Reform of early access program in France: impact on workload in a pharmacy and risk identification
Ann Pharm Fr. 2024 Feb 24:S0003-4509(24)00032-4. doi: 10.1016/j.pharma.2024.02.012. Online ahead of print.ABSTRACTThe reform of derogatory access authorisations (DAs) on 1st July 2021 has distorted the routine of the hospital pharmacists dealing with innovative medicines that are waiting for marketing authorization or approval. There are two distinct categories of DAs: Compassionate Access Authorisations (CAAs) are granted by the French National Agency for the Safety of Medicines (ANSM) while Early Access Authorisations (EAPs) are granted at the request of pharmaceutical companies by the French National Authority for Healt...
Source: Annales Pharmaceutiques Francaises - February 26, 2024 Category: Drugs & Pharmacology Authors: Oriane Jouhet Jiyan Demir Marine Sitbon Marc-Antoine Bildan Ariane Bros Esther Kim Nicolas Godron Isabelle Madelaine Laure Deville Source Type: research

Rheum Khorasanicum. L Hydroalcoholic Root Extract Induces Cell Death in Human Colorectal Adenocarcinoma: An in vitro and in silico study
In conclusion, our findings have suggested that high phenol and flavonoid contents of R. khorasanicum root extract possibly play an important role in cell cytotoxicity and apoptosis induction in HT-29 and Caco-2 colon cancer cells.PMID:38408722 | DOI:10.1016/j.pharma.2024.02.013 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - February 26, 2024 Category: Drugs & Pharmacology Authors: Arian Amirkhosravi Mehrnaz Mehrabani Saba Fooladi Mohammad Erfan Nourouzmahani Saeedeh Vasei Yousof Mir Zahra Malekoladi Sanaz Faramarz Mohammad Hadi Nematollahi Mitra Mehrabani Source Type: research

Reform of early access program in France: impact on workload in a pharmacy and risk identification
Ann Pharm Fr. 2024 Feb 24:S0003-4509(24)00032-4. doi: 10.1016/j.pharma.2024.02.012. Online ahead of print.ABSTRACTThe reform of derogatory access authorisations (DAs) on 1st July 2021 has distorted the routine of the hospital pharmacists dealing with innovative medicines that are waiting for marketing authorization or approval. There are two distinct categories of DAs: Compassionate Access Authorisations (CAAs) are granted by the French National Agency for the Safety of Medicines (ANSM) while Early Access Authorisations (EAPs) are granted at the request of pharmaceutical companies by the French National Authority for Healt...
Source: Annales Pharmaceutiques Francaises - February 26, 2024 Category: Drugs & Pharmacology Authors: Oriane Jouhet Jiyan Demir Marine Sitbon Marc-Antoine Bildan Ariane Bros Esther Kim Nicolas Godron Isabelle Madelaine Laure Deville Source Type: research

Rheum Khorasanicum. L Hydroalcoholic Root Extract Induces Cell Death in Human Colorectal Adenocarcinoma: An in vitro and in silico study
In conclusion, our findings have suggested that high phenol and flavonoid contents of R. khorasanicum root extract possibly play an important role in cell cytotoxicity and apoptosis induction in HT-29 and Caco-2 colon cancer cells.PMID:38408722 | DOI:10.1016/j.pharma.2024.02.013 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - February 26, 2024 Category: Drugs & Pharmacology Authors: Arian Amirkhosravi Mehrnaz Mehrabani Saba Fooladi Mohammad Erfan Nourouzmahani Saeedeh Vasei Yousof Mir Zahra Malekoladi Sanaz Faramarz Mohammad Hadi Nematollahi Mitra Mehrabani Source Type: research

Reform of early access program in France: impact on workload in a pharmacy and risk identification
Ann Pharm Fr. 2024 Feb 24:S0003-4509(24)00032-4. doi: 10.1016/j.pharma.2024.02.012. Online ahead of print.ABSTRACTThe reform of derogatory access authorisations (DAs) on 1st July 2021 has distorted the routine of the hospital pharmacists dealing with innovative medicines that are waiting for marketing authorization or approval. There are two distinct categories of DAs: Compassionate Access Authorisations (CAAs) are granted by the French National Agency for the Safety of Medicines (ANSM) while Early Access Authorisations (EAPs) are granted at the request of pharmaceutical companies by the French National Authority for Healt...
Source: Annales Pharmaceutiques Francaises - February 26, 2024 Category: Drugs & Pharmacology Authors: Oriane Jouhet Jiyan Demir Marine Sitbon Marc-Antoine Bildan Ariane Bros Esther Kim Nicolas Godron Isabelle Madelaine Laure Deville Source Type: research

Reform of early access program in France: impact on workload in a pharmacy and risk identification
Ann Pharm Fr. 2024 Feb 24:S0003-4509(24)00032-4. doi: 10.1016/j.pharma.2024.02.012. Online ahead of print.ABSTRACTThe reform of derogatory access authorisations (DAs) on 1st July 2021 has distorted the routine of the hospital pharmacists dealing with innovative medicines that are waiting for marketing authorization or approval. There are two distinct categories of DAs: Compassionate Access Authorisations (CAAs) are granted by the French National Agency for the Safety of Medicines (ANSM) while Early Access Authorisations (EAPs) are granted at the request of pharmaceutical companies by the French National Authority for Healt...
Source: Annales Pharmaceutiques Francaises - February 26, 2024 Category: Drugs & Pharmacology Authors: Oriane Jouhet Jiyan Demir Marine Sitbon Marc-Antoine Bildan Ariane Bros Esther Kim Nicolas Godron Isabelle Madelaine Laure Deville Source Type: research

Rheum Khorasanicum. L Hydroalcoholic Root Extract Induces Cell Death in Human Colorectal Adenocarcinoma: An in vitro and in silico study
In conclusion, our findings have suggested that high phenol and flavonoid contents of R. khorasanicum root extract possibly play an important role in cell cytotoxicity and apoptosis induction in HT-29 and Caco-2 colon cancer cells.PMID:38408722 | DOI:10.1016/j.pharma.2024.02.013 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - February 26, 2024 Category: Drugs & Pharmacology Authors: Arian Amirkhosravi Mehrnaz Mehrabani Saba Fooladi Mohammad Erfan Nourouzmahani Saeedeh Vasei Yousof Mir Zahra Malekoladi Sanaz Faramarz Mohammad Hadi Nematollahi Mitra Mehrabani Source Type: research

Rheum Khorasanicum. L Hydroalcoholic Root Extract Induces Cell Death in Human Colorectal Adenocarcinoma: An in vitro and in silico study
In conclusion, our findings have suggested that high phenol and flavonoid contents of R. khorasanicum root extract possibly play an important role in cell cytotoxicity and apoptosis induction in HT-29 and Caco-2 colon cancer cells.PMID:38408722 | DOI:10.1016/j.pharma.2024.02.013 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - February 26, 2024 Category: Drugs & Pharmacology Authors: Arian Amirkhosravi Mehrnaz Mehrabani Saba Fooladi Mohammad Erfan Nourouzmahani Saeedeh Vasei Yousof Mir Zahra Malekoladi Sanaz Faramarz Mohammad Hadi Nematollahi Mitra Mehrabani Source Type: research

Reform of early access program in France: impact on workload in a pharmacy and risk identification
Ann Pharm Fr. 2024 Feb 24:S0003-4509(24)00032-4. doi: 10.1016/j.pharma.2024.02.012. Online ahead of print.ABSTRACTThe reform of derogatory access authorisations (DAs) on 1st July 2021 has distorted the routine of the hospital pharmacists dealing with innovative medicines that are waiting for marketing authorization or approval. There are two distinct categories of DAs: Compassionate Access Authorisations (CAAs) are granted by the French National Agency for the Safety of Medicines (ANSM) while Early Access Authorisations (EAPs) are granted at the request of pharmaceutical companies by the French National Authority for Healt...
Source: Annales Pharmaceutiques Francaises - February 26, 2024 Category: Drugs & Pharmacology Authors: Oriane Jouhet Jiyan Demir Marine Sitbon Marc-Antoine Bildan Ariane Bros Esther Kim Nicolas Godron Isabelle Madelaine Laure Deville Source Type: research

Patented Farnesoid X receptor modulators: a review (2019 – present)
. (Source: Expert Opinion on Therapeutic Patents)
Source: Expert Opinion on Therapeutic Patents - February 26, 2024 Category: Drugs & Pharmacology Authors: Antimo GioielloEmiliano RosatelliBruno Cerraa Laboratory of Medicinal and Advanced Synthetic Chemistry (Lab MASC), Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italyb Tes Pharma, Taverne di Corciano, Perugia, Italy Source Type: research

Overview of hospital city repay for paediatric preparations initiated within the marseille public university hospital system
Conclusions : The lack of clear and complete hospital prescriptions makes it difficult to carry out treatment initiated in hospital in the outpatient setting. The multiplicity of information systems between hospitals and outpatient settings are obstacles to the interoperability needed to coordinate patient treatment, particularly in paediatrics.. The quality of discharge prescriptions needs to be improved to optimise the patient care pathway.PMID:38387835 | DOI:10.1016/j.pharma.2024.02.009 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - February 22, 2024 Category: Drugs & Pharmacology Authors: Cyrielle Bouguergour Florence Peyron Christophe Curti Nathalie Bailli é S ébastien Gallice Source Type: research

Overview of hospital city repay for paediatric preparations initiated within the marseille public university hospital system
Conclusions : The lack of clear and complete hospital prescriptions makes it difficult to carry out treatment initiated in hospital in the outpatient setting. The multiplicity of information systems between hospitals and outpatient settings are obstacles to the interoperability needed to coordinate patient treatment, particularly in paediatrics.. The quality of discharge prescriptions needs to be improved to optimise the patient care pathway.PMID:38387835 | DOI:10.1016/j.pharma.2024.02.009 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - February 22, 2024 Category: Drugs & Pharmacology Authors: Cyrielle Bouguergour Florence Peyron Christophe Curti Nathalie Bailli é S ébastien Gallice Source Type: research

Overview of hospital city repay for paediatric preparations initiated within the marseille public university hospital system
Conclusions : The lack of clear and complete hospital prescriptions makes it difficult to carry out treatment initiated in hospital in the outpatient setting. The multiplicity of information systems between hospitals and outpatient settings are obstacles to the interoperability needed to coordinate patient treatment, particularly in paediatrics.. The quality of discharge prescriptions needs to be improved to optimise the patient care pathway.PMID:38387835 | DOI:10.1016/j.pharma.2024.02.009 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - February 22, 2024 Category: Drugs & Pharmacology Authors: Cyrielle Bouguergour Florence Peyron Christophe Curti Nathalie Bailli é S ébastien Gallice Source Type: research

Overview of hospital city repay for paediatric preparations initiated within the marseille public university hospital system
Conclusions : The lack of clear and complete hospital prescriptions makes it difficult to carry out treatment initiated in hospital in the outpatient setting. The multiplicity of information systems between hospitals and outpatient settings are obstacles to the interoperability needed to coordinate patient treatment, particularly in paediatrics.. The quality of discharge prescriptions needs to be improved to optimise the patient care pathway.PMID:38387835 | DOI:10.1016/j.pharma.2024.02.009 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - February 22, 2024 Category: Drugs & Pharmacology Authors: Cyrielle Bouguergour Florence Peyron Christophe Curti Nathalie Bailli é S ébastien Gallice Source Type: research

L'effet du safran et de ses extraits sur le traitement du cancer du sein: une revue narrative
Ann Pharm Fr. 2024 Feb 15:S0003-4509(24)00031-2. doi: 10.1016/j.pharma.2024.02.011. Online ahead of print.ABSTRACTBreast cancer (BC) is the most prevalent malignancy in women and the second most common disease worldwide, affecting approximately one million individuals annually. Despite the efficacy of conventional chemotherapy, medication resistance and adverse effects limit its effectiveness, leading researchers to explore alternative treatments, including herbal remedies. Saffron, a well-known spice derived from the Crocus sativus L. plant, has shown potential as a BC treatment. The active components of saffron exhibit a...
Source: Annales Pharmaceutiques Francaises - February 17, 2024 Category: Drugs & Pharmacology Authors: Roya Mokhtarian Soodeh Rajabi Setareh Zahedian Saeideh Jafarinejad-Farsangi Morteza Hadizadeh Masoumeh Sadeghinejad Source Type: research