Audiology evaluation following intra-arterial carboplatin for retinoblastoma
Can J Ophthalmol. 2024 Feb 16:S0008-4182(24)00030-9. doi: 10.1016/j.jcjo.2024.01.014. Online ahead of print.NO ABSTRACTPMID:38373698 | DOI:10.1016/j.jcjo.2024.01.014 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - February 19, 2024 Category: Opthalmology Authors: Aurora Rodriguez Todd Abruzzo James A Williams Aparna Ramasubramanian Source Type: research
Audiology evaluation following intra-arterial carboplatin for retinoblastoma
Can J Ophthalmol. 2024 Feb 16:S0008-4182(24)00030-9. doi: 10.1016/j.jcjo.2024.01.014. Online ahead of print.NO ABSTRACTPMID:38373698 | DOI:10.1016/j.jcjo.2024.01.014 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - February 19, 2024 Category: Opthalmology Authors: Aurora Rodriguez Todd Abruzzo James A Williams Aparna Ramasubramanian Source Type: research
Advancements in the diagnosis, prognosis, and treatment of retinoblastoma
Can J Ophthalmol. 2024 Feb 15:S0008-4182(24)00031-0. doi: 10.1016/j.jcjo.2024.01.018. Online ahead of print.ABSTRACTRetinoblastoma (RB) is a prevalent primitive intraocular malignancy in children, particularly in those younger than age 3 years. RB is caused by mutations in the RB1 gene. In developing countries, mortality rates for this type of cancer are still high, whereas industrialized countries have achieved a survival rate of >95%-98%. Untreated, the condition can be fatal, underscoring the importance of early diagnosis. The existing treatments primarily consist of surgery, radiotherapy, and chemotherapy. The detri...
Source: Canadian Journal of Ophthalmology - February 18, 2024 Category: Opthalmology Authors: Shivam Rajput Rishabha Malviya Prerna Uniyal Source Type: research
Advancements in the diagnosis, prognosis, and treatment of retinoblastoma
Can J Ophthalmol. 2024 Feb 15:S0008-4182(24)00031-0. doi: 10.1016/j.jcjo.2024.01.018. Online ahead of print.ABSTRACTRetinoblastoma (RB) is a prevalent primitive intraocular malignancy in children, particularly in those younger than age 3 years. RB is caused by mutations in the RB1 gene. In developing countries, mortality rates for this type of cancer are still high, whereas industrialized countries have achieved a survival rate of >95%-98%. Untreated, the condition can be fatal, underscoring the importance of early diagnosis. The existing treatments primarily consist of surgery, radiotherapy, and chemotherapy. The detri...
Source: Canadian Journal of Ophthalmology - February 18, 2024 Category: Opthalmology Authors: Shivam Rajput Rishabha Malviya Prerna Uniyal Source Type: research
Cancers, Vol. 16, Pages 805: Tissue-Based Diagnostic Biomarkers of Aggressive Variant Prostate Cancer: A Narrative Review
Tzelepi
Prostate cancer (PC) is a common malignancy among elderly men, characterized by great heterogeneity in its clinical course, ranging from an indolent to a highly aggressive disease. The aggressive variant of prostate cancer (AVPC) clinically shows an atypical pattern of disease progression, similar to that of small cell PC (SCPC), and also shares the chemo-responsiveness of SCPC. The term AVPC does not describe a specific histologic subtype of PC but rather the group of tumors that, irrespective of morphology, show an aggressive clinical course, dictated by androgen receptor (AR) indifference. AR indifference re...
Source: Cancers - February 16, 2024 Category: Cancer & Oncology Authors: Olga Kouroukli Vasiliki Bravou Konstantinos Giannitsas Vasiliki Tzelepi Tags: Review Source Type: research
Pigmented medulloepithelioma of the optic nerve: A challenging diagnostic entity
Indian J Pathol Microbiol. 2024 Jan-Mar;67(1):207-210. doi: 10.4103/ijpm.ijpm_116_22.ABSTRACTBecause of its rarity, the diagnosis of optic nerve medulloepithelioma poses a real diagnostic challenge. Medulloepithelioma is a congenital tumor that derives from the primitive medullary epithelium present in the neural tube and the optic vesicle. Its classical location is the ciliary body. Cases of retinal or optic nerve locations have been rarely reported in the literature. Only 11 cases have been published in the English literature. Herein, we report the case of a 2-year-old boy who underwent enucleation of the right eye for a...
Source: Indian Journal of Pathology and Microbiology - February 15, 2024 Category: Pathology Authors: Tiabi El Mehdi Chariba Siham Kamaoui Imane Benajiba Noufissa Bennani Amal Source Type: research
Pigmented medulloepithelioma of the optic nerve: A challenging diagnostic entity
Indian J Pathol Microbiol. 2024 Jan-Mar;67(1):207-210. doi: 10.4103/ijpm.ijpm_116_22.ABSTRACTBecause of its rarity, the diagnosis of optic nerve medulloepithelioma poses a real diagnostic challenge. Medulloepithelioma is a congenital tumor that derives from the primitive medullary epithelium present in the neural tube and the optic vesicle. Its classical location is the ciliary body. Cases of retinal or optic nerve locations have been rarely reported in the literature. Only 11 cases have been published in the English literature. Herein, we report the case of a 2-year-old boy who underwent enucleation of the right eye for a...
Source: Indian Journal of Pathology and Microbiology - February 15, 2024 Category: Pathology Authors: Tiabi El Mehdi Chariba Siham Kamaoui Imane Benajiba Noufissa Bennani Amal Source Type: research
Automated detection of nine infantile fundus diseases and conditions in retinal images using a deep learning system
ConclusionsIRIDS identifies nine infantile fundus diseases and conditions accurately. It may aid non-ophthalmologist personnel in underserved areas in infantile fundus disease screening. Thus, preventing severe complications. The IRIDS serves as an example of artificial intelligence integration into ophthalmology to achieve better outcomes in predictive, preventive, and personalized medicine (PPPM / 3PM) in the treatment of infantile fundus diseases. (Source: EPMA Journal)
Source: EPMA Journal - February 15, 2024 Category: International Medicine & Public Health Source Type: research
Impact of RB1 gene screening from blood collected on a single day from 411 family members of 113 Retinoblastoma survivors in India
Eye, Published online: 10 February 2024; doi:10.1038/s41433-024-02955-zImpact of RB1 gene screening from blood collected on a single day from 411 family members of 113 Retinoblastoma survivors in India (Source: Eye)
Source: Eye - February 10, 2024 Category: Opthalmology Authors: Ayyasamy Vanniarajan Puja Maitra Karuvel Kannan Saraswathi Parag K. Shah Source Type: research
Orbital Development in Children with Retinoblastoma: An Imaging-Based Study
CONCLUSIONS: Orbital growth rate is slower in the orbits of children treated for Rb compared to healthy orbits. Enucleation negatively affects orbital growth.PMID:38329101 | DOI:10.1080/08820538.2024.2312968 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - February 8, 2024 Category: Opthalmology Authors: Shir Forer Guy J Ben Simon Gahl Greenberg Lital Smadar Amit Zabatani Mattan Arazi Ido Didi Fabian Vicktoria Vishnevskia-Dai Daphna Landau-Prat Source Type: research
Comparison of HASTE versus EPI-Based DWI for Retinoblastoma and Correlation with Prognostic Histopathologic Parameters [HEAD AND NECK IMAGING]
CONCLUSIONS:
HASTE-DWI shows improved overall image quality; however, it lacks in terms of tumor conspicuity, SNR, CNR, and longer acquisition time compared with EPI-DWI. ADC values derived from HASTE-DWI show no advantage over EPI-DWI in correlation with histopathologic prognostic markers. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - February 7, 2024 Category: Radiology Authors: Sharma, M., Gupta, A., Jana, M., Kashyap, S., Bakhshi, S., Sharma, S. Tags: HEAD AND NECK IMAGING Source Type: research
Pediatric orbital lesions: ocular pathologies
AbstractOrbital pathologies can be broadly classified as ocular, extra-ocular soft-tissue (non-neoplastic and neoplastic), osseous, and traumatic. In part 1 of this orbital series, the authors will discuss the differential diagnosis and key imaging features of pediatric ocular pathologies. These include congenital and developmental lesions (microphthalmos, anophthalmos, persistent fetal vasculature, coloboma, morning glory disc anomaly, retinopathy of prematurity, Coats disease), optic disc drusen, infective and inflammatory lesions (uveitis, toxocariasis, toxoplasmosis), and ocular neoplasms (retinoblastoma, retinal hamar...
Source: Pediatric Radiology - February 7, 2024 Category: Radiology Source Type: research
Newly Recognized Genetic Tumor Syndromes of the CNS in the 5th WHO Classification: Imaging Overview with Genetic Updates [BRAIN TUMOR IMAGING]
SUMMARY:
The nervous system is commonly involved in a wide range of genetic tumor-predisposition syndromes. The classification of genetic tumor syndromes has evolved during the past years; however, it has now become clear that these syndromes can be categorized into a relatively small number of major mechanisms, which form the basis of the new 5th edition of the World Health Organization book (beta online version) on genetic tumor syndromes. For the first time, the World Health Organization has also included a separate chapter on genetic tumor syndromes in the latest edition of all the multisystem tumor series, including t...
Source: American Journal of Neuroradiology - February 7, 2024 Category: Radiology Authors: Agarwal, A., Bathla, G., Soni, N., Desai, A., Ajmera, P., Rao, D., Gupta, V., Vibhute, P. Tags: BRAIN TUMOR IMAGING Source Type: research
Updated retinoblastoma incidence and outcome in children in Taiwan from 1980 to 2019: a 40-year nationwide study
Eye, Published online: 02 February 2024; doi:10.1038/s41433-024-02946-0Updated retinoblastoma incidence and outcome in children in Taiwan from 1980 to 2019: a 40-year nationwide study (Source: Eye)
Source: Eye - February 2, 2024 Category: Opthalmology Authors: En-Tai Liao Hui-Yun Lin Chia-Ying Tsai Source Type: research
The Traces of Dysregulated lncRNAs-Associated ceRNA Axes in Retinoblastoma: A Systematic Scope Review
CONCLUSIONS: Understanding the many features of this regulatory system may aid in elucidating the unknown etiology of Retinoblastoma and providing novel molecular targets for therapeutic and clinical applications.PMID:38299506 | DOI:10.1080/02713683.2024.2306859 (Source: Current Eye Research)
Source: Current Eye Research - February 1, 2024 Category: Opthalmology Authors: Kourosh Shahraki Amin Najafi Vida Ilkhani Pak Kianoush Shahraki Paria Ghasemi Boroumand Roghayeh Sheervalilou Source Type: research
