Cancer on the baby monitor: Parents who spotted strange mark on their son's eye are told they were result of rare TUMOR
Benny was only six months old when doctors diagnosed him with retinoblastoma - a type of cancer in the eye. The boy from Utah was treated using chemotherapy. (Source: the Mail online | Health)
Source: the Mail online | Health - October 17, 2023 Category: Consumer Health News Source Type: news
Consumer Health: What do you know about these 3 rare childhood cancers?
Childhood cancer rates have been rising slightly for the past few decades, and about 10,470 children in the U.S. under the age of 15 will be diagnosed with cancer in 2022, according to the American Cancer Society. September is Childhood Cancer Awareness Month, which makes this a good time to learn about three rare types of cancers in children: retinoblastoma, rhabdomyosarcoma and Wilms' tumor. Retinoblastoma Retinoblastoma is a rare form of eye cancer that begins in the… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - September 26, 2022 Category: Databases & Libraries Source Type: news
These pesticides may increase cancer risk in children
Key takeaways:Higher cancer risk. Prenatal exposure to acephate and other pesticides can increase the risk of retinoblastoma, or eye cancer, in children.Environmental causes. Children with retinoblastoma are more likely to be born in neighborhoods near applications of specific chemicals.Past research has shown that pesticide exposure increases the risk of cancer. Now, UCLA-led research has exposed which specific pesticides increase the risk of retinoblastoma — a rare eye tumor — in children.Thestudy, published in the August International Journal of Hygiene and Environmental Health, found that children prenatally expo...
Source: UCLA Newsroom: Health Sciences - September 13, 2022 Category: Universities & Medical Training Source Type: news
iPhone Flash Helps Nurse Identify Her Infant Son's Retinoblastoma iPhone Flash Helps Nurse Identify Her Infant Son's Retinoblastoma
An inadvertent flash exposed an unusual glow in her son ' s right eye. Now, a smartphone app can help parents identify possible eye disorders early.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 27, 2021 Category: Consumer Health News Tags: Nursing News Source Type: news
Oncotarget: Piperlongumine promotes death of retinoblastoma cancer cells
(Impact Journals LLC) These Oncotarget findings suggest that PL reduces tumor growth and induces cell death by regulating the cell cycle (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 31, 2021 Category: Cancer & Oncology Source Type: news
By age 10, retinoblastoma patients' learning and life skills rebound
(St. Jude Children's Research Hospital) St. Jude Children's Research Hospital researchers studied how retinoblastoma survivors fared years later at home and at school. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 6, 2021 Category: Cancer & Oncology Source Type: news
What Is the Survival Rate of Retinoblastoma?
Title: What Is the Survival Rate of Retinoblastoma?Category: Diseases and ConditionsCreated: 10/22/2020 12:00:00 AMLast Editorial Review: 10/22/2020 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - October 22, 2020 Category: Cancer & Oncology Source Type: news
Does Retinoblastoma Cause Blindness?
Title: Does Retinoblastoma Cause Blindness?Category: Diseases and ConditionsCreated: 10/21/2020 12:00:00 AMLast Editorial Review: 10/21/2020 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - October 21, 2020 Category: Cancer & Oncology Source Type: news
Therapy using immune system cells preserves vision in mice implanted with rare eye cancer
(UNC Lineberger Comprehensive Cancer Center) A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with retinoblastoma tissue. The cancer, which is most commonly diagnosed in infants and young children, is treatable in early stages but can still lead to the loss of vision in about 5% of cases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 12, 2020 Category: Cancer & Oncology Source Type: news
Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division
Cell size is fundamental to cell physiology. For example, cell size determines the spatial scale of organelles and intracellular transport and thereby affects biosynthesis. Although some genes that affect mammalian cell size have been identified, the molecular mechanisms through which cell growth drives cell division have remained elusive. We show that cell growth during the G1 phase of the cell division cycle dilutes the cell cycle inhibitor Retinoblastoma protein (Rb) to trigger division in human cells. RB overexpression increased cell size and G1 duration, whereas RB deletion decreased cell size and removed the inverse ...
Source: ScienceNOW - July 22, 2020 Category: Science Authors: Zatulovskiy, E., Zhang, S., Berenson, D. F., Topacio, B. R., Skotheim, J. M. Tags: Cell Biology, Engineering reports Source Type: news
3 Brothers Have the Same Rare Cancer
The Rush brothers, ages 5 years, 4 years, and 7 months, share something that most brothers don’t: bilateral retinoblastoma, a rare eye cancer. See how their mother, who was also born with the disease, handles treatments, daily life, and facing the unknown. (Source: WebMD Health)
Source: WebMD Health - February 11, 2020 Category: Consumer Health News Source Type: news
Three Georgia brothers under six are all battling the same rare eye cancer
Brothers Tristan Rush, five; Caison Rush, three; and Carter Rush. six months, from Marietta, Georgia have all been diagnosed with retinoblastoma, a rare form of eye cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - February 4, 2020 Category: Consumer Health News Source Type: news
p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition
The p27 protein is a canonical negative regulator of cell proliferation and acts primarily by inhibiting cyclin-dependent kinases (CDKs). Under some circumstances, p27 is associated with active CDK4, but no mechanism for activation has been described. We found that p27, when phosphorylated by tyrosine kinases, allosterically activated CDK4 in complex with cyclin D1 (CDK4-CycD1). Structural and biochemical data revealed that binding of phosphorylated p27 (phosp27) to CDK4 altered the kinase adenosine triphosphate site to promote phosphorylation of the retinoblastoma tumor suppressor protein (Rb) and other substrates. Surpri...
Source: ScienceNOW - December 11, 2019 Category: Science Authors: Guiley, K. Z., Stevenson, J. W., Lou, K., Barkovich, K. J., Kumarasamy, V., Wijeratne, T. U., Bunch, K. L., Tripathi, S., Knudsen, E. S., Witkiewicz, A. K., Shokat, K. M., Rubin, S. M. Tags: Biochemistry, Medicine, Diseases, Online Only r-articles Source Type: news
Markedly Elevated Sarcoma Risk in Long-Term Survivors of Hereditary Retinoblastoma Markedly Elevated Sarcoma Risk in Long-Term Survivors of Hereditary Retinoblastoma
The risk of bone and soft-tissue sarcoma is markedly elevated in long-term survivors of hereditary retinoblastoma treated with radiation, researchers report.Reuters Health Information (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - November 26, 2019 Category: Orthopaedics Tags: Hematology-Oncology News Source Type: news