Infectious mononucleosis: new concepts in clinical presentation, epidemiology, and host response
Curr Opin Infect Dis. 2024 Mar 27. doi: 10.1097/QCO.0000000000001012. Online ahead of print.ABSTRACTPURPOSE OF THE REVIEW: Infectious mononucleosis (IM) is an infectious disease that presents clinically in only a small percentage of individuals despite almost universal infection with the causative agent. Here, we review the latest concepts in the clinical presentation, epidemiology, and host response of this disease.RECENT FINDINGS: Several recently published papers/reviews describe IM as a condition caused by one of several etiologic agents including, cytomegalovirus (HHV-5), Roseola virus (HHV-6) and Toxoplasmosis amongs...
Source: Herpes - March 26, 2024 Category: Infectious Diseases Authors: Patrick Naughton Frances Enright Brigid Lucey Source Type: research
Infectious mononucleosis: new concepts in clinical presentation, epidemiology, and host response
Curr Opin Infect Dis. 2024 Mar 27. doi: 10.1097/QCO.0000000000001012. Online ahead of print.ABSTRACTPURPOSE OF THE REVIEW: Infectious mononucleosis (IM) is an infectious disease that presents clinically in only a small percentage of individuals despite almost universal infection with the causative agent. Here, we review the latest concepts in the clinical presentation, epidemiology, and host response of this disease.RECENT FINDINGS: Several recently published papers/reviews describe IM as a condition caused by one of several etiologic agents including, cytomegalovirus (HHV-5), Roseola virus (HHV-6) and Toxoplasmosis amongs...
Source: Herpes - March 26, 2024 Category: Infectious Diseases Authors: Patrick Naughton Frances Enright Brigid Lucey Source Type: research
A case of Stevens-Johnson syndrome treated with oral cyclosporine
J Family Med Prim Care. 2023 Dec;12(12):3425-3428. doi: 10.4103/jfmpc.jfmpc_1162_23. Epub 2023 Dec 21.ABSTRACTStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin inhibitor, has been reported to have a promising therapeutic effect in SJS/TEN patients with few side effects. Diagnosis of SJS/TEN in children is especially challenging as many of the symptoms mimic that of an upper respi...
Source: Primary Care - February 16, 2024 Category: Primary Care Authors: Victoria Griffith Amanda Ramnot Sydney R Resnik Barry I Resnik Source Type: research
A case of Stevens-Johnson syndrome treated with oral cyclosporine
J Family Med Prim Care. 2023 Dec;12(12):3425-3428. doi: 10.4103/jfmpc.jfmpc_1162_23. Epub 2023 Dec 21.ABSTRACTStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin inhibitor, has been reported to have a promising therapeutic effect in SJS/TEN patients with few side effects. Diagnosis of SJS/TEN in children is especially challenging as many of the symptoms mimic that of an upper respi...
Source: Herpes - February 16, 2024 Category: Infectious Diseases Authors: Victoria Griffith Amanda Ramnot Sydney R Resnik Barry I Resnik Source Type: research
A case of Stevens-Johnson syndrome treated with oral cyclosporine
J Family Med Prim Care. 2023 Dec;12(12):3425-3428. doi: 10.4103/jfmpc.jfmpc_1162_23. Epub 2023 Dec 21.ABSTRACTStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin inhibitor, has been reported to have a promising therapeutic effect in SJS/TEN patients with few side effects. Diagnosis of SJS/TEN in children is especially challenging as many of the symptoms mimic that of an upper respi...
Source: Primary Care - February 16, 2024 Category: Primary Care Authors: Victoria Griffith Amanda Ramnot Sydney R Resnik Barry I Resnik Source Type: research
A case of Stevens-Johnson syndrome treated with oral cyclosporine
J Family Med Prim Care. 2023 Dec;12(12):3425-3428. doi: 10.4103/jfmpc.jfmpc_1162_23. Epub 2023 Dec 21.ABSTRACTStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin inhibitor, has been reported to have a promising therapeutic effect in SJS/TEN patients with few side effects. Diagnosis of SJS/TEN in children is especially challenging as many of the symptoms mimic that of an upper respi...
Source: Herpes - February 16, 2024 Category: Infectious Diseases Authors: Victoria Griffith Amanda Ramnot Sydney R Resnik Barry I Resnik Source Type: research
Clinical and Laboratory Diagnosis of Exanthems Among Japanese Children Younger Than 6 Years Old in the Post-Measles-Rubella Vaccine Era
CONCLUSIONS: The most common causes of pediatric exanthems were noninfectious diseases and viral exanthema. PCR assay was instrumental for etiological diagnosis of nonspecific exanthems.PMID:37963264 | DOI:10.1097/INF.0000000000004175 (Source: Herpes)
Source: Herpes - November 14, 2023 Category: Infectious Diseases Authors: Masato Yasuda Kensuke Shoji Keiichi Tomita Yoshiko Uchida Satoko Uematsu Kazue Yoshida Naoko Kono Motoki Funatsu Isao Miyairi Source Type: research
Clinical and Laboratory Diagnosis of Exanthems Among Japanese Children Younger Than 6 Years Old in the Post-Measles-Rubella Vaccine Era
CONCLUSIONS: The most common causes of pediatric exanthems were noninfectious diseases and viral exanthema. PCR assay was instrumental for etiological diagnosis of nonspecific exanthems.PMID:37963264 | DOI:10.1097/INF.0000000000004175 (Source: Herpes)
Source: Herpes - November 14, 2023 Category: Infectious Diseases Authors: Masato Yasuda Kensuke Shoji Keiichi Tomita Yoshiko Uchida Satoko Uematsu Kazue Yoshida Naoko Kono Motoki Funatsu Isao Miyairi Source Type: research
Worldwide Evolution of Vaccinable and Nonvaccinable Viral Skin Infections: Google Trends Analysis
CONCLUSIONS: Harnessing data generated by web searches may increase the efficacy of traditional surveillance systems and strengthens the suspicion that the incidence of some vaccinable viral skin infections such as varicella, measles, and rubella may be globally increasing, whereas the incidence of common nonvaccinable skin infections remains stable.PMID:37632891 | DOI:10.2196/35034 (Source: Herpes)
Source: Herpes - August 26, 2023 Category: Infectious Diseases Authors: Thierry Simonart Xu ân-Lan Lam Hoai Viviane de Maertelaer Source Type: research
Case report: Acute liver failure in children and the human herpes virus 6-? A factor in the recent epidemic
We report on the historic cases of three female infants who had suspected primary HHV-6B infection, acute hepatitis and rapid progression to acute liver failure (ALF) requiring LT. Appearances of their native liver were identical to those described in children in the recent hepatitis epidemic. Deteriorating clinical trajectories of recurrent graft hepatitis and rejection-like episodes followed and all three succumbed to graft failure with HHV-6B detected posthumously in their liver allografts. Our case series and the serious complications observed with the recent rise in common childhood infections is a reminder that these...
Source: Herpes - May 14, 2023 Category: Infectious Diseases Authors: Suz Warner Rachel M Brown Gary M Reynolds Zania Stamataki Deirdre A Kelly Source Type: research
Case report: Acute liver failure in children and the human herpes virus 6-? A factor in the recent epidemic
We report on the historic cases of three female infants who had suspected primary HHV-6B infection, acute hepatitis and rapid progression to acute liver failure (ALF) requiring LT. Appearances of their native liver were identical to those described in children in the recent hepatitis epidemic. Deteriorating clinical trajectories of recurrent graft hepatitis and rejection-like episodes followed and all three succumbed to graft failure with HHV-6B detected posthumously in their liver allografts. Our case series and the serious complications observed with the recent rise in common childhood infections is a reminder that these...
Source: Herpes - May 14, 2023 Category: Infectious Diseases Authors: Suz Warner Rachel M Brown Gary M Reynolds Zania Stamataki Deirdre A Kelly Source Type: research
Neurological Presentation in Roseola Infantum is Seldom Encephalitis in Immunocompetent Children
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 18, 2022 Category: Pediatrics Source Type: research
Human herpes simplex virus-6 (HHV-6) detection and seroprevalence among Qatari nationals and immigrants residing in Qatar
CONCLUSION: The seroprevalence of HHV-6 in Qatar was found to be similar to rates reported in other parts of the world.PMID:35757074 | PMC:PMC9216376 | DOI:10.1016/j.ijregi.2021.12.005 (Source: Herpes)
Source: Herpes - June 27, 2022 Category: Infectious Diseases Authors: Duaa W Al-Sadeq Hadeel T Zedan Nader Aldewik Alaa Elkhider Asalet Hicazi Nadin Younes Houssein H Ayoub Laith Abu Raddad Hadi M Yassine Gheyath K Nasrallah Source Type: research
Human herpes simplex virus-6 (HHV-6) detection and seroprevalence among Qatari nationals and immigrants residing in Qatar
CONCLUSION: The seroprevalence of HHV-6 in Qatar was found to be similar to rates reported in other parts of the world.PMID:35757074 | PMC:PMC9216376 | DOI:10.1016/j.ijregi.2021.12.005 (Source: Herpes)
Source: Herpes - June 27, 2022 Category: Infectious Diseases Authors: Duaa W Al-Sadeq Hadeel T Zedan Nader Aldewik Alaa Elkhider Asalet Hicazi Nadin Younes Houssein H Ayoub Laith Abu Raddad Hadi M Yassine Gheyath K Nasrallah Source Type: research
< em > Microvirga roseola < /em > sp. nov. and < em > Microvirga lenta < /em > sp. nov., isolated from Taklamakan Desert soil
Int J Syst Evol Microbiol. 2022 Jun;72(6). doi: 10.1099/ijsem.0.005409.ABSTRACTTwo Gram-negative, rod-shaped, non-spore-forming bacteria, designated SM9T and SM2T, were isolated from Taklamakan Desert soil samples. Phylogenetic analysis based on the 16S rRNA gene sequences showed that strains SM9T and SM2T had the highest sequence similarity to the type strains Microvirga indica BCRC 80972T and Microvirga soli NBRC 112417T with similarity values of 98.2 and 97.7 %, respectively, and Microvirga was among the predominant genera in the desert soil. The draft genomes of these two strains were 4.56 Mbp (SM9T) and 5.08 Mbp (SM2T...
Source: International Journal of Systematic and Evolutionary Microbiology - June 6, 2022 Category: Microbiology Authors: Xinran Du Qi Ran Jianing Wang Hong Jiang Jingjing Wang Yue-Zhong Li Source Type: research
