Risk factors for hepatocellular carcinoma associated with hepatitis C genotype 3 infection: A systematic review
CONCLUSION: Although, studies have shown that HCV genotype-3 infection is an independent risk factor for end-stage liver disease, HCC, and liver-related death, there is a lack of evidence for specific risk factors for HCC secondary to HCV genotype-3. Only cirrhosis and age have demonstrated an association; however, the number of studies is very small, and more research is required to investigate risk factors for HCC secondary to HCV genotype-3.PMID:38660636 | PMC:PMC11037048 | DOI:10.4251/wjgo.v16.i4.1596 (Source: Cancer Control)
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Hamzah Z Farooq Michael James Jane Abbott Patrick Oyibo Pip Divall Naheed Choudhry Graham R Foster Source Type: research
A Deeper Depth of Response After Salvage Therapy Improves Outcomes of Autologous Stem Cell Transplantation in Relapsed Lymphoma and the Feasibility of Non-controlled Rate Freezing of Peripheral Blood Stem Cells
Conclusion High-dose therapy and autologous stem cell transplantation in low- to middle-income countries are limited to relatively younger patients, potentially curative conditions such as lymphoma, and predominantly after achieving a complete response to salvage therapy due to limited resources. Due to these factors, our study shows excellent response rates and survival outcomes compared to internationally published data. Engraftment was also excellent and comparable to published data despite the non-controlled rate freezing of peripheral blood stem cells.PMID:38659569 | PMC:PMC11039573 | DOI:10.7759/cureus.56851 (Source: Cancer Control)
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Saif Ur Rab Mussadique Ali Uzma Rasool Mahar Bushra Ahsan Usman Ahmad Muhammad Tariq Mahmood Neelam Siddiqui Syed W Bokhari Source Type: research
China set to fetch first rocks from mysterious far side of the Moon
There’s a giant hole on the backside of the Moon. The South Pole–Aitken (SPA) Basin, the Moon’s largest and oldest impact crater, is more than 2500 kilometers wide and 8 kilometers deep—nearly big enough to swallow two Indias and hide the Himalayas. Now, China plans to land in it.
The basin may have been blasted out during a barrage of asteroids that pummeled Earth and other inner Solar System bodies billions of years ago, and scientists have long wanted to get their hands on SPA rocks to test the idea. The China National Space Administration (CNSA) aims to provide them with the Chang’e-6 mission, which sci...
Source: Science of Aging Knowledge Environment - April 24, 2024 Category: Geriatrics Source Type: research
Environmental Surveillance of Poliovirus and Non-polio Enteroviruses in Iran, 2017 –2023: First Report of Imported Wild Poliovirus Type 1 Since 2000
AbstractIn Iran, which is at high risk of the Wild Poliovirus (WPV) and Vaccine-Derived Poliovirus (VDPV) importation due to its neighborhood with two polio endemic countries, Pakistan and Afghanistan, Environmental Surveillance (ES) was established in November 2017. Sistan-Balouchestan province was chosen for the ES due to its vicinity with Pakistan and Afghanistan. Five sewage collection sites in 4 cities (Zahedan, Zabol, Chabahar and Konarak) were selected in the high-risk areas. Since the establishment of ES in November 2017 till the end of 2023, 364 sewage specimens were collected and analyzed. The ES detected poliovi...
Source: Food and Environmental Virology - April 24, 2024 Category: Virology Source Type: research
Ethnobotanical assessment of antidiabetic medicinal plants in District Karak, Pakistan
Diabetes is a leading health disorder and is responsible for high mortality rates across the globe. Multiple treatment protocols are being applied to overcome this morbidity and mortality including plant-based... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - April 24, 2024 Category: Complementary Medicine Authors: Amina Nazar, Muhammad Adnan, Syed Majid Shah, Ahmed Bari, Riaz Ullah, Akash Tariq and Nisar Ahmad Tags: Research Source Type: research
Oral mucormycosis associated with COVID-19 and diabetes mellitus: Case report and literature review
We present a case of a patient with diabetes mellitus and diagnosed with oral mucormycosis associated with COVID-19.PMID:38648346 | DOI:10.7705/biomedica.6970 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - April 22, 2024 Category: International Medicine & Public Health Authors: Julio C ésar Velasco Ledmar Jovanny Vargas Lorena Garc ía Iv án José Torres Iv án Camilo González Source Type: research
Genomic characterization of human respiratory syncytial virus circulating in Islamabad, Pakistan, during an outbreak in 2022-2023
In this study, conducted at the National Institute of Health, Islamabad, during an outbreak of human respiratory syncytial virus (hRSV) from December 2022 to January 2023, the first whole-genome sequences of hRSV isolates from Islamabad, Pakistan, were determined. Out of 10 positive samples, five were sequenced, revealing the presence of two genotypes: RSV-A (GA2.3.5, ON1 strain) and RSV-B (GB5.0.5.a, BA-10 strain). A rare non-synonymous substitution (E232G) in G the protein and N276S in the F protein were found in RSV-A. In RSV-B, the unique mutations K191R, Q209R, and I206M were found in the F protein. These mutations co...
Source: Archives of Virology - April 22, 2024 Category: Virology Source Type: research
Non-compliant packaging and illicit smokeless tobacco in Bangladesh, India and Pakistan: findings of a pack analysis
Conclusions
Weak and poorly enforced ST control policies may be slowing the progress of tobacco control in South Asia. Standardised regulations are required for packaging and labelling ST. Improving compliance and reducing sale of cheap illicit products may require business licensing and market surveillance. (Source: Tobacco Control)
Source: Tobacco Control - April 19, 2024 Category: Respiratory Medicine Authors: Abdullah, S. M., Huque, R., Siddiqi, K., Kanaan, M., Huque, S., Ullah, S., Garg, S., Singh, M. M., Deshmukh, C., Borle, A. L., Iqbal, R., Mazhar, L., Parascandola, M., Mehrotra, R., Croucher, R., Khan, Z. Tags: Open access Original research Source Type: research
Exploring relationship of poor sleeping habits with prenatal stress among pregnant women in Pakistan: a cross-sectional study
Pregnancy is a complex phenomenon accompanied by biological, physiological and psychosocial changes for a mother. It is also regarded as a stressful life event where a woman ’s role, identity and interpersonal ... (Source: BMC Research Notes)
Source: BMC Research Notes - April 19, 2024 Category: Research Authors: Ahmed Waqas, Irfan Siddique, Mehroz Ahsen, Muhammad Zubair, Mehak Naeem, Aamir Raoof Memon and Sadiq Naveed Tags: Research Note Source Type: research
Ethnic density and first episode psychosis in the British Pakistani population: findings from the East Lancashire Early Intervention Service
CONCLUSIONS: Higher ethnic density related to lower risk of FEP within the Pakistani population in East Lancashire, highlighting the impact of local social context on psychosis incidence.PMID:38634312 | DOI:10.1192/bjp.2024.40 (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 18, 2024 Category: Psychiatry Authors: Robert Qi Masood Qureshi Nadeem Gire Imran B Chaudhry Victoria Vass Jason C McIntyre Kaylee Barlow Richard P Bentall Ross G White Nusrat Husain Source Type: research
An SNP based genotyping assay for genes associated with drought tolerance in bread wheat
CONCLUSION: These findings propose that TaSnRK2.9 can be effectively employed for improving wheat through marker-assisted selection in wheat breeding efforts.PMID:38637351 | DOI:10.1007/s11033-024-09481-x (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 18, 2024 Category: Molecular Biology Authors: Abdul Rauf Muhammad Ali Sher Umar Farooq Awais Rasheed Muhammad Sajjad Ruilian Jing Zulqurnain Khan Kotb A Attia Arif Ahmed Mohammed Sajid Fiaz Jing Chen Shoaib Ur Rehman Source Type: research
Ethnic density and first episode psychosis in the British Pakistani population: findings from the East Lancashire Early Intervention Service
CONCLUSIONS: Higher ethnic density related to lower risk of FEP within the Pakistani population in East Lancashire, highlighting the impact of local social context on psychosis incidence.PMID:38634312 | DOI:10.1192/bjp.2024.40 (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 18, 2024 Category: Psychiatry Authors: Robert Qi Masood Qureshi Nadeem Gire Imran B Chaudhry Victoria Vass Jason C McIntyre Kaylee Barlow Richard P Bentall Ross G White Nusrat Husain Source Type: research
No use of schools: the heterogenous effects of conflict in Pakistan on enrolment rates of boys and girls
Abbas Ali Gillani, Khadija M. Bari Journal of Aggression, Conflict and Peace Research, Vol. ahead-of-print, No. ahead-of-print, pp.- The purpose of this study is to estimate the impact of conflict witnessed in Pakistan on the enrolment rates of boys and girls. Pakistan has the world’s second-highest number of out-of-school children, with an estimated 22.8 million children aged 5–16 years not attending school.By merging data on violence with the data on enrolment rates, this paper finds that exposure to violence is correlated with a decline in overall district-level enrolment rates in the short run at primary-level sch...
Source: Journal of Aggression, Conflict and Peace Research - April 16, 2024 Category: Criminology Authors: Abbas Ali Gillani Khadija M. Bari Source Type: research
Foot-and-mouth disease seroprevalence is higher in young female crossbred sheep and goats compared to their counterparts in the border area between Pakistan and Afghanistan
CONCLUSIONS: This study showed that FMD is highly prevalent in sheep and goats in the border areas of Pakistan and Afghanistan. Therefore, outbreak investigation teams should be arranged at the border level to develop FMD risk-based surveillance and control plans for small ruminants in order to mitigate infection risks.PMID:38626798 | DOI:10.2460/ajvr.23.12.0279 (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - April 16, 2024 Category: Veterinary Research Authors: Abdul Kabir Asghar A Kamboh Muhammad Abubakar Abdulkareem M Matar Kanwar Kumar Source Type: research
