Rhein protects retinal M üller cells from high glucose-induced injury via activating the AMPK/Sirt1/PGC-1α pathway

In conclusion, these findings support that Rhein may ameliorate HG-induced inflammation, oxidative stress, apoptosis and protect against mitochondrial dysfunction by the activation of the AMPK/Sirt1/PGC-1α signaling pathway.PMID:37330920 | DOI:10.1080/10799893.2023.2223319

Source: Cell Research - June 18, 2023 Category: Cytology Authors: Cong Liu Qian Cao Yueqin Chen Xi Chen Yujie Zhu Zhonghua Zhang Wei Wei Source Type: research