Neurological Presentation in Roseola Infantum is Seldom Encephalitis in Immunocompetent Children
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 18, 2022 Category: Pediatrics Source Type: research

Human herpes simplex virus-6 (HHV-6) detection and seroprevalence among Qatari nationals and immigrants residing in Qatar
CONCLUSION: The seroprevalence of HHV-6 in Qatar was found to be similar to rates reported in other parts of the world.PMID:35757074 | PMC:PMC9216376 | DOI:10.1016/j.ijregi.2021.12.005 (Source: Herpes)
Source: Herpes - June 27, 2022 Category: Infectious Diseases Authors: Duaa W Al-Sadeq Hadeel T Zedan Nader Aldewik Alaa Elkhider Asalet Hicazi Nadin Younes Houssein H Ayoub Laith Abu Raddad Hadi M Yassine Gheyath K Nasrallah Source Type: research

Human herpes simplex virus-6 (HHV-6) detection and seroprevalence among Qatari nationals and immigrants residing in Qatar
CONCLUSION: The seroprevalence of HHV-6 in Qatar was found to be similar to rates reported in other parts of the world.PMID:35757074 | PMC:PMC9216376 | DOI:10.1016/j.ijregi.2021.12.005 (Source: Herpes)
Source: Herpes - June 27, 2022 Category: Infectious Diseases Authors: Duaa W Al-Sadeq Hadeel T Zedan Nader Aldewik Alaa Elkhider Asalet Hicazi Nadin Younes Houssein H Ayoub Laith Abu Raddad Hadi M Yassine Gheyath K Nasrallah Source Type: research

< em > Microvirga roseola < /em > sp. nov. and < em > Microvirga lenta < /em > sp. nov., isolated from Taklamakan Desert soil
Int J Syst Evol Microbiol. 2022 Jun;72(6). doi: 10.1099/ijsem.0.005409.ABSTRACTTwo Gram-negative, rod-shaped, non-spore-forming bacteria, designated SM9T and SM2T, were isolated from Taklamakan Desert soil samples. Phylogenetic analysis based on the 16S rRNA gene sequences showed that strains SM9T and SM2T had the highest sequence similarity to the type strains Microvirga indica BCRC 80972T and Microvirga soli NBRC 112417T with similarity values of 98.2 and 97.7 %, respectively, and Microvirga was among the predominant genera in the desert soil. The draft genomes of these two strains were 4.56 Mbp (SM9T) and 5.08 Mbp (SM2T...
Source: International Journal of Systematic and Evolutionary Microbiology - June 6, 2022 Category: Microbiology Authors: Xinran Du Qi Ran Jianing Wang Hong Jiang Jingjing Wang Yue-Zhong Li Source Type: research

< em > Microvirga roseola < /em > sp. nov. and < em > Microvirga lenta < /em > sp. nov., isolated from Taklamakan Desert soil
Int J Syst Evol Microbiol. 2022 Jun;72(6). doi: 10.1099/ijsem.0.005409.ABSTRACTTwo Gram-negative, rod-shaped, non-spore-forming bacteria, designated SM9T and SM2T, were isolated from Taklamakan Desert soil samples. Phylogenetic analysis based on the 16S rRNA gene sequences showed that strains SM9T and SM2T had the highest sequence similarity to the type strains Microvirga indica BCRC 80972T and Microvirga soli NBRC 112417T with similarity values of 98.2 and 97.7 %, respectively, and Microvirga was among the predominant genera in the desert soil. The draft genomes of these two strains were 4.56 Mbp (SM9T) and 5.08 Mbp (SM2T...
Source: International Journal of Systematic and Evolutionary Microbiology - June 6, 2022 Category: Microbiology Authors: Xinran Du Qi Ran Jianing Wang Hong Jiang Jingjing Wang Yue-Zhong Li Source Type: research

< em > Microvirga roseola < /em > sp. nov. and < em > Microvirga lenta < /em > sp. nov., isolated from Taklamakan Desert soil
Int J Syst Evol Microbiol. 2022 Jun;72(6). doi: 10.1099/ijsem.0.005409.ABSTRACTTwo Gram-negative, rod-shaped, non-spore-forming bacteria, designated SM9T and SM2T, were isolated from Taklamakan Desert soil samples. Phylogenetic analysis based on the 16S rRNA gene sequences showed that strains SM9T and SM2T had the highest sequence similarity to the type strains Microvirga indica BCRC 80972T and Microvirga soli NBRC 112417T with similarity values of 98.2 and 97.7 %, respectively, and Microvirga was among the predominant genera in the desert soil. The draft genomes of these two strains were 4.56 Mbp (SM9T) and 5.08 Mbp (SM2T...
Source: International Journal of Systematic and Evolutionary Microbiology - June 6, 2022 Category: Microbiology Authors: Xinran Du Qi Ran Jianing Wang Hong Jiang Jingjing Wang Yue-Zhong Li Source Type: research

Changes in Exanthema Subitum Incidence and Patient Age Distribution During the COVID-19 Pandemic in Japan
Incidences of community-acquired infectious diseases other than COVID-19 decreased during the coronavirus disease 2019 pandemic; however, exanthema subitum incidence before (2016–2019) and during the pandemic (2020) in Niigata, Japan, did not substantially differ, although the proportion of age less than 1-year-old was lower in 2020. These findings suggest that exanthema subitum is transmitted mainly among family members, not in the community. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - February 11, 2022 Category: Infectious Diseases Tags: COVID Reports Source Type: research

Roseola Infantum During the COVID-19 Pandemic
Conclusion: During the peak of the pandemic, children continued to present with fever because of viral infections other than COVID-19. (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - January 1, 2022 Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research

Human herpesvirus 6 myelitis after chimeric antigen receptor T-cell therapy
This article reports a fatal case of HHV-6 myelitis with quadriplegia after anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, highlighting an at-risk population for HHV-6 central nervous system (CNS) infection that has not been described previously. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - September 28, 2021 Category: Infectious Diseases Authors: Guy Handley, Fareed Khawaja, Divya S. Kondapi, Hun J. Lee, Gregory P. Kaufman, Sattva S. Neelapu, Luis E. Fayad, Sudhakar Tummala, Linda Chi, Paolo Strati, Victor E. Mulanovich Source Type: research

Reduced impact of viral load of HHV-6 in liquor on severity of AESD due to exanthema subitum: A case report and literature review
The most common causative pathogen of acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) was reported as HHV-6. Although excitotoxic injury with delayed neuronal death is considered to be a possible pathogenesis of AESD, the detailed pathophysiology remains unclear. (Source: Brain and Development)
Source: Brain and Development - May 7, 2021 Category: Neurology Authors: Ayaka Kasai, Jun Shimizu, Masanori Sato, Masatomo Kitamura, Yuji Inaba, Mitsuo Motobayashi Tags: Case Report Source Type: research

The Not-So-Soft Spot: Pathophysiology of the Bulging Fontanelle in Association With Roseola
Roseola infantum is a clinical syndrome characterized by high fever followed by the emergence of a rash. Case reports have documented an association between bulging fontanelles and roseola. We propose a novel mechanism for the development of intracranial hypertension caused by human herpesvirus 6–induced cytokine elevation leading to increased cerebrospinal fluid production. (Source: Pediatric Emergency Care)
Source: Pediatric Emergency Care - October 1, 2020 Category: Emergency Medicine Tags: Illustrative Cases Source Type: research

A rapid, simple screening toxicity test using desiccated bdelloid rotifers: Rotifer Activity Inhibition Test (RAIT).
Abstract A protocol for an ultra-rapid screening toxicity test is described using the rotifer Philodina acuticornis/roseola. The test can be executed in 30 min starting from the rehydration of desiccated life stages called tuns. Philodina tuns remain viable for years when maintained dry and at low temperature. They are very useful for conducting toxicity tests because the test animals do not require cultivation and are available to initiate tests anytime and anywhere. The swimming/crawling activity of rehydrated Philodina tuns is used as an endpoint to compare activity in control dilution water with inhibi...
Source: Environmental Science and Pollution Research International - May 26, 2020 Category: Environmental Health Authors: Snell TW, Persoone G Tags: Environ Sci Pollut Res Int Source Type: research

Current understanding of human herpesvirus 6 (HHV-6) chromosomal integration
Publication date: Available online 7 February 2020Source: Antiviral ResearchAuthor(s): Giulia Aimola, Georg Beythien, Amr Aswad, Benedikt B. KauferAbstractHuman herpesvirus 6A (HHV-6A) and 6B (HHV–6B) are members of the genus Roseolovirus in the Betaherpesvirinae subfamily. HHV-6B infects humans in the first years of life, has a seroprevalence of more than 90% and causes Roseola Infantum, but less is known about HHV-6A. While most other herpesviruses maintain their latent genome as a circular episome, HHV-6A and HHV-6B (HHV-6A/B) have been shown to integrate their genome into the telomeres of infected cells. HHV-6A/B can...
Source: Antiviral Therapy - February 8, 2020 Category: Virology Source Type: research

Current understanding of human herpesvirus 6 (HHV-6) chromosomal integration.
Abstract Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are members of the genus Roseolovirus in the Betaherpesvirinae subfamily. HHV-6B infects humans in the first years of life, has a seroprevalence of more than 90% and causes Roseola Infantum, but less is known about HHV-6A. While most other herpesviruses maintain their latent genome as a circular episome, HHV-6A and HHV-6B (HHV-6A/B) have been shown to integrate their genome into the telomeres of infected cells. HHV-6A/B can also integrate into the chromosomes of germ cells, resulting in individuals carrying a copy of the virus genome in every nucleated...
Source: Antiviral Research - February 6, 2020 Category: Virology Authors: Aimola G, Beythien G, Aswad A, Kaufer BB Tags: Antiviral Res Source Type: research

A Systematic Review of Sodium Disorders in HHV-6 Encephalitis
HHV-6 is the collective name of two distinct viral species, HHV-6A and HHV-6B, both members of the subfamily betaherpesvirinae, which also includes cytomegalovirus (CMV) and HHV-7. Seropositivity to HHV-6 is greater than 95% in adults in developed countries1 with nearly 80% acquiring the virus by the age of 2 years.2 Of the two species, HHV-6B makes up the vast majority of symptomatic primary infections in infants 3 and is the causative agent of exanthema subitum, also known as roseola infantum. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 2, 2020 Category: Hematology Authors: NikolasC. Victoria, TuanL. Phan, KrishnaA. Agarwal Source Type: research