Safety, pharmacokinetics and pharmacodynamics of SYN023 alone or in combination with a rabies vaccine: An open, parallel, single dose, phase 1 bridging study in healthy Chinese subjects
Publication date: Available online 19 October 2020Source: Antiviral ResearchAuthor(s): Yanhua Ding, Min Wu, Hong Zhang, Xiaoxue Zhu, Yue Hu, Xiaojiao Li, Jingrui Liu, Eric Tsao, Ming Liu, Cuiyun Li (Source: Antiviral Therapy)
Source: Antiviral Therapy - October 20, 2020 Category: Virology Source Type: research

Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes
Publication date: Available online 19 October 2020Source: Antiviral ResearchAuthor(s): Seong Woo Choi, Jin Soo Shin, Soon-Jung Park, Eunhye Jung, Yun-Gwi Park, Jiho Lee, Sung Joon Kim, Hun-Jun Park, Jung-Hoon Lee, Sung-Min Park, Sung-Hwan Moon, Kiwon Ban, Yun Young Go (Source: Antiviral Therapy)
Source: Antiviral Therapy - October 20, 2020 Category: Virology Source Type: research

Betulinic Acid exhibits antiviral effects against dengue virus infection
Publication date: Available online 17 October 2020Source: Antiviral ResearchAuthor(s): Marcus Wing Choy Loe, Erwei Hao, Meiling Chen, Cong Li, Regina Ching Hua Lee, Isabelle Xin Yu Zhu, Zi Yun Teo, Wei-Xin Chin, Xiaotao Hou, JiaGang Deng, Justin Jang Hann Chu (Source: Antiviral Therapy)
Source: Antiviral Therapy - October 19, 2020 Category: Virology Source Type: research

Anti-viral effect in chronic hepatitis B patients with normal or mildly elevated alanine aminotransferase
Publication date: Available online 13 October 2020Source: Antiviral ResearchAuthor(s): Qingqing Zhao, Kehui Liu, Xiaojun Zhu, Lei Yan, Yezhou Ding, Yumin Xu, Shike Lou, Gangde Zhao, Qing Xie, Yueqiu Gao, Shisan Bao, Hui Wang (Source: Antiviral Therapy)
Source: Antiviral Therapy - October 15, 2020 Category: Virology Source Type: research

Unexpected complete recovery of a patient with severe tick-borne encephalitis treated with favipiravir
Publication date: Available online 12 October 2020Source: Antiviral ResearchAuthor(s): Razvan Bologheanu, Lorenz Schubert, Majda Thurnher, Judith Schiefer, Isabel Santonja, Heidemarie Holzmann, Zoe Österreicher, Selma Tobudic, Stefan Winkler, Peter Faybik, Christoph Steininger, Florian Thalhammer (Source: Antiviral Therapy)
Source: Antiviral Therapy - October 12, 2020 Category: Virology Source Type: research

Immune response to varicella-zoster virus before and after renal transplantation
Publication date: November 2020Source: Antiviral Research, Volume 183Author(s): Christien Rondaan, Anoek A.E. de Joode, Lei Wang, Mark Siderius, Elisabeth Raveling-Eelsing, Coretta van Leer-Buter, Sander van Assen, Nicolaas A. Bos, Johanna Westra (Source: Antiviral Therapy)
Source: Antiviral Therapy - October 7, 2020 Category: Virology Source Type: research

Characterization of hepatitis B virus surface antigen particles expressed in stably transformed mammalian cell lines containing the large, middle and small surface protein
Publication date: November 2020Source: Antiviral Research, Volume 183Author(s): Juan Manuel Battagliotti, Diego Fontana, Marina Etcheverrigaray, Ricardo Kratje, Claudio Prieto (Source: Antiviral Therapy)
Source: Antiviral Therapy - October 2, 2020 Category: Virology Source Type: research

Duration of fever and symptoms in children after treatment with baloxavir marboxil and oseltamivir during the 2018-2019 season and detection of variant influenza A viruses with polymerase acidic subunit substitutions
Publication date: Available online 25 September 2020Source: Antiviral ResearchAuthor(s): Reiko Saito, Hidekazu Osada, Keita Wagatsuma, Irina Chon, Isamu Sato, Takashi Kawashima, Tadashi Saito, Naoki Kodo, Yasuhiko Ono, Yasushi Shimada, WintWint Phyu, Yugo Shobugawa (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 27, 2020 Category: Virology Source Type: research

Editorial Board
Publication date: October 2020Source: Antiviral Research, Volume 182Author(s): (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 27, 2020 Category: Virology Source Type: research

Diketo acids inhibit the cap-snatching endonuclease of several Bunyavirales
Publication date: Available online 24 September 2020Source: Antiviral ResearchAuthor(s): Yaiza Fernández-García, Sebastiaan ter Horst, Marcella Bassetto, Andrea Brancale, Johan Neyts, Dominga Rogolino, Mario Sechi, Mauro Carcelli, Stephan Günther, Joana Rocha-Pereira (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 25, 2020 Category: Virology Source Type: research

Tenofovir alafenamide does not inhibit mitochondrial function and cholesterol biosynthesis in human T lymphoblastoid cell line
Publication date: Available online 24 September 2020Source: Antiviral ResearchAuthor(s): Min Li, Lei Zhou, Harold G. Dorsey, Charles Musoff, Dereck Amakye Jnr, Natalie Schoen, Kweku Djan, Elijah Paintsil (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 25, 2020 Category: Virology Source Type: research

Generation of a reporter yellow fever virus for high throughput antiviral assays
Publication date: Available online 24 September 2020Source: Antiviral ResearchAuthor(s): Ricardo Sanchez-Velazquez, Giuditta de Lorenzo, Rapeepat Tandavanitj, Chayanee Setthapramote, Peter J. Bredenbeek, Leonia Bozzacco, Margaret R. MacDonald, Jordan J. Clark, Charles M. Rice, Arvind H. Patel, Alain Kohl, Margus Varjak (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 25, 2020 Category: Virology Source Type: research

Avian anti-NS1 IgY antibodies neutralize dengue virus infection and protect against lethal dengue virus challenge
Publication date: Available online 23 September 2020Source: Antiviral ResearchAuthor(s): Kyle L. O’Donnell, Diego A. Espinosa, Henry Puerta-Guardo, Scott B. Biering, James Schiltz, Matthew L. Nilles, Jeffrey Li, Eva Harris, David S. Bradley (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 24, 2020 Category: Virology Source Type: research

Cryptotanshinone Protects Porcine Alveolar Macrophages from Infection with Porcine Reproductive and Respiratory Syndrome Virus
Publication date: Available online 19 September 2020Source: Antiviral ResearchAuthor(s): Chang Huang, Jiaqi Zhu, Ling Wang, Alexander Chu, Yexuan Yin, Kaneha Vali, Antonio Garmendia, Young Tang (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 20, 2020 Category: Virology Source Type: research

A synthetic STING agonist inhibits the replication of Human Parainfluenza Virus 3 and Rhinovirus 16 through distinct mechanisms
Publication date: Available online 17 September 2020Source: Antiviral ResearchAuthor(s): Qingyuan Zhu, Hui Hu, Haixia Liu, Hong Shen, Zhipeng Yan, Lu Gao (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 18, 2020 Category: Virology Source Type: research

A biaryl sulfonamide derivative as a novel inhibitor of filovirus infection
Publication date: Available online 15 September 2020Source: Antiviral ResearchAuthor(s): Mao Isono, Wakako Furuyama, Makoto Kuroda, Tatsunari Kondoh, Manabu Igarashi, Masahiro Kajihara, Reiko Yoshida, Rashid Manzoor, Kosuke Okuya, Hiroko Miyamoto, Heinz Feldmann, Andrea Marzi, Masahiro Sakaitani, Asuka Nanbo, Ayato Takada (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 16, 2020 Category: Virology Source Type: research

Vector-borne Viruses in Turkey: A Systematic Review and Bibliography
Publication date: Available online 16 September 2020Source: Antiviral ResearchAuthor(s): Koray Ergünay, Ceylan Polat, Aykut Özkul (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 16, 2020 Category: Virology Source Type: research

Castanospermine reduces Zika virus infection-associated seizure by inhibiting both the viral load and inflammation in mouse models
Publication date: Available online 16 September 2020Source: Antiviral ResearchAuthor(s): Anil M. Tharappel, Yichen Cheng, Eric H. Holmes, Gary K. Ostrander, Hengli Tang (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 16, 2020 Category: Virology Source Type: research

Identification of antiviral compounds against equid herpesvirus-1 using real-time cell assay screening: efficacy of decitabine and valganciclovir alone or in combination
Publication date: Available online 11 September 2020Source: Antiviral ResearchAuthor(s): Côme Thieulent, Erika Hue, Gabrielle Sutton, Christine Fortier, Patrick Dallemagne, Stephan Zientara, Hélène Munier-Lehmann, Aymeric Hans, Romain Paillot, Pierre-Olivier Vidalain, Stéphane Pronost (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 12, 2020 Category: Virology Source Type: research

A synthetic stigmastane displays antiadenoviral activity and reduces the inflammatory response to viral infection
Publication date: Available online 9 September 2020Source: Antiviral ResearchAuthor(s): Flavia M. Michelini, Carlos A. Bueno, Yanina B. Areco, Laura E. Alché (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 10, 2020 Category: Virology Source Type: research

Structural-based virtual screening and in vitro assays for small molecules inhibiting the feline coronavirus 3CL protease as a surrogate platform for coronaviruses
Publication date: Available online 7 September 2020Source: Antiviral ResearchAuthor(s): Sirin Theerawatanasirikul, Chih Jung Kuo, Nanthawan Phecharat, Jullada Chootip, Chalermpol Lekcharoensuk, Porntippa Lekcharoensuk (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 8, 2020 Category: Virology Source Type: research

A Dengue type 2 reporter virus assay amenable to high-throughput screening
Publication date: Available online 6 September 2020Source: Antiviral ResearchAuthor(s): Li-Hsin Li, Suzanne J.F. Kaptein, Michael A. Schmid, Joanna Zmurko, Pieter Leyssen, Johan Neyts, Kai Dallmeier (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 7, 2020 Category: Virology Source Type: research

Lassa virus antigen distribution and inflammation in the ear of infected strain 13/N guinea pigs
Publication date: Available online 6 September 2020Source: Antiviral ResearchAuthor(s): Thanhthao Huynh, Joy M. Gary, Stephen R. Welch, JoAnn Coleman-McCray, Jessica R. Harmon, Markus H. Kainulainen, Brigid C. Bollweg, Jana M. Ritter, Wun-Ju Shieh, Stuart T. Nichol, Sherif R. Zaki, Christina F. Spiropoulou, Jessica R. Spengler (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 7, 2020 Category: Virology Source Type: research

Interference of dengue replication by blocking the access of 3′ SL RNA to the viral RNA-dependent RNA polymerase
Publication date: October 2020Source: Antiviral Research, Volume 182Author(s): Chairat Tunghirun, Veerakorn Narkthong, Wanpen Chaicumpa, Sarin Chimnaronk (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 7, 2020 Category: Virology Source Type: research

Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry
Publication date: Available online 5 September 2020Source: Antiviral ResearchAuthor(s): Zachary A. Gurard-Levin, Cheng Liu, Andreas Jekle, Ruchika Jaisinghani, Suping Ren, Koen Vandyck, Dirk Jochmans, Pieter Leyssen, Johan Neyts, Lawrence M. Blatt, Leonid Beigelman, Julian A. Symons, Pierre Raboisson, Michael D. Scholle, Jerome Deval (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 6, 2020 Category: Virology Source Type: research

Identification of a protective epitope in Japanese encephalitis virus NS1 protein
Publication date: Available online 6 September 2020Source: Antiviral ResearchAuthor(s): Dengyuan Zhou, Chao Pei, Zhaoxia Liu, Kelu Yang, Qiuyan Li, Huanchun Chen, Shengbo Cao, Yunfeng Song (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 6, 2020 Category: Virology Source Type: research

Activation of platelet-derived growth factor receptor β in the severe fever with thrombocytopenia syndrome virus infection
Publication date: Available online 1 September 2020Source: Antiviral ResearchAuthor(s): Hideki Tani, Miyuki Kimura, Hiroshi Yamada, Hikaru Fujii, Satoshi Taniguchi, Masayuki Shimojima, Shuetsu Fukushi, Shigeru Morikawa, Masayuki Saijo (Source: Antiviral Therapy)
Source: Antiviral Therapy - September 2, 2020 Category: Virology Source Type: research

Hepatitis B virus biology and life cycle
Publication date: Available online 28 August 2020Source: Antiviral ResearchAuthor(s): Senko Tsukuda, Koichi Watashi (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 30, 2020 Category: Virology Source Type: research

Enzymatically synthesized 2′-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity
Publication date: October 2020Source: Antiviral Research, Volume 182Author(s): Alesia A. Levanova, Kiira M. Kalke, Liisa M. Lund, Nina Sipari, Mohammadreza Sadeghi, Marie C. Nyman, Henrik Paavilainen, Veijo Hukkanen, Minna M. Poranen (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 27, 2020 Category: Virology Source Type: research

ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity
Publication date: Available online 26 August 2020Source: Antiviral ResearchAuthor(s): Zhiqiang Xia, Luyao Wang, Songryong Li, Wei Tang, Fang Sun, Yingliang Wu, Lixia Miao, Zhijian Cao (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 26, 2020 Category: Virology Source Type: research

Interference of dengue replication by blocking the access of 3´ SL RNA to the viral RNA-dependent RNA polymerase
Publication date: Available online 22 August 2020Source: Antiviral ResearchAuthor(s): Chairat Tunghirun, Veerakorn Narkthong, Wanpen Chaicumpa, Sarin Chimnaronk (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 22, 2020 Category: Virology Source Type: research

Editorial Board
Publication date: September 2020Source: Antiviral Research, Volume 181Author(s): (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 22, 2020 Category: Virology Source Type: research

Vaccine strain of O/ME-SA/Ind-2001e of foot-and-mouth disease virus provides high immunogenicity and broad antigenic coverage
Publication date: Available online 20 August 2020Source: Antiviral ResearchAuthor(s): Gyeongmin Lee, Ji-Hyeon Hwang, Jong-Hyeon Park, Min Ja Lee, Byounghan Kim, Su-Mi Kim (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 21, 2020 Category: Virology Source Type: research

Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B
Publication date: Available online 17 August 2020Source: Antiviral ResearchAuthor(s): Usha Viswanathan, Nagraj Mani, Zhanying Hu, Haiqun Ban, Yanming Du, Jin Hu, Jinhong Chang, Ju-Tao Guo (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 18, 2020 Category: Virology Source Type: research

Repurposing Pyramax®, Quinacrine and Tilorone as Treatments for Ebola Virus Disease
Publication date: Available online 13 August 2020Source: Antiviral ResearchAuthor(s): Thomas R. Lane, Julie Dyall, Luke Mercer, Caleb Goodin, Daniel H. Foil, Huanying Zhou, Elena Postnikova, Janie Y. Liang, Michael R. Holbrook, Peter B. Madrid, Sean Ekins (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 14, 2020 Category: Virology Source Type: research

Development of antibody-based assays for high throughput discovery and mechanistic study of antiviral agents against yellow fever virus
Publication date: Available online 14 August 2020Source: Antiviral ResearchAuthor(s): Zhao Gao, Lin Zhang, Julia Ma, Andrea Jurado, Seon-Hui Hong, Ju-Tao Guo, Charles M. Rice, Margaret R. MacDonald, Jinhong Chang (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 14, 2020 Category: Virology Source Type: research

Detection of baloxavir resistant influenza A viruses using next generation sequencing and pyrosequencing methods
Publication date: Available online 14 August 2020Source: Antiviral ResearchAuthor(s): Mira C. Patel, Vasiliy P. Mishin, Juan A. De La Cruz, Anton Chesnokov, Ha T. Nguyen, Malania M. Wilson, John Barnes, Rebecca J.G. Kondor, David E. Wentworth, Larisa V. Gubareva (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 14, 2020 Category: Virology Source Type: research

Producing Physicochemical Property Consensus Alphavirus Protein Antigens for Broad Spectrum Vaccine Design
Publication date: Available online 12 August 2020Source: Antiviral ResearchAuthor(s): Wendy S. Baker, Surendra Negi, Werner Braun, Catherine H. Schein (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 14, 2020 Category: Virology Source Type: research

Viperin protein inhibits the replication of caprine parainfluenza virus 3 (CPIV 3) by interaction with viral N protein
Publication date: Available online 12 August 2020Source: Antiviral ResearchAuthor(s): Wenliang Li, Jizong Li, Min Sun, Leilei Yang, Li Mao, Fei Hao, Maojun Liu, Wenwen Zhang (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 14, 2020 Category: Virology Source Type: research

Enzymatically synthesized 2'-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity
Publication date: Available online 13 August 2020Source: Antiviral ResearchAuthor(s): Alesia A. Levanova, Kiira M. Kalke, Liisa M. Lund, Nina Sipari, Mohammadreza Sadeghi, Marie C. Nyman, Henrik Paavilainen, Veijo Hukkanen, Minna M. Poranen (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 14, 2020 Category: Virology Source Type: research

Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses
Publication date: October 2020Source: Antiviral Research, Volume 182Author(s): K. Reddisiva Prasanth, Minato Hirano, W. Samuel Fagg, Eileen T. McAnarney, Chao Shan, Xuping Xie, Adam Hage, Colette A. Pietzsch, Alexander Bukreyev, Ricardo Rajsbaum, Pei-Yong Shi, Mark T. Bedford, Shelton S. Bradrick, Vineet Menachery, Mariano A. Garcia-Blanco (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 14, 2020 Category: Virology Source Type: research

Viral fitness of MHV-68 viruses harboring drug resistance mutations in the protein kinase or thymidine kinase
Publication date: Available online 5 August 2020Source: Antiviral ResearchAuthor(s): Erika Trompet, Dimitrios Topalis, Sarah Gillemot, Robert Snoeck, Graciela Andrei (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 13, 2020 Category: Virology Source Type: research

Effect of brincidofovir on adenovirus and A549 cells transcriptome profiles
Publication date: Available online 5 August 2020Source: Antiviral ResearchAuthor(s): Maud Salmona, Linda Feghoul, Séverine Mercier-Delarue, Elise Diaz, Marion Splitberger, Alix Armero, Jean-Hugues Dalle, Jacques Dutrieux, Jérôme LeGoff (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 13, 2020 Category: Virology Source Type: research

Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses
Publication date: Available online 5 August 2020Source: Antiviral ResearchAuthor(s): Eva Konkolova, Milan Dejmek, Hubert Hřebabecký, Michal Šála, Jiří Böserle, Radim Nencka, Evzen Boura (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 13, 2020 Category: Virology Source Type: research

Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3
Publication date: Available online 5 August 2020Source: Antiviral ResearchAuthor(s): Wint Wint Phoo, Abbas El Sahili, ZhenZhen Zhang, Ming Wei Chen, Chong Wai Liew, Julien Lescar, Subhash G. Vasudevan, Dahai Luo (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 13, 2020 Category: Virology Source Type: research

Iminosugars: a host-targeted approach to combat Flaviviridae infections
Publication date: Available online 5 August 2020Source: Antiviral ResearchAuthor(s): Lisa Evans DeWald, Chloe Starr, Terry Butters, Anthony Treston, Kelly L. Warfield (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 13, 2020 Category: Virology Source Type: research

Small molecule inhibitors possibly targeting the rearrangement of Zika virus Envelope protein
Publication date: Available online 9 August 2020Source: Antiviral ResearchAuthor(s): Nitin Sharma, Oliver Prosser, Prateek Kumar, Andrew Tuplin, Rajanish Giri (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 13, 2020 Category: Virology Source Type: research

Strain-dependent disease and response to favipiravir treatment in mice infected with Chikungunya virus
Publication date: Available online 10 August 2020Source: Antiviral ResearchAuthor(s): Justin G. Julander, Ashley Dagley, Makda Gebre, Takashi Komeno, Nozomi Nakajima, Donald F. Smee, Yousuke Furuta (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 13, 2020 Category: Virology Source Type: research

Animal models for the study of human hepatitis B and D virus infection: new insights and progress
Publication date: Available online 3 August 2020Source: Antiviral ResearchAuthor(s): Benjamin J. Burwitz, Zhongmin Zhou, Wenhui Li (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 5, 2020 Category: Virology Source Type: research

Murine norovirus replicase augments RIG-I-like receptors-mediated antiviral interferon response
Publication date: Available online 2 August 2020Source: Antiviral ResearchAuthor(s): Peifa Yu, Yang Li, Yunlong Li, Zhijiang Miao, Yining Wang, Maikel P. Peppelenbosch, Qiuwei Pan (Source: Antiviral Therapy)
Source: Antiviral Therapy - August 3, 2020 Category: Virology Source Type: research