters Tags: Head and Neck Source Type: research