HIPECT4 Trial —the Devil Is in the Details! Is Prophylactic HIPEC and Cytoreduction the New Standard of Care for T4 Colorectal Cancer?
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - February 12, 2024 Category: Cancer & Oncology Source Type: research

Feasibility of the ERAS (Enhanced Recovery After Surgery) Protocol in Patients Undergoing Gastrointestinal Cancer Surgeries in a Tertiary Care Hospital —A Prospective Interventional Study
AbstractEnhanced Recovery After Surgery (ERAS) protocols have emerged as a promising approach to optimize perioperative care and improve outcomes in various surgical specialties. Despite feasibility studies on ERAS in various surgeries, there remains a paucity of research focusing on gastrointestinal cancer surgeries in the Indian context. The primary objective is to evaluate the compliance rate of the ERAS protocol and secondary objectives include the compliance rate of individual components of the protocol, the complications, the length of hospital stay, and the challenges faced during implementation in patients undergoi...
Source: Indian Journal of Surgical Oncology - February 12, 2024 Category: Cancer & Oncology Source Type: research

Successful Salvage of Partial Gastric Conduit Necrosis by Primary Anastomosis in a Post-Esophagectomy Patient
We describe a successful case wherein we salvaged a patient following a McKeown esophagectomy and gastric pull-up, who developed partial full-thickness necrosis of the gastric conduit postoperatively, along with pleural and mediastinal sepsis. We managed this situation through thoracic debridement, take-down of the anastomosis, resection of the devitalized segment of the conduit, and primary esophagogastric anastomosis. Conduit perfusion was demonstrated using ICG fluorescent angiography. This case illustrates that, once debridement and sepsis control are achieved, a primary anastomosis, if feasible, can be safely performe...
Source: Indian Journal of Surgical Oncology - February 12, 2024 Category: Cancer & Oncology Source Type: research

Correction to: Audit of Pain Management After Colorectal Surgeries in a Tertiary Care Cancer Hospital
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - February 9, 2024 Category: Cancer & Oncology Source Type: research

BCOR Positive Central Nervous System Neuroepithelial Tumor Masquerading as a Meningioma
We present a case of BCOR-positive CNS tumor in a 3-year-old child who presented with scalp swelling. A differential diagnosis of CNS tumor with BCOR expression should be considered whenever high-grade tumors with histopathological features of glial or ependymal tumors do not express the classical glial markers. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - February 8, 2024 Category: Cancer & Oncology Source Type: research

Squamous Cell Carcinoma of the Middle Ear —A Common Tumor at an Uncommon Site
We present a rare case of squamous cell carcinoma of the middle ear which clinically presented as chronic suppurative otitis media.Therefore, clinicians should have a high index of suspicion for clinically refractive cases of otorrhea, otalgia, excess bleeding, and non-responsiveness to treatment. All polyps and granulation tissue in EAC and middle ear should be submitted for histopathological examination especially in cases refractory to treatment. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - February 8, 2024 Category: Cancer & Oncology Source Type: research

Study of Comparison of Magnetic Resonance Imaging with Surgical and Pathological features in Carcinoma Rectum Patients
AbstractColorectal cancer is the second-most common cancer in the females and third-most common cancer in males worldwide and it is the second-most common cause of mortality. In India, colorectal cancer is the fifth-most common cancer overall, constituting 6.3%. With the advent of high-resolution magnetic resonance imaging (MRI), it has become the investigation of choice for local staging of rectal cancers as well as in predicting the response to neoadjuvant treatment and streamlining the management. The aims and objectives of this study were to compare the results of MRI with surgicopathological findings in carcinoma (Ca)...
Source: Indian Journal of Surgical Oncology - February 7, 2024 Category: Cancer & Oncology Source Type: research

Malignant Transformation of an Ovarian Mature Cystic Teratoma to a Malignant Melanoma
AbstractOvarian mature cystic teratomas comprise tissue derived from all three germ layers and constitute 10 –20% of all ovarian neoplasms. Malignant transformation of mature cystic teratomas (MCT) is very rare with an incidence of 0.17–2%. The most frequently reported malignancies include squamous cell carcinoma and adenocarcinoma. Herein, we describe a case of a 56-year-old female who presented with abdominal pain and underwent total abdominal hysterectomy with bilateral oophorectomy and omentectomy for a ruptured dermoid cyst. Histological examination showed nests of pleomorphic cells with prominent nucleoli and mel...
Source: Indian Journal of Surgical Oncology - February 7, 2024 Category: Cancer & Oncology Source Type: research

Ovarian Germ Cell Tumors in North-Western India: A Comprehensive 3-Year Retrospective Study of 145 Cases at a Tertiary Cancer Hospital
This study seeks to bridge this knowledge gap by examining the prevalence and characteristics of germ cell tumors within a tertiary cancer hospital. In this retrospective analysis, all cases of germ cell tumors diagnosed over a 3-year period in the specified tertiary cancer hospital were included. Cases with incomplete records or inadequate pathological data were excluded. Data encompassing histological subtypes, patient age distribution, clinical presentations, and histopathological features were collected and analyzed. The study comprised 145 cases of germ cell tumors. Teratomas were the most prevalent subtype, with matu...
Source: Indian Journal of Surgical Oncology - February 3, 2024 Category: Cancer & Oncology Source Type: research

Hepatoblastoma Presenting as Rapidly Progressive Abdominal Mass in a Toddler —A Case Report
We report a case of hepatoblastoma in a toddler in view of its diagnostic challenge. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - February 2, 2024 Category: Cancer & Oncology Source Type: research

Neurovascular Structure-Adjacent Frozen-Section Examination (NeuroSAFE) Technique of Nerve-Sparing Robot-Assisted Radical Prostatectomy (RARP) in Indian Scenario: Technique, Feasibility, and Early Outcomes
AbstractPotency and urinary continence are adversely affected post-prostatectomy. The primary objective is oncological safety by ensuring negative surgical margins (NSM) and best functional recovery through nerve preservation in appropriate patients. NeuroSAFE technique of intra-operative frozen-section (IFS) analysis was devised for comprehensive assessment of surgical margins adjacent to the neurovascular tissue surface of the prostate. We analyzed our initial experience with this technique. Five NS-RARPs were performed utilizing the NeuroSAFE technique between October 2021 and February 2022. Patient demographics, diseas...
Source: Indian Journal of Surgical Oncology - February 1, 2024 Category: Cancer & Oncology Source Type: research

Comment on “From ChatGPT to Treatment: the Future of AI and Large Language Models in Surgical Oncology”
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - January 25, 2024 Category: Cancer & Oncology Source Type: research

Artificial Intelligence in Perioperative Planning and Management of Liver Resection
AbstractArtificial intelligence (AI) is a speciality within computer science that deals with creating systems that can replicate the intelligence of a human mind and has problem-solving abilities. AI includes a diverse array of techniques and approaches such as machine learning, neural networks, natural language processing, robotics, and expert systems. An electronic literature search was conducted using the databases of “PubMed” and “Google Scholar”. The period for the search was from 2000 to June 2023. The search terms included “artificial intelligence”, “machine learning”, “liver cancers”, “liver t...
Source: Indian Journal of Surgical Oncology - January 23, 2024 Category: Cancer & Oncology Source Type: research

Quality of Life in Locally Advanced Carcinoma Rectum Patients During Various Phases of NACRT: An Indian Perspective
AbstractIn low- and middle-income countries (LMICs) including India, cancer patients have a poor prognosis because of late diagnosis and cases already grown to advanced stages, low cancer awareness and skewed cancer care facilities. In India, the incidence of colorectal cancer (CRC) is ranked the 4th most common (6.4%) in males and the 5th most common (3.4%) in females. The improvement in the cure rate of rectal cancer has increased life expectancy, and assessment of the quality of life (QoL) in these patients has become a fundamental requirement. Little is known about how the patients perceive these adverse effects during...
Source: Indian Journal of Surgical Oncology - January 23, 2024 Category: Cancer & Oncology Source Type: research

Predictive Value of Preoperative ICG-R15 Testing in Post-hepatectomy Liver Failure Following Major Liver Resection: Indian Experience
AbstractSurgical resection stands as the preeminent therapeutic approach for both primary hepatocellular carcinoma and metastatic liver malignancies. Its efficacy is contingent upon the attainment of a comprehensive excision while ensuring a sufficient future liver remnant (FLR). However, post-hepatectomy liver failure (PHLF) remains a significant challenge, particularly in patients with preexisting liver disease. The present study aims to investigate the predictive value of the preoperative indocyanine green retention test at 15  min (ICG-R15) in identifying patients at risk of PHLF following major liver resection. This ...
Source: Indian Journal of Surgical Oncology - January 23, 2024 Category: Cancer & Oncology Source Type: research