Outlook For Minority, Uninsured Pediatric Retinoblastoma Patients Worsened By Delays In Diagnosis
When the eye cancer retinoblastoma is diagnosed in racial and ethnic minority children whose families don't have private health insurance, it often takes a more invasive, potentially life-threatening course than in other children, probably because of delays in diagnosis, Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) researchers report at the 26th annual meeting of the American Society of Pediatric Hematology Oncology being held in Miami, April 24-27... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 26, 2013 Category: Consumer Health News Tags: Eye Health / Blindness Source Type: news
UCLA researchers find potential link between auto pollution, some childhood cancers
Scientists from UCLA's Fielding School of Public Health led by Julia Heck, an assistant researcher in the school's epidemiology department and a member of UCLA's Jonsson Comprehensive Cancer Center, have found a possible link between exposure to traffic-related air pollution and several childhood cancers.
The results of their study — the first to examine air pollution from traffic and a number of rarer childhood cancers — were presented on April 9 in an abstract at the annual meeting of the American Association for Cancer Research in Washington, D.C.
For the study, the UCLA researchers utilized data on 3,...
Source: UCLA Newsroom: Health Sciences - April 9, 2013 Category: Universities & Medical Training Source Type: news
Some Aggressive Retinoblastomas Lack RB1 Mutations Some Aggressive Retinoblastomas Lack RB1 Mutations
Most retinoblastomas are driven by loss of the RB1 genes; now researchers find amplification of the MYCN gene causes some very-early-onset retinoblastomas. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 19, 2013 Category: Consumer Health News Tags: Ophthalmology News Source Type: news
Cancer researchers discover new type of retinoblastoma in babies
(University Health Network) A team of Canadian and international cancer researchers led by Dr. Brenda Gallie at the Princess Margaret Cancer Centre, University Health Network, has discovered a new type of retinoblastoma, a rapidly developing eye cancer that affects very young babies -- a finding that can immediately change clinical practice and optimize care for these children. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 12, 2013 Category: Global & Universal Source Type: news
Regulating Differentiation Of Myeloid Cells In Cancer By Silencing Retinoblastoma Gene
Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer. This mechanism includes silencing the tumor suppressor gene retinoblastoma 1 or Rb1. Their data explains a new regulatory mechanism by which myeloid-derived suppressor cells are expanded in cancer. Their study appeared in a recent issue of Nature Immunology... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 21, 2013 Category: Consumer Health News Tags: Lymphoma / Leukemia / Myeloma Source Type: news
Moffitt researchers say silencing of retinoblastoma gene regulates differentiation of myeloid cells
(H. Lee Moffitt Cancer Center & Research Institute) Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer. This mechanism includes silencing the tumor suppressor gene retinoblastoma 1 or Rb1. Their data explains a new regulatory mechanism by which myeloid-derived suppressor cells are expanded in cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 19, 2013 Category: Global & Universal Source Type: news
Array Comparative Genomic Hybridization in Osteosarcoma
Osteosarcoma, the most frequent primary bone tumor, is a malignant mesenchymal sarcoma with a peak incidence in young children and adolescents. Left untreated, it progresses relentlessly to local and systemic disease, ultimately leading to death within months. Genomically, osteosarcomas are aneuploid with chaotic karyotypes, lacking the pathognomonic genetic rearrangements characteristic of most sarcomas. The familial genetics of osteosarcoma helped in elucidating some of the etiological molecular disruptions, such as the tumor suppressor genes RB1 in retinoblastoma and TP53 in Li–Fraumeni, and RECQL4 involved in DNA...
Source: Springer protocols feed by Genetics/Genomics - February 15, 2013 Category: Genetics & Stem Cells Source Type: news
