Ewing ’s Sarcoma of Scapula: a Rare Case Report
AbstractNeoplasms arising from scapula are rare. We herein, present a rare case of Ewing ’s sarcoma of scapula in a 9-year-old male child. Extensive literature search reveals that less than 20 similar cases have been reported so far. The index case had been treated with multimodal therapies—chemotherapy, surgery, and radiotherapy. This case is reported to highlight the rarity of the case and discuss the review of literature comprehensively. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - November 19, 2018 Category: Cancer & Oncology Source Type: research

Analysis of Factors Affecting the Longevity of Voice Prosthesis Following Total Laryngectomy with a Review of Literature
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - November 19, 2018 Category: Cancer & Oncology Source Type: research

Perioperative Mortality in Cancer Esophagus —a Case Control Study at a High-Volume Regional Cancer Center in South India
AbstractSurgery for esophageal cancers carries high rates of morbidity and mortality despite improvements in perioperative care especially with increasingly safe anesthesia and postoperative ICU care. A case control study was conducted on 713 patients operated for esophageal cancer over a period of 8  years (2009–2016). Multiple preoperative, intraoperative, and postoperative clinical and laboratory parameters were compared between patients who succumbed to the surgery, i.e., 30-day mortality, and those who did not. Of the preoperative parameters, age >  58.5 years (p = 0.01),...
Source: Indian Journal of Surgical Oncology - November 14, 2018 Category: Cancer & Oncology Source Type: research

Central Hepatectomy (Mesohepatectomy) by Double Liver Hanging Maneuver (DLHM) in a Child with Hepatoblastoma
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - November 13, 2018 Category: Cancer & Oncology Source Type: research

Carcinosarcoma of Submandibular Salivary Gland with a Rare Sarcomatous Variant
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - October 31, 2018 Category: Cancer & Oncology Source Type: research

Prognostic Significance of Anatomic Origin and Evaluation of Survival Statistics of Astrocytoma Patients —a Tertiary Experience
AbstractAstrocytoma constitutes the most noted malignancies of the central nervous system with worse clinical outcomes in grade IV astrocytoma or glioblastoma multiforme. Owing to poor clinical outcomes with existing therapeutic regime, there is a need to revisit the initial course of treatment. Statistical information of clinicopathological parameters could be used to understand the spread of disease and, in turn, to formulate updated treatment management. In the present study, we have seen anatomic distribution of astrocytoma subtypes in a group of 479 patients and correlated it with survival outcomes. Anatomic location ...
Source: Indian Journal of Surgical Oncology - October 30, 2018 Category: Cancer & Oncology Source Type: research

Outcome of 150 Consecutive Blumgart ’s Pancreaticojejunostomy After Pancreaticoduodenectomy
AbstractPostoperative pancreatic fistula (POPF) is the most feared complication after pancreaticoduodenectomy (PD) that leads to intra-abdominal abscess, sepsis, or bleeding and remains the single most important source of morbidity and mortality after PD. To minimize this dreaded complication, various surgical techniques and modifications of pancreaticoenteric reconstruction have been proposed. However, still POPF does occur even in experienced hands. We herein describe the outcome of 150 post PD patients who underwent duct-to-mucosa (DM) pancreaticojejunostomy (PJ) using a special technique, Blumgart ’s “throu...
Source: Indian Journal of Surgical Oncology - October 27, 2018 Category: Cancer & Oncology Source Type: research

Prognostic Value of Metastatic Lymph Node Ratio in Pancreatic Cancer
AbstractLymph node involvement in pancreatic adenocancer is one of the strongest predictors of prognosis. However, the extent of lymph node dissection is still a matter of debate and number of dissected nodes varies widely among patients. In order to homogenize this diverse group of patients and more accurately predict their prognosis, we aimed to analyze the effect of metastatic lymph node ratio as an independent prognostic factor. We retrospectively analyzed medical recordings of 326 patients with pancreatic cancer who were treated in a tertiary medical oncology center over a 10-year period. Both in univariate and multiv...
Source: Indian Journal of Surgical Oncology - October 26, 2018 Category: Cancer & Oncology Source Type: research

Pinch-Off Syndrome and Fracture Embolization: a Preventable Complication of TIVADS
AbstractTotally implantable venous access device has become indispensable in oncology. One of the well-known complications of the subclavian approach is the pinch-off syndrome. We hereby describe how a case of pinch-off syndrome with catheter fracture and embolization into the heart was managed by prompt endovascular intervention. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - October 18, 2018 Category: Cancer & Oncology Source Type: research

Rate of Breast-Conserving Surgery vs Mastectomy in Breast Cancer: a Tertiary Care Centre Experience from South India
AbstractWorldwide, breast conservation has become increasingly accepted as the surgical management of breast cancer in clinical practice. Cancer care in India is also evolving tremendously with many cancer treatment centres following evidence-based practice hence the rates of breast conservation are expected to increase. Here, we are reporting the rate of breast-conserving surgery (BCS) at our centre. A retrospective study of 401 patients who underwent breast cancer surgery at a tertiary care centre in South India from January 2015 to August 2017 were analysed to study the rate of BCS. All early breast cancers (EBC) were o...
Source: Indian Journal of Surgical Oncology - October 16, 2018 Category: Cancer & Oncology Source Type: research

Basaloid Squamous Cell Carcinoma of Tonsil: an Unusual and Aggressive Variant
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - October 15, 2018 Category: Cancer & Oncology Source Type: research

Decadal Experience of Renal Cell Carcinoma from a Tertiary Care Teaching Institute in North India
AbstractTo study the current trends of renal cell carcinoma (RCC) in terms of demographic characteristics, clinical presentation, staging, mode of management, histopathology, and survival characteristics from a high volume tertiary care teaching institute in North India. We retrospectively reviewed the records of all patients of RCC between January 2006 and December 2015 and variables like age, gender, symptoms, tumor size/location/number, stage, type of surgery, histopathology, and survival characteristics were studied. One hundred forty-four patients were included in the study. Most common age group of presentation was 5...
Source: Indian Journal of Surgical Oncology - September 22, 2018 Category: Cancer & Oncology Source Type: research

Role of Ultrasonography in the Surveillance of Disease-Free Patients with Colorectal Cancer: a Retrospective Audit
AbstractClose surveillance of colorectal cancer (CRC) patients is helpful as early detection of resectable metastasis has a survival benefit. Ultrasonography (USG) is a frequently used modality to detect liver recurrence, although international guidelines do not include it. To evaluate the potential added role of USG in early detection of CRC recurrence. We performed a retrospective analysis of 230 patients of colorectal cancer treated at our institute in 2013 –2014 who underwent abdominal USG for surveillance. 77/230 (33%) developed recurrence, with liver being the second most common site (22/230). 5/230 (2%) patien...
Source: Indian Journal of Surgical Oncology - September 4, 2018 Category: Cancer & Oncology Source Type: research

Prevalence and Impact of Human Papillomavirus on Head and Neck Cancers: Review of Indian Studies
This article reviews the prevalence of HPV-related HNCs across various studies in India where the population is predominantly tobacco users, and studies its outcomes with respect to HPV. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - September 3, 2018 Category: Cancer & Oncology Source Type: research

Acute Trauma Precipitating the Onset of Chest Wall Myxofibrosarcoma
AbstractA previously healthy, 47-year-old male presented to his primary care physician with the complaint of a nontender, palpable breast mass discovered coincidentally 1  month after being scratched in the same location by his pet cat. Family history revealed his father was diagnosed with a soft tissue sarcoma of the thigh, 6 months following a traumatic injury in the same location. Cat scratch disease was considered; however,Bartonella Henselae antibody testing was negative. Imaging studies revealed a subpectoral mass without rib involvement. Subsequent core biopsy revealed malignant fibrous histiocytoma, myxoi...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Lymphatic Microsurgical Preventing Healing Approach (LYMPHA) for Prevention of Breast Cancer-Related Lymphedema —a Preliminary Report
AbstractLymphatic microsurgical preventing healing approach (LYMPHA) for prevention of breast cancer-related lymphedema (BCRL) —a preliminary report BCRL—is a chronic debilitating condition which impairs quality of life of breast cancer survivors. The aim is to study the feasibility of preventing lymphedema by performing “Lymphatic Microsurgical Preventive Healing Approach (LYMPHA).” Patients undergoing breast cance r surgery with complete nodal dissection were taken up for the study. After the standard axillary nodal dissection, lymphatics were identified by the help of blue dye and were anastomose...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Identification of Sentinel Lymph Nodes Using Contrast-Enhanced Ultrasound in Breast Cancer
AbstractSentinel lymph node (SLN) biopsy has become the standard of care in axillary staging of breast cancer patients who are clinically node negative as it reduces the morbidity of axillary nodal dissection. SLN biopsy using blue dye and radioisotopes have high identification rates but its limitations include anaphylaxis, disposal of radioactive waste, and potential second surgery in up to 35% of patients who show nodal metastases on SLN biopsy. Contrast-enhanced ultrasound (CEUS) has the potential for SLNs to be identified without the aforementioned risks. CEUS involves the administration of intravenous contrast agents ...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Carcinosarcoma of Breast Mimicking Breast Abscess
AbstractCarcinosarcoma, a tumor having both carcinomatous and sarcomatous elements, occurring in the breast, is a rare condition. The tumor consists of both epithelial and mesenchymal cell lines and tends to behave aggressively. It has clinical features like that of invasive breast carcinoma but sometimes there can be diagnostic confusion as it can mimic or present as breast abscess. Treatment is multimodal. Surgery plays the vital role. Post-op radiation and chemo are indicated. Hormone therapy is usually inapplicable as most of the time, it is hormone receptor negative. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Clinico-pathological Features of PIK3CA Mutation in HER2-Positive Breast Cancer of Indian Population
In conclusion, we identified 24.2% somatic mutation of PIK3CA in HER2-positive breast cancer patients. PIK3CA mutation is significantly associated with ER-positive tumors. The frequency and distribution pattern reported in this study is similar to the global report. Overall survival of PIK3CA mutation is slightly lower but in patients who received herceptin with PIK3CA mutation showed better clinical outcome. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Ovarian Transposition in a Young Girl with Primitive Neuroectodermal Tumor of Bladder
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Dermatofibrosarcoma Protuberans of the Breast —a Rare Entity
AbstractDermatofibrosarcoma protuberans (DFSP) represents about 1% of soft-tissue sarcomas with an estimated incidence of 0.8 to 5.0 cases per million per year. This lesion may occur anywhere in the body but more than 50% occur on the trunk, 20% on the head and neck and 30% on the extremities. DFSP of the breast is an extremely uncommon site of presentation. Data regarding DFSP of the breast is limited and mostly in the form of case reports. Clinical presentation is not uniform and may mimic benign skin lesions [1]. However, it typically presents as a nodular cutaneous mass in early or mid-adult life. We herein report a ca...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Prospective Evaluation of Surgical Outcome After Transoral CO 2 Laser Resection of Potentially Malignant and Early Oral Malignancy
AbstractA prospective observational study was done at the Regional Cancer Centre, Thiruvananthapuram, a tertiary referral center for cancer care in India with an aim to assess the surgical outcomes of CO2 laser resection of oral lesions in terms of operative time, blood loss, hospital stay, postoperative pain, time to re-epithelization, pathological margins achieved and the postoperative scar. The excision was performed in 30 patients with a diagnosis of either potentially malignant lesions (leucoplakia, erythroplakia) or early cancers, i.e., carcinoma in situ or T1/T2 squamous cell carcinoma of the anterior oral cavity (t...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Extensive Re-ossification and Reformation of the Proximal Femur After External Beam Radiotherapy in Metastatic Carcinoma Breast
In this report, we describe a case of breast carcinoma with a large metastatic lytic lesion in the proximal femur, which was treated by in situ fixation followed by hormonal therapy and external beam radiotherapy. In the post-operative period, rapid and dramatic ossification and reformation of the proximal femur was observed. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Encapsulated Follicular Variant of Papillary Thyroid Carcinoma Arising in a Follicular Adenoma: a Diagnostic Dilemma
AbstractPapillary thyroid carcinoma (PTC) arising within follicular adenoma is a rare histological subset of papillary carcinoma. A 24-year-old female (euthyroid and asymptomatic) presented with a solitary mass in the right lobe of thyroid for 2  years. Fine-needle aspiration cytology (FNAC) suggested features of hyperplasia of thyroid. Hemithyroidectomy was performed. Histopathological examination revealed two distinct areas and was reported as encapsulated variant of papillary carcinoma along with follicular adenoma. Papillary carcinoma was confirmed by positive immunohistochemistry for HBME-1. CT head and neck regi...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Rare Case Report of Neuroendocrine Tumor in Axilla-Metastasis from Unknown Primary or De Novo?
AbstractNeuroendocrine tumors (NET) are the neoplasm arising from neuroendocrine cells which are present throughout the body. It can be benign, being more common or malignant. Gut is the most common site, but they can be seen in any part of the body. We had a case of grade III NET in axilla presented with a fungating lesion with unknown primary. Clinical behavior of such tumor is predicted by tumor grade or differentiation. We treated this patient by surgery and adjuvant chemotherapy. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Unusual Breast Neoplasm with Diagnostic and Management Challenges
AbstractWith the growing awareness and availability of proper screening methods, detection of breast lump is increasing globally and is now a very sensitive issue for females. The treatment of these lumps ranges from lumpectomy to wide local excision to mastectomy; hence, a proper diagnosis is very important to prevent under- or overtreatment in patients. Breast lesions are the heterogeneous diseases encompassing several distinct entities with remarkably different characteristics. While the more common forms of breast cancers are well recognized and understood better, there are many important unusual lesions and malignanci...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Oncologic and Cosmetic Outcomes of Oncoplastic Breast Surgery in Locally Advanced Breast Cancer After Neoadjuvant Chemotherapy, Experience from a Developing Country
AbstractOncoplastic surgery (OPS) has emerged as a new approach for extending breast conserving surgery (BCS) possibilities, reducing both mastectomy and re-excision rates, while avoiding breast deformities. OPS is based upon the integration of plastic surgery techniques for immediate reshaping after wide excision for breast cancer. This is a prospective feasibility cohort study of oncoplastic breast surgery after neoadjuvant chemotherapy that was carried at the National Cancer Institute, Cairo University and included 70 patients. The primary outcome was the local recurrence rate. Secondary outcomes included survival and m...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Patterns of Care of Breast Cancer Patients in a Rural Cancer Center in Western India
AbstractBreast cancer is an emerging public health problem in low- and middle-income countries. The main objective is to describe the clinical characteristics and patterns of care of breast cancer patients diagnosed and treated in a rural cancer hospital in Barshi, Western India. The results from a cross-sectional study of 99 consecutive breast cancer patients diagnosed and treated between February 2012 and November 2014 in Nargis Dutt Memorial Cancer Hospital is reported. The case records of the patients were scrutinized and reviewed to abstract data on their clinical characteristics, diagnostic, and treatment details. Th...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Nipple Areola Complex Involvement in Invasive Carcinoma Breast
AbstractA variety of factors including tumor biology and distance of the tumor from the nipple have been associated with nipple areola complex involvement in patients with breast cancer. Preoperative understanding regarding these factors can help in modifying the surgical options including preservation of nipple areola complex (NAC) and breast conservation. Nipple sparing surgery (breast conservation surgery/skin sparing mastectomy with immediate reconstruction) for breast cancer has gained widespread interest with the aim of achieving oncologically safe and cosmetically acceptable outcome. To study the proportion of cases...
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

Giant Calcified Retroperitoneal Teratoma
AbstractRetroperitoneal teratoma involving adrenal gland is a rare entity in adults comprising only 4% of all primary teratomas. These tumors are mainly seen in infants and children. Diagnosis is made by X-ray and CT abdomen showing the presence of large tumor with cystic and calcified walls. Here, we present an interesting image of a 16-year-old girl who presented with large (12  × 10 cm) calcified cyst occupying left side of abdomen which was treated successfully by surgical excision. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

From the Desk of the Editor
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - September 1, 2018 Category: Cancer & Oncology Source Type: research

A Rare Case of Synchronous Cervical and Breast Carcinoma
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - August 29, 2018 Category: Cancer & Oncology Source Type: research

Ovarian Transposition in a Young Girl with Primitive Neuroectodermal Tumor of Bladder
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - August 23, 2018 Category: Cancer & Oncology Source Type: research

Chemo-Radiation After Upfront Rectal Resections —a Clinical Dilemma
AbstractTo compare the impact of adjuvant chemo-radiotherapy (ACRT) versus adjuvant chemotherapy (ACT) alone on recurrence and survival in patients with stage II and III rectal adenocarcinoma undergoing upfront curative resection. Prospective observational review of colorectal database at Tata Memorial Hospital from July 2010 to March 2015 identified 84 patients who underwent upfront curative resection for stage II or III rectal cancer. None of the patient received preoperative chemo-radiation. Of these, adjuvant chemo-radiotherapy was administered to 29 patients (ACRT group) and 55 patients received CAPEOX/FOLFOX-based ad...
Source: Indian Journal of Surgical Oncology - August 18, 2018 Category: Cancer & Oncology Source Type: research

From the Desk of the Editor
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - August 15, 2018 Category: Cancer & Oncology Source Type: research

Current Status of Lymphadenectomy During Radical Nephroureterectomy for Upper Tract Urothelial Cancer —Yes, No or Maybe?
This article elucidates the current knowledge on outcomes, benefits and complications of template-based lymphadenectomy during radical nephroureterectomy for UTUC. We also explore the current evidence-based guidelines on this controversial topic. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - August 13, 2018 Category: Cancer & Oncology Source Type: research

Encapsulated Follicular Variant of Papillary Thyroid Carcinoma Arising in a Follicular Adenoma: a Diagnostic Dilemma
AbstractPapillary thyroid carcinoma (PTC) arising within follicular adenoma is a rare histological subset of papillary carcinoma. A 24-year-old female (euthyroid and asymptomatic) presented with a solitary mass in the right lobe of thyroid for 2  years. Fine-needle aspiration cytology (FNAC) suggested features of hyperplasia of thyroid. Hemithyroidectomy was performed. Histopathological examination revealed two distinct areas and was reported as encapsulated variant of papillary carcinoma along with follicular adenoma. Papillary carcinoma was confirmed by positive immunohistochemistry for HBME-1. CT head and neck regi...
Source: Indian Journal of Surgical Oncology - August 13, 2018 Category: Cancer & Oncology Source Type: research

Resection of Isolated Port Site Metastasis in Gall Bladder Cancers —Careful Selection and Perioperative Systemic Therapy May Improve Outcomes
AbstractExcision of port site (PSE) for patients having undergone laparoscopic cholecystectomy (LC) is not a standard recommendation. We retrospectively evaluated a cohort of patients with isolated PSM without any prior cancer-directed therapy who were assessed for resection between March 2012 and July 2016 at Tata Memorial Hospital, Mumbai. Eleven of a total 13 patients underwent wide excision for PSM in the given time period. Upfront resection was undertaken in six patients while seven patients received neoadjuvant chemotherapy (NACT) and two received neoadjuvant chemo radiotherapy (NACTRT) prior to attempted resection. ...
Source: Indian Journal of Surgical Oncology - August 10, 2018 Category: Cancer & Oncology Source Type: research

Completion Total Laryngectomy Ten Years After Near Total Laryngectomy for Radiorecurrent Cancer of the Glottis
AbstractNear total laryngectomy (NTL) is a safe alternative to total laryngectomy in salvaging lateralized radiation failures. A 65-year-old gentleman with radiorecurrent T1 vocal cord cancer was salvaged successfully by NTL. Ten years later, he presented with a strained shunt speech which was treated judiciously, with the aid of a positron emission tomography (PET) scan, by a (completion) total laryngectomy (TL), bilateral selective neck dissection, and pharyngeal resurfacing with pectoralis major myocutaneous (PMMC) flap. The patient is on close follow-up after the second salvage procedure, for 20  months without an...
Source: Indian Journal of Surgical Oncology - August 9, 2018 Category: Cancer & Oncology Source Type: research

Primary Appendicular Malignancy Presenting as Abdominal Wall Abscess with Secondary Tuberculosis Infection: an Interesting Case Report
AbstractCancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of the appendix are only 0.08% of all cancers, and the treatment remains controversial. It can present as appendicitis or lump or abscess. Gastrointestinal tuberculosis most commonly involves the ileocecal region. Disruption of the integrity of mucosal barriers and impairment in cell-mediated immunity associated with cancerous growth are known to predispose to bacterial infection. The role of antituberculosis ...
Source: Indian Journal of Surgical Oncology - August 7, 2018 Category: Cancer & Oncology Source Type: research

Transanal Total Mesorectal Excision for Treatment of Carcinoma in the Middle or Lower Third Rectum: the Technical Feasibility of the Procedure, Pathological Results, and Clinical Outcome
This study included 25 consecutive patients who underwent TaTME for the mid and low cancer rectum. The primary outcome measures included frequency of postoperative (PO) bleeding, leakage, ileus, days to regain bowel function, days for Foley ’s removal, and erectile function. The secondary outcome measures included operation time, status of resection margins, number, the quality of TME, and duration PO hospital stay. No recorded intraoperative complications. The mean hospital stay was 6.9 ± 2.6 days. The mean duration need for u rinary catheter removal and flatus passage were 2.4 &plus...
Source: Indian Journal of Surgical Oncology - August 4, 2018 Category: Cancer & Oncology Source Type: research

Carcinosarcoma of Tongue with Predominant Osteosarcomatous Component
We report a case of carcinosarcoma of tongue in a 51-year-old male with predominant osteosarcomatous and squamous cell carcinoma components. There was no evidence of regional or systemic metastatic disease. This case represents the first reported example of this unusual neoplasm with a predominant osteosarcomatous component, arising in the tongue. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - August 3, 2018 Category: Cancer & Oncology Source Type: research

Clinical Utility of Staging Laparoscopy for Advanced Obstructing Rectal Adenocarcinoma: Emerging Tool
This study aims to evaluate the clinical value of SL in treatment decision-making for advanced rectal cancer (RC) with near or complete obstructing tumors. Observational review of colorectal database at Tata Memorial Hospital from January 2013 to December 2016 identified 562 patients diagnosed and treated for advanced RC. Of the 562 cases, 48.7% (274) were clinically and radiologically diagnosed of near or complete obstructing advanced RC. Medical records of 34% (94/274) who underwent SL with diversion stoma (DS) were analyzed. In the absence of ascites, extensive peritoneal deposits, and unresectable liver metastases on S...
Source: Indian Journal of Surgical Oncology - August 2, 2018 Category: Cancer & Oncology Source Type: research

Safety and Efficacy of Low-Dose Single-Agent Capecitabine in Inoperable Gallbladder Cancer with Jaundice Post-Single-System Single-Catheter External Biliary Drainage: a Pilot Study from a Highly Endemic Area
AbstractGallbladder cancer (CaGB) in the subcontinent belongs to low socioeconomic status, and at the time of diagnosis, a large number is unresectable or inoperable so the palliative treatment remains the only option. In the present study, attempt was made to see the effect and safety profile of single-agent oral capecitabine in inoperable CaGB in presence of low levels of jaundice post-single-catheter transhepatic external biliary drainage. InN = 35 of inoperable jaundiced CaGB, post-biliary drainage capecitabine in low dose was started when their total bilirubin levels fell to 10 mg% or below. Post-ex...
Source: Indian Journal of Surgical Oncology - July 31, 2018 Category: Cancer & Oncology Source Type: research

P-Glycoprotein Expression in Indian Breast Cancer Patients with Reference to Molecular Subtypes and Response to Anthracycline-Based Chemotherapy —a Prospective Clinical Study from a Developing Country
AbstractChemo-resistance is an important factor determining the response of tumor to neoadjuvant chemotherapy (NACT). Our study was aimed to determine the role of P-glycoprotein (P-glyp) expression as a predictor of response to NACT in locally advanced breast cancer (LABC) patients with special reference to molecular subtypes. Sixty cases of locally advanced breast cancer (LABC) were subjected to trucut biopsy and the tissue samples were evaluated immunohistochemically for P-glyp, ER, PR, and Her 2 neu status. Pre- and post-NACT P-glyp expression was correlated with clinical response (using WHO criteria after three cycles ...
Source: Indian Journal of Surgical Oncology - July 31, 2018 Category: Cancer & Oncology Source Type: research

Primary Osteosarcoma of the Breast
AbstractExtraskeletal osteosarcomas are extremely rare and account for
Source: Indian Journal of Surgical Oncology - July 30, 2018 Category: Cancer & Oncology Source Type: research

Catheter Fracture of Subclavian Venous Chemoport Device at Costoclavicular Junction: Pinch-off Syndrome
We present a case of a 35-year-old lady, a case of carcinoma breast, who had spontaneous fracture of chemoport access device in subclavian vein at the level of clavicle after four successful cycles of chemotherapy. The fracture was suspected on chest x-ray and was subsequently confirmed on contrast linogram. The patient was successfully managed with endovascular interventional technique without suffering any ill effects. It is a rare presentation of pinch-off syndrome. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - July 30, 2018 Category: Cancer & Oncology Source Type: research