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Condition: Heart Failure
Procedure: Perfusion

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Total 107 results found since Jan 2013.

Long ‐term prognostic value of vasodilator stress cardiac magnetic resonance in patients with atrial fibrillation
ConclusionsVasodilator stress perfusion CMR demonstrated an excellent diagnostic and significant prognostic value at long-term follow-up in high-risk patients with persistent AF and suspected or known CAD.
Source: ESC Heart Failure - December 6, 2021 Category: Cardiology Authors: Karl J. Weiss, Sarah B. Nasser, Tamar Bigvava, Adelina Doltra, Bernhard Schnackenburg, Alexander Berger, Markus S. Anker, Christian Stehning, Patrick Doeblin, Mohamed Abdelmeguid, Mohamed Talat, Rolf Gebker, Wael E ‐Naggar, Burkert Pieske, Tags: Original Article Source Type: research

Diabetes and Heart Failure: Multi-Omics Approaches
This article reviewed the recent omics-driven discoveries in the diagnosis and treatment of type 2 diabetes and heart failure with focus on the common molecular mechanisms.
Source: Frontiers in Physiology - August 6, 2021 Category: Physiology Source Type: research

Mildly Increased Renin Expression in the Absence of Kidney Injury in the Murine Transverse Aortic Constriction Model
Cardiorenal syndrome type 2 is characterized by kidney failure as a consequence of heart failure that affects >50% of heart failure patients. Murine transverse aortic constriction (TAC) is a heart failure model, where pressure overload is induced on the heart without any systemic hypertension or its consequences. Whether renal function is altered in this model is debated, and if so, at which time post-TAC renal dysfunction starts to contribute to worsening of cardiac function. We therefore studied the effects of progressive heart failure development on kidney function in the absence of chronically elevated systemic bloo...
Source: Frontiers in Pharmacology - June 15, 2021 Category: Drugs & Pharmacology Source Type: research

Combined brain/heart magnetic resonance imaging in antiphospholipid syndrome-two sides of the same coin
AbstractAntiphospholipid syndrome (APS) is an autoimmune disorder characterized by arterial, venous, and/or small vessel thrombosis, pregnancy morbidity, and persistently elevated levels of antiphospholipid antibodies (aPL). Cardiovascular disease (CVD) in APS can present as heart valvular disease (HVD), macro-micro-coronary artery disease (CAD), myocardial dysfunction, cardiac thrombi, or pulmonary hypertension. Brain disease presents as stroke or transient ischemic attack (TIA) and less frequently as cerebral venous thrombosis, seizures, cognitive dysfunction, multiple sclerosis (MS) −like syndrome, or chorea. Infarcts...
Source: Clinical Rheumatology - June 10, 2021 Category: Rheumatology Source Type: research

In-vitro modeling of micro-emboli and their effect on microvascular circulation and endothelium mechanics
The objective of our study was to model embolization in microvasculature on a chip and study the biomechanical response.Methods: we used two cellular types, the established Human Umbilical Vein Endothelial Cells (HUVEC) and lung-specific Human Pulmonary Artery Endothelial Cells (HPAEC) to create self-organized microvasculature in microfluidics chips. We diluted carboxylated micro-beads (~5 mm) perfusing them with a controlled pressure head, visualizing flow in real-time with nano-tracers of distinct fluorescence. We perfused them sequentially, before and after embolization, during a 3D confocal image acquisition, while acq...
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Piccari, L., Malandrino, A., Rodriguez, D. A., Sharpe, J. Tags: Pulmonary embolism Source Type: research

Left ventricular concentric remodeling and impaired cardiorespiratory fitness in patients with heart failure and preserved ejection fraction.
CONCLUSIONS: Post-exercise reduced LV volumes correlate with measures of impaired CRF in patients with HFpEF, thus supporting a pathophysiologic role of concentric remodeling in impaired CRF in HFpEF. PMID: 32996304 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - October 2, 2020 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Hemodynamic effects of ivabradine use in combination with intravenous inotropic therapy in advanced heart failure
AbstractIntravenous inotropic therapy can be used in patients with advanced heart failure, as palliative therapy or as a bridge to cardiac transplantation or mechanical circulatory support, as well as in cardiogenic shock. Their use is limited to increasing cardiac output in low cardiac output states and reducing ventricular filling pressures to alleviate patient symptoms and improve functional class. Many advanced heart failure patients have sinus tachycardia as a compensatory mechanism to maintain cardiac output. However, excessive sinus tachycardia caused by intravenous inotropes can increase myocardial oxygen consumpti...
Source: Heart Failure Reviews - September 29, 2020 Category: Cardiology Source Type: research

Prognostic value of myocardial perfusion imaging with D-SPECT camera in patients with ischemia and no obstructive coronary artery disease (INOCA)
ConclusionsD-SPECT MPI provides excellent prognostic information, with a more severe prognosis in patients with abnormal D-SPECT MPI. INOCA patients with abnormal D-SPECT MPI experience a poor prognosis similar to that of patients with obstructive CAD.
Source: Journal of Nuclear Cardiology - September 29, 2020 Category: Nuclear Medicine Source Type: research

Computed tomography perfusion in patients of stroke with left ventricular assist device
AbstractLeft ventricular assist devices (LVAD) are widely applied for patients with severe heart failure as a bridge to heart transplantation as well as destination therapy. Patients with implanted LVAD have an increased risk of cerebral thrombosis and computed tomographic perfusion (CTP) has the potential to be performed for early diagnosis and treatment of acute ischemic stroke (AIS), including interventional thrombectomy. Here, we report our series of CTP examination in patients having suspected AIS after LVAD implantation. We retrospectively investigated 33 contrast-enhanced CTPs from January 2017 to December 2018 whic...
Source: Heart and Vessels - August 9, 2020 Category: Cardiology Source Type: research

Cuba's Role in International Atomic Energy Agency Regional Cooperation in Cardiology.
Authors: Peix A, García B Abstract Cardiovascular diseases are the leading cause of death worldwide, and a health problem in low- and middle-income as well as high-income countries. They also constitute the main cause of death in Latin America, with ischemic heart disease as the principal cause in most countries of the region. In Cuba, heart disease is the first cause of death, followed by cancer and stroke. In its 2030 Agenda for Sustainable Development, the UN recognizes the importance of chronic non-communicable diseases, including cardiovascular diseases. Cuba has participated actively as lead partner in desig...
Source: MEDICC Review - April 28, 2020 Category: International Medicine & Public Health Tags: MEDICC Rev Source Type: research

Study protocol for prospect trial to elucidate the utility of echocardiography-based cardiac output in acute heart failure (PREDICT)
ConclusionsThe PREDICT is expected to provide large data set to test the predictive value of echocardiographic LV output for early WHF in ADHF patients.
Source: Journal of Echocardiography - April 19, 2020 Category: Cardiology Source Type: research

Comparison of direct stenting with conventional strategy on myocardial impairments in ST-segment elevation myocardial infarction: a cardiac magnetic resonance imaging study
AbstractDirect stenting (DS) without pre-dilatation of the culprit lesion might improve myocardial perfusion and prognosis in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (STEMI); however, some studies report conflicting results. We investigated whether DS provides incremental myocardial benefits over conventional stenting (CS) in STEMI patients based on cardiac magnetic resonance imaging (CMR) measures. Reperfused patients who underwent CMR examinations within 1  week of STEMI onset were selected from a multicenter CMR registry of STEMI (NCT: 03768453). Patients were strat...
Source: The International Journal of Cardiovascular Imaging - March 11, 2020 Category: Radiology Source Type: research

The Role of Cardiovascular Magnetic Resonance in Inflammatory Arthropathies and Systemic Rheumatic Diseases
AbstractPurpose of the ReviewIn this review, the role of cardiovascular magnetic resonance (CMR), magnetic resonance angiography (MRA) and magnetic resonance spectroscopy (MRS) in the diagnosis, risk stratification, management and prognostication of inflammatory arthropathies and systemic rheumatic diseases (IASRD) is discussed. There have been several recent publications and it is timely to place into perspective the rapidly evolving concepts of advanced imaging in IASRDs through review and critical appraisal of the literature. IASRD are multisystemic autoimmune disorders with predilection for cardiovascular involvement a...
Source: Current Radiology Reports - March 5, 2020 Category: Radiology Source Type: research

Arrhythmia susceptibility in a rat model of acute atrial dilation
In conclusion, CV decrease is not sufficient to promote arrhythmias; enlargement of atrial surface is essential to create a substrate for acute reentry-based arrhythmias.
Source: Progress in Biophysics and Molecular Biology - February 14, 2020 Category: Molecular Biology Source Type: research

Prognostic value of 99m Tc-ECD brain perfusion SPECT in patients with atrial fibrillation and dementia
ConclusionThis study demonstrated that decreased cerebral blood flow in the temporo-parieto-occipital lobe could be a potential prognostic value in patients with both AF and dementia.
Source: EJNMMI Research - January 9, 2020 Category: Radiology Source Type: research