Use of Transcriptome Sequencing to Analyze the Effects of Different Doses of an Astragalus-Rhubarb-Saffron Mixture in Mice with Diabetic Kidney Disease
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 18, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
A chromosome-level genome reveals genome evolution and molecular basis of anthraquinone biosynthesis in Rheum palmatum
Rhubarb is one of common traditional Chinese medicine with a diverse array of therapeutic efficacies. Despite its widespread use, molecular research into rhubarb remains limited, constraining our comprehension... (Source: BMC Plant Biology)
Source: BMC Plant Biology - April 10, 2024 Category: Biology Authors: Tianyi Zhang, Lipan Zhou, Yang Pu, Yadi Tang, Jie Liu, Li Yang, Tao Zhou, Li Feng and Xumei Wang Tags: Research Source Type: research
Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study
CONCLUSION: Emo intervention mitigates bone loss and cartilage damage in OP-OA rats and promotes the osteogenic and chondrogenic differentiation of BMSCs.PMID:38570055 | DOI:10.1016/j.exger.2024.112413 (Source: Experimental Gerontology)
Source: Experimental Gerontology - April 3, 2024 Category: Geriatrics Authors: Yibao Wei Junfeng Kang Zhenyuan Ma Taiyang Liao Peng Wu Peimin Wang Zhengquan Huang Source Type: research
Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study
CONCLUSION: Emo intervention mitigates bone loss and cartilage damage in OP-OA rats and promotes the osteogenic and chondrogenic differentiation of BMSCs.PMID:38570055 | DOI:10.1016/j.exger.2024.112413 (Source: Experimental Gerontology)
Source: Experimental Gerontology - April 3, 2024 Category: Geriatrics Authors: Yibao Wei Junfeng Kang Zhenyuan Ma Taiyang Liao Peng Wu Peimin Wang Zhengquan Huang Source Type: research
Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study
CONCLUSION: Emo intervention mitigates bone loss and cartilage damage in OP-OA rats and promotes the osteogenic and chondrogenic differentiation of BMSCs.PMID:38570055 | DOI:10.1016/j.exger.2024.112413 (Source: Experimental Gerontology)
Source: Experimental Gerontology - April 3, 2024 Category: Geriatrics Authors: Yibao Wei Junfeng Kang Zhenyuan Ma Taiyang Liao Peng Wu Peimin Wang Zhengquan Huang Source Type: research
Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study
CONCLUSION: Emo intervention mitigates bone loss and cartilage damage in OP-OA rats and promotes the osteogenic and chondrogenic differentiation of BMSCs.PMID:38570055 | DOI:10.1016/j.exger.2024.112413 (Source: Experimental Gerontology)
Source: Experimental Gerontology - April 3, 2024 Category: Geriatrics Authors: Yibao Wei Junfeng Kang Zhenyuan Ma Taiyang Liao Peng Wu Peimin Wang Zhengquan Huang Source Type: research
Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study
CONCLUSION: Emo intervention mitigates bone loss and cartilage damage in OP-OA rats and promotes the osteogenic and chondrogenic differentiation of BMSCs.PMID:38570055 | DOI:10.1016/j.exger.2024.112413 (Source: Experimental Gerontology)
Source: Experimental Gerontology - April 3, 2024 Category: Geriatrics Authors: Yibao Wei Junfeng Kang Zhenyuan Ma Taiyang Liao Peng Wu Peimin Wang Zhengquan Huang Source Type: research
The Role of Emodin in the Treatment of Bladder Cancer based on Network Pharmacology and Experimental Verification
CONCLUSION: This study integrates network pharmacology with in vitro experimentation to elucidate the potential mechanisms underlying the action of Emodin against BLCA. The results of this research enhance our understanding of the pharmacological mechanisms by which Emodin may be employed in treating BLCA.PMID:38504574 | DOI:10.2174/0113862073294990240122140121 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - March 20, 2024 Category: Chemistry Authors: Fule Liu Jianghao Li Boruo Zhou Yang Shen Jingyuan Tang Jie Han Changpeng Chen Kang Shao Haojie Chen Lin Yuan Source Type: research
The Role of Emodin in the Treatment of Bladder Cancer based on Network Pharmacology and Experimental Verification
CONCLUSION: This study integrates network pharmacology with in vitro experimentation to elucidate the potential mechanisms underlying the action of Emodin against BLCA. The results of this research enhance our understanding of the pharmacological mechanisms by which Emodin may be employed in treating BLCA.PMID:38504574 | DOI:10.2174/0113862073294990240122140121 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - March 20, 2024 Category: Chemistry Authors: Fule Liu Jianghao Li Boruo Zhou Yang Shen Jingyuan Tang Jie Han Changpeng Chen Kang Shao Haojie Chen Lin Yuan Source Type: research
The Role of Emodin in the Treatment of Bladder Cancer based on Network Pharmacology and Experimental Verification
CONCLUSION: This study integrates network pharmacology with in vitro experimentation to elucidate the potential mechanisms underlying the action of Emodin against BLCA. The results of this research enhance our understanding of the pharmacological mechanisms by which Emodin may be employed in treating BLCA.PMID:38504574 | DOI:10.2174/0113862073294990240122140121 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - March 20, 2024 Category: Chemistry Authors: Fule Liu Jianghao Li Boruo Zhou Yang Shen Jingyuan Tang Jie Han Changpeng Chen Kang Shao Haojie Chen Lin Yuan Source Type: research
The Role of Emodin in the Treatment of Bladder Cancer based on Network Pharmacology and Experimental Verification
CONCLUSION: This study integrates network pharmacology with in vitro experimentation to elucidate the potential mechanisms underlying the action of Emodin against BLCA. The results of this research enhance our understanding of the pharmacological mechanisms by which Emodin may be employed in treating BLCA.PMID:38504574 | DOI:10.2174/0113862073294990240122140121 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - March 20, 2024 Category: Chemistry Authors: Fule Liu Jianghao Li Boruo Zhou Yang Shen Jingyuan Tang Jie Han Changpeng Chen Kang Shao Haojie Chen Lin Yuan Source Type: research
Photocatalytic degradation of tetracycline using a novel WO3-ZnO/AC under visible light irradiation: Optimization of effective factors by RSM-CCD
Environ Pollut. 2024 Mar 7;347:123746. doi: 10.1016/j.envpol.2024.123746. Online ahead of print.ABSTRACTMitigating pharmaceutical pollution in the global environment is imperative, and tetracycline (TC) is a commonly utilized antibiotic in human and veterinary medicine. The persistent existence of TC highlights the necessity of establishing efficient measures to protect water systems and the environment from detrimental contaminants. Herein, a novel rhubarb seed waste-derived activated carbon-supported photocatalyst (WO3-ZnO/RUAC) was synthesized by combining wet impregnation and ultrasonic methods. The activated carbon (A...
Source: Environmental Pollution - March 9, 2024 Category: Environmental Health Authors: Mohammad Sina Mohtaram Samad Sabbaghi Jamal Rasouli Kamal Rasouli Source Type: research
Transcriptomic divergence of the Rheum palmatum complex derived from top-geoherb and non-geoherb areas provides the insights into geoherbalism properties of rhubarb
Geoherb usually represents high-quality medicinal herbs with better clinical therapeutic effects, and elucidating the geoherbalism is essential for the quality improvement of traditional Chinese Medicine. Howe... (Source: BMC Genomics)
Source: BMC Genomics - February 26, 2024 Category: Genetics & Stem Cells Authors: Tao Zhou, Yadi Tang, Lipan Zhou, Jie Liu, Yang Pu, Fan Jiang, Jian Wang and Xumei Wang Tags: Research Source Type: research
Topical rhubarb charcoal-crosslinked chitosan/silk fibroin sponge scaffold for the repair of diabetic ulcers improves hepatic lipid deposition in db/db mice via the AMPK signalling pathway
Type 2 diabetes mellitus (T2DM) is closely linked to metabolic syndrome, characterised by insulin resistance, hyperglycaemia, abnormal lipid metabolism, and chronic inflammation. Diabetic ulcers (DUs) comprise... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - February 20, 2024 Category: Lipidology Authors: Qi Tan, Qifeng He, Ze Peng, Xin Zeng, Yuzhe Liu, Dong Li, Shang Wang and Jianwei Wang Tags: Research Source Type: research
Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF- β1 and p38-MAPK/smad2/3 pathways
CONCLUSIONS: Rhubarb-Astragalus improves CKD possibly by downregulating autophagy via the p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways.PMID:38340950 | DOI:10.1016/j.biocel.2024.106549 (Source: The International Journal of Biochemistry and Cell Biology)
Source: The International Journal of Biochemistry and Cell Biology - February 10, 2024 Category: Biochemistry Authors: Jinxiu Li Xiping Qin Weimin Xu Hongliang Zhang Songqing Huang Yufang Yang Mengyuan Qin Zhengcheng Mi Xiaobin Zhong Source Type: research
