A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders
Curr Drug Targets. 2023 Aug 18. doi: 10.2174/1389450124666230818092506. Online ahead of print.ABSTRACTBrain-related disorders are one of the world's most important and complex health problems today. These brain-related disorders are responsible for a massive number of morbidities and death all around the world. However, researchers have devoted a large amount of time to investigating these diseases and found positive results; nevertheless, there are currently quite a few medications available to treat them. Emodin (EM), a polyphenol compound, has many health benefits. It is a biologically active monomer derived from rhubar...
Source: Epilepsy Curr - August 18, 2023 Category: Neurology Authors: Ahsas Goyal Yogesh Murti Bharat Bhushan Wasim Chisti Ashutosh Solanki Source Type: research
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders
Curr Drug Targets. 2023 Aug 18. doi: 10.2174/1389450124666230818092506. Online ahead of print.ABSTRACTBrain-related disorders are one of the world's most important and complex health problems today. These brain-related disorders are responsible for a massive number of morbidities and death all around the world. However, researchers have devoted a large amount of time to investigating these diseases and found positive results; nevertheless, there are currently quite a few medications available to treat them. Emodin (EM), a polyphenol compound, has many health benefits. It is a biologically active monomer derived from rhubar...
Source: Epilepsy Curr - August 18, 2023 Category: Neurology Authors: Ahsas Goyal Yogesh Murti Bharat Bhushan Wasim Chisti Ashutosh Solanki Source Type: research
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders
Curr Drug Targets. 2023 Aug 18. doi: 10.2174/1389450124666230818092506. Online ahead of print.ABSTRACTBrain-related disorders are one of the world's most important and complex health problems today. These brain-related disorders are responsible for a massive number of morbidities and death all around the world. However, researchers have devoted a large amount of time to investigating these diseases and found positive results; nevertheless, there are currently quite a few medications available to treat them. Emodin (EM), a polyphenol compound, has many health benefits. It is a biologically active monomer derived from rhubar...
Source: Epilepsy Curr - August 18, 2023 Category: Neurology Authors: Ahsas Goyal Yogesh Murti Bharat Bhushan Wasim Chisti Ashutosh Solanki Source Type: research
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders
Curr Drug Targets. 2023 Aug 18. doi: 10.2174/1389450124666230818092506. Online ahead of print.ABSTRACTBrain-related disorders are one of the world's most important and complex health problems today. These brain-related disorders are responsible for a massive number of morbidities and death all around the world. However, researchers have devoted a large amount of time to investigating these diseases and found positive results; nevertheless, there are currently quite a few medications available to treat them. Emodin (EM), a polyphenol compound, has many health benefits. It is a biologically active monomer derived from rhubar...
Source: Epilepsy Curr - August 18, 2023 Category: Neurology Authors: Ahsas Goyal Yogesh Murti Bharat Bhushan Wasim Chisti Ashutosh Solanki Source Type: research
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders
Curr Drug Targets. 2023 Aug 18. doi: 10.2174/1389450124666230818092506. Online ahead of print.ABSTRACTBrain-related disorders are one of the world's most important and complex health problems today. These brain-related disorders are responsible for a massive number of morbidities and death all around the world. However, researchers have devoted a large amount of time to investigating these diseases and found positive results; nevertheless, there are currently quite a few medications available to treat them. Emodin (EM), a polyphenol compound, has many health benefits. It is a biologically active monomer derived from rhubar...
Source: Epilepsy Curr - August 18, 2023 Category: Neurology Authors: Ahsas Goyal Yogesh Murti Bharat Bhushan Wasim Chisti Ashutosh Solanki Source Type: research
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders
Curr Drug Targets. 2023 Aug 18. doi: 10.2174/1389450124666230818092506. Online ahead of print.ABSTRACTBrain-related disorders are one of the world's most important and complex health problems today. These brain-related disorders are responsible for a massive number of morbidities and death all around the world. However, researchers have devoted a large amount of time to investigating these diseases and found positive results; nevertheless, there are currently quite a few medications available to treat them. Emodin (EM), a polyphenol compound, has many health benefits. It is a biologically active monomer derived from rhubar...
Source: Epilepsy Curr - August 18, 2023 Category: Neurology Authors: Ahsas Goyal Yogesh Murti Bharat Bhushan Wasim Chisti Ashutosh Solanki Source Type: research
Anti-inflammatory and antioxidant actions of extracts from Rheum rhaponticum and Rheum rhabarbarum in human blood plasma and cells in vitro
Biomed Pharmacother. 2023 Jul 6;165:115111. doi: 10.1016/j.biopha.2023.115111. Online ahead of print.ABSTRACTRheum rhaponticum L. (rhapontic rhubarb) and Rheum rhabarbarum L. (garden rhubarb) are edible and medicinal rhubarb species used for many centuries in traditional medicine. This work is focused on the biological activity of extracts from petioles and roots of R. rhaponticum and R. rhabarbarum as well as rhapontigenin and rhaponticin, typical stilbenes present in these rhubarbs, in a context of their effects on blood physiology and cardiovascular health. Anti-inflammatory properties of the examined substances were ev...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 8, 2023 Category: Drugs & Pharmacology Authors: Oleksandra Liudvytska Magdalena Bandyszewska Tomasz Skirecki Justyna Krzy żanowska-Kowalczyk Mariusz Kowalczyk Joanna Kolodziejczyk-Czepas Source Type: research
Anti-inflammatory and antioxidant actions of extracts from Rheum rhaponticum and Rheum rhabarbarum in human blood plasma and cells in vitro
Biomed Pharmacother. 2023 Jul 6;165:115111. doi: 10.1016/j.biopha.2023.115111. Online ahead of print.ABSTRACTRheum rhaponticum L. (rhapontic rhubarb) and Rheum rhabarbarum L. (garden rhubarb) are edible and medicinal rhubarb species used for many centuries in traditional medicine. This work is focused on the biological activity of extracts from petioles and roots of R. rhaponticum and R. rhabarbarum as well as rhapontigenin and rhaponticin, typical stilbenes present in these rhubarbs, in a context of their effects on blood physiology and cardiovascular health. Anti-inflammatory properties of the examined substances were ev...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 8, 2023 Category: Drugs & Pharmacology Authors: Oleksandra Liudvytska Magdalena Bandyszewska Tomasz Skirecki Justyna Krzy żanowska-Kowalczyk Mariusz Kowalczyk Joanna Kolodziejczyk-Czepas Source Type: research
Rhubarb polysaccharide and berberine co-assembled nanoparticles ameliorate ulcerative colitis by regulating the intestinal flora
Discussion: This design provides a better strategy and encourages future studies on IBD treatment via regulating gut microbiota and the design of novel plant polysaccharide based carrier-free co-assembly therapies. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - June 20, 2023 Category: Drugs & Pharmacology Source Type: research
Rhein protects retinal M üller cells from high glucose-induced injury via activating the AMPK/Sirt1/PGC-1α pathway
In conclusion, these findings support that Rhein may ameliorate HG-induced inflammation, oxidative stress, apoptosis and protect against mitochondrial dysfunction by the activation of the AMPK/Sirt1/PGC-1α signaling pathway.PMID:37330920 | DOI:10.1080/10799893.2023.2223319 (Source: Cell Research)
Source: Cell Research - June 18, 2023 Category: Cytology Authors: Cong Liu Qian Cao Yueqin Chen Xi Chen Yujie Zhu Zhonghua Zhang Wei Wei Source Type: research
Network pharmacology and molecular docking reveal the immunomodulatory mechanism of rhubarb peony decoction for the treatment of ulcerative colitis and irritable bowel syndrome
Conclusion: RPD may exert the overall treatment effect for UC and IBS overlap syndrome via the biological mechanism of "multi-ingredients, multi-targets, and multi-pathways" on inflammation, oxidative stress, immune, oncogenicity, and gut microbiota dysbiosis.PMID:37305432 | PMC:PMC10248730 | DOI:10.3389/jpps.2023.11225 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - June 12, 2023 Category: Drugs & Pharmacology Authors: Leilei Zhai Weiming Yang Dianrong Li Wei Zhou Min Cui Ping Yao Source Type: research
Network pharmacology and molecular docking reveal the immunomodulatory mechanism of rhubarb peony decoction for the treatment of ulcerative colitis and irritable bowel syndrome
Conclusion: RPD may exert the overall treatment effect for UC and IBS overlap syndrome via the biological mechanism of "multi-ingredients, multi-targets, and multi-pathways" on inflammation, oxidative stress, immune, oncogenicity, and gut microbiota dysbiosis.PMID:37305432 | PMC:PMC10248730 | DOI:10.3389/jpps.2023.11225 (Source: Journal of Pharmacy and Pharmaceutical Sciences)
Source: Journal of Pharmacy and Pharmaceutical Sciences - June 12, 2023 Category: Drugs & Pharmacology Authors: Leilei Zhai Weiming Yang Dianrong Li Wei Zhou Min Cui Ping Yao Source Type: research
Network pharmacology and molecular docking reveal the immunomodulatory mechanism of rhubarb peony decoction for the treatment of ulcerative colitis and irritable bowel syndrome
Conclusion: RPD may exert the overall treatment effect for UC and IBS overlap syndrome via the biological mechanism of "multi-ingredients, multi-targets, and multi-pathways" on inflammation, oxidative stress, immune, oncogenicity, and gut microbiota dysbiosis.PMID:37305432 | PMC:PMC10248730 | DOI:10.3389/jpps.2023.11225 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - June 12, 2023 Category: Drugs & Pharmacology Authors: Leilei Zhai Weiming Yang Dianrong Li Wei Zhou Min Cui Ping Yao Source Type: research
Network pharmacology and molecular docking reveal the immunomodulatory mechanism of rhubarb peony decoction for the treatment of ulcerative colitis and irritable bowel syndrome
Conclusion: RPD may exert the overall treatment effect for UC and IBS overlap syndrome via the biological mechanism of "multi-ingredients, multi-targets, and multi-pathways" on inflammation, oxidative stress, immune, oncogenicity, and gut microbiota dysbiosis.PMID:37305432 | PMC:PMC10248730 | DOI:10.3389/jpps.2023.11225 (Source: Journal of Pharmacy and Pharmaceutical Sciences)
Source: Journal of Pharmacy and Pharmaceutical Sciences - June 12, 2023 Category: Drugs & Pharmacology Authors: Leilei Zhai Weiming Yang Dianrong Li Wei Zhou Min Cui Ping Yao Source Type: research
Network pharmacology and molecular docking reveal the immunomodulatory mechanism of rhubarb peony decoction for the treatment of ulcerative colitis and irritable bowel syndrome
Conclusion: RPD may exert the overall treatment effect for UC and IBS overlap syndrome via the biological mechanism of "multi-ingredients, multi-targets, and multi-pathways" on inflammation, oxidative stress, immune, oncogenicity, and gut microbiota dysbiosis.PMID:37305432 | PMC:PMC10248730 | DOI:10.3389/jpps.2023.11225 (Source: J Pharm Pharm Sci)
Source: J Pharm Pharm Sci - June 12, 2023 Category: Drugs & Pharmacology Authors: Leilei Zhai Weiming Yang Dianrong Li Wei Zhou Min Cui Ping Yao Source Type: research
