Promoting resilience in children and adolescents living with parental mental illness (CAPRI): children are key to identifying solutions.
Authors: Abel KM, Hope H, Faulds A, Pierce M Abstract SummaryThe lives of Children and Adolescents with PaRental mental Illness (CAPRI) represent a public health priority. Identifying those at most risk within the risk subset is crucial to promote resilience for this group. The ability to develop child-centred interventions will underpin the success of evidence-based services and CAPRI themselves are key to unlocking current service barriers.Declaration interestNone. PMID: 31190644 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Addiction care in crisis: evidence should drive progressive policy and practice.
Authors: Bhui KS, Byrne P, Goslar D, Sinclair J Abstract SummaryAddictions are challenging health and social problems that need to be addressed to preserve and promote good mental health and ensure that individuals within society lead healthy and productive lives. Tackling addictions is complex and requires communities, public health, specialist services, and local and national government to act in unison and implement evidence-based interventions. This editorial raises systemic issues that need attention and proposes a range of systemic options.Declaration of interestK.S.B. is Editor-in-Chief of the British Journa...
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Neighbourhood greenness and depression among older adults.
CONCLUSIONS: Higher levels of greenness may reduce depression odds among older adults. Increasing greenery - even to moderate levels - may enhance individual-level approaches to promoting wellness.Declaration of interestNone. PMID: 31190652 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Recession, recovery and suicide in mental health patients in England: time trend analysis.
CONCLUSIONS: Recession-associated increases in suicide were seen in male mental health patients as well as the male general population, with those in mid-life at particular risk. Support and targeted interventions for patients with financial difficulties may help reduce the risk at times of economic hardship. Factors such as drug and alcohol misuse also need to be considered. Recent decreases in suicide may be related to an improved economic context or better mental healthcare.Declaration of interestN.K. is supported by Greater Manchester Mental Health NHS Foundation Trust. L.A. chairs the National Suicide Prevention Strat...
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Sodium valproate in psychiatric practice: time for a change in perception.
Authors: Owens DC Abstract SummarySodium valproate and related preparations have recently undergone regulatory review following concern about effects on the unborn child and doctors' failure to communicate risk. The issues are wider. Valproate is overused in psychiatry based on the false perception that 'ease' of use equates to better safety than alternatives. Valproic acid can disrupt fundamental physiological processes, the consequences of which are poorly understood and little discussed in the psychiatric literature. Valproate may be useful in a small number of patients with bipolar disorder but current prescrib...
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Consciousness Demystified By Todd E. Feinberg and Jon M. Mallatt. MIT Press. 2018. £20.00 (hb). 208 pp. ISBN 9780262038812.
Consciousness Demystified By Todd E. Feinberg and Jon M. Mallatt. MIT Press. 2018. £20.00 (hb). 208 pp. ISBN 9780262038812. Br J Psychiatry. 2019 Jul;215(1):436 Authors: Cavanna AE PMID: 31196242 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Imagination and Social Perspectives: Approaches from Phenomenology and Psychopathology Edited by Michela Summa, Thomas Fuchs and Luca Vanzago. Routledge. 2017. 358 pp. £125.00 (hb). ISBN 9781138221000.
Imagination and Social Perspectives: Approaches from Phenomenology and Psychopathology Edited by Michela Summa, Thomas Fuchs and Luca Vanzago. Routledge. 2017. 358 pp. £125.00 (hb). ISBN 9781138221000. Br J Psychiatry. 2019 Jul;215(1):436-437 Authors: Oyebode F PMID: 31196243 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The Book of Humans: The Story of How We Became Us By Adam Rutherford. Weidenfeld & Nicolson. 2018. 272 pp. £18.99 (hb). ISBN 9780297609407.
The Book of Humans: The Story of How We Became Us By Adam Rutherford. Weidenfeld & Nicolson. 2018. 272 pp. £18.99 (hb). ISBN 9780297609407. Br J Psychiatry. 2019 Jul;215(1):437 Authors: Adshead G PMID: 31196244 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The Making of Modern Psychiatry By Ronald Chase. Logos Verlag Berlin. 2018. 232 pp. £31.00 (pb). ISBN 9783832547189.
The Making of Modern Psychiatry By Ronald Chase. Logos Verlag Berlin. 2018. 232 pp. £31.00 (pb). ISBN 9783832547189. Br J Psychiatry. 2019 Jul;215(1):437-438 Authors: Hilton C PMID: 31196245 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The challenge of cost-effectiveness research on first-episode psychosis.
Authors: Rosenheck R Abstract SummaryEarly intervention in psychosis has generated hope. Cost-effectiveness studies, to determine whether benefits exceed costs, thus far conclude only that early intervention 'might be' worth its costs. It is a testament to the importance of the question: even in the absence of conclusive data, a synthesis should be attempted.Declaration of interestNone. PMID: 31196246 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The Routledge Handbook of the Computational Mind Edited by Mark Sprevak and Matteo Colombo Routledge. 2018. 510pp. £175 (hb). ISBN 9781138186682.
The Routledge Handbook of the Computational Mind Edited by Mark Sprevak and Matteo Colombo Routledge. 2018. 510pp. £175 (hb). ISBN 9781138186682. Br J Psychiatry. 2019 Jul;215(1):438-439 Authors: Corlett PR PMID: 31196247 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Potential differences in antidepressant effects of oral ketamine liquid suspension versus compounded capsules.
Authors: Rosenblat JD PMID: 31196248 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Kaleidoscope.
Authors: Tracy DK, Joyce DW, Albertson DN, Shergill SS PMID: 31196249 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 15, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

An attempt to explain the bidirectional association between ischaemic heart disease, stroke and depression: a cohort and meta-analytic approach.
CONCLUSIONS: The bidirectional association between CVD and depression was not explained by shared risk factors, misclassification or non-response.Declaration of interestNone. PMID: 31179963 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 12, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

When the drugs don't work: the potential of glutamatergic antipsychotics in schizophrenia - ADDENDUM.
Authors: Papanastasiou E, Stone JM, Shergill S PMID: 31180300 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 12, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Prevalence of serum N-methyl-d-aspartate receptor autoantibodies in refractory psychosis - ADDENDUM.
Authors: Beck K, Lally J, Shergill SS, Bloomfield MAP, MacCabe JH, Gaughran F, Howes OD PMID: 31180301 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 12, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Suicidal behaviour among persons with attention-deficit hyperactivity disorder.
CONCLUSIONS: This study underlines the link between ADHD and an elevated rate of suicidal behaviour, which is significantly elevated by comorbid psychiatric disorders. In sum, these results suggest that persons with ADHD and comorbid psychiatric disorders are targets for suicide preventive interventions.Declaration of interestNone. PMID: 31172893 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 9, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Polygenic effects of schizophrenia on hippocampal grey matter volume and hippocampus-medial prefrontal cortex functional connectivity.
CONCLUSIONS: These findings suggested that genetically influenced brain grey matter volume and functional connectivity may provide important clues for understanding the pathological mechanisms of schizophrenia and for the early diagnosis of schizophrenia.Declaration of interestNone. PMID: 31169117 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 8, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Female survivors of intimate partner violence and risk of depression, anxiety and serious mental illness.
CONCLUSIONS: IPV remains a significant public health issue in the UK. We have demonstrated the significant recorded mental health burden associated with IPV in primary care, at both baseline and following exposure. Clinicians must be aware of this association to reduce mental illness diagnostic delay and improve management of psychological outcomes in this group of patients.Declaration of interestNone. PMID: 31171045 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 8, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Clinical indicators of treatment-resistant psychosis.
CONCLUSIONS: People with an earlier age at onset of psychosis and poor premorbid functioning are more likely to be treatment resistant. The genetic architecture of susceptibility to schizophrenia may be distinct from that of treatment outcomes.Declaration of interestNone. PMID: 31155017 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 5, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Transition between child and adult services for young people with attention-deficit hyperactivity disorder (ADHD): findings from a British national surveillance study.
CONCLUSIONS: As inclusion criteria required participants to be on medication, these estimates represent the lower limit of the transition need. Two critical points were apparent: referral acceptance and first appointment attendance. The low rate of successful transition and limited guideline adherence indicates significant need for commissioners and service providers to improve service transition experiences.Declaration of interestNone. PMID: 31159893 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 5, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Evolutionary biology: an essential basic science for the training of the next generation of psychiatrists.
Authors: Abed R, Ayton A, St John-Smith P, Swanepoel A, Tracy DK Abstract SummaryEvolutionary science can serve as the high-level organising principle for understanding psychiatry. Evolutionary concepts generate new models and ideas for future psychiatric study, research, policy and therapy. The authors accordingly make the case for the inclusion of evolutionary biology in the postgraduate education of psychiatric trainees.Declaration of interestNone. PMID: 31162000 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 5, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Why we need to take personality disorder out of the doghouse.
Authors: Tyrer P Abstract SummaryThe diagnosis of personality disorder is sometimes tolerated but often reviled as a label to attach to people we do not like. This is hardly surprising when we consider that problems in interpersonal relationships constitute the main feature of the disorder. But we cannot escape the fact that personality problems are extremely common and rejection on grounds of perceived undesirability is doltish. Both the DSM-5 (2013) alternative model and new ICD-11 classification of personality may help understanding as they are more in tune with science. Most of the previous classifications have...
Source: The British Journal of Psychiatry for Mental Science - June 4, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The mental health professional at the feet of the Ebola virus: individual treatment and global mental challenges.
Authors: Cénat JM, Balayulu-Makila O, Derivois D, Felix N, Mukunzi JN, Bukaka J, Birangui JP, Rousseau C Abstract SummaryMental health professionals form an important component of the response teams currently working in the Democratic Republic of the Congo to treat what is historically the second-largest Ebola outbreak. They provide psychological treatment to patients under extraordinary conditions, helping them cope with anxiety and the daily death of other patients.Declaration of interestNone. PMID: 31142389 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - June 1, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Self-harm in midlife: analysis using data from the Multicentre Study of Self-harm in England.
CONCLUSION: Self-harm in midlife represents a key target for intervention. Addressing underlying issues, alcohol use and economic factors may help prevent further self-harm and suicide.Declaration of interestK.H. and N.K. are members of the Department of Health's National Suicide Prevention Advisory Group. N.K. chaired the National Institute for Health and Care Excellence (NICE) guideline development group for the longer-term management of self-harm and the NICE Topic Expert Group which developed the quality standards for self-harm services. N.K. also chairs the NICE guideline committee for the management of depression. Al...
Source: The British Journal of Psychiatry for Mental Science - June 1, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The Dobson-Rawlins pact and the National Institute for Health and Care Excellence: impact of political independence on scientific and legal accountability.
Authors: McPherson S, Sunkin M Abstract This analysis considers whether the independence of the National Institute for Health and Care Excellence (NICE), while safeguarding guidelines from commercial lobbying, may render NICE legally and scientifically unaccountable. The analysis examines the role of judicial reviews and stakeholder consultations in place of peer review in light of current debates concerning the depression guideline.Declaration of interestNone. PMID: 31138337 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 30, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Brief cognitive-behavioural therapy for patients in the community with schizophrenia: Randomised controlled trial in Beijing, China - RETRACTION.
Authors: Guo ZH, Li ZJ, Ma Y, Sun J, Guo JH, Li WX, Wang ZQ, Xu HL, Ng RMK, Turkington D, Kingdon D PMID: 31111798 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 23, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Ensuring research integrity: setting standards for robust and ethical conduct and reporting of research.
We present an account of why we decided to retract a paper. We discovered a lack of adherence to conventional trials registration, execution, interpretation and reporting, and consequently, with the authors, needed to correct the scientific record. We set out our responses in general to strengthen research integrity.Declaration of interestK.S.B. is Editor-in-Chief of the British Journal of Psychiatry. W.L., K.R.K. and S.M.L. are members of the senior editorial committee and the research integrity committee for the journal. In the past three years, S.M.L. has received research support from Janssen and Lundbeck, and personal...
Source: The British Journal of Psychiatry for Mental Science - May 23, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Anorexia nervosa: 30-year outcome.
CONCLUSIONS: This long-term follow-up study reflects the course of adolescent-onset anorexia nervosa and has shown a favourable outcome regarding mortality and full symptom recovery. However, one in five had a chronic eating disorder.Declaration of interestNone. PMID: 31113504 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 23, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Long-term effects of prenatal exposure to earthquake on adult schizophrenia.
CONCLUSIONS: Prenatal (particularly early pregnancy) exposure to maternal stress after a major disaster substantially affects the mental health of Chinese adults.Declaration of interestNone. PMID: 31113505 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 23, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Uncovering neurodevelopmental features in bipolar affective disorder.
Authors: Valli I, Fabbri C, Young AH Abstract SummarySchizophrenia and bipolar disorder are genetically related and their clinical features overlap. Schizophrenia is conceptualised as a neurodevelopmental disorder but the evidence for bipolar disorder is less clear. Cluster-analytic approaches reveal different cognitive profiles within bipolar disorder, possibly reflective of differing neurodevelopmental loads, which are also suggested by recent genetic and neuroimaging studies. Such studies suggest the potential utility of further clinical subcategories in bipolar disorder based on neurodevelopmental load.Declarat...
Source: The British Journal of Psychiatry for Mental Science - May 23, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Urbanicity and risk of first-episode psychosis: incidence study in Brazil.
Authors: Del-Ben CM, Shuhama R, Loureiro CM, Ragazzi TCC, Zanatta DP, Tenan SHG, Ferreira Santos JL, Louzada-Junior P, Dos Santos AC, Morgan C, Menezes PR Abstract We estimated the incidence of first-episode psychosis over a 3-year period in a Brazilian catchment area comprising the region's main city, Ribeirão Preto (1 425 306 persons-years at risk), and 25 other municipalities with a total of 1 646 556 persons-years at risk. The incidence rates were estimated and adjusted by gender and age, using the direct standardisation method to the world population as reference. The incidence of psychosis was higher i...
Source: The British Journal of Psychiatry for Mental Science - May 19, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Childhood adversity and adolescent psychopathology: evidence for mediation in a national longitudinal cohort study.
CONCLUSIONS: Parent-child conflict explains almost half the relationship between childhood adversity and persisting externalising problems in adolescence, and a fifth of the relationship with persisting internalising problems. This suggests parent-child conflict is a good target for interventions in childhood to prevent adolescent psychopathology.Declaration of interestNone. PMID: 31094302 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 18, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Eighteen-year trajectories of depressive symptoms in mothers with a lifetime eating disorder: findings from the ALSPAC cohort.
CONCLUSIONS: Women with eating disorders experience persistently greater depressive symptoms across the life-course. More training for practitioners and midwives on how to recognise eating disorders in pregnancy could help to identify depressive symptoms and reduce the long-term burden of disease resulting from this comorbidity.Declaration of interestNone. PMID: 31084625 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 16, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The case for removing intellectual disability and autism from the Mental Health Act - ERRATUM.
Authors: Hollins S, Lodge KM, Lomax P PMID: 31084631 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 16, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Surface-based shared and distinct resting functional connectivity in attention-deficit hyperactivity disorder and autism spectrum disorder.
CONCLUSIONS: Our results may shed new light on the underlying mechanisms of ASD and ADHD and facilitate the development of new diagnostic methods for these disorders.Declaration of interestJ.K. holds equity in a startup company, MNT. PMID: 31088591 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 16, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The neuroscience of attachment: implications for psychological therapies.
Authors: Holmes J, Slade A Abstract SummaryRecent advances in attachment-informed relational neuroscience point to possible mechanisms of action of psychological therapies, with implications for effective practice.Declaration of interestNone. PMID: 31088592 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 16, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Kaleidoscope.
Authors: Tracy DK, Joyce DW, Shergill SS PMID: 31088593 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 16, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Prison healthcare services: the need for political courage.
Authors: Piper M, Forrester A, Shaw J Abstract SummaryPrisons in England and Wales have reached a low point in service delivery. Despite initial improvements after National Health Service transfer in 2006, it has deteriorated since 2010, with numerous reports giving cause for concern. Improvements are now urgently required, and political courage and a revised national programme of expenditure are necessary.Declaration of interestNone. PMID: 31068228 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 10, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Neighbourhood characteristics and prevalence and severity of depression: pooled analysis of eight Dutch cohort studies.
CONCLUSIONS: This large-scale pooled analysis across eight Dutch cohort studies shows that urbanisation and various socioeconomic, physical and social neighbourhood characteristics are associated with depression, indicating that a wide range of environmental aspects may relate to poor mental health.Declaration of interestNone. PMID: 31057126 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 8, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Predictors of moving on from mental health supported accommodation in England: national cohort study.
CONCLUSIONS: Most people do not move on from supported accommodation within the expected time frame. Greater focus on human rights and recovery-based practice may increase service effectiveness.Declaration of interestH.K., S.P., M.K., S.E., P. McCrone, M.A., S.C., G.L. and G.S. report a grant from National Institute of Health Research during the conduct of the study. All other authors report having no conflicts to disclose. PMID: 31046864 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - May 5, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Are neuropsychiatric symptoms modifiable risk factors for cognitive decline in Alzheimer's disease and vascular dementia?
Authors: Savulich G, O'Brien JT, Sahakian BJ Abstract SummaryAlzheimer's disease and vascular dementia are associated with overlapping symptoms of anxiety and depression. More accurate discrimination between emerging neuropsychiatric and cognitive symptoms would better assist illness detection. The potential for protection against cognitive decline and dementia following early identification and intervention of neuropsychiatric symptoms warrants investigation.Declaration of interestB.J.S. consults for Peak, Mundipharma and Cambridge Cognition. J.T.O. has acted as a consultant for TauRx, Axon, GE Healthcare and Lill...
Source: The British Journal of Psychiatry for Mental Science - May 2, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Off-label use of ketamine for treatment-resistant depression in clinical practice: European perspective.
Authors: López-Díaz Á, Murillo-Izquierdo M, Moreno-Mellado E Abstract SummaryKetamine therapy for treatment-resistant depression in European national health systems may only be considered after attempting all evidence-based antidepressant strategies outlined in clinical guidelines. This paper seeks to explain the ethical, regulatory and procedural framework for the off-label use of ketamine for treatment-resistant depression within a public healthcare system.Declaration of interestNone. PMID: 31030677 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 30, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Collaborative care: enough of the why; what about the how?
Authors: Ramanuj PP, Pincus HA Abstract The clinical and cost-effectiveness of collaborative care for improving outcomes in people with mental and physical comorbidities is well established. However, translating these models into enduring change in routine care has proved difficult. In this editorial we outline how to shift the conversation on collaborative care from 'what are we supposed to do?' to 'how we can do this'.Declaration of interestP.P.R. has received honoraria from Publicis LifeBrands and the Institute for Healthcare Improvement outside of the submitted work. H.A.P. reports personal fees from the BIND H...
Source: The British Journal of Psychiatry for Mental Science - April 28, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The promise of two-person neuroscience for developmental psychiatry: using interaction-based sociometrics to identify disorders of social interaction.
Authors: Leong V, Schilbach L Abstract SummarySocial interactions are fundamental for human development, and disordered social interactions are pervasive in many psychiatric disorders. Recent advances in 'two-person neuroscience' have provided new tools for characterising social interactions. Accordingly, interaction-based 'sociometrics' hold great promise for developmental psychology and psychiatry, particularly in the early identification of social disorders.Declaration of interestNone. PMID: 31014406 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 26, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The case for removing intellectual disability and autism from the Mental Health Act.
Authors: Hollins S, Lodge KM, Lomax P Abstract SummaryIntellectual disability (also known as learning disability in UK health services) and autism are distinct from the serious mental illnesses for which the Mental Health Act is designed to be used. Their inclusion in the definition of mental disorder is discriminatory, resulting in unjust deprivations of liberty. Intellectual disability and autism should be excluded from the Mental Health Act.Declaration of interestNone. PMID: 31014411 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 26, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Commentary on … the overlapping and distinct resting functional connectivity between autism spectrum disorder and attention-deficit hyperactivity disorder.
Commentary on… the overlapping and distinct resting functional connectivity between autism spectrum disorder and attention-deficit hyperactivity disorder. Br J Psychiatry. 2019 Apr 24;:1-2 Authors: Mehra C, Absoud M Abstract SummaryAltered neural connectivity in neurodevelopmental disorders is likely subtle, meaning that neuroimaging literature studying development has produced heterogeneous findings. A recent study, published in this issue, illustrates the translational potential of functional connectivity magnetic resonance imaging findings as a biomarker for attention-deficit hyperactivity di...
Source: The British Journal of Psychiatry for Mental Science - April 26, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Repetitive transcranial magnetic stimulation in non-treatment-resistant depression.
Authors: Kiebs M, Hurlemann R, Mutz J Abstract SummaryRepetitive transcranial magnetic stimulation (rTMS) has been investigated as treatment for major depressive episodes since the early 1990s. Using data from a recent meta-analysis, we show that most patients included in randomised trials display relatively high degrees of treatment resistance. This might have unfavourably biased the clinical reputation of rTMS.Declaration of interestsM.K. has received a lecture fee from Innomed Medizintechnik in 2017 and 2018. PMID: 31014413 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 26, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Continuity of care and clinical outcomes in the community for people with severe mental illness.
CONCLUSIONS: There is evidence of declining continuity of care in this 11-year study of people with schizophrenia, and of an independent effect of this on worse clinical outcomes. We suggest that this is related to reorganisation of services.Declaration of interestNone. PMID: 31012407 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 25, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

#BJPsych and social media - likes, followers and leading?
This article explores the growing interface between social media and academic publishing. We discuss how the British Journal of Psychiatry (BJPsych) and other scientific journals are engaging with social media to communicate in a digital world. A growing body of evidence suggests that public visibility and constructive conversation on social media networks can be beneficial for researchers and clinicians, influencing research in a number of key ways. This engagement presents new opportunities for more widely disseminating information, but also carries risks. We note future prospects and ask where BJPsych should strategical...
Source: The British Journal of Psychiatry for Mental Science - April 25, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research