Human herpesvirus 6 myelitis after chimeric antigen receptor T-cell therapy

This article reports a fatal case of HHV-6 myelitis with quadriplegia after anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, highlighting an at-risk population for HHV-6 central nervous system (CNS) infection that has not been described previously.

Source: International Journal of Infectious Diseases - September 28, 2021 Category: Infectious Diseases Authors: Guy Handley, Fareed Khawaja, Divya S. Kondapi, Hun J. Lee, Gregory P. Kaufman, Sattva S. Neelapu, Luis E. Fayad, Sudhakar Tummala, Linda Chi, Paolo Strati, Victor E. Mulanovich Source Type: research