Time-Frequency Analysis of Photopic Negative Response in CRVO Patients.
Authors: Behbahani S, Ramezani A, Karimi Moridani M, Sabbaghi H Abstract PURPOSE: The PhNR is driven by retinal ganglion cells (RGCs). Therefore, the function of RGCs could be objectively evaluated by analyzing the PhNR. The aim of this article is to determine the effect of central retinal vein occlusion (CRVO) on PhNR and RGCs performances. METHODS: Seventeen patients with CRVO were included. Full-field photopic ERGs, including PhNR, were recorded and compared with the fellow normal eyes. ERG signals were analyzed based on the standard time-domain analyses of the PhNR as well as a continuous wavelet transform ...
Source: Seminars in Ophthalmology - June 27, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Outcomes of Glaucoma Drainage Devices in Childhood Glaucoma.
CONCLUSION: Various designs of GDDs are available for management of childhood glaucoma with good short-term success rates; individual patient factors should be taken into consideration when selecting a specific device. PMID: 32567448 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - June 24, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

The Effects of Consumer-grade Virtual Reality Headsets on Adult Visual Function.
CONCLUSION: It is discovered that using a consumer-grade VR headset 10 minutes at a time twice daily for 2 weeks improved the amplitude of accommodation of adults dramatically, while neither visual acuity nor refractive error was affected. ABBREVIATIONS: VR: visual reality; UDVA: uncorrected distant visual acuity; UNVA: uncorrected near visual acuity; BCVA: best corrected visual acuity; LCVA: low contrast visual acuity; GVA: glare visual acuity; RE: refractive error; ACC: amplitude of accommodation; PD: pupil diameter; 3D: three-dimensional; VDTS: visual display terminal syndrome; FOV: field of view; SEQ: sph...
Source: Seminars in Ophthalmology - June 24, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Phototherapeutic Keratectomy in Macular and Granular Dystrophy: Two-year Results.
Authors: Kemer Atik B, Yildirim Y, Sonmez O, Gumus G, Kepez Yildiz B, Agca A Abstract PURPOSE: To evaluate two-year outcomes of phototherapeutic keratectomy in granular and macular dystrophy and to investigate the effects of dystrophy type on results. METHODS: Sixty-three patients who underwent phototherapeutic keratectomy (PTK) for granular and macular dystrophy in the cornea funit of the University of Health Sciences Beyoglu Eye Research and Training Hospital were evaluated retrospectively. Patients under 18 years of age, patients with a follow-up period of less than 24 months, and patients who had ...
Source: Seminars in Ophthalmology - June 14, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Vision-Related Quality of Life, Anxiety and Depression in Congolese Patients with Polypoidal Choroidal Vasculopathy.
Authors: Kabedi NN, Kayembe DL, Mwanza JC Abstract OBJECTIVE: To assess the impact of polypoidal choroidal vasculopathy (PCV) on quality of life (QoL) and mental health in a cohort of Congolese patients. METHODS: Fifteen PCV patients and 26 age-matched controls completed the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) and the Hospital Anxiety and Depression Scale (HADS) questionnaire. Outcome measures were QoL and HADS scores, frequency of anxiety and depression, correlations between best-corrected distance visual acuity (BCDVA) and QoL and HADS scores. Risk factors for anxiety and depress...
Source: Seminars in Ophthalmology - June 10, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Molecular Genetics of Intraocular Tumors.
CONCLUSION: Molecular tests are playing an increasingly important role in the diagnosis of intraocular tumors. They provide information valuable for diagnosis, prognosis, screening regimens, genetic counselling, and treatment. These technologies are becoming easier, faster, and with higher sensitivity and accuracy. PMID: 32507011 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - June 10, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

A Clinical Audit on the Predictors for Visual Morbidity in Patients with Beh çet's Disease Attending Cairo University Hospitals.
CONCLUSION: BD is associated with considerable vision loss at a young age. Panuveitis, bilaterality, ocular activity, and interventions are significant predictors. A diagnostic time lag ≥ 9 months is associated with poor visual outcomes and is significantly associated with rural residency. PMID: 32475197 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - June 3, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Biofeedback Low Vision Rehabilitation with Retimax Vision Trainer in Patients with Advanced Age-related Macular Degeneration: A Pilot Study.
CONCLUSIONS: Preliminary results support VEP biofeedback rehabilitation improvements for visual function and quality of life in advanced AMD patients with low vision. PMID: 32476579 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - June 3, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Ocular Hypertension Following Intravitreal Injection of 0.7mg Dexamethasone Implant versus 2mg Triamcinolone.
Conclusions: Rates of ocular hypertension following 2 mg IVT and DEX are similar. All patients developing OHT were successfully managed without surgical intervention. PMID: 32343619 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - April 29, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Clinical Accuracy of an Advanced Corneal Topographer with Tear-Film Analysis in Functional and Structural Evaluation of Dry Eye Disease.
Conclusion: The Antares topographer is useful in the diagnosis of DED. Among its outputs, the NIF-BUT and MG dropout most closely correlated with currently accepted modes of diagnosis. However, concurrent clinical examinations are recommended for clinical follow-up. PMID: 32306802 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - April 22, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Detection of structural and electrical disturbances in macula and optic nerve in Alzheimer's patients and their correlation with disease severity.
Conclusion: Subclinical visual dysfunction may be present in AD patients, which may be detected as inner retinal thinning. A probable photoreceptor abnormality may also form a part of the AD disease process. PMID: 32306804 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - April 22, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Concentrations of Selected Cytokines and Vascular Endothelial Growth Factor in Aqueous Humor and Serum of Diabetic Patients.
Conclusion: Our findings support the hypothesis that chronic inflammation and a disturbance of the immune system play important roles in the pathogenesis of diabetic cataract and DR. PMID: 32310727 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - April 22, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Retraction: Effective Lens Position According to Incision Width in Cataract Surgery Using Phacoemultification and Posterior Chamber Lens Implantation.
Authors: PMID: 32315257 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - April 22, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Multi-parametric magnetic resonance imaging characterization of orbital lesions: A triple-blind study.
Authors: Russo C, Strianese D, Perrotta M, Iuliano A, Bernardo R, Romeo V, Ugga L, Brunetti L, Tranfa F, Elefante A Abstract Background: Multi-parametric MRI used for preoperative assessment of orbital lesions does not routinely include DCE-MRI, since its accuracy in differential diagnosis of orbital mass is still under debate. Aim of this study is to characterize orbital lesions by multi-parametric MRI, analysing the incremental predictive value of DCE-MRI in differential diagnosis of orbital lesions.Methods: In this prospective triple-blind study, 43 consecutive patients with unilateral orbital lesion underwent c...
Source: Seminars in Ophthalmology - April 18, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Binocular, Accommodative and Oculomotor Alterations In Multiple Sclerosis: A Review.
In conclusion, oculomotor impairment is a common component of disability in MS patients and should be considered when managing this type of patients. More research is still needed to know the real impact of this disease on binocular vision and accommodation. PMID: 32228341 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - April 2, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Correlation of Non-invasive Tear Break-Up Time with Tear Osmolarity and Other Invasive Tear Function Tests.
Authors: Ozulken K, Aksoy Aydemir G, Tekin K, Mumcuoğlu T Abstract Aim: To compare the outcomes of non-invasive break-up time (NI-BUT) test and the other conventional dry eye tests.Methods: The right eyes of 170 subjects were included in the study. In order to evaluate the tear quality of the patients, NI-BUT levels were measured by the Scheimplug-Placido disk system (Sirius topography). Tear osmolarity test was performed with TearLab Osmolarity System. Topical anesthesia-assisted type I Schirmer test and topical anesthesia-assisted BUT were lastly applied to all patients in order not to affect other measurements....
Source: Seminars in Ophthalmology - March 19, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Diabetic retinopathy and ultrawide field imaging.
Authors: Ashraf M, Shokrollahi S, Salongcay RP, Aiello LP, Silva PS Abstract The introduction of ultrawide field imaging has allowed the visualization of approximately 82% of the total retinal area compared to only 30% using 7-standard field Early Treatment Diabetic Retinopathy (ETDRS) photography. This substantially wider field of view, while useful in many retinal vascular diseases, is particularly important in diabetic retinopathy where eyes with predominantly peripheral lesions or PPL have been shown to have significantly greater progression rates compared to eyes without PPL. In telemedicine settings, ultrawid...
Source: Seminars in Ophthalmology - March 15, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Surgical outcome of exotropic Duane syndrome.
Authors: Fouad HM, Awadein A, Youssef AA, Saeed H, Shousha SM Abstract Purpose: To evaluate the surgical outcome of exotropic Duane syndrome and the factors that can influence the outcome.Methods: A retrospective study was performed on patients who had surgery for exotropic Duane syndrome with a minimum follow-up of 3 months. The ocular motility, the angles of deviation, the presence of abnormal head turn or overshoots, the surgical procedures performed, and their outcome were analyzed.Results: Sixty-seven patients were identified (mean age, 11.3 years). In unilateral cases with exotropia
Source: Seminars in Ophthalmology - March 6, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Descemet membrane endothelial keratoplasty and intraocular lens implantation in cases of aphakic bullous keratopathy.
Authors: Koçluk Y, Kasım B Abstract Purpose: To present the results of a modified sutured transcleral or sutureless intrascleral three-piece foldable intraocular lens (IOL) implantation with Descemet membrane endothelial keratoplasty (DMEK) in cases of aphakic bullous keratopathy (ABK) with inadequate capsular support.Methods: Twenty-one eyes of 21 patients with ABK and inadequate capsular support who underwent DMEK with three-piece foldable IOL implantation from September 2015 to June 2018 were analyzed, retrospectively. Two techniques were used in IOL implantation; sutureless intrascleral fixation of the ...
Source: Seminars in Ophthalmology - February 28, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Clinical Features of Ocular Syphilis: a Retrospective Clinical Study in an Italian Referral Centre.
Conclusions: The ophthalmologist should suspect syphilis in patien ts with uveitis or optic neuropathy associated with high-risk sexual behaviour and/or HIV, or in patients with posterior placoid chorioretinitis, necrotising retinitis, or interstitial keratitis. PMID: 32036734 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - February 12, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Prevalence of and factors related with abnormal fundoscopic findings among the elderly population in a rural community in South Korea.
Authors: Choi HR, Rim TH, Lee JH, Lee SW, Baek J, Kim K, Youm Y, Kim HC Abstract We aimed to report the results of fundus photography ophthalmic examinations among older adults in a rural community in South Korea. We used data from the Korean Social Life, Health, and Aging Project cohort study, which was designed to examine the entire population of individuals aged 60 years or older and their spouses living in a rural Village K of Ganghwa Island, South Korea. At baseline, a total of 860 people was targeted as the study population. From December 2011 to January 2019, five health examinations were conducted, includin...
Source: Seminars in Ophthalmology - February 8, 2020 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Effect of reduced meal frequency during Ramadan fasting on retinal and choroidal thickness.
Authors: Uzun S, Pehlivan E Abstract This paper is a comment on the article entitled "Effect of reduced meal frequency during Ramadan fasting on retinal and choroidal thickness'' by Ersan et al. We think this paper will make a significant contribution to this article and to the literature. PMID: 31846398 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - December 19, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Amyloidosis and Ocular Involvement: an Overview.
Conclusion: A routine ophthalmic follow-up is recommended for all patients with established or suspected amyloidosis, independent of the biochemical type of the amyloid. Close collaboration between the ophthalmologist and the internist will facilitate a more precise diagnosis of ocular involvement in amyloidosis and allow the multidisciplinary management of these patients.Abbreviations: CD: corneal dystrophy; CLA: corneal lattice amyloidosis; CNS: central nervous system; CT: computed tomography; FAP: familial amyloidotic polyneuropathy; GDLCD: gelatinous drop-like corneal dystrophy; GLN: gelsolin; LCD: lattice corneal dyst...
Source: Seminars in Ophthalmology - December 13, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Results of Switching from Pro Re Nata to Treat-and-Extend Regimen in Treatment of Patients with Type 3 Neovascularization.
Conclusions: In type 3 neovascularization, visual acuity was maintained for an average of 20.5 months after switching from the PRN regimen to the TAE regimen. Further studies with larger study populations and controlled study designs are required to confirm our findings. PMID: 31814497 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - December 10, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Long term motor and sensory outcome after surgery for infantile esotropia and risk factors for residual and consecutive deviations.
Conclusions: Successful motor alignment may be obtained with single surgery in infantile esotropia; however, reoperations are common. Younger age at first surgery may be associated with both higher rate of stereopsis and risk of reoperation. Careful preoperative assessment and surgical timing, with long-term postoperative follow-up is required to achieve satisfactory outcome. PMID: 31739718 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - November 20, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Intravitreal Ziv-Aflibercept : Safety Analysis in Eyes Receiving More Than Ten Intravitreal Injections.
Conclusion: Ocular use of ziv-aflibercept is safe with limited ocular and systemic side effects. Multiple injections of IVZ can be used in various chorioretinal diseases over the long term. PMID: 31690175 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - November 7, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Can Hypothyroidism Cause Acute Central Serous Chorioretinopathy?
Authors: Ulaş F, Uyar E, Tekçe H, Çelebi S Abstract Purpose: To evaluate selected systemic findings, especially thyroid functions, in acute central serous chorioretinopathy (CSC) patients. Materials and Methods: In all, 71 consecutive acute CSC patients who fulfilled the inclusion criteria and 70 age-matched healthy control subjects were included in the study. Systemic findings, including serum levels of thyroid hormones, thyroid stimulating hormone (TSH), mean arterial pressure (MAP), pulse rate, serum lipid levels and optical coherence tomography findings, were compared between the groups. Independ...
Source: Seminars in Ophthalmology - October 26, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Multimodal imaging features of intraocular foreign bodies.
Conclusion: Understanding the limits of detection for each IOFB type and imaging modality as well as the characteristic features of different IOFBs is of paramount importance to optimizing the management of ocular trauma patients. PMID: 31609153 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - October 16, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Corneal Cross-Linking: An Effective Treatment Option for Pellucid Marginal Degeneration.
Conclusions: The data reported in literature is limited at this time, consisting mostly of retrospective studies with short term follow up. Further research is needed to evaluate refractive effects of combined CXL and excimer laser procedures. PMID: 31449434 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - August 28, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Outer Retinal Healing After Internal Limiting Membrane Peeling in Diabetic Macular Oedema with Vitreomacular Interface Abnormality Using Three Different Dyes.
Conclusion: ICG resulted in a greater percentage of deteriorated EZ/ELM integrity at 6 months after surgery in cases with pre-treatment ELM interruption. Therefore, ICG should be used with caution in cases with ELM disruption, yet, further studies are recommended. PMID: 31423860 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - August 21, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Genetic Variants (rs869109213 and rs2070744) Of the eNOS Gene and BglII in the α2 Subunit of the α2β1 Integrin Gene and Diabetic Retinopathy.
Genetic Variants (rs869109213 and rs2070744) Of the eNOS Gene and BglII in the α2 Subunit of the α2β1 Integrin Gene and Diabetic Retinopathy. Semin Ophthalmol. 2019 Aug 15;:1 Authors: Joob B, Wiwanitkit V PMID: 31416385 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - August 18, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Is Inverse Prism Therapy Comparable to Conventional Prism Therapy for Improving Newcastle Scores in Patients with Basic Intermittent Exotropia?
Conclusion: The two types of prism therapy showed comparable improvements in NCS. PMID: 31402742 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - August 15, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Outcomes of Using Sutureless, Scleral-Fixated Posterior Chamber Intraocular Lenses.
Authors: Kansal V, Onasanya O, Colleaux K, Rawlings N Abstract Background. Implantation of sutureless, scleral-fixated posterior chamber intraocular lenses (SSFIOL) is a promising option in the surgical management of patients unable to undergo standard cataract surgery due to insufficient capsular support. The purpose of this study was to describe the indications, visual outcomes and complications of SSFIOL implantation. Methods. Retrospective, investigational cohort study of 112 consecutive SSFIOL implantations between July 2013 and August 2017. Pre-operative ocular morbidity, operative indications, postoperative ...
Source: Seminars in Ophthalmology - August 10, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Corneal Neurotization: Review of a New Surgical Approach and Its Developments.
Conclusions: The least morbid, simplest, most expedient and successful surgical approaches will ultimately become the most utilized. PMID: 31370735 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - August 4, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Interferon Alfa 2b for Ocular Surface Squamous Neoplasia: Factors Influencing the Treatment Response.
CONCLUSION: Clock hour involvement of ocular surface by OSSN determines the response to IFN. Interferon alfa 2b is an effective immunotherapy agent for tumors ≤6 clock hours of ocular surface in 82% cases and serves as an immunoreducing agent for larger tumors involving>6 clock hours of ocular surface in 26% cases. PMID: 31370766 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - August 4, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

CORRELATIONS between Functional and Structural Tests Measured by Spectral Domain Optical Coherence Tomography in Severe Glaucoma.
Discussion: Mean, superior, inferonasal, superonasal, and superotemporal GC-IPL thicknesses and mean c/d ratio, vertical c/d ratio and cup volume were found to be correlated with BCVA in patients with severe glaucoma. PMID: 31361521 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - August 1, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Descemet's Membrane Endothelial Keratoplasty with Split Corneal Grafts: The Influence of Tamponade Material and Endothelial Storage Time.
Authors: Genc S, Tulu Aygun B, Esen F, Yildirim Y, Agca A Abstract Purpose: The aim of this study was to describe the clinical outcome of Descemet's membrane endothelial keratoplasty (DMEK) performed with split corneal grafts and to evaluate the influence of tamponade material and endothelial storage time on DMEK success. Material and Method: The records of 43 patients who underwent DMEK surgery with a split corneal graft were reviewed. Diagnosis of the patients, preoperative and postoperative best-corrected visual acuity (BCVA), corneal and endothelial storage time, tamponade material, complications, and success r...
Source: Seminars in Ophthalmology - July 31, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Clinical Manifestations of Strabismus in Patients with Primary Congenital Glaucoma.
Authors: Jin SW, Ryu WY Abstract Purpose: To determine the clinical manifestations and risk factors of developing strabismus in primary congenital glaucoma (PCG) patients who underwent glaucoma surgery. Methods: A retrospective case-series study of 54 PCG patients who were followed for at least 3 years after glaucoma surgery. The subjects were divided into 2 groups based on the occurrence of strabismus. Age at glaucoma diagnosis and surgery, visual acuity, intraocular pressure, amblyopia, cup-disc ratio, and orthoptic status were compared between the 2 groups. Results: Twenty of 54 patients (37.0%) developed s...
Source: Seminars in Ophthalmology - July 29, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

An Objective Evaluation of the Upper Eyelid Position after Phacoemulsification Cataract Surgery.
Authors: Marqués-Fernández V, Garcia-Zamora M, Calabuig-Goena M, Diez-Montero C, Schellini SA, Khandekar R, Galindo-Ferreiro A Abstract Purpose: To objectively measure the upper eyelid position following phacoemulsification cataract surgery and to identify the determinants of postoperative transient ptosis. Methods: This is a single arm prospective study of patients who underwent cataract surgery from January to May 2017 at a tertiary Eye Hospital in Spain. Data comprised of: the type of anesthesia, the duration that the speculum remained in place and the total surgical time (duration of the procedure...
Source: Seminars in Ophthalmology - July 19, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Intravitreal Ziv-Aflibercept: A Comprehensive Review.
Conclusion: Further prospective, randomized studies of ziv-aflibercept are needed, particularly in eyes with nAMD. PMID: 31314638 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - July 19, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

The Effect of Eplerenone in Chronic Central Serous Chorioretinopathy Refractory to Photodynamic Therapy.
Conclusions: This study has shown that eplerenone is safe and effective in cases of chronic CSCR, refractory to previous PDT. PMID: 31309849 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - July 18, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

A Review of Machine Learning Techniques for Keratoconus Detection and Refractive Surgery Screening.
Authors: Lin SR, Ladas JG, Bahadur GG, Al-Hashimi S, Pineda R Abstract Various machine learning techniques have been developed for keratoconus detection and refractive surgery screening. These techniques utilize inputs from a range of corneal imaging devices and are built with automated decision trees, support vector machines, and various types of neural networks. In general, these techniques demonstrate very good differentiation of normal and keratoconic eyes, as well as good differentiation of normal and form fruste keratoconus. However, it is difficult to directly compare these studies, as keratoconus represents...
Source: Seminars in Ophthalmology - July 16, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Postoperative Capsular Bag Distension Syndrome - Risk Factors and Treatment.
Conclusion:Nd:YAG posterior capsulotomy, and in some cases anterior capsulotomy, is accepted as a standard and effective CBDS treatment. Surgical approach could be beneficial in cases suspected of Propionibacterium acnes presence or when it is impossible to perform Nd:YAG posterior capsulotomy. PMID: 31298075 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - July 14, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Application of the Balloon Snake in the Volume Measurement of Subretinal Fluid in Central Serous Chorioretinopathy.
Conclusion: The Balloon Snake-based method produced accurate and time-efficient volume measurement of SRF in patients with CSC. PMID: 31288617 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - July 12, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

A Retrospective Study of Transcleral Cyclophotocoagulation Using the Slow Coagulation Technique for the Treatment of Refractory Glaucoma.
Conclusions: Diode laser TSCPC using the slow coagulation technique is a safe and effective technique for lowering IOP in patients with refractory glaucoma in Chinese eyes. PMID: 31284800 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - July 11, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

The Role of Genetic Variants (rs869109213 and rs2070744) Of the eNOS Gene and BglII in the α2 Subunit of the α2β1 Integrin Gene in Diabetic Retinopathy in a Tunisian Population.
In this study, we investigated the association of two polymorphisms (rs869109213 and rs2070744) in the eNOS gene and one polymorphism BglII in the α2β1 integrin gene (ITGA2) with the risk of diabetic retinopathy (DR) in a Tunisian population. Methods: The study investigated of 110 type 2 diabetes mellitus (T2DM) and 127 DR patients. The genotypes of the eNOS 4b/4a (rs869109213) and -786T/C (rs2070744) polymorphisms and of the BglII polymorphism of ITGA2 were studied using the PCR or PCR-RFLP method. Results: The genotype distributions of the two polymorphisms in eNOS 4b4a and eNOS (-786T/C) were significantly di...
Source: Seminars in Ophthalmology - July 2, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Factors Affecting Myopic Regression after Laser in Situ Keratomileusis and Laser-Assisted Subepithelial Keratectomy for High Myopia.
Authors: Liu M, Gao H, Shi W Abstract To evaluate the factors affecting the amount of myopic regression after laser refractive surgery for high myopia, we retrospectively reviewed medical records of 1591 eyes with high myopia treated by laser in situ keratomileusis or laser-assisted subepithelial keratectomy at Shandong Eye Hospital between January 2008 and December 2012. Thirty-five eyes suffering a postoperative myopic shift of manifest spherical equivalent (MSE) of 0.25 diopter (D) or greater were included in this study. The mean refractive error was -9.34 ± 1.89 D before surgery, and the mean r...
Source: Seminars in Ophthalmology - July 2, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Accuracy of Intraocular Lens Power Calculation in Eyes Filled with Silicone Oil.
Authors: Kanclerz P, Grzybowski A Abstract Silicone oil (SO) is used mainly when managing complex retinal detachments, commonly with proliferative vitreoretinopathy, as well as a hemostatic agent in proliferative diabetic retinopathy. Combined lens exchange and pars plana vitrectomy remains preferred by many surgeons; however, sequential surgery might be advantageous to minimize the postoperative anterior chamber inflammatory response, particularly in proliferative diabetic retinopathy or retinal detachment. The aim of the study was to evaluate the optimal method of intraocular lens (IOL) calculation in eyes filled...
Source: Seminars in Ophthalmology - July 2, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

Choroidal Changes at the Leakage Site in Acute Central Serous Chorioretinopathy.
Conclusion: Subfoveal and leak site choroidal profile could predict the eccentricity of leakage in CSCR. PMID: 31257974 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - July 2, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

New Observations regarding the Assessment of Cilioretinal Arteries Coexistence with Optic Disc Pit.
Conclusion: Based on the high percentage of CRAs coexistence with ODP and the excessive frequency of their emergence from ODP (83.3%), it is supported that ODP as a developmental disorder could go along with further anatomic peculiarities, that also include the presence of multiple CRAs. PMID: 31244378 [PubMed - as supplied by publisher] (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - June 29, 2019 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research