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Vaccination: Influenza Vaccine
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Total 6499 results found since Jan 2013.
Contributions of cost-effectiveness analyses (CEA) to influenza vaccination policy for older adults in Europe
Vaccine. 2023 Aug 5:S0264-410X(23)00919-2. doi: 10.1016/j.vaccine.2023.07.073. Online ahead of print.ABSTRACTThis review describes the importance of economic evaluations and real-world evidence (RWE) for the assessment of enhanced influenza vaccines for older adults in Europe. Individuals ≥65 years of age are at increased risk of severe influenza outcomes and many countries in Europe recommend enhanced vaccines for this population to mitigate immunosenescence. Some National Immunization Technical Advisory Groups (NITAGs) may preferentially recommend a specific enhanced vaccine, necessitating comparative economic evaluati...
Source: Vaccine - August 7, 2023 Category: Allergy & Immunology Authors: Annie Chicoye Pascal Cr épey Van Hung Nguyen Sergio M árquez-Peláez Maarten Postma Andrea Pugliese Jes ús Ruiz-Aragón Joaquin Mould-Quevedo Source Type: research
The Use of < em > In Silico < /em > Methods to Identify and Assess Antigenic Regions Suitable for the Development of Peptide-based Pan-viral Vaccines
We report a pan-antigenic peptide region with strong affinity for MHC-I and MHC-II, and good immunogenic potential. According to the output from the relevant in silico tools, the peptide was predicted to be non-toxic, non-allergic and to possess the desired physicochemical properties for potentially successful vaccine production. With further investigation and optimisation, this peptide could be considered for use in the development of a broad-spectrum anti-viral vaccine that may protect against emerging new viruses. Our approach of using in silico methods to identify candidate antigenic peptides with the desired physicoch...
Source: Alternatives to Laboratory Animals : ATLA - August 7, 2023 Category: Research Authors: Shayana Saravanakumar Jhinuk Chatterjee Source Type: research
Unique Changes in the Incidence of Acute Chest Syndrome in Children with Sickle-Cell Disease Unravel the Role of Respiratory Pathogens: A Time-Series Analysis
Chest. 2023 Aug 4:S0012-3692(23)05256-X. doi: 10.1016/j.chest.2023.07.4219. Online ahead of print.ABSTRACTBACKGROUND: Acute chest syndrome (ACS) is a life-threatening complication of sickle-cell disease (SCD). Although respiratory pathogens are frequently detected in children with ACS, their respective role in triggering the disease is still unclear. We hypothesized that ACS incidence followed the unprecedented population-level changes in respiratory pathogens dynamics following the COVID-19-related non-pharmaceutical interventions (NPIs).RESEARCH QUESTION: What is the respective role of respiratory pathogens in ACS epidem...
Source: Chest - August 6, 2023 Category: Respiratory Medicine Authors: Zein Assad Zaba Valtuille Alexis Rybak Florentia Kaguelidou Andrea Lazzati Emmanuelle Varon Luu-Ly Pham Lea Lenglart Albert Faye Marion Caseris Robert Cohen Corinne Levy Astrid Vabret Francois Gravey Francois Angoulvant Berengere Koehl Naim Ouldali Source Type: research
Safety profile and SARS-CoV-2 breakthrough infections among HCWs receiving anti-SARS-CoV-2 and influenza vaccines simultaneously: an Italian observational study
This study aims to evaluate the safety profile and to estimate the incidence of SARS-CoV-2 breakthrough infections in subjects receiving the anti-SARS-CoV-2 and influenza vaccines simultaneously. The study population was represented by healthcare workers (HCWs) of Bari Policlinico General Hospital who received the influenza (Flucelvax Tetra®) and/or anti-SARS-CoV-2 vaccination (BNT162b2 mRNA COVID-19 vaccine, Comirnaty®) either in coadministration or separately in October 2021. Reports of adverse events following immunization (AEFIs) were investigated to study the safety of both vaccines in coadministration and in separa...
Source: Vaccine - August 6, 2023 Category: Allergy & Immunology Authors: L Moscara V Venerito A Martinelli A Di Lorenzo F Toro F Violante S Tafuri P Stefanizzi Source Type: research
Impact of methotrexate treatment on vaccines immunogenicity in adult rheumatological patients - Lessons learned from the COVID-19 pandemic
Biomed Pharmacother. 2023 Aug 3;165:115254. doi: 10.1016/j.biopha.2023.115254. Online ahead of print.ABSTRACTDespite the development of new biological and synthetic targeted therapies, methotrexate remains one of the most commonly used immunomodulatory drugs in rheumatology. However, its effect on the immunogenicity of vaccines has been studied only to a limited extent until recently, resulting in the lack of clear guidelines on the use of methotrexate during vaccination. Significant progress was made during the COVID-19 pandemic due to the dynamic development of research on vaccines, including patients with autoimmune inf...
Source: Herpes - August 5, 2023 Category: Infectious Diseases Authors: Jakub Wro ński Marzena Ciechomska Ewa Kuca-Warnawin Source Type: research
Prediction of highly pathogenic avian influenza vaccine efficacy in chickens by comparison of in vitro and in vivo data: A meta-analysis and systematic review
Vaccine. 2023 Aug 1:S0264-410X(23)00922-2. doi: 10.1016/j.vaccine.2023.07.076. Online ahead of print.ABSTRACTVaccines for avian influenza (AI) can protect poultry against disease, mortality, and virus transmission. Numerous factors, including: vaccine platform, immunogenicity, and relatedness to the field strain, are known to be important to achieving optimal AI vaccine efficacy. To better understand how these factors contribute to vaccine protection, a systematic meta-analysis was conducted to evaluate efficacy data for vaccines in chickens challenged with highly pathogenic (HP) AI. Data from a total of 120 individual tri...
Source: Herpes - August 3, 2023 Category: Infectious Diseases Authors: Jongseo Mo Erica Spackman David E Swayne Source Type: research
Risk of Miscarriage in Relation to Seasonal Influenza Vaccination Before or During Pregnancy
CONCLUSION: Influenza vaccination before or during pregnancy was not associated with miscarriage.PMID:37535959 | DOI:10.1097/AOG.0000000000005279
Source: Obstetrics and Gynecology - August 3, 2023 Category: OBGYN Authors: Annette K Regan Amelia K Wesselink Tanran R Wang David A Savitz Jennifer J Yland Kenneth J Rothman Elizabeth E Hatch Lauren A Wise Source Type: research
Modeling the impact of vaccination for the immunization Agenda 2030: Deaths averted due to vaccination against 14 pathogens in 194 countries from 2021 to 2030
Vaccine. 2023 Aug 1:S0264-410X(23)00854-X. doi: 10.1016/j.vaccine.2023.07.033. Online ahead of print.ABSTRACTBACKGROUND: The Immunization Agenda 2030 (IA2030) Impact Goal 1.1. aims to reduce the number of future deaths averted through immunization in the next decade. To estimate the potential impact of the aspirational coverage targets for IA2030, we developed an analytical framework and estimated the number of deaths averted due to an ambitious vaccination coverage scenario from 2021 to 2030 in 194 countries.METHOD: A demographic model was used to determine annual age-specific mortality estimates associated with vaccine c...
Source: Vaccine - August 3, 2023 Category: Allergy & Immunology Authors: Austin Carter William Msemburi So Yoon Sim Katy A M Gaythorpe Philipp Lambach Ann Lindstrand Raymond Hutubessy Source Type: research
Prediction of highly pathogenic avian influenza vaccine efficacy in chickens by comparison of in vitro and in vivo data: A meta-analysis and systematic review
Vaccine. 2023 Aug 1:S0264-410X(23)00922-2. doi: 10.1016/j.vaccine.2023.07.076. Online ahead of print.ABSTRACTVaccines for avian influenza (AI) can protect poultry against disease, mortality, and virus transmission. Numerous factors, including: vaccine platform, immunogenicity, and relatedness to the field strain, are known to be important to achieving optimal AI vaccine efficacy. To better understand how these factors contribute to vaccine protection, a systematic meta-analysis was conducted to evaluate efficacy data for vaccines in chickens challenged with highly pathogenic (HP) AI. Data from a total of 120 individual tri...
Source: Vaccine - August 3, 2023 Category: Allergy & Immunology Authors: Jongseo Mo Erica Spackman David E Swayne Source Type: research
Neutralizing Antibody Responses against Five SARS-CoV-2 Variants and T Lymphocyte Change after Vaccine Breakthrough Infections from the SARS-CoV-2 Omicron BA.1 Variant in Tianjin, China: A Prospective Study
CONCLUSION: Omicron BA.1 breakthrough infection mainly evoked humoral immune memory in the original strain after vaccination and hardly produced neutralizing antibodies specific to Omicron BA.1. Neutralizing antibodies against the different strains declined rapidly and showed features similar to those of influenza. Thus, T-lymphocytes may play an important role in recovery.PMID:37533385 | DOI:10.3967/bes2023.047
Source: Biomedical and Environmental Sciences : BES - August 3, 2023 Category: Biomedical Science Authors: Ying Zhang Jiang Wen Qu Min Na Zheng Ya Xing Ding Wei Chen Shao Dong Ye Xiao Yan Li Yan Kun Li Ying Liu Di Zhu Can Rui Jin Lin Wang Jin Ye Yang Yu Zhai Er Qiang Wang Xing Meng Source Type: research
