Feasibility of Hepatic Artery Infusion Chemotherapy for Colorectal Liver Metastasis in an Indian Setting
AbstractHepatic artery infusion chemotherapy (HAIC) is a popular treatment modality for the treatment of colorectal liver metastasis (CRLM). The aim of this study was to determine the feasibility of HAIC for high-risk resected CRLM delivered using repeated femoral puncture and delivering 5-fluorouracil infusional chemotherapy along with systemic adjuvant chemotherapy. The present study is a retrospective review of a prospectively maintained database. All patients who underwent HAIC for colorectal liver metastases between July 2022 and July 2023 were included. A total of 12 patients were included in the study of which 11 co...
Source: Indian Journal of Surgical Oncology - December 29, 2023 Category: Cancer & Oncology Source Type: research

Down the Memory Lane
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - December 27, 2023 Category: Cancer & Oncology Source Type: research

Association Between Pre-operative 25-Hydroxy Vitamin D Deficiency and Surgical Site Infection After Oral Cavity Oncology Surgery: a Cross-Sectional Study in a Tertiary Cancer Center in Northwestern India
This study highlights the significant association between pre-operative 25-hydroxy vitamin D deficiency and an increased risk of surgical site infections in patients. Vitamin D plays a crucial role in modulating the immune response, promoting antimicrobial peptides, and enhancing wound he aling. These findings support the importance of assessing and addressing vitamin D deficiency in patients scheduled for oral cavity oncology surgery to potentially reduce the incidence of SSIs. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - December 22, 2023 Category: Cancer & Oncology Source Type: research

Audit of Pain Management After Colorectal Surgeries in a Tertiary Care Cancer Hospital
In conclusion, we conclude, that the analgesic efficacy of epidural analgesia was not found to be superior in our study in patients undergoing major colorectal surgeries. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - December 21, 2023 Category: Cancer & Oncology Source Type: research

Pancreaticoduodenectomy with Para-aortic Lymph Node Dissection for Periampullary Cancer
The objective of this study was to assess survival in patients who underwent PD with PALND for pancreatic (PAC) and non-pancreatic (non-PAC) adenocarcinoma.All patients who underwent PD and PALND between 2011 and 2019 were reviewed (n = 114). We looked at the impact of tumor type (PAC versus non-PAC) and pathologically confirmed PALN metastasis (PALNM) on overall survival (OS). Out of 114 patients, PALNM were pathologically confirmed in 17(14.9%) patients. Without PALND, pathological staging would bepN0 in1(0.8%),pN1 in 3(2.5%), andpN2 in 13(11.2%) patients. The 30-day mortality was 3(2.6%) and 65(57%) patients receive...
Source: Indian Journal of Surgical Oncology - December 20, 2023 Category: Cancer & Oncology Source Type: research

My Tribute to Prof. Blumgart
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - December 19, 2023 Category: Cancer & Oncology Source Type: research

Intrapulmonary Ancient Schwannoma: a Rare Tumour
We present a rare case of an intrapulmonary ancient schwannoma in a 34-year-old female patient. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - December 19, 2023 Category: Cancer & Oncology Source Type: research

Primary Right Adrenal Teratoma in a Postmenopausal Female: a Case Report and Review of Literature
We report a rare case of a primary right adrenal teratoma in a postmenopausal female, presenting with abdominal pain. Ultrasound revealed a complex cystic shadow in the perihepatic region superior to the upper pole of the right kidney, which was suggestive of a complex supra-renal space-sequence-occupying lesion. Computerized tomography revealed a large-sized mature single multilobulated complex cystic lesion in the right hypochondrial lumbar region arising from the right adrenal gland. A right-sided transperitoneal adrenalectomy was performed. The resected mass (18 × 13 × 10 cm) was well encapsulated. Cut surfaces showe...
Source: Indian Journal of Surgical Oncology - December 16, 2023 Category: Cancer & Oncology Source Type: research

Clinico-demographic Profile of Carcinoma Urinary Bladder —5-Year Experience from a Tertiary Care Centre of Eastern India
In this study, we analysed the clinico-demographic profile of patients with urinary bladder carcinoma, attending a tertiary care centre in Eastern India over the last 5  years. We analysed the database of Oncology OPD of a tertiary care centre in West Bengal in Eastern India and collected the demographic, clinical and treatment data of urinary bladder carcinoma patients who attended our OPD between 2017 and 2021. The objective was to assess the demographic and cli nical profile of these patients and compare them with those reported from other parts of India as well as the rest of the world. Majority of patients (70%) were...
Source: Indian Journal of Surgical Oncology - December 15, 2023 Category: Cancer & Oncology Source Type: research

Benign Lesion of the Common Bile Duct Mimicking a Malignant Tumor: an Entity Commonly Overdiagnosed Clinically
AbstractAdenomyomatous hyperplasia and adenomyoma are rare benign inflammatory pseudotumors of the gallbladder arising from Rokitansky-Aschoff sinuses. Occurrence of these hyperplastic conditions in the Vaterian and biliary system is extremely rare and is a concern for gastroenterologists and surgeons in distinguishing them from primary malignancies of the biliary system. Definitive diagnosis by imaging or cytopathological examination is difficult; thus, surgical resection becomes the only choice in such cases to relieve the obstruction. Here, we report two extremely rare cases of adenomyomatous hyperplasia of the extrahep...
Source: Indian Journal of Surgical Oncology - December 14, 2023 Category: Cancer & Oncology Source Type: research

Surgical Resection of the Liver Mass with Impending Rupture: Primary Osteosarcoma of Liver —a Histological Surprise and Literature Review
AbstractOsteosarcomas occurring in the extraskeletal system are known as extraskeletal osteosarcomas (ESOS). They are rare, highly malignant tumors, associated with poor prognosis Di et al. World J Clin Cases 11(3):662 –668 (2023). This is a case report of a gentleman nearing 60s with a liver mass with impending rupture. He underwent resection of the liver mass and was diagnosed to have with ESOS. He underwent a right hepatectomy on an urgent basis. He had an uneventful postoperative recovery. The histopathology report showed a poorly differentiated malignant neoplasm consistent with osteosarcoma. The patient is doing w...
Source: Indian Journal of Surgical Oncology - December 12, 2023 Category: Cancer & Oncology Source Type: research

Management of a Rare Challenging Case of Duodenal Ampullary Lipoma
AbstractDuodenal lipoma is a very rare entity with limited case reports present in literature. But duodenal ampullary lipomas are even more rare in nature. Owing to the recent advances in endoscopy and modern imaging techniques, more cases are being diagnosed and treated. However, challenge lies in performing a less invasive and least morbid procedures to treat them surgically in such complex location of tumour. To study the diagnosis and treatment of duodenal ampullary lipoma in a young male patient and challenges faced during surgical management. A 15-year-old young boy presented to us with complaints of intermittent upp...
Source: Indian Journal of Surgical Oncology - December 7, 2023 Category: Cancer & Oncology Source Type: research

Prognostic Implications of Concurrent Ductal Carcinoma In Situ in Invasive Breast Cancer: an Observational Nested Cohort Study from a Regional Cancer Center in India
AbstractDuctal Carcinoma In Situ (DCIS) is not an obligate precursor to invasive breast cancer and can exhibit variations in clinical presentation, genetics, biomarkers, and morphological features. There are contrasting views in literature with regard to prognostic significance of DCIS component in invasive cancer. Hence, this study aimed to evaluate how the co-occurrence of DCIS affects the prognosis of people with invasive breast cancer (IBC). A retrospective nested cohort observational study of patients with invasive breast cancer with and without DCIS component was conducted to compare the types of metastases developed...
Source: Indian Journal of Surgical Oncology - December 4, 2023 Category: Cancer & Oncology Source Type: research

Revisiting the Trans-Sacral Approach for Large Rectal Adenomas, Surgical Technique, and Oncological Outcome: a Case Series
AbstractThe standard oncologic surgeries for rectal carcinoma are radical trans abdominal procedures, However, these radical procedures are not suitable for large rectal adenomas. The transsacral approach for rectal adenoma was first described by Kraske and since then it has been utilized for various benign conditions of low and mid-rectum as well as for certain cancers. We are presenting a series of 5 consecutive cases of trans-sacral resection done in the past 7  years between January, 2016, until June, 2023, at the Department of Surgical Oncology, Cancer Research Institute, HIMS Dehradun, for large mid- and lower recta...
Source: Indian Journal of Surgical Oncology - December 4, 2023 Category: Cancer & Oncology Source Type: research

Germ Cell Tumor Presenting as a Mesenteric Cyst: a Case Report and Literature Review
This study contributes to the limited literature on primary peritoneal YST, discussing clinicopathological parameters and presenting a detailed case. The pathogenesis of extragonadal germ cell tumors, including YST, remains debated, with migration and stagnation of germ cells during embryonic development proposed as a prevalent theory. Histopathological examination of extragonadal YST mirrors gonadal YST, featuring various patterns. Immunohistochemistry, crucial for diagnosis, reveals positive expression for SALL-4, glypican-3, PLAP, AFP, and panCK. SALL-4 emerges as the most sensitive marker for extragonadal YST. This cas...
Source: Indian Journal of Surgical Oncology - November 30, 2023 Category: Cancer & Oncology Source Type: research