Iatrogenic Breast Lymphoedema: Incidence, Diagnosis, and Associated Risk Factors
This study was a case series analysis, including patients who had wide local excision for primary breast cancer treatment between January 2013 and January 2018. Patients ’ demographics, including age, weight, body mass index (BMI), breast volume, tumour characteristics, and histological findings, were noted. All patients had a clinical assessment and ultrasound scan 6 months and 12 months after surgery, comparing ipsilateral to the contralateral breast skin, sub cutaneous thickness, as well as parenchymal changes. We have included two hundred eighty-six breast cancer; the mean age was 54.7 years SD 17.3, the mean weig...
Source: Indian Journal of Surgical Oncology - March 7, 2023 Category: Cancer & Oncology Source Type: research

Peritoneal Mesothelioma: Systematic Review of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Protocol Outcomes
Abstract Diffuse malignant peritoneal mesothelioma (DMPM) prognosis was improved by the locoregional treatment combining cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). HIPEC is a multiparametric treatment with multiple protocols proposed and reviewed in this work. A systematic review of medical literature was performed according to PRISMA guidelines. The search strategy used “malignant peritoneal mesothelioma” and “HIPEC” as keywords in three databases. Studies were included if reporting precisely the HIPEC regimen and the related outcomes, if comparing regimen, or if reportin...
Source: Indian Journal of Surgical Oncology - March 4, 2023 Category: Cancer & Oncology Source Type: research

External Validation of Briganti and Memorial Sloan-Kettering Cancer Centre Nomograms for Predicting Lymph Node Invasion in the Indian Cohort of Patients with Prostate Cancer
AbstractBriganti and Memorial Sloan-Kettering Cancer Centre (MSKCC) nomograms are the two commonly used models for predicting lymph node invasion (LNI) in patients with prostate cancer. However, they have never been validated in the Indian cohort of patients with prostate cancer. Hence, with this study, we aimed to externally validate Briganti (2012) and MSKCC nomograms in our dataset of patients who underwent robot-assisted radical prostatectomy (RARP). We reviewed our prospectively maintained RARP data to predict the probability of LNI using Briganti (2012) and MSKCC nomograms. The two models were validated by receiv...
Source: Indian Journal of Surgical Oncology - March 4, 2023 Category: Cancer & Oncology Source Type: research

Tumors of the Posterior Elements of the Spine in Children —an Overview
AbstractIn this narrative review, we aim to describe the clinical features, diagnosis, and management of common primary osseous tumors affecting the posterior elements of the spine in children. We searched PubMed, Mendeley, and Google Scholar using the terms primary osseous tumors of the spine in children, tumors of the posterior elements of the spine, and names of individual tumors. The clinical features, investigations, and treatment modalities were analyzed, and a narrative review of the topic was prepared. We have included 54 studies published in the last 20  years. The majority are isolated reports or case series. Tu...
Source: Indian Journal of Surgical Oncology - March 3, 2023 Category: Cancer & Oncology Source Type: research

Retroperitoneal Liposarcoma: Rational Extent of Surgery Tailored to Grade of Malignancy
This study was aimed at determining the indications for combined and organ-preserving operations. The study included 190 patients with retroperitoneal liposarcoma (RLPS). The influence of the following factors on the overall survival (OS) and recurrence-free survival (RFS) were studied: involvement of adjacent organs in the tumor, volume of surgical intervention. OS and RFS were worse in pathologically confirmed visceral invasion in the both RLPS low grade and high grade (p = 0.000). In RLPS low grade, there was no significant difference in OS and RFS between the group of patients who underwent combined surgery without...
Source: Indian Journal of Surgical Oncology - March 2, 2023 Category: Cancer & Oncology Source Type: research

Lymph Node Metastasis and Patterns of Recurrence in Vulvar Carcinoma: 10 Years ’ Single Center Experience
AbstractVulvar carcinoma is a relatively rare malignancy and there is a paucity of data, especially from India and other developing countries regarding the prognostic factors impacting recurrence and survival. A retrospective observational study was conducted in the Department of Gynecologic Oncology at a tertiary care, regional cancer institute, including all patients with carcinoma vulva who underwent surgery between 2009 and 2018. Demographic profile, surgical-pathological information, details of neo-adjuvant chemotherapy, adjuvant radiation and chemotherapy, and peri-operative complications were analyzed. Long-term fol...
Source: Indian Journal of Surgical Oncology - February 28, 2023 Category: Cancer & Oncology Source Type: research

Thyroglossal Duct Cyst Carcinoma: Lessons from a 20-Case Series
ConclusionsTDCC is rare and a disease of young adulthood and usually has good prognosis. It may be a clinical surprise or a small lesion which can be detected with ultrasound and targeted FNAC. There is high rate of concomitant thyroid carcinoma and hence needs careful assessment. Sistrunk ’s procedure with total thyroidectomy either staged or simultaneously has good outcome and permits adjuvant treatment. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - February 28, 2023 Category: Cancer & Oncology Source Type: research

Utility of Single-Stage Nasolabial Flap Reconstruction for Oral Cavity Defects Following Surgery for Oral Cancers and Premalignant Lesions: A Clinical Audit
Abstract An inferiorly based nasolabial flap (NLF) is a versatile flap for various oral cavity defects. However, it generally necessitates a second stage procedure to release the base at 3  weeks following the initial surgery. Reconstruction for oral cavity defects can be done with the inferiorly based nasolabial flap as a single-stage procedure. In this retrospective clinical audit, we analyzed patients who underwent an inferiorly based NLF reconstruction for oral cavity defect from January 2016 to September 2021. We analyzed the various defects for which this flap was used along with the associated complications and ...
Source: Indian Journal of Surgical Oncology - February 27, 2023 Category: Cancer & Oncology Source Type: research

How to Develop and Implement Computerized Comprehensive Clinical Database in Oncology —the Way Forward
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - February 25, 2023 Category: Cancer & Oncology Source Type: research

Anatomical Description of Anterior Parametrium: A  Probable Answer to Pelvic Recurrence Following Radical Hysterectomy
AbstractA prospective analysis of a retrospective data of patients with cervix carcinoma treated by minimal invasive surgery at high-volume gynecology oncology center analyzing that minimal access surgery is an acceptable treatment modality in cervix carcinoma. The study included 423 patients who underwent laparoscopic/robotic radical hysterectomy after pre-operative evaluation after taking their consent and obtaining ethical approval from the IRB. Post-operatively, patients were followed up at regular intervals for clinical examination and ultrasonography for a median range of 36  months. A PET scan was done only if ther...
Source: Indian Journal of Surgical Oncology - February 24, 2023 Category: Cancer & Oncology Source Type: research

Postmastectomy Immediate Implant-Based Breast Reconstruction with Scarless Latissimus Dorsi Flap —a Simple and Versatile Technique
AbstractIn low- and middle-income countries, breast reconstruction is not widely practiced due to a lack of specialized equipment, skilled personnel, and high costs. The scarless latissimus dorsi flap is a useful technique which can harvest a major portion of the latissimus dorsi muscle using the same mastectomy incision without requiring repositioning of the patient, to cover the lower pole of prosthesis for reconstruction. The aim of this study was to assess and evaluate the cosmetic results and complications of scarless LD flap used as a lower pole cover in post-mastectomy breast reconstruction with implants. This is a ...
Source: Indian Journal of Surgical Oncology - February 22, 2023 Category: Cancer & Oncology Source Type: research

Patient Perspectives After Surgery-Related Complications Among Breast Cancer Patients from a LMIC
AbstractLong-term quality of life in breast cancer patients has been studied and published regularly. However, the lived experiences of patients who develop complications after surgery are not well understood. Determining this experience of patients is challenging in most low- and middle-income countries where the majority of patients belong to poor strata of society and are uneducated. We aimed to explore the thoughts, feelings, and experiences of patients with surgery-related complications after breast cancer surgery. Purposive sampling was used to identify patients who developed any postoperative complication, and s...
Source: Indian Journal of Surgical Oncology - February 21, 2023 Category: Cancer & Oncology Source Type: research

A Fast and Cheap Method for Orienting Breast Lumpectomy Surgical Samples Before Specimen Mammography
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - February 18, 2023 Category: Cancer & Oncology Source Type: research

Enzalutamide-Induced Acute Maculopapular Rash in Treatment of Metastatic Prostate Cancer: First Case Report from a Tertiary Cancer Care Center of North India
In this report, Enzalutamide was withheld for 10 days and anti-histaminics was instituted. After a full recovery, Enzalutamide was reinsti tuted in treatment. A 62-year-old male patient with no significant medical history, was diagnosed in March 2020 with metastatic prostatic adenocarcinoma. Baseline PSA was 456 ng/ml. PSMA PET scan showed evidence of multiple bony metastasis. He was started on Degarelix subcutaneous injection with or al abiraterone initially. PSA level showed initial decreasing trend till September 2021 followed by sudden increase. Intramuscular Injection leuprolide was started and initial responses were...
Source: Indian Journal of Surgical Oncology - February 17, 2023 Category: Cancer & Oncology Source Type: research

A Rare Case of Muco-epidermoid Carcinoma Parotid in a 6-Year-Old Girl and Review of Literature
AbstractMucoepidermoid carcinoma (MEC) is the commonest malignant salivary gland tumor affecting the parotid gland in adults and children. In children and adolescents, there is a peak incidence in the second decade. We came across a 6-year-old girl with intermediate-grade MEC parotid gland, which is very unusual below 10 years of age. A global literature search revealed only 3 other similar cases in children below 10 years of age. She presented with a 2-year history of left parotid gradually increasing hard swelling involving the overlying skin and underlying sternocleidomastoid muscle which was confirmed on a contrast-enh...
Source: Indian Journal of Surgical Oncology - February 15, 2023 Category: Cancer & Oncology Source Type: research