Follicular carcinoma of the thyroid with a single metastatic lesion in the lumbar spine: A case report
CONCLUSION: Follicular thyroid carcinoma is associated with early hematogenous metastasis, and the bone is a typical site of metastasis. Single bone metastasis is not a contraindication to medical procedures, and providing the appropriate therapy can result in better outcomes and quality of life for these patients.PMID:36159419 | PMC:PMC9477679 | DOI:10.12998/wjcc.v10.i26.9493 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - September 26, 2022 Category: Cancer & Oncology Authors: Yao-Kun Chen Yu-Chun Chen Wei-Xun Lin Jie-Hua Zheng Yi-Yuan Liu Juan Zou Jie-Hui Cai Ze-Qi Ji Ling-Zhi Chen Zhi-Yang Li Ye-Xi Chen Source Type: research
Follicular carcinoma of the thyroid with a single metastatic lesion in the lumbar spine: A case report
CONCLUSION: Follicular thyroid carcinoma is associated with early hematogenous metastasis, and the bone is a typical site of metastasis. Single bone metastasis is not a contraindication to medical procedures, and providing the appropriate therapy can result in better outcomes and quality of life for these patients.PMID:36159419 | PMC:PMC9477679 | DOI:10.12998/wjcc.v10.i26.9493 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - September 26, 2022 Category: Cancer & Oncology Authors: Yao-Kun Chen Yu-Chun Chen Wei-Xun Lin Jie-Hua Zheng Yi-Yuan Liu Juan Zou Jie-Hui Cai Ze-Qi Ji Ling-Zhi Chen Zhi-Yang Li Ye-Xi Chen Source Type: research
Follicular carcinoma of the thyroid with a single metastatic lesion in the lumbar spine: A case report
CONCLUSION: Follicular thyroid carcinoma is associated with early hematogenous metastasis, and the bone is a typical site of metastasis. Single bone metastasis is not a contraindication to medical procedures, and providing the appropriate therapy can result in better outcomes and quality of life for these patients.PMID:36159419 | PMC:PMC9477679 | DOI:10.12998/wjcc.v10.i26.9493 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - September 26, 2022 Category: Cancer & Oncology Authors: Yao-Kun Chen Yu-Chun Chen Wei-Xun Lin Jie-Hua Zheng Yi-Yuan Liu Juan Zou Jie-Hui Cai Ze-Qi Ji Ling-Zhi Chen Zhi-Yang Li Ye-Xi Chen Source Type: research
Cancers, Vol. 14, Pages 4687: BRAFV600E Expression in Thyrocytes Causes Recruitment of Immunosuppressive STABILIN-1 Macrophages
ichel Mourad
Patrick Henriet
Donatienne Tyteca
Etienne Marbaix
Christophe E. Pierreux
Papillary thyroid carcinoma (PTC) is the most frequent histological subtype of thyroid cancers (TC), and BRAFV600E genetic alteration is found in 60% of this endocrine cancer. This oncogene is associated with poor prognosis, resistance to radioiodine therapy, and tumor progression. Histological follow-up by anatomo-pathologists revealed that two-thirds of surgically-removed thyroids do not present malignant lesions. Thus, continued fundamental research into the molecular mechanisms of TC downstream of BRAFV600E remains central...
Source: Cancers - September 26, 2022 Category: Cancer & Oncology Authors: Catherine Spourquet Oph élie Delcorte Pascale Lemoine Nicolas Dauguet Axelle Loriot Younes Achouri Maija Hollm én Sirpa Jalkanen Fran çois Huaux Sophie Lucas Pierre Van Meerkeeck Jeffrey A. Knauf James A. Fagin Chantal Dessy Michel Mourad Patrick Henri Tags: Article Source Type: research
Radioiodine therapy in the different stages of differentiated thyroid cancer
This article will review the key factors to consider when planning radioactive iodine therapy in differentiated thyroid cancer patients after surgery and during follow up.PMID:36151009 | DOI:10.1016/j.beem.2022.101703 (Source: Cancer Control)
Source: Cancer Control - September 23, 2022 Category: Cancer & Oncology Authors: Laura Valerio Fabio Maino Maria Grazia Castagna Furio Pacini Source Type: research
Oncological theranostics in nuclear medicine
Radiologie (Heidelb). 2022 Sep 16. doi: 10.1007/s00117-022-01072-w. Online ahead of print.ABSTRACTThe theranostic principle describes the diagnostic and therapeutic use of radioactive nuclides linked to biochemically active ligands. The oldest and most prominent field of application of theranostics in oncology is differentiated thyroid cancer treated by radioiodine therapy, which allows imaging of the iodine uptake and thus tumor manifestations by gamma (γ) radiation of radioiodine. Other areas of application include neuroendocrine tumors, castration-resistant prostate cancer and, in the context of individual therapeutic ...
Source: Nuklearmedizin - September 16, 2022 Category: Radiology Authors: Christina Laschinsky Ken Herrmann Wolfgang Fendler Michael Nader Harald Lahner Boris Hadaschik Patrick Sandach Source Type: research
Oncological theranostics in nuclear medicine
Radiologie (Heidelb). 2022 Sep 16. doi: 10.1007/s00117-022-01072-w. Online ahead of print.ABSTRACTThe theranostic principle describes the diagnostic and therapeutic use of radioactive nuclides linked to biochemically active ligands. The oldest and most prominent field of application of theranostics in oncology is differentiated thyroid cancer treated by radioiodine therapy, which allows imaging of the iodine uptake and thus tumor manifestations by gamma (γ) radiation of radioiodine. Other areas of application include neuroendocrine tumors, castration-resistant prostate cancer and, in the context of individual therapeutic ...
Source: Nuklearmedizin - September 16, 2022 Category: Radiology Authors: Christina Laschinsky Ken Herrmann Wolfgang Fendler Michael Nader Harald Lahner Boris Hadaschik Patrick Sandach Source Type: research
Oncological theranostics in nuclear medicine
Radiologie (Heidelb). 2022 Sep 16. doi: 10.1007/s00117-022-01072-w. Online ahead of print.ABSTRACTThe theranostic principle describes the diagnostic and therapeutic use of radioactive nuclides linked to biochemically active ligands. The oldest and most prominent field of application of theranostics in oncology is differentiated thyroid cancer treated by radioiodine therapy, which allows imaging of the iodine uptake and thus tumor manifestations by gamma (γ) radiation of radioiodine. Other areas of application include neuroendocrine tumors, castration-resistant prostate cancer and, in the context of individual therapeutic ...
Source: Nuklearmedizin - September 16, 2022 Category: Radiology Authors: Christina Laschinsky Ken Herrmann Wolfgang Fendler Michael Nader Harald Lahner Boris Hadaschik Patrick Sandach Source Type: research
Oncological theranostics in nuclear medicine
Radiologie (Heidelb). 2022 Sep 16. doi: 10.1007/s00117-022-01072-w. Online ahead of print.ABSTRACTThe theranostic principle describes the diagnostic and therapeutic use of radioactive nuclides linked to biochemically active ligands. The oldest and most prominent field of application of theranostics in oncology is differentiated thyroid cancer treated by radioiodine therapy, which allows imaging of the iodine uptake and thus tumor manifestations by gamma (γ) radiation of radioiodine. Other areas of application include neuroendocrine tumors, castration-resistant prostate cancer and, in the context of individual therapeutic ...
Source: Nuklearmedizin - September 16, 2022 Category: Radiology Authors: Christina Laschinsky Ken Herrmann Wolfgang Fendler Michael Nader Harald Lahner Boris Hadaschik Patrick Sandach Source Type: research
Oncological theranostics in nuclear medicine
Radiologie (Heidelb). 2022 Sep 16. doi: 10.1007/s00117-022-01072-w. Online ahead of print.ABSTRACTThe theranostic principle describes the diagnostic and therapeutic use of radioactive nuclides linked to biochemically active ligands. The oldest and most prominent field of application of theranostics in oncology is differentiated thyroid cancer treated by radioiodine therapy, which allows imaging of the iodine uptake and thus tumor manifestations by gamma (γ) radiation of radioiodine. Other areas of application include neuroendocrine tumors, castration-resistant prostate cancer and, in the context of individual therapeutic ...
Source: Nuklearmedizin - September 16, 2022 Category: Radiology Authors: Christina Laschinsky Ken Herrmann Wolfgang Fendler Michael Nader Harald Lahner Boris Hadaschik Patrick Sandach Source Type: research
Oncological theranostics in nuclear medicine
Radiologie (Heidelb). 2022 Sep 16. doi: 10.1007/s00117-022-01072-w. Online ahead of print.ABSTRACTThe theranostic principle describes the diagnostic and therapeutic use of radioactive nuclides linked to biochemically active ligands. The oldest and most prominent field of application of theranostics in oncology is differentiated thyroid cancer treated by radioiodine therapy, which allows imaging of the iodine uptake and thus tumor manifestations by gamma (γ) radiation of radioiodine. Other areas of application include neuroendocrine tumors, castration-resistant prostate cancer and, in the context of individual therapeutic ...
Source: Nuklearmedizin - September 16, 2022 Category: Radiology Authors: Christina Laschinsky Ken Herrmann Wolfgang Fendler Michael Nader Harald Lahner Boris Hadaschik Patrick Sandach Source Type: research
Accessory Thyroid Tissue Detected Using 131I SPECT/CT Imaging
Thyroid ectopia has been described as a rare congenital anomaly, characterized by the presence of a thyroid gland in locations other than the orthotopic pretracheal location. The prevalence of accessory thyroid tissue in patients undergoing postablative radioiodine therapy in a 12-month period at a tertiary hospital nuclear medicine department was assessed. Fifty-seven patients were treated between September 2020 and September 2021. Retrospective analysis identified the presence and location of all accessory thyroid tissue separate from the orthotopic pretracheal thyroid gland. Accessory thyroid tissue was present in 21.1%...
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Papillary Thyroid Carcinoma Arising from Thyroglossal Cyst—an Institutional Experience over a Decade
AbstractPapillary carcinoma constitutes 80% of thyroglossal duct cyst carcinoma (TGCC). The mainstay of treatment for TGCC is Sistrunk procedure. Due to lack of clear-cut guidelines in managing TGCC, the role of total thyroidectomy, neck dissection and adjuvant radioiodine therapy is still debatable. This was a retrospective study which included cases of TGCC treated in our institution over a period of 11 years. The aim of study was to assess the need for total thyroidectomy in management of TGCC. Patients were divided into two groups based on the surgical treatment they underwent and the tre atment outcomes were compar...
Source: Indian Journal of Surgical Oncology - September 3, 2022 Category: Cancer & Oncology Source Type: research
Alterations in Oral Microbiota of Differentiated Thyroid Carcinoma Patients With Xerostomia After Radioiodine Therapy
ConclusionOur study suggests for the first time that DTC patients with xerostomia after RAI display microbiota profiles and associated functional changes that may promote a pro-inflammatory environment. Dysbiosis of the oral microbiota may contribute to exacerbating the severity of xerostomia. Our results provide a research direction of the interaction mechanism between oral microbiota alteration and the progress of xerostomia. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - August 26, 2022 Category: Endocrinology Source Type: research
The high degree of similarity in histopathological and clinical characteristics between radiogenic and sporadic papillary thyroid microcarcinomas in young patients
This study aims to determine whether there are differences in the behavior of MPTC of two etiological forms (radiogenic and sporadic), including invasive properties, clinical data, and recurrence in patients aged up to 30 years. For this purpose, 136 radiogenic (from patients aged up to 18 years at the time of the Chornobyl accident) and 83 sporadic (from patients born after the Chornobyl accident) MPTCs were selected and compared using univariate and multivariate statistical methods in a whole group and in age and tumor size subgroups. No evidence of more aggressive clinical and histopathological behavior of radiogenic MP...
Source: Frontiers in Endocrinology - August 19, 2022 Category: Endocrinology Source Type: research
