Augmenting DMTA using predictive AI modelling at AstraZeneca
Drug Discov Today. 2024 Mar 7:103945. doi: 10.1016/j.drudis.2024.103945. Online ahead of print.ABSTRACTDesign-Make-Test-Analyse (DMTA) is the discovery cycle through which molecules are designed, synthesised, and assayed to produce data that in turn are analysed to inform the next iteration. The process is repeated until viable drug candidates are identified, often requiring many cycles before reaching a sweet spot. The advent of artificial intelligence (AI) and cloud computing presents an opportunity to innovate drug discovery to reduce the number of cycles needed to yield a candidate. Here, we present the Predictive Insi...
Source: Drug Discovery Today - March 9, 2024 Category: Drugs & Pharmacology Authors: Gian Marco Emma Evertsson David J Riley Christian Tyrchan Prakash Chandra Rathi Source Type: research

Augmenting DMTA using predictive AI modelling at AstraZeneca
Drug Discov Today. 2024 Mar 7:103945. doi: 10.1016/j.drudis.2024.103945. Online ahead of print.ABSTRACTDesign-Make-Test-Analyse (DMTA) is the discovery cycle through which molecules are designed, synthesised, and assayed to produce data that in turn are analysed to inform the next iteration. The process is repeated until viable drug candidates are identified, often requiring many cycles before reaching a sweet spot. The advent of artificial intelligence (AI) and cloud computing presents an opportunity to innovate drug discovery to reduce the number of cycles needed to yield a candidate. Here, we present the Predictive Insi...
Source: Drug Discovery Today - March 9, 2024 Category: Drugs & Pharmacology Authors: Gian Marco Emma Evertsson David J Riley Christian Tyrchan Prakash Chandra Rathi Source Type: research

Augmenting DMTA using predictive AI modelling at AstraZeneca
Drug Discov Today. 2024 Mar 7:103945. doi: 10.1016/j.drudis.2024.103945. Online ahead of print.ABSTRACTDesign-Make-Test-Analyse (DMTA) is the discovery cycle through which molecules are designed, synthesised, and assayed to produce data that in turn are analysed to inform the next iteration. The process is repeated until viable drug candidates are identified, often requiring many cycles before reaching a sweet spot. The advent of artificial intelligence (AI) and cloud computing presents an opportunity to innovate drug discovery to reduce the number of cycles needed to yield a candidate. Here, we present the Predictive Insi...
Source: Drug Discovery Today - March 9, 2024 Category: Drugs & Pharmacology Authors: Gian Marco Emma Evertsson David J Riley Christian Tyrchan Prakash Chandra Rathi Source Type: research

Augmenting DMTA using predictive AI modelling at AstraZeneca
Drug Discov Today. 2024 Mar 7:103945. doi: 10.1016/j.drudis.2024.103945. Online ahead of print.ABSTRACTDesign-Make-Test-Analyse (DMTA) is the discovery cycle through which molecules are designed, synthesised, and assayed to produce data that in turn are analysed to inform the next iteration. The process is repeated until viable drug candidates are identified, often requiring many cycles before reaching a sweet spot. The advent of artificial intelligence (AI) and cloud computing presents an opportunity to innovate drug discovery to reduce the number of cycles needed to yield a candidate. Here, we present the Predictive Insi...
Source: Drug Discovery Today - March 9, 2024 Category: Drugs & Pharmacology Authors: Gian Marco Emma Evertsson David J Riley Christian Tyrchan Prakash Chandra Rathi Source Type: research

Influence of E-Learning on Pharmacy Students' Learning During the COVID Pandemic: A Survsey Among Pharmacy Students in Morocco
Conclusion: E-learning has significant potential to transform teaching and learning in pharmacy, and its thoughtful integration can bring lasting benefits to students.PMID:38447876 | DOI:10.1016/j.pharma.2024.02.014 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Abdelhafid Benomar Ali Cherif Chefchaouni Younes Rahali Yassir El Alaoui Source Type: research

Strategy to secure the neuraxial route in Anaesthesia: risk mapping and feedback from the application of the ISO 80369-6 standard NRFit ® connectors
CONCLUSION: This work is the first step of the project to prevent administration route error in Anesthesia during patient's drug management. The next step will be the NRFit® implementation for epidural and combined spinal epidural anesthesia in our hospital.PMID:38447875 | DOI:10.1016/j.pharma.2024.02.015 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Jeanice Amiot Marie H élène Bruge Ansel Mathilde Bruyas Marc Rinaudo Emilie Rulliat J érôme Gauthier Vincent Piriou Delphine Cabelguenne Source Type: research

Strategy to secure the neuraxial route in Anaesthesia: risk mapping and feedback from the application of the ISO 80369-6 standard NRFit ® connectors
CONCLUSION: This work is the first step of the project to prevent administration route error in Anesthesia during patient's drug management. The next step will be the NRFit® implementation for epidural and combined spinal epidural anesthesia in our hospital.PMID:38447875 | DOI:10.1016/j.pharma.2024.02.015 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Jeanice Amiot Marie H élène Bruge Ansel Mathilde Bruyas Marc Rinaudo Emilie Rulliat J érôme Gauthier Vincent Piriou Delphine Cabelguenne Source Type: research

Influence of E-Learning on Pharmacy Students' Learning During the COVID Pandemic: A Survsey Among Pharmacy Students in Morocco
Conclusion: E-learning has significant potential to transform teaching and learning in pharmacy, and its thoughtful integration can bring lasting benefits to students.PMID:38447876 | DOI:10.1016/j.pharma.2024.02.014 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Abdelhafid Benomar Ali Cherif Chefchaouni Younes Rahali Yassir El Alaoui Source Type: research

Strategy to secure the neuraxial route in Anaesthesia: risk mapping and feedback from the application of the ISO 80369-6 standard NRFit ® connectors
CONCLUSION: This work is the first step of the project to prevent administration route error in Anesthesia during patient's drug management. The next step will be the NRFit® implementation for epidural and combined spinal epidural anesthesia in our hospital.PMID:38447875 | DOI:10.1016/j.pharma.2024.02.015 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Jeanice Amiot Marie H élène Bruge Ansel Mathilde Bruyas Marc Rinaudo Emilie Rulliat J érôme Gauthier Vincent Piriou Delphine Cabelguenne Source Type: research

Influence of E-Learning on Pharmacy Students' Learning During the COVID Pandemic: A Survsey Among Pharmacy Students in Morocco
Conclusion: E-learning has significant potential to transform teaching and learning in pharmacy, and its thoughtful integration can bring lasting benefits to students.PMID:38447876 | DOI:10.1016/j.pharma.2024.02.014 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Abdelhafid Benomar Ali Cherif Chefchaouni Younes Rahali Yassir El Alaoui Source Type: research

Influence of E-Learning on Pharmacy Students' Learning During the COVID Pandemic: A Survsey Among Pharmacy Students in Morocco
Conclusion: E-learning has significant potential to transform teaching and learning in pharmacy, and its thoughtful integration can bring lasting benefits to students.PMID:38447876 | DOI:10.1016/j.pharma.2024.02.014 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Abdelhafid Benomar Ali Cherif Chefchaouni Younes Rahali Yassir El Alaoui Source Type: research

Strategy to secure the neuraxial route in Anaesthesia: risk mapping and feedback from the application of the ISO 80369-6 standard NRFit ® connectors
CONCLUSION: This work is the first step of the project to prevent administration route error in Anesthesia during patient's drug management. The next step will be the NRFit® implementation for epidural and combined spinal epidural anesthesia in our hospital.PMID:38447875 | DOI:10.1016/j.pharma.2024.02.015 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Jeanice Amiot Marie H élène Bruge Ansel Mathilde Bruyas Marc Rinaudo Emilie Rulliat J érôme Gauthier Vincent Piriou Delphine Cabelguenne Source Type: research

Strategy to secure the neuraxial route in Anaesthesia: risk mapping and feedback from the application of the ISO 80369-6 standard NRFit ® connectors
CONCLUSION: This work is the first step of the project to prevent administration route error in Anesthesia during patient's drug management. The next step will be the NRFit® implementation for epidural and combined spinal epidural anesthesia in our hospital.PMID:38447875 | DOI:10.1016/j.pharma.2024.02.015 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Jeanice Amiot Marie H élène Bruge Ansel Mathilde Bruyas Marc Rinaudo Emilie Rulliat J érôme Gauthier Vincent Piriou Delphine Cabelguenne Source Type: research

Influence of E-Learning on Pharmacy Students' Learning During the COVID Pandemic: A Survsey Among Pharmacy Students in Morocco
Conclusion: E-learning has significant potential to transform teaching and learning in pharmacy, and its thoughtful integration can bring lasting benefits to students.PMID:38447876 | DOI:10.1016/j.pharma.2024.02.014 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - March 6, 2024 Category: Drugs & Pharmacology Authors: Abdelhafid Benomar Ali Cherif Chefchaouni Younes Rahali Yassir El Alaoui Source Type: research

Association of COVID-19 vaccination with duration of hospitalization in older adults in Hong Kong
CONCLUSION: Vaccination was associated with reduced hospital stay in breakthrough infections. Increased vaccination uptake in older adults may improve hospital bed turnover and public health outcomes especially during large community epidemics.PMID:38448323 | DOI:10.1016/j.vaccine.2024.02.074 (Source: Vaccine)
Source: Vaccine - March 6, 2024 Category: Allergy & Immunology Authors: Dongxuan Chen Benjamin J Cowling Kylie E C Ainslie Yun Lin Jessica Y Wong Eric H Y Lau Peng Wu Joshua Nealon Source Type: research