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Chinese Herbal Medicine for the Treatment of Adult Viral Myocarditis: An Overview of Systematic Reviews and Meta-Analyses of Randomized Controlled Trials
The objective of this study was to conduct a comprehensive overview of systematic reviews and meta-analyses of randomized controlled trials (RCTs) regarding the efficacy and safety of CHM for AVM.METHODS: A comprehensive systematic search was conducted across 8 electronic databases from their inception to June 23, 2022, augmented by manual searches of the gray literature. Systematic reviews were independently selected and data extracted in accordance with predetermined criteria by 2 reviewers. Included systematic reviews were assessed for methodologic and reporting quality using Assessing the Methodological Quality of Syst...
Source: Clinical Therapeutics - September 10, 2023 Category: Drugs & Pharmacology Authors: Xiao-Shan Hui Shi-Qi Wang Shi-Chao Lu Yong-Mei Liu Zhen-Peng Zhang Wen-Jing Lian Si-Yuan Zhou Hui Zhang Jin-Sheng Zhang Jie Wang Source Type: research
Anti-inflammatory compounds from the rhizome of < em > Acorus calamus var. angustatus Besser < /em > and their mechanism
Nat Prod Res. 2023 Sep 9:1-7. doi: 10.1080/14786419.2023.2255919. Online ahead of print.ABSTRACTSeven compounds, named β-sitosterol (1), daucosterol (2), (+)-pinoresinol-β-D-glucoside (3), (-)-syringaresinol 4-O-β-D-apiofuranosyl-(1→2)- β-D-glucopyranoside (4), 4-hydroxybenzoic acid (5), 2-(3', 4'-dihydroxyphenyl)-1, 3-pepper ring-5-aldehyde (6) and spinosin (7) were isolated from the rhizome of Acorus calamus var. angustatus Besser. 3, 4, 6 and 7 were isolated from this medicinal plant for the first time. Structures were elucidated by physicochemical properties and extensive spectroscopic analysis, as well as by com...
Source: Natural Product Research - September 9, 2023 Category: Biochemistry Authors: Liping Huang Zhenying Feng Jie Xiang Minzhen Deng Zhongliu Zhou Source Type: research
Evaluation of the anticancer activity of < em > Origanum Marjoram < /em > as a safe natural drink for daily use
CONCLUSION: Thus, the reduced apoptotic rate of MCF-7 breast cancer cells in this work was correlated to the potential anticancer effect of OMAE which would be a suitable preventable drink against cancer.PMID:37688795 | DOI:10.1080/03639045.2023.2257796
Source: Cancer Control - September 9, 2023 Category: Cancer & Oncology Authors: Ahmed A H Abdellatif Mansour Alsharidah Source Type: research
Herbal Medicine Nanocrystals: A Potential Novel Therapeutic Strategy
In conclusion, we have deliberated regarding the hurdles and forthcoming outlook in the realm of nanotoxicity, in vivo kinetics, herbal ingredients as stabilizers of nanocrystals, and the potential for surmounting drug resistance through the utilization of nanocrystalline formulations in herbal medicine. We anticipate that this review will offer innovative insights into the development of herbal medicine nanocrystals as a promising and novel therapeutic strategy.PMID:37687199 | DOI:10.3390/molecules28176370
Source: Cancer Control - September 9, 2023 Category: Cancer & Oncology Authors: Mengran Guo Shugang Qin Shiyan Wang Min Sun Huiling Yang Xinchun Wang Ping Fan Zhaohui Jin Source Type: research
Uncovering the anti-obesity constituents in Ginkgo biloba extract and deciphering their synergistic effects
This study demonstrated a case study for uncovering the anti-obesity constituents in an anti-obesity herbal medicine (Ginkgo biloba extract) and deciphering their synergistic effects via targeting human pancreatic lipase (hPL). Following screening the anti-hPL effects of eighty herbal medicines, Ginkgo biloba extract (GBE50) was found with the most potent anti-hPL activity. Global chemical profiling of herbal constituents coupling with hPL inhibition assay revealed that the bioflavonoids and several flavonoids in GBE50 were key anti-hPL constituents. Among all tested thirty-eight constituents, sciadopitysin, bilobetin, que...
Source: Fitoterapia - September 8, 2023 Category: Biochemistry Authors: Min Zhang Xu-Dong Hou Wei Liu Lu Wang Mei-Fang Jiang Jie Hou Hui Tang Guang-Bo Ge Source Type: research
Terpenoids in Diabetic nephropathy: Advances and Therapeutic Opportunities
Endocr Metab Immune Disord Drug Targets. 2023 Sep 1. doi: 10.2174/1871530323666230901164219. Online ahead of print.ABSTRACTDiabetic nephropathy (DN) is the foremost ailment resulting in end-stage renal damage. Chronic hyperglycaemia and hyperlipidaemia are the foremost reason for disease progression. The disease is characterized by the severity of albuminuria and cardiovascular disorders. Approximately 20 to 40% of the global prevalence of DN is mostly reported to occur in individuals with diabetes, and nearly 28% of DN occurs in individuals with other renal disorders. The pathological mechanism is very complex, involving ...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 8, 2023 Category: Endocrinology Authors: Manish Kaushik Aditi Kaushik Jasmine Chaudhary Akash Jain Source Type: research
Opportunities and challenges for ribosome-inactivating proteins in traditional Chinese medicine plants
Toxicon. 2023 Sep 6:107278. doi: 10.1016/j.toxicon.2023.107278. Online ahead of print.ABSTRACTRibosome-inactivating proteins (RIPs) are a class of cytotoxic rRNA N-glycosylase, which widely exist in higher plants in different taxonomy, including many traditional Chinese medicinal materials and vegetables and fruits. In this paper, the traditional Chinese medicinal plants containing RIPs protein were sorted out, and their pharmacological effects and clinical applications were analyzed. Since many RIPs in traditional Chinese medicine plants exhibit antiviral and antitumor activities and show great clinical application potent...
Source: Toxicon - September 8, 2023 Category: Toxicology Authors: Yi-Xuan Yang Xin-Yi Wang Tong Lin Yu Sun Yi-Cheng Yu Zhen-Hong Zhu Source Type: research
Terpenoids in Diabetic nephropathy: Advances and Therapeutic Opportunities
Endocr Metab Immune Disord Drug Targets. 2023 Sep 1. doi: 10.2174/1871530323666230901164219. Online ahead of print.ABSTRACTDiabetic nephropathy (DN) is the foremost ailment resulting in end-stage renal damage. Chronic hyperglycaemia and hyperlipidaemia are the foremost reason for disease progression. The disease is characterized by the severity of albuminuria and cardiovascular disorders. Approximately 20 to 40% of the global prevalence of DN is mostly reported to occur in individuals with diabetes, and nearly 28% of DN occurs in individuals with other renal disorders. The pathological mechanism is very complex, involving ...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 8, 2023 Category: Endocrinology Authors: Manish Kaushik Aditi Kaushik Jasmine Chaudhary Akash Jain Source Type: research
Opportunities and challenges for ribosome-inactivating proteins in traditional Chinese medicine plants
Toxicon. 2023 Sep 6:107278. doi: 10.1016/j.toxicon.2023.107278. Online ahead of print.ABSTRACTRibosome-inactivating proteins (RIPs) are a class of cytotoxic rRNA N-glycosylase, which widely exist in higher plants in different taxonomy, including many traditional Chinese medicinal materials and vegetables and fruits. In this paper, the traditional Chinese medicinal plants containing RIPs protein were sorted out, and their pharmacological effects and clinical applications were analyzed. Since many RIPs in traditional Chinese medicine plants exhibit antiviral and antitumor activities and show great clinical application potent...
Source: Toxicon - September 8, 2023 Category: Toxicology Authors: Yi-Xuan Yang Xin-Yi Wang Tong Lin Yu Sun Yi-Cheng Yu Zhen-Hong Zhu Source Type: research
Uncovering the anti-obesity constituents in Ginkgo biloba extract and deciphering their synergistic effects
This study demonstrated a case study for uncovering the anti-obesity constituents in an anti-obesity herbal medicine (Ginkgo biloba extract) and deciphering their synergistic effects via targeting human pancreatic lipase (hPL). Following screening the anti-hPL effects of eighty herbal medicines, Ginkgo biloba extract (GBE50) was found with the most potent anti-hPL activity. Global chemical profiling of herbal constituents coupling with hPL inhibition assay revealed that the bioflavonoids and several flavonoids in GBE50 were key anti-hPL constituents. Among all tested thirty-eight constituents, sciadopitysin, bilobetin, que...
Source: Fitoterapia - September 8, 2023 Category: Biochemistry Authors: Min Zhang Xu-Dong Hou Wei Liu Lu Wang Mei-Fang Jiang Jie Hou Hui Tang Guang-Bo Ge Source Type: research
Terpenoids in Diabetic nephropathy: Advances and Therapeutic Opportunities
Endocr Metab Immune Disord Drug Targets. 2023 Sep 1. doi: 10.2174/1871530323666230901164219. Online ahead of print.ABSTRACTDiabetic nephropathy (DN) is the foremost ailment resulting in end-stage renal damage. Chronic hyperglycaemia and hyperlipidaemia are the foremost reason for disease progression. The disease is characterized by the severity of albuminuria and cardiovascular disorders. Approximately 20 to 40% of the global prevalence of DN is mostly reported to occur in individuals with diabetes, and nearly 28% of DN occurs in individuals with other renal disorders. The pathological mechanism is very complex, involving ...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 8, 2023 Category: Drugs & Pharmacology Authors: Manish Kaushik Aditi Kaushik Jasmine Chaudhary Akash Jain Source Type: research
Uncovering the anti-obesity constituents in Ginkgo biloba extract and deciphering their synergistic effects
This study demonstrated a case study for uncovering the anti-obesity constituents in an anti-obesity herbal medicine (Ginkgo biloba extract) and deciphering their synergistic effects via targeting human pancreatic lipase (hPL). Following screening the anti-hPL effects of eighty herbal medicines, Ginkgo biloba extract (GBE50) was found with the most potent anti-hPL activity. Global chemical profiling of herbal constituents coupling with hPL inhibition assay revealed that the bioflavonoids and several flavonoids in GBE50 were key anti-hPL constituents. Among all tested thirty-eight constituents, sciadopitysin, bilobetin, que...
Source: Fitoterapia - September 8, 2023 Category: Biochemistry Authors: Min Zhang Xu-Dong Hou Wei Liu Lu Wang Mei-Fang Jiang Jie Hou Hui Tang Guang-Bo Ge Source Type: research
Terpenoids in Diabetic nephropathy: Advances and Therapeutic Opportunities
Endocr Metab Immune Disord Drug Targets. 2023 Sep 1. doi: 10.2174/1871530323666230901164219. Online ahead of print.ABSTRACTDiabetic nephropathy (DN) is the foremost ailment resulting in end-stage renal damage. Chronic hyperglycaemia and hyperlipidaemia are the foremost reason for disease progression. The disease is characterized by the severity of albuminuria and cardiovascular disorders. Approximately 20 to 40% of the global prevalence of DN is mostly reported to occur in individuals with diabetes, and nearly 28% of DN occurs in individuals with other renal disorders. The pathological mechanism is very complex, involving ...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 8, 2023 Category: Drugs & Pharmacology Authors: Manish Kaushik Aditi Kaushik Jasmine Chaudhary Akash Jain Source Type: research
Opportunities and challenges for ribosome-inactivating proteins in traditional Chinese medicine plants
Toxicon. 2023 Sep 6:107278. doi: 10.1016/j.toxicon.2023.107278. Online ahead of print.ABSTRACTRibosome-inactivating proteins (RIPs) are a class of cytotoxic rRNA N-glycosylase, which widely exist in higher plants in different taxonomy, including many traditional Chinese medicinal materials and vegetables and fruits. In this paper, the traditional Chinese medicinal plants containing RIPs protein were sorted out, and their pharmacological effects and clinical applications were analyzed. Since many RIPs in traditional Chinese medicine plants exhibit antiviral and antitumor activities and show great clinical application potent...
Source: Toxicon - September 8, 2023 Category: Toxicology Authors: Yi-Xuan Yang Xin-Yi Wang Tong Lin Yu Sun Yi-Cheng Yu Zhen-Hong Zhu Source Type: research
