Effect of high disease activity on spinal sagittal malalignment in patients with rheumatoid arthritis
CONCLUSIONS: Spinal sagittal alignment deteriorates over time in patients with RA. High disease activity in RA exacerbates spinal deformity.PMID:38552241 | DOI:10.3171/2024.1.SPINE231199 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - March 29, 2024 Category: Neurosurgery Authors: Shintaro Honda Koichi Murata Shunsuke Fujibayashi Bungo Otsuki Takayoshi Shimizu Takayuki Fujii Yaichiro Okuzu Toshiyuki Kawai Yutaka Kuroda Akira Onishi Kosaku Murakami Hideo Onizawa Masao Tanaka Akio Morinobu Shuichi Matsuda Source Type: research

Effect of high disease activity on spinal sagittal malalignment in patients with rheumatoid arthritis
CONCLUSIONS: Spinal sagittal alignment deteriorates over time in patients with RA. High disease activity in RA exacerbates spinal deformity.PMID:38552241 | DOI:10.3171/2024.1.SPINE231199 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - March 29, 2024 Category: Neurosurgery Authors: Shintaro Honda Koichi Murata Shunsuke Fujibayashi Bungo Otsuki Takayoshi Shimizu Takayuki Fujii Yaichiro Okuzu Toshiyuki Kawai Yutaka Kuroda Akira Onishi Kosaku Murakami Hideo Onizawa Masao Tanaka Akio Morinobu Shuichi Matsuda Source Type: research

Exploring the Mechanism of Acupuncture's Influence on the Protease Activity and Free Radical Damage in Synovial Fluid of Rheumatoid Arthritis Rats Induced by Type II Collagen from the Release of Active Oxygen
Appl Biochem Biotechnol. 2024 Mar 28. doi: 10.1007/s12010-024-04932-4. Online ahead of print.ABSTRACTAcupuncture was studied to investigate the mechanism of its effect on protease vitality and free radical damage in Type I CIA rats induced by type II collagen. The study divided rats into a control group (injected with physiological saline, n = 10), a model group (injected with type II collagen, n = 10), and an intervention group (injected with type II collagen + acupuncture ST36 and GB39, 3 times a week, for a total of 4 weeks, n = 10) based on the different injected drugs. Then, various indicators of the mice were experim...
Source: Applied Biochemistry and Biotechnology - March 28, 2024 Category: Biochemistry Authors: Kaiying Cui Dezhong Bi Fuyan Wang Pengfei Hou Jinxing Guo Zhanwang Xu Source Type: research

KLF transcription factors in bone diseases
J Cell Mol Med. 2024 Apr;28(8):e18278. doi: 10.1111/jcmm.18278.ABSTRACTKrüppel-like factors (KLFs) are crucial in the development of bone disease. They are a family of zinc finger transcription factors that are unusual in containing three highly conserved zinc finger structural domains interacting with DNA. It has been discovered that it engages in various cell functions, including proliferation, apoptosis, autophagy, stemness, invasion and migration, and is crucial for the development of human tissues. In recent years, the role of KLFs in bone physiology and pathology has received adequate attention. In addition to regul...
Source: J Cell Mol Med - March 28, 2024 Category: Molecular Biology Authors: Haixia Wang Juanjuan Han Gorbachev Dmitrii Ke Ning Xin-An Zhang Source Type: research

KLF transcription factors in bone diseases
J Cell Mol Med. 2024 Apr;28(8):e18278. doi: 10.1111/jcmm.18278.ABSTRACTKrüppel-like factors (KLFs) are crucial in the development of bone disease. They are a family of zinc finger transcription factors that are unusual in containing three highly conserved zinc finger structural domains interacting with DNA. It has been discovered that it engages in various cell functions, including proliferation, apoptosis, autophagy, stemness, invasion and migration, and is crucial for the development of human tissues. In recent years, the role of KLFs in bone physiology and pathology has received adequate attention. In addition to regul...
Source: Molecular Medicine - March 28, 2024 Category: Molecular Biology Authors: Haixia Wang Juanjuan Han Gorbachev Dmitrii Ke Ning Xin-An Zhang Source Type: research