Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE < sup > -/- < /sup > mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis

CONCLUSION: Our findings suggest that ZCHP can effectively attenuate AS progression by inhibiting MAPK/ERK signaling-mediated apoptosis via FGFR3 hypermethylation in the promoter region.PMID:37716492 | DOI:10.1016/j.jep.2023.117188

Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Yan Zhang Dandan Li Zijun Jia Jun Mei Ya Wang Ying Zhang Qingbing Zhou Fengqin Xu Source Type: research