Cellular senomic measurements in Cognition-Based Evolution
Publication date: Available online 30 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): William B. Miller, František Baluška, John S. Torday (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 31, 2020 Category: Molecular Biology Source Type: research

Comparison of CryoEM and X-ray structures of dimethylformamidase
Publication date: Available online 28 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Kutti R. Vinothkumar, Chetan Arya, Gurunath Ramanathan, Ramaswamy Subramanian (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 29, 2020 Category: Molecular Biology Source Type: research

Structural interpretation of cryo-EM image reconstructions
Publication date: Available online 29 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Maximilian Beckers, Daniel Mann, Carsten Sachse (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 29, 2020 Category: Molecular Biology Source Type: research

Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca2+ entry after pressure-overload induced cardiac remodelling
Publication date: Available online 29 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Juan E. Camacho Londoño, Vladimir Kuryshev, Markus Zorn, Kathrin Saar, Qinghai Tian, Norbert Hübner, Peter Nawroth, Alexander Dietrich, Lutz Birnbaumer, Peter Lipp, Christoph Dieterich, Marc Freichel (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 29, 2020 Category: Molecular Biology Source Type: research

Evidence for DNA resonance signaling via longitudinal hydrogen bonds
Publication date: Available online 23 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Ivan Savelyev, Max Myakishev-Rempel (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 24, 2020 Category: Molecular Biology Source Type: research

In-silico human electro-mechanical ventricular modelling and simulation for drug-induced pro-arrhythmia and inotropic risk assessment
Publication date: Available online 22 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Francesca Margara, Zhinuo J. Wang, Francesc Levrero-Florencio, Alfonso Santiago, Mariano Vázquez, Alfonso Bueno-Orovio, Blanca Rodriguez (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 24, 2020 Category: Molecular Biology Source Type: research

Computational models of cardiac hypertrophy
Publication date: Available online 21 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Kyoko Yoshida, Jeffrey W. Holmes (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 22, 2020 Category: Molecular Biology Source Type: research

Tools for visualizing and analyzing Fourier space sampling in Cryo-EM
Publication date: Available online 6 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Philip R. Baldwin, Dmitry Lyumkis (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 7, 2020 Category: Molecular Biology Source Type: research

Intrinsic disorder in proteins: Relevance to protein assemblies, drug design and host-pathogen interactions
Publication date: Available online 3 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Tom L. Blundell, Munishwar N. Gupta, Seyed E. Hasnain (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 5, 2020 Category: Molecular Biology Source Type: research

High resolution single particle Cryo-EM refinement using JSPR
Publication date: Available online 3 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Chen Sun, Brenda Gonzalez, Frank S. Vago, Wen Jiang (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 3, 2020 Category: Molecular Biology Source Type: research

The origin of the heartbeat and theories of muscle contraction. Physiological concepts and conflicts in the 19th century
Publication date: Available online 3 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Johann P. Kuhtz-Buschbeck, Jochen Schaefer, Nicolaus Wilder, Wilhelm T. Wolze (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 3, 2020 Category: Molecular Biology Source Type: research

Distribution of data in cellular electrophysiology: Is it always normal?
Publication date: Available online 1 July 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Roman Kula, Markéta Bébarová, Peter Matejovič, Jiří Šimurda, Michal Pásek (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - July 1, 2020 Category: Molecular Biology Source Type: research

Toward more accurate data in cardiac cellular electrophysiology
Publication date: Available online 23 June 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Markéta Bébarová, Michal Pásek, Ivan Zahradník (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - June 24, 2020 Category: Molecular Biology Source Type: research

Towards high-throughput in situ structural biology using electron cryotomography
Publication date: Available online 21 June 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Jan Böhning, Tanmay A.M. Bharat (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - June 21, 2020 Category: Molecular Biology Source Type: research

TRPV2 channel-based therapies in the cardiovascular field. Molecular underpinnings of clinically relevant therapies
Publication date: Available online 18 June 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Brian O'Connor, Nathan Robbins, Sheryl E. Koch, Jack Rubinstein (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - June 19, 2020 Category: Molecular Biology Source Type: research

Cellular metabolism and colloids: Realistically linking physiology and biological physical chemistry
Publication date: Available online 18 June 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Luis A. Bagatolli, Agustín Mangiarotti, Roberto P. Stock (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - June 19, 2020 Category: Molecular Biology Source Type: research

Editorial Board
Publication date: August 2020Source: Progress in Biophysics and Molecular Biology, Volume 154Author(s): (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - June 17, 2020 Category: Molecular Biology Source Type: research

Editorial Board
Publication date: September 2020Source: Progress in Biophysics and Molecular Biology, Volume 155Author(s): (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - June 17, 2020 Category: Molecular Biology Source Type: research

Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system
Publication date: Available online 15 June 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Felix Wiedmann, Susanne Rinné, Birgit Donner, Niels Decher, Hugo A. Katus, Constanze Schmidt (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - June 16, 2020 Category: Molecular Biology Source Type: research

Localized reconstruction in scipion expedites the analysis of symmetry mismatches in Cryo-EM data
Publication date: Available online 26 May 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Vahid Abrishami, Serban L. Ilca, Josue Gomez-Blanco, Ilona Rissanen, José Miguel de la Rosa-Trevín, Vijay S. Reddy, José-Maria Carazo, Juha T. Huiskonen (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 26, 2020 Category: Molecular Biology Source Type: research

The role of pacing rate in the modulation of mechano-induced immediate and delayed changes in the force and Ca-transient of cardiac muscle
Publication date: Available online 23 May 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Oleg Lookin, Xenia Butova, Yuri Protsenko (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 23, 2020 Category: Molecular Biology Source Type: research

Ca2+ currents in cardiomyocytes: How to improve interpretation of patch clamp data?
Publication date: Available online 18 May 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Djemail Ismaili, Bastiaan Geelhoed, Torsten Christ (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 20, 2020 Category: Molecular Biology Source Type: research

A new simple approach to estimation of membrane capacitance from current responses to voltage clamp steps
Publication date: Available online 16 May 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Jiří Šimurda, Milena Šimurdová, Olga Švecová (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 17, 2020 Category: Molecular Biology Source Type: research

The problem of accuracy in single-channel open probability measurements
Publication date: Available online 13 May 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Alexandra Zahradníková, Bogdan Iaparov, Ivan Zahradník (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 14, 2020 Category: Molecular Biology Source Type: research

Novel optics-based approaches for cardiac electrophysiology
Publication date: Available online 12 May 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): G. Bub, M. Mongillo, G. Smith, L. Sacconi (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 12, 2020 Category: Molecular Biology Source Type: research

Diverse roles of mtDNA in schizophrenia: Implications in its pathophysiology and as biomarker for cognitive impairment
Publication date: Available online 11 May 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Samuel Suárez-Méndez, Dulce Dajheanne García-de la Cruz, Carlos Alfonso Tovilla-Zárate, Alma Delia Genis-Mendoza, Rosa Angélica Ramón-Torres, Thelma Beatriz González-Castro, Isela Esther Juárez-Rojop (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 11, 2020 Category: Molecular Biology Source Type: research

Re-visiting the Frank-Starling nexus
Publication date: Available online 11 May 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): June-Chiew Han, Denis Loiselle, Andrew Taberner, Kenneth Tran (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 11, 2020 Category: Molecular Biology Source Type: research

Editorial Board
Publication date: July 2020Source: Progress in Biophysics and Molecular Biology, Volume 153Author(s): (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 11, 2020 Category: Molecular Biology Source Type: research

Forecasting the timeframe of 2019-nCoV and human cells interaction with reverse engineering
Publication date: Available online 29 April 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Ayesha Sohail, Alessandro Nutini (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 5, 2020 Category: Molecular Biology Source Type: research

Forecasting the timeframe of coronavirus and human cells interaction with reverse engineering
Publication date: Available online 29 April 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Ayesha Sohail, Alessandro Nutini (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - May 1, 2020 Category: Molecular Biology Source Type: research

Ferroptosis as an emerging target in inflammatory diseases
Publication date: Available online 18 April 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Huimin Mao, Yunhe Zhao, Houxuan Li, Lang Lei (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - April 19, 2020 Category: Molecular Biology Source Type: research

Editorial Board
Publication date: May 2020Source: Progress in Biophysics and Molecular Biology, Volume 152Author(s): (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - April 4, 2020 Category: Molecular Biology Source Type: research

A specific role of magnetic isotopes in biological and ecological systems. Physics and biophysics beyond
Publication date: Available online 26 March 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Anatoly L. Buchachenko, Alexander A. Bukhvostov, Kirill V. Ermakov, Dmitry A. Kuznetsov (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - March 27, 2020 Category: Molecular Biology Source Type: research

Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies
Publication date: Available online 15 March 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Henry Sutanto, Aurore Lyon, Joost Lumens, Ulrich Schotten, Dobromir Dobrev, Jordi Heijman (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - March 26, 2020 Category: Molecular Biology Source Type: research

Non-canonical roles of connexins
Publication date: Available online 24 March 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Raf Van Campenhout, Axelle Cooreman, Kaat Leroy, Olga M. Rusiecka, Pieter Van Brantegem, Pieter Annaert, Serge Muyldermans, Nick Devoogdt, Bruno Cogliati, Brenda R. Kwak, Mathieu Vinken (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - March 26, 2020 Category: Molecular Biology Source Type: research

Accuracy considerations for capacitance estimation by voltage steps in cardiomyocytes
Publication date: Available online 23 March 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Dieter Platzer, Klaus Zorn-Pauly (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - March 24, 2020 Category: Molecular Biology Source Type: research

Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies
Publication date: Available online 15 March 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Henry Sutanto, Aurore Lyon, Joost Lumens, Ulrich Schotten, Dobromir Dobrev, Jordi Heijman (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - March 17, 2020 Category: Molecular Biology Source Type: research

Transfer RNA: The molecular demiurge in the origin of biological systems
Publication date: Available online 24 February 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Sávio Torres de Farias, Marco V. José (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - February 26, 2020 Category: Molecular Biology Source Type: research

Editorial: Charles Darwin, Jean-Baptiste Lamarck, and 21st century arguments on the fundamentals of biology.
Publication date: Available online 21 February 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Denis Noble (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - February 23, 2020 Category: Molecular Biology Source Type: research

Introduction: Novel insights into TB research and drug discovery
Publication date: Available online 20 February 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Gerhard GrüberAbstractMycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), kills more people than any other bacterium. TB control is threatened by the continued spread of drug resistance; multi-drug and extensively drug resistant Mtb require longer, more costly, treatment with multiple drugs causing worse side effects and have a lower likelihood of treatment success. The urgent need for better treatment options for drug resistant Mtb has led the World Health Organization to prioritiz...
Source: Progress in Biophysics and Molecular Biology - February 20, 2020 Category: Molecular Biology Source Type: research

Targeting the cytochrome oxidases for drug development in mycobacteria
Publication date: Available online 18 February 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Bei Shi Lee, Ekaterina Sviriaeva, Kevin PetheAbstractMycobacterium tuberculosis strictly depends on oxygen to multiply, and the terminal oxidases are a vital part of the oxidative phosphorylation pathway. The bacterium possesses two aerobic respiratory branches: a cytochrome bcc-aa3 and a bacteria-specific cytochrome bd oxidase. The identification of small-molecule inhibitors of the cytochrome bcc-aa3 under numerous experimental conditions reflects the essentiality of the pathway for the optimum growth of M. tu...
Source: Progress in Biophysics and Molecular Biology - February 20, 2020 Category: Molecular Biology Source Type: research

Editorial
Publication date: Available online 18 February 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Chandra S. Verma, Tom Blundell (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - February 20, 2020 Category: Molecular Biology Source Type: research

Editorial Board
Publication date: March 2020Source: Progress in Biophysics and Molecular Biology, Volume 151Author(s): (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - February 20, 2020 Category: Molecular Biology Source Type: research

Beyond the Modern Synthesis: A Framework for a More Inclusive Biological Synthesis
Publication date: Available online 14 February 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Peter A. CorningAbstractMany theorists in recent years have been calling for evolutionary biology to move beyond the Modern Synthesis – the paradigm that has long provided the theoretical backbone for the discipline. Terms like “postmodern synthesis,” “integrative synthesis,” and “extended evolutionary synthesis” have been invoked by various critics in connection with the many recent developments that pose deep challenges – even contradictions – to the tradi...
Source: Progress in Biophysics and Molecular Biology - February 16, 2020 Category: Molecular Biology Source Type: research

Arrhythmia susceptibility in a rat model of acute atrial dilation
In conclusion, CV decrease is not sufficient to promote arrhythmias; enlargement of atrial surface is essential to create a substrate for acute reentry-based arrhythmias. (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - February 14, 2020 Category: Molecular Biology Source Type: research

T cell receptors, mechanosensors, catch bonds and immunotherapy
Publication date: Available online 30 January 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Jia-huai WangAbstractT-cell based immunity is mediated through specific T cell receptor (TCR) recognition of a small antigenic peptide in complex with a host immune molecule, major compatibility complex (pMHC). The interaction of a TCR and its pMHC ligand is generally quite weak, degenerate and biophysically unfavorable. Yet, the resulting immune response is extremely effective, being both sensitive and specific.Recent observations indicate that the TCR is an anisotropic mechanosensor. The force sensed by TCR&rs...
Source: Progress in Biophysics and Molecular Biology - January 30, 2020 Category: Molecular Biology Source Type: research

Editorial Board
Publication date: January 2020Source: Progress in Biophysics and Molecular Biology, Volume 150Author(s): (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - January 17, 2020 Category: Molecular Biology Source Type: research

The role of DNA demethylation in induction of stem cells
Publication date: Available online 1 January 2020Source: Progress in Biophysics and Molecular BiologyAuthor(s): Mohammad H. Ghazimoradi, Shirin FarivarAbstractDNA methylation is an epigenetic factor, which plays important roles in embryo and many other diseases development. This factor determines gene expression, and when half of them have CpG islands, DNA methylation and its enzyme effectors have been under the vast studies. Whole genome DNA demethylation is a crucial step of embryogenesis and also cell fate determination in embryos. Therefore, demethylation agents were used as a tool for dedifferentiation and transdiffer...
Source: Progress in Biophysics and Molecular Biology - January 2, 2020 Category: Molecular Biology Source Type: research

Temporal irregularity quantification and mapping of optical action potentials using wave morphology similarity
ConclusionOWS mapping provides an effective measure of temporal regularity that can be applied to optical datasets to detect and quantify temporal alterations in action potential morphology. This methodology provides a new metric for arrhythmia inducibility and scoring in optical mapping datasets. (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - January 1, 2020 Category: Molecular Biology Source Type: research

Polygenic scores are an even bigger social hazard: Commentary on: Baverstock, K. (2019) polygenic scores: Are they a public health hazard? Progress in Biophysics and Molecular Biology. Available online 6 August 2019
Publication date: Available online 27 December 2019Source: Progress in Biophysics and Molecular BiologyAuthor(s): Ken Richardson (Source: Progress in Biophysics and Molecular Biology)
Source: Progress in Biophysics and Molecular Biology - December 29, 2019 Category: Molecular Biology Source Type: research