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Vaccination: Influenza Vaccine
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Total 6499 results found since Jan 2013.
The Adenylyl Cyclase Activator Forskolin Increases Influenza Virus Propagation in MDCK Cells by Regulating ERK1/2 Activity
In this study, we investigated whether treatment with forskolin (FSK), an adenylyl cyclase activator, affected the output of a cell-based influenza vaccine. We found that FSK increased the propagation of three influenza virus subtypes (A/H1N1/California/4/09, A/H3N2/Mississippi/1/85, and B/Shandong/7/97) in Madin-Darby canine kidney (MDCK) cells. Interestingly, FSK suppressed the growth of MDCK cells. This effect could be a result of protein kinase A (PKA)-Src axis activation, which downregulates extracellular signal-regulated kinase (ERK)1/2 activity and delays cell cycle progression from G1 to S. This delay in cell growt...
Source: Journal of Microbiology and Biotechnology - August 30, 2023 Category: Biotechnology Authors: Sang-Yeon Lee Jisun Lee Hye-Lim Park Yong-Wook Park Hun Kim Jae-Hwan Nam Source Type: research
Knowledge, attitudes, concern, behaviors, and barriers associated with the readiness to receive seasonal influenza vaccine among healthcare workers in oncology setting during the COVID-19 pandemic
This study examines the knowledge, attitudes, concerns, behaviors, and barriers related to seasonal influenza vaccination among healthcare workers (HCWs) in the oncology setting during the COVID-19 pandemic. The objective is to assess the readiness of HCWs to receive the influenza vaccine. A cross-sectional study was conducted at the King Hussein Cancer Center (KHCC) in Amman, Jordan. HCWs were surveyed using a self-administered web-based questionnaire between October 2021 and November 2021. Among 223 participants, the coverage rates for seasonal influenza vaccination ranged from 65% to 81% during the autumns of 2019 and 2...
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Sawsan Mubarak Hadeel AlGhawrie Bayan Qaddumi Source Type: research
The potential cost-effectiveness of next generation influenza vaccines in England and Wales: A modelling analysis
Vaccine. 2023 Aug 24:S0264-410X(23)00963-5. doi: 10.1016/j.vaccine.2023.08.031. Online ahead of print.ABSTRACTNext generation influenza vaccines are in development and have the potential for widespread health and economic benefits. Determining the potential health and economic impact for these vaccines is needed to drive investment in bringing these vaccines to the market, and to inform which groups public health policies on influenza vaccination should target. We used a mathematical modelling approach to estimate the epidemiological impact and cost-effectiveness of next generation influenza vaccines in England and Wales. ...
Source: Vaccine - August 26, 2023 Category: Allergy & Immunology Authors: Naomi R Waterlow Simon R Procter Edwin van Leeuwen Sreejith Radhakrishnan Mark Jit Rosalind M Eggo Source Type: research
Exploring missed opportunities for influenza vaccination and influenza vaccine co-administration patterns among Italian older adults: a retrospective cohort study
CONCLUSIONS: A sizeable proportion of older adults who received other recommended vaccines during the last influenza season did not receive SIV. This share of missed opportunities, which are subject to some social inequalities, may be addressed by increasing vaccine co-administration rates and implementing tailored health promotion interventions.PMID:37632235 | DOI:10.1093/eurpub/ckad155
Source: Herpes - August 26, 2023 Category: Infectious Diseases Authors: Alexander Domnich Andrea Orsi Matilde Ogliastro Carlo-Simone Trombetta Marianna Scarpaleggia Chiara Ceccaroli Carla Amadio Anna Raffo Luca Berisso Alla Yakubovich Giacomo Zappa Daniela Amicizia Donatella Panatto Giancarlo Icardi Source Type: research
TWiV 1038: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses modeling poliovirus transmission and responses in New York State, FDA approves first vaccine for pregnant individuals to prevent RSV in infants, prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices, Nirmatrelvir resistance – de novo E166V/L50V mutations in an immunocompromised patient treated with prolonged nirmatrelvir/ritonavir monotherapy leading to clinical and virological treatment failure, incidence of new-onset hypertension post–COVID-19: comparison with influenza, and post-acute sequel...
Source: This Week in Virology - MP3 Edition - August 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Age-specific severity of severe acute respiratory syndrome coronavirus 2 in February 2020 to June 2021 in the Netherlands
CONCLUSION: Whereas the increase in severity of Severe Acute Respiratory Syndrome Coronavirus 2 with age remained stable, the risk of death upon infection decreased over time. A significant drop in risk of death among elderly coincided with the introduction of COVID-19 vaccination.PMID:37621921 | PMC:PMC10444602 | DOI:10.1111/irv.13174
Source: Respiratory Care - August 25, 2023 Category: Respiratory Medicine Authors: Pieter T de Boer Jan van de Kassteele Eric R A Vos Liselotte van Asten Dave A Dongelmans Arianne B van Gageldonk-Lafeber Gerco den Hartog Agnetha Hofhuis Fiona van der Klis Dylan W de Lange Lenny Stoeldraijer RIVM COVID ‐19 epidemiology and surveillance Source Type: research
Interspecies Transmission of Swine Influenza A Viruses and Human Seasonal Vaccine-Mediated Protection Investigated in Ferret Model
Emerg Infect Dis. 2023 Sep;29(9):1798-1807. doi: 10.3201/eid2909.230066.ABSTRACTWe investigated the infection dynamics of 2 influenza A(H1N1) virus isolates from the swine 1A.3.3.2 (pandemic 2009) and 1C (Eurasian, avian-like) lineages. The 1C-lineage virus, A/Pavia/65/2016, although phylogenetically related to swine-origin viruses, was isolated from a human clinical case. This strain infected ferrets, a human influenza model species, and could be transmitted by direct contact and, less efficiently, by airborne exposure. Infecting ferrets and pigs (the natural host) resulted in mild or inapparent clinical signs comparable ...
Source: Emerging Infectious Diseases - August 23, 2023 Category: Infectious Diseases Authors: Pauline M van Diemen Alexander M P Byrne Andrew M Ramsay Samantha Watson Alejandro Nunez Ana V Moreno Chiara Chiapponi Emanuela Foni Ian H Brown Sharon M Brookes Helen E Everett Source Type: research
The Possible Mechanisms of Cu and Zn in the Treatment and Prevention of HIV and COVID-19 Viral Infection
Biol Trace Elem Res. 2023 Aug 23. doi: 10.1007/s12011-023-03788-9. Online ahead of print.ABSTRACTDue to their unique properties and their potential therapeutic and prophylactic applications, heavy metals have attracted the interest of many researchers, especially during the outbreak of COVID-19. Indeed, zinc (Zn) and copper (Cu) have been widely used during viral infections. Zn has been reported to prevent excessive inflammatory response and cytokine storm, improve the response of the virus to Type I interferon (IFN-1), and enhance the production of IFN-a to counteract the antagonistic effect of SARS-CoV-2 virus protein on...
Source: Biological Trace Element Research - August 22, 2023 Category: Biology Authors: Shatha A Albalawi Raneem A Albalawi Amaal A Albalawi Raghad F Alanazi Raghad M Almahlawi Basma S Alhwity Bashayer D Alatawi Nehal Elsherbiny Saleh F Alqifari Mohamed S Abdel-Maksoud Source Type: research
Increasing Influenza vaccination uptake rates in the 65-year-old population
Ir Med J. 2023 Aug 17;116(7):805.NO ABSTRACTPMID:37606210
Source: Ir Med J - August 22, 2023 Category: General Medicine Source Type: research
The Possible Mechanisms of Cu and Zn in the Treatment and Prevention of HIV and COVID-19 Viral Infection
Biol Trace Elem Res. 2023 Aug 23. doi: 10.1007/s12011-023-03788-9. Online ahead of print.ABSTRACTDue to their unique properties and their potential therapeutic and prophylactic applications, heavy metals have attracted the interest of many researchers, especially during the outbreak of COVID-19. Indeed, zinc (Zn) and copper (Cu) have been widely used during viral infections. Zn has been reported to prevent excessive inflammatory response and cytokine storm, improve the response of the virus to Type I interferon (IFN-1), and enhance the production of IFN-a to counteract the antagonistic effect of SARS-CoV-2 virus protein on...
Source: Cell Research - August 22, 2023 Category: Cytology Authors: Shatha A Albalawi Raneem A Albalawi Amaal A Albalawi Raghad F Alanazi Raghad M Almahlawi Basma S Alhwity Bashayer D Alatawi Nehal Elsherbiny Saleh F Alqifari Mohamed S Abdel-Maksoud Source Type: research
