Comparative study of production and control processes of parenteral nutritional admixtures in neonatology.
CONCLUSION: The diversity of NP practices has a real impact on the quality of the preparations made. A regional collaboration should be envisaged to standardise patient care.PMID:38159720 | DOI:10.1016/j.pharma.2023.12.009 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 30, 2023 Category: Drugs & Pharmacology Authors: Aliz ée Bosson Marjorie Durand Roseline Mazet Mireille Jouannet Romaszko Philip Chennell Freddy Mounsef Thierry Quessada Luc Choisnard Pierrick Bedouch Source Type: research

Assessment of prices, availability and affordability of essential medicines in Juba County, South Sudan
ConclusionsIn South Sudan, medicines are poorly available in all sectors. Medicines are affordable in the public sector but Most medicines are unaffordable in private pharmacies, private clinics and faith-based health facilities. Poor medicines availability in the public sector contributes to the overall unaffordability of medicines in all the other sectors. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - December 30, 2023 Category: Pharmaceuticals Source Type: research

Optimizing pharmaceutical management of clinical trials
CONCLUSION: Changes could be made in the routine practice of the clinical trials pharmacists to improve the management of studies, while the number of trials is increasing every year.PMID:38157980 | DOI:10.1016/j.pharma.2023.12.010 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 29, 2023 Category: Drugs & Pharmacology Authors: Akram Farhat Aline Voidey Isabelle Sommer Laurent Carrez Farshid Sadeghipour Source Type: research

Pharmacist-led vaccination services in the Middle East
AbstractSuccessful Vaccine uptake relies heavily on the effectiveness of vaccination services. Expanding the scope of pharmacists ’ involvement in vaccination services can significantly improve vaccination coverage. The level of pharmacists’ engagement in immunization services varies globally. The aim of this paper is to describe the current role of pharmacists in vaccination services in the Middle Eastern countries. The p rovision of vaccination services by pharmacists in the region has evolved notably in recent years. The extent of pharmacists’ involvement in immunization services varies from one country to another...
Source: Journal of Pharmaceutical Policy and Practice - December 29, 2023 Category: Pharmaceuticals Source Type: research

Development of the Pharmacist ’s Stress Scale for Home Care (PSS) and evaluation of its reliability and validity
ConclusionsThe scale developed in this study is considered to be useful for the measurement of stress of pharmacists derived from interpersonal work and home care services. Leaving the job and burnout are expected to be prevented by perceiving the stress level of the pharmacists by themselves using this scale and coping with stress. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - December 28, 2023 Category: Pharmaceuticals Source Type: research

An Organocopper(III) Fluoride Triggering C-CF3 Bond Formation
Angew Chem Int Ed Engl. 2023 Dec 26:e202319412. doi: 10.1002/anie.202319412. Online ahead of print.ABSTRACTCopper(III) fluorides are catalytically competent, yet elusive, intermediates in cross-coupling. The synthesis of [PPh4][CuIII(CF3)3F] (2), the first stable (isolable) CuIII-F, was accomplished via chloride addition to [CuIII(CF3)3(py)] (1) yielding [PPh4][CuIII(CF3)3Cl(py)] (1.Cl), followed by treatment with AgF. The CuIII halides 1.Cl and 2 were fully characterized using nuclear magnetic resonance (NMR) spectroscopy, single crystal X-ray diffraction (Sc-XRD) and elemental analysis (EA). Complex 2 proved capable of f...
Source: Angewandte Chemie - December 26, 2023 Category: Chemistry Authors: Daniel Joven-Sancho Andrea Echeverri Nathalie Saffon-Merceron Julia Contreras-Garc ía Noel Nebra Source Type: research

An Organocopper(III) Fluoride Triggering C-CF3 Bond Formation
Angew Chem Int Ed Engl. 2023 Dec 26:e202319412. doi: 10.1002/anie.202319412. Online ahead of print.ABSTRACTCopper(III) fluorides are catalytically competent, yet elusive, intermediates in cross-coupling. The synthesis of [PPh4][CuIII(CF3)3F] (2), the first stable (isolable) CuIII-F, was accomplished via chloride addition to [CuIII(CF3)3(py)] (1) yielding [PPh4][CuIII(CF3)3Cl(py)] (1.Cl), followed by treatment with AgF. The CuIII halides 1.Cl and 2 were fully characterized using nuclear magnetic resonance (NMR) spectroscopy, single crystal X-ray diffraction (Sc-XRD) and elemental analysis (EA). Complex 2 proved capable of f...
Source: Angewandte Chemie - December 26, 2023 Category: Chemistry Authors: Daniel Joven-Sancho Andrea Echeverri Nathalie Saffon-Merceron Julia Contreras-Garc ía Noel Nebra Source Type: research

OPTIMIZING THE USE-BY DATE OF REUSABLE MEDICAL DEVICES - Experience in a healthcare establishment
CONCLUSIONS: The DLU has been extended to 4 months for sachets, 6 months for folded products and maintained at six months for containers.PMID:38135038 | DOI:10.1016/j.pharma.2023.12.007 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Manon Vidor Christelle Raguenes H élène Astier Gilles Gbaguidi Sarah Le Tohic Source Type: research

Research cartography of implantable medical devices in the three Maghreb countries: A comparative study between Morocco, Algeria, and Tunisia
CONCLUSION: The design of maps raises a diversity of fields that concern medical and engineering sciences, while medical economic studies have yet to be developed in all three countries.PMID:38135036 | DOI:10.1016/j.pharma.2023.12.005 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Meryem Qouhafa Brahim Benaji Souad Lebbar Asmaa Marrakchi Abdelmajid Soulaymani Benayad Nsiri My Hachem El Yousfi Alaoui Mokhtari Abdelrhani Mohammed Azougagh Source Type: research

Fabrication of pellets via extrusion-spheronisation for engineered delivery of Famotidine through specialized straws for Paediatrics
CONCLUSION: Finally, the fast-disintegrating pellets demonstrated excellent in vitro performance and relative ease of manufacturing as compared to other solid dosage forms. Furthermore, the developed specialized straw can be used as a convenient and attractive drug delivery device for pediatrics.PMID:38135035 | DOI:10.1016/j.pharma.2023.12.008 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Shweta Purandare Shubham Khot Amelia Avachat Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

Fabrication of pellets via extrusion-spheronisation for engineered delivery of Famotidine through specialized straws for Paediatrics
CONCLUSION: Finally, the fast-disintegrating pellets demonstrated excellent in vitro performance and relative ease of manufacturing as compared to other solid dosage forms. Furthermore, the developed specialized straw can be used as a convenient and attractive drug delivery device for pediatrics.PMID:38135035 | DOI:10.1016/j.pharma.2023.12.008 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Shweta Purandare Shubham Khot Amelia Avachat Source Type: research

Research cartography of implantable medical devices in the Three Maghreb countries: A comparative study between Morocco, Algeria, and Tunisia
CONCLUSION: The design of maps raises a diversity of fields that concern medical and engineering sciences, while medical economic studies have yet to be developed in all three countries.PMID:38135036 | DOI:10.1016/j.pharma.2023.12.005 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Meryem Qouhafa Brahim Benaji Souad Lebbar Asmae Marrakechi Abdelmajid Soulaymani Benayad Nsiri My Hachem El Yousfi Alaoui Mokhtari Abdelrhani Mohammed Azougagh Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

OPTIMIZING THE USE-BY DATE OF REUSABLE MEDICAL DEVICES - Experience in a healthcare establishment
CONCLUSIONS: The DLU has been extended to 4 months for sachets, 6 months for folded products and maintained at six months for containers.PMID:38135038 | DOI:10.1016/j.pharma.2023.12.007 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Manon Vidor Christelle Raguenes H élène Astier Gilles Gbaguidi Sarah Le Tohic Source Type: research