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< em > Moringa oleifera < /em > : A Review on the Antiproliferative Potential in Breast Cancer Cells
Curr Issues Mol Biol. 2023 Aug 18;45(8):6880-6902. doi: 10.3390/cimb45080434.ABSTRACTThe global burden of female breast cancer and associated deaths has become a major concern. Many chemotherapeutic agents, such as doxorubicin, have been shown to have adverse side effects. The development of multi-drug resistance is a common occurrence, contributing to chemotherapeutic failure. The resistance of breast cancer cells to drug treatment leads to a decline in the treatment efficacy and an increase in cancer recurrence. Therefore, action is required to produce alternative drug therapies, such as herbal drugs. Herbal drugs have b...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Malebogo M Moremane Beynon Abrahams Charlette Tiloke Source Type: research
The Effect of the Mixed Extract of < em > Kalopanax pictus < /em > Nakai and < em > Achyranthes japonica < /em > Nakai on the Improvement of Degenerative Osteoarthritis through Inflammation Inhibition in the Monosodium Iodoacetate-Induced Mouse Model
The objective of this study is to confirm the potential of a mixture extract of Kalopanax pictus Nakai and Achyranthes japonica Nakai as a functional raw material for improving osteoarthritis through anti-inflammatory effects in macrophages and MIA-induced arthritis experimental animals. In macrophages inflamed by lipopolysaccharide (LPS), treatment of Kalopanax pictus Nakai and Achyranthes japonica Nakai mixture inhibits NF-κB and mitogen-activated protein kinase (MAPK) activities, thereby inhibiting inflammatory cytokine tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6), inflammatory factors PGE2, MMP-2, and...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Hak-Yong Lee Young-Mi Park Hai-Min Hwang Dong-Yeop Shin Han-Na Jeong Jae-Gon Kim Hyo-Yeon Park Dae-Sung Kim Jin-Joo Yoo Myung-Sunny Kim Min-Jung Kim Hye-Jeong Yang Soo-Cheol Choi In-Ah Lee Source Type: research
< em > Moringa oleifera < /em > : A Review on the Antiproliferative Potential in Breast Cancer Cells
Curr Issues Mol Biol. 2023 Aug 18;45(8):6880-6902. doi: 10.3390/cimb45080434.ABSTRACTThe global burden of female breast cancer and associated deaths has become a major concern. Many chemotherapeutic agents, such as doxorubicin, have been shown to have adverse side effects. The development of multi-drug resistance is a common occurrence, contributing to chemotherapeutic failure. The resistance of breast cancer cells to drug treatment leads to a decline in the treatment efficacy and an increase in cancer recurrence. Therefore, action is required to produce alternative drug therapies, such as herbal drugs. Herbal drugs have b...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Malebogo M Moremane Beynon Abrahams Charlette Tiloke Source Type: research
The Effect of the Mixed Extract of < em > Kalopanax pictus < /em > Nakai and < em > Achyranthes japonica < /em > Nakai on the Improvement of Degenerative Osteoarthritis through Inflammation Inhibition in the Monosodium Iodoacetate-Induced Mouse Model
The objective of this study is to confirm the potential of a mixture extract of Kalopanax pictus Nakai and Achyranthes japonica Nakai as a functional raw material for improving osteoarthritis through anti-inflammatory effects in macrophages and MIA-induced arthritis experimental animals. In macrophages inflamed by lipopolysaccharide (LPS), treatment of Kalopanax pictus Nakai and Achyranthes japonica Nakai mixture inhibits NF-κB and mitogen-activated protein kinase (MAPK) activities, thereby inhibiting inflammatory cytokine tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6), inflammatory factors PGE2, MMP-2, and...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Hak-Yong Lee Young-Mi Park Hai-Min Hwang Dong-Yeop Shin Han-Na Jeong Jae-Gon Kim Hyo-Yeon Park Dae-Sung Kim Jin-Joo Yoo Myung-Sunny Kim Min-Jung Kim Hye-Jeong Yang Soo-Cheol Choi In-Ah Lee Source Type: research
< em > Moringa oleifera < /em > : A Review on the Antiproliferative Potential in Breast Cancer Cells
Curr Issues Mol Biol. 2023 Aug 18;45(8):6880-6902. doi: 10.3390/cimb45080434.ABSTRACTThe global burden of female breast cancer and associated deaths has become a major concern. Many chemotherapeutic agents, such as doxorubicin, have been shown to have adverse side effects. The development of multi-drug resistance is a common occurrence, contributing to chemotherapeutic failure. The resistance of breast cancer cells to drug treatment leads to a decline in the treatment efficacy and an increase in cancer recurrence. Therefore, action is required to produce alternative drug therapies, such as herbal drugs. Herbal drugs have b...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Malebogo M Moremane Beynon Abrahams Charlette Tiloke Source Type: research
The Effect of the Mixed Extract of < em > Kalopanax pictus < /em > Nakai and < em > Achyranthes japonica < /em > Nakai on the Improvement of Degenerative Osteoarthritis through Inflammation Inhibition in the Monosodium Iodoacetate-Induced Mouse Model
The objective of this study is to confirm the potential of a mixture extract of Kalopanax pictus Nakai and Achyranthes japonica Nakai as a functional raw material for improving osteoarthritis through anti-inflammatory effects in macrophages and MIA-induced arthritis experimental animals. In macrophages inflamed by lipopolysaccharide (LPS), treatment of Kalopanax pictus Nakai and Achyranthes japonica Nakai mixture inhibits NF-κB and mitogen-activated protein kinase (MAPK) activities, thereby inhibiting inflammatory cytokine tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6), inflammatory factors PGE2, MMP-2, and...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Hak-Yong Lee Young-Mi Park Hai-Min Hwang Dong-Yeop Shin Han-Na Jeong Jae-Gon Kim Hyo-Yeon Park Dae-Sung Kim Jin-Joo Yoo Myung-Sunny Kim Min-Jung Kim Hye-Jeong Yang Soo-Cheol Choi In-Ah Lee Source Type: research
< em > Moringa oleifera < /em > : A Review on the Antiproliferative Potential in Breast Cancer Cells
Curr Issues Mol Biol. 2023 Aug 18;45(8):6880-6902. doi: 10.3390/cimb45080434.ABSTRACTThe global burden of female breast cancer and associated deaths has become a major concern. Many chemotherapeutic agents, such as doxorubicin, have been shown to have adverse side effects. The development of multi-drug resistance is a common occurrence, contributing to chemotherapeutic failure. The resistance of breast cancer cells to drug treatment leads to a decline in the treatment efficacy and an increase in cancer recurrence. Therefore, action is required to produce alternative drug therapies, such as herbal drugs. Herbal drugs have b...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Malebogo M Moremane Beynon Abrahams Charlette Tiloke Source Type: research
The Effect of the Mixed Extract of < em > Kalopanax pictus < /em > Nakai and < em > Achyranthes japonica < /em > Nakai on the Improvement of Degenerative Osteoarthritis through Inflammation Inhibition in the Monosodium Iodoacetate-Induced Mouse Model
The objective of this study is to confirm the potential of a mixture extract of Kalopanax pictus Nakai and Achyranthes japonica Nakai as a functional raw material for improving osteoarthritis through anti-inflammatory effects in macrophages and MIA-induced arthritis experimental animals. In macrophages inflamed by lipopolysaccharide (LPS), treatment of Kalopanax pictus Nakai and Achyranthes japonica Nakai mixture inhibits NF-κB and mitogen-activated protein kinase (MAPK) activities, thereby inhibiting inflammatory cytokine tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6), inflammatory factors PGE2, MMP-2, and...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Hak-Yong Lee Young-Mi Park Hai-Min Hwang Dong-Yeop Shin Han-Na Jeong Jae-Gon Kim Hyo-Yeon Park Dae-Sung Kim Jin-Joo Yoo Myung-Sunny Kim Min-Jung Kim Hye-Jeong Yang Soo-Cheol Choi In-Ah Lee Source Type: research
< em > Moringa oleifera < /em > : A Review on the Antiproliferative Potential in Breast Cancer Cells
Curr Issues Mol Biol. 2023 Aug 18;45(8):6880-6902. doi: 10.3390/cimb45080434.ABSTRACTThe global burden of female breast cancer and associated deaths has become a major concern. Many chemotherapeutic agents, such as doxorubicin, have been shown to have adverse side effects. The development of multi-drug resistance is a common occurrence, contributing to chemotherapeutic failure. The resistance of breast cancer cells to drug treatment leads to a decline in the treatment efficacy and an increase in cancer recurrence. Therefore, action is required to produce alternative drug therapies, such as herbal drugs. Herbal drugs have b...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Malebogo M Moremane Beynon Abrahams Charlette Tiloke Source Type: research
