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Total 24197 results found since Jan 2013.

 In-vitro anticancer activity of Rauvolfia tetraphylla extract on mcf-7 breast cancer cell lines
Bioinformation. 2023 Jan 31;19(1):43-47. doi: 10.6026/97320630019043. eCollection 2023.ABSTRACTThe medicinal herb Rauwolfia tetraphylla is utilized by South Indian tribes to treat various medical ailments, although its cytotoxicity action has not been studied. As a result, the emphasis of the current investigation is on the anticancer activity of Rauvolfia tetraphylla extracts on MCF-7 breast cancer cell lines, as well as their effects on the levels of gene expression for BCl2 and TGF. The study found that the anticancer activity of R. tetraphylla extract demonstrated significant cytotoxic activity against MCF-7 breast can...
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Abraham Sabu Selvaraj J Gayatridevi R Dilipan E Source Type: research

Current appraises of therapeutic applications of nanocurcumin: A novel drug delivery approach for biomaterials in dentistry
Environ Res. 2023 Sep 15:116971. doi: 10.1016/j.envres.2023.116971. Online ahead of print.ABSTRACTCurcumin is a natural herb and polyphenol that is obtained from the medicinal plant Curcuma longa. It's anti-bacterial, anti-inflammatory, anti-cancer, anti-mutagenic, antioxidant and antifungal properties can be leveraged to treat a myriad of oral and systemic diseases. However, natural curcumin has weak solubility, limited bioavailability and undergoes rapid degradation, which severely limits its therapeutic potential. To overcome these drawbacks, nanocurcumin (nCur) formulations have been developed for improved biomaterial ...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Ranjeet A Bapat Sumit V Bedia Aarti S Bedia Ho Jan Yang Suyog Dharmadhikari Anshad Mohamed Abdulla Tanay V Chaubal Prachi R Bapat Shahabe Saquib Abullais Shadma Wahab Prashant Kesharwani Source Type: research

Product maturation and antibiotic resistance genes enrichment in food waste digestate and Chinese medicinal herbal residues co-composting
This study proposed co-composting of Chinese medicinal herbal residues (CMHRs) and FWD as a means to improve the maturation performance and investigated the evolution of antibiotic resistance genes (ARGs). Results demonstrated that CMHRs addition effectively accelerated the maturity of FWD composting to less than 35 days, remarkably removed its remaining antibiotics by 83.0% and promoted the formation of humification substances. However, both quantitative PCR and 16S rRNA sequencing analysis indicated that a significant enrichment of ARGs and mobile genetic elements including frA1, tetX, blaTEM, InuB-01, aadA2-02 and IntI-...
Source: Bioresource Technology - September 17, 2023 Category: Biotechnology Authors: Mengyu Cai Guihan Dong Yuting Zhou Caiyun Yang Hao Wu Chunyu Guo Haoran Zhang Ying Han Source Type: research

Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE -/- mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis
CONCLUSION: Our findings suggest that ZCHP can effectively attenuate AS progression by inhibiting MAPK/ERK signaling-mediated apoptosis via FGFR3 hypermethylation in the promoter region.PMID:37716492 | DOI:10.1016/j.jep.2023.117188
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Yan Zhang Dandan Li Zijun Jia Jun Mei Ya Wang Ying Zhang Qingbing Zhou Fengqin Xu Source Type: research

Dioscorea nipponica Makino: A comprehensive review of its chemical composition and pharmacology on chronic kidney disease
Biomed Pharmacother. 2023 Sep 14;167:115508. doi: 10.1016/j.biopha.2023.115508. Online ahead of print.ABSTRACTChronic kidney disease (CKD) is a widespread ailment that significantly impacts global health. It is characterized by high prevalence, poor prognosis, and substantial healthcare costs, making it a major public health concern. The current clinical treatments for CKD are not entirely satisfactory, leading to a high demand for alternative therapeutic options. Chinese herbal medicine, with its long history, diverse varieties, and proven efficacy, offers a promising avenue for exploration. One such Chinese herbal medici...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 16, 2023 Category: Drugs & Pharmacology Authors: Chenguang Wu Rui Zhang Jingjing Wang Yao Chen Wenhui Zhu Xiang Yi Yan Wang Lifan Wang Peng Liu Ping Li Source Type: research

Luteolin inhibits A549 cells proliferation and migration by down-regulating androgen receptors
CONCLUSION: In this study, we have explored luteolin as one of the active components of YQG, and may inhibit the proliferation and migration of A549 cells by decreasing the expression of AR and the regulation of phosphorylation at AR-binding sites.PMID:37716981 | DOI:10.1186/s40001-023-01302-4
Source: Cell Research - September 16, 2023 Category: Cytology Authors: Xu Li Yeling Tang Pengchen Liang Miaomiao Sun Tian Li Zhiping Shen Shuang Sha Source Type: research

Luteolin inhibits A549 cells proliferation and migration by down-regulating androgen receptors
ConclusionIn this study, we have explored luteolin as one of the active components of YQG, and may inhibit the proliferation and migration of A549 cells by decreasing the expression of AR and the regulation of phosphorylation at AR-binding sites.
Source: European Journal of Medical Research - September 16, 2023 Category: Research Source Type: research

Hedyotis Diffusa-Scutellaria Barbata inhibits Breast Cancer Ethyl Acetate Fraction from Hedyotis Diffusa Plus Scutellaria Barbata inhibits the Progression of Breast Cancer via Targeting LMO1 and AKT/Mtor Signaling Pathway
CONCLUSION: In conclusion, the SH herb pair inhibited the proliferation and metastasis through downregulating LMO1 expression and reducing the activation of the AKT/mTOR signaling pathway. LMO1 has the potential as a new target in the treatment of breast cancer.PMID:37711008 | DOI:10.2174/1386207326666230913105858
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Zhiyuan Li Jingwei Li Xiaofei Liu Ziyuan Sun Xiaohui Sun Source Type: research

Traditional uses, phytochemistry, pharmacology, and toxicology of the genus Artemisia L. (Asteraceae): A high-value medicinal plant
Curr Top Med Chem. 2023 Sep 14. doi: 10.2174/1568026623666230914104141. Online ahead of print.ABSTRACTBiologically active secondary metabolites, essential oils, and volatile compounds derived from medicinal and aromatic plants play a crucial role in promoting human health. Within the large family Asteraceae, the genus Artemisia consists of approximately 500 species. Artemisia species have a rich history in traditional medicine worldwide, offering remedies for a wide range of ailments, such as malaria, jaundice, toothache, gastrointestinal problems, wounds, inflammatory diseases, diarrhoea, menstrual pains, skin disorders, ...
Source: Current Topics in Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Manzoor Hussain Rakesh Kr Thakur Jabeena Khazir Sajad Ahmed Mohammad Imtiyaj Khan Praveen Rahi Latif Ahmad Peer V S Pragadheesh Satwinderjeet Kaur S N Raina Zafar Ahmad Reshi Deepmala Sehgal Vijay Rani Rajpal Bilal Ahmad Mir Source Type: research

Mentha pulegium: A Plant With Several Medicinal Properties
Endocr Metab Immune Disord Drug Targets. 2023 Sep 14. doi: 10.2174/1871530323666230914103731. Online ahead of print.ABSTRACTThe species Mentha pulegium L. (M. pulegium L.) belongs to the family Lamiaceae, native to Europe, North Africa, and the Middle East, and the genus Mentha. It has been traditionally used in food, cosmetics, and medicines. It is a perennial, fragrant, well-liked, herbaceous plant that can grow up to half a meter tall. It is extensively used as a food flavoring, particularly for Moroccan traditional drinks. Chewing mint and M. pulegium, a relaxing and refreshing plant, can be used to treat hiccups and a...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 15, 2023 Category: Endocrinology Authors: Smail Amtaghri Miloudia Slaoui Mohamed Eddouks Source Type: research

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