Review of the pharmacological properties of marine macroalgae used in the treatment of diabetes mellitus in Indonesia
This study provides a comprehensive dataset of pharmacological antidiabetic potential of marine macroalgae used for managing DM and reports on preclinical trials that provide pharmacological evidence. Data on the Indonesian marine macroalgae used to lower blood glucose were obtained from online sources. The bioactive chemicals of marine macroalgae have been found efficient at blocking several diabetes enzymes in in-vivo and in-vitro studies, and such chemicals have anti-inflammatory, anti-obesity, antioxidant, and other therapeutic benefits. The Google Scholar was used to search for the pharmacological literature with the ...
Source: Annales Pharmaceutiques Francaises - February 14, 2024 Category: Drugs & Pharmacology Authors: Agung Giri Samudra Agung Endro Nugroho Retno Murwanti Source Type: research
Anthocyanin: A Potential Phytochemical Candidate for the Amelioration of Non-Alcoholic Fatty Liver Disease
Ann Pharm Fr. 2024 Feb 12:S0003-4509(24)00023-3. doi: 10.1016/j.pharma.2024.02.005. Online ahead of print.ABSTRACTNonalcoholic fatty liver disease (NAFLD) is described by too much hepatic fat deposition causing steatosis, which further develops into nonalcoholic steatohepatitis (NASH), defined by necroinflammation and fibrosis, progressing further to hepatic cirrhosis, hepatocellular carcinoma, and liver failure. NAFLD is linked to different aspects of the metabolic syndrome like obesity, insulin resistance, hypertension, and dyslipidemia, and its pathogenesis involves several elements including diet, obesity, disruption o...
Source: Annales Pharmaceutiques Francaises - February 14, 2024 Category: Drugs & Pharmacology Authors: Bitasta Mandal Rakesh Das Sandip Mondal Source Type: research
Review of the pharmacological properties of marine macroalgae used in the treatment of diabetes mellitus in Indonesia
This study provides a comprehensive dataset of pharmacological antidiabetic potential of marine macroalgae used for managing DM and reports on preclinical trials that provide pharmacological evidence. Data on the Indonesian marine macroalgae used to lower blood glucose were obtained from online sources. The bioactive chemicals of marine macroalgae have been found efficient at blocking several diabetes enzymes in in-vivo and in-vitro studies, and such chemicals have anti-inflammatory, anti-obesity, antioxidant, and other therapeutic benefits. The Google Scholar was used to search for the pharmacological literature with the ...
Source: Annales Pharmaceutiques Francaises - February 14, 2024 Category: Drugs & Pharmacology Authors: Agung Giri Samudra Agung Endro Nugroho Retno Murwanti Source Type: research
Anthocyanin: A Potential Phytochemical Candidate for the Amelioration of Non-Alcoholic Fatty Liver Disease
Ann Pharm Fr. 2024 Feb 12:S0003-4509(24)00023-3. doi: 10.1016/j.pharma.2024.02.005. Online ahead of print.ABSTRACTNonalcoholic fatty liver disease (NAFLD) is described by too much hepatic fat deposition causing steatosis, which further develops into nonalcoholic steatohepatitis (NASH), defined by necroinflammation and fibrosis, progressing further to hepatic cirrhosis, hepatocellular carcinoma, and liver failure. NAFLD is linked to different aspects of the metabolic syndrome like obesity, insulin resistance, hypertension, and dyslipidemia, and its pathogenesis involves several elements including diet, obesity, disruption o...
Source: Annales Pharmaceutiques Francaises - February 14, 2024 Category: Drugs & Pharmacology Authors: Bitasta Mandal Rakesh Das Sandip Mondal Source Type: research
Anthocyanin: A Potential Phytochemical Candidate for the Amelioration of Non-Alcoholic Fatty Liver Disease
Ann Pharm Fr. 2024 Feb 12:S0003-4509(24)00023-3. doi: 10.1016/j.pharma.2024.02.005. Online ahead of print.ABSTRACTNonalcoholic fatty liver disease (NAFLD) is described by too much hepatic fat deposition causing steatosis, which further develops into nonalcoholic steatohepatitis (NASH), defined by necroinflammation and fibrosis, progressing further to hepatic cirrhosis, hepatocellular carcinoma, and liver failure. NAFLD is linked to different aspects of the metabolic syndrome like obesity, insulin resistance, hypertension, and dyslipidemia, and its pathogenesis involves several elements including diet, obesity, disruption o...
Source: Annales Pharmaceutiques Francaises - February 14, 2024 Category: Drugs & Pharmacology Authors: Bitasta Mandal Rakesh Das Sandip Mondal Source Type: research
Review of the pharmacological properties of marine macroalgae used in the treatment of diabetes mellitus in Indonesia
This study provides a comprehensive dataset of pharmacological antidiabetic potential of marine macroalgae used for managing DM and reports on preclinical trials that provide pharmacological evidence. Data on the Indonesian marine macroalgae used to lower blood glucose were obtained from online sources. The bioactive chemicals of marine macroalgae have been found efficient at blocking several diabetes enzymes in in-vivo and in-vitro studies, and such chemicals have anti-inflammatory, anti-obesity, antioxidant, and other therapeutic benefits. The Google Scholar was used to search for the pharmacological literature with the ...
Source: Annales Pharmaceutiques Francaises - February 14, 2024 Category: Drugs & Pharmacology Authors: Agung Giri Samudra Agung Endro Nugroho Retno Murwanti Source Type: research
ACD856, a novel positive allosteric modulator of Trk receptors, single ascending doses in healthy subjects: Safety and pharmacokinetics
ConclusionThe prediction proved accurate demonstrating the value of conducting a microdose study prior to ascending dose studies.Trial registrationNCT05783830 March 24, 2023 (microdose study, retrospectively registered) and NCT05077631 October 14, 2021 (single ascending dose study). (Source: European Journal of Clinical Pharmacology)
Source: European Journal of Clinical Pharmacology - February 14, 2024 Category: Drugs & Pharmacology Source Type: research
Quality Assessment of Selected Essential Antimicrobial Drugs from Drug Retail Outlets of Selected Cities in Eastern Ethiopia
The objective of this study was to assess the quality of four commonly used antimicrobials marketed in the cities of Dire Dawa and Jijiga and the town of Togo-Wuchale, which have high potential for illegal drug trade activities in Ethiopia because they are located near the border with Somalia. A total of 54 brands/samples of amoxicillin, amoxicillin/clavulanic acid, ciprofloxacin, and norfloxacin formulations were collected covertly from 43 facilities using a convenience sampling strategy from March 16 to March 29, 2022. The samples were first screened using Global Pharma Health Fund (GPHF)-Minilab protocols and then analy...
Source: Am J Trop Med Hyg - February 13, 2024 Category: Infectious Diseases Authors: Hailu Anjulo Worku Birhane Ariaya Hymete Ayenew Ashenef Source Type: research
Quality Assessment of Selected Essential Antimicrobial Drugs from Drug Retail Outlets of Selected Cities in Eastern Ethiopia
The objective of this study was to assess the quality of four commonly used antimicrobials marketed in the cities of Dire Dawa and Jijiga and the town of Togo-Wuchale, which have high potential for illegal drug trade activities in Ethiopia because they are located near the border with Somalia. A total of 54 brands/samples of amoxicillin, amoxicillin/clavulanic acid, ciprofloxacin, and norfloxacin formulations were collected covertly from 43 facilities using a convenience sampling strategy from March 16 to March 29, 2022. The samples were first screened using Global Pharma Health Fund (GPHF)-Minilab protocols and then analy...
Source: The American Journal of Tropical Medicine and Hygiene - February 13, 2024 Category: Tropical Medicine Authors: Hailu Anjulo Worku Birhane Ariaya Hymete Ayenew Ashenef Source Type: research
Quality Assessment of Selected Essential Antimicrobial Drugs from Drug Retail Outlets of Selected Cities in Eastern Ethiopia
The objective of this study was to assess the quality of four commonly used antimicrobials marketed in the cities of Dire Dawa and Jijiga and the town of Togo-Wuchale, which have high potential for illegal drug trade activities in Ethiopia because they are located near the border with Somalia. A total of 54 brands/samples of amoxicillin, amoxicillin/clavulanic acid, ciprofloxacin, and norfloxacin formulations were collected covertly from 43 facilities using a convenience sampling strategy from March 16 to March 29, 2022. The samples were first screened using Global Pharma Health Fund (GPHF)-Minilab protocols and then analy...
Source: Am J Trop Med Hyg - February 13, 2024 Category: Infectious Diseases Authors: Hailu Anjulo Worku Birhane Ariaya Hymete Ayenew Ashenef Source Type: research
Quality Assessment of Selected Essential Antimicrobial Drugs from Drug Retail Outlets of Selected Cities in Eastern Ethiopia
The objective of this study was to assess the quality of four commonly used antimicrobials marketed in the cities of Dire Dawa and Jijiga and the town of Togo-Wuchale, which have high potential for illegal drug trade activities in Ethiopia because they are located near the border with Somalia. A total of 54 brands/samples of amoxicillin, amoxicillin/clavulanic acid, ciprofloxacin, and norfloxacin formulations were collected covertly from 43 facilities using a convenience sampling strategy from March 16 to March 29, 2022. The samples were first screened using Global Pharma Health Fund (GPHF)-Minilab protocols and then analy...
Source: The American Journal of Tropical Medicine and Hygiene - February 13, 2024 Category: Tropical Medicine Authors: Hailu Anjulo Worku Birhane Ariaya Hymete Ayenew Ashenef Source Type: research
Quality Assessment of Selected Essential Antimicrobial Drugs from Drug Retail Outlets of Selected Cities in Eastern Ethiopia
The objective of this study was to assess the quality of four commonly used antimicrobials marketed in the cities of Dire Dawa and Jijiga and the town of Togo-Wuchale, which have high potential for illegal drug trade activities in Ethiopia because they are located near the border with Somalia. A total of 54 brands/samples of amoxicillin, amoxicillin/clavulanic acid, ciprofloxacin, and norfloxacin formulations were collected covertly from 43 facilities using a convenience sampling strategy from March 16 to March 29, 2022. The samples were first screened using Global Pharma Health Fund (GPHF)-Minilab protocols and then analy...
Source: Am J Trop Med Hyg - February 13, 2024 Category: Infectious Diseases Authors: Hailu Anjulo Worku Birhane Ariaya Hymete Ayenew Ashenef Source Type: research
Quality Assessment of Selected Essential Antimicrobial Drugs from Drug Retail Outlets of Selected Cities in Eastern Ethiopia
The objective of this study was to assess the quality of four commonly used antimicrobials marketed in the cities of Dire Dawa and Jijiga and the town of Togo-Wuchale, which have high potential for illegal drug trade activities in Ethiopia because they are located near the border with Somalia. A total of 54 brands/samples of amoxicillin, amoxicillin/clavulanic acid, ciprofloxacin, and norfloxacin formulations were collected covertly from 43 facilities using a convenience sampling strategy from March 16 to March 29, 2022. The samples were first screened using Global Pharma Health Fund (GPHF)-Minilab protocols and then analy...
Source: The American Journal of Tropical Medicine and Hygiene - February 13, 2024 Category: Tropical Medicine Authors: Hailu Anjulo Worku Birhane Ariaya Hymete Ayenew Ashenef Source Type: research
Quality Assessment of Selected Essential Antimicrobial Drugs from Drug Retail Outlets of Selected Cities in Eastern Ethiopia
The objective of this study was to assess the quality of four commonly used antimicrobials marketed in the cities of Dire Dawa and Jijiga and the town of Togo-Wuchale, which have high potential for illegal drug trade activities in Ethiopia because they are located near the border with Somalia. A total of 54 brands/samples of amoxicillin, amoxicillin/clavulanic acid, ciprofloxacin, and norfloxacin formulations were collected covertly from 43 facilities using a convenience sampling strategy from March 16 to March 29, 2022. The samples were first screened using Global Pharma Health Fund (GPHF)-Minilab protocols and then analy...
Source: Am J Trop Med Hyg - February 13, 2024 Category: Infectious Diseases Authors: Hailu Anjulo Worku Birhane Ariaya Hymete Ayenew Ashenef Source Type: research
