Response to the article 'The role of prenatal stress as a pathway to personality disorder: longitudinal birth cohort study'.
Authors: Brown G, Ginestet CE PMID: 33250062 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - December 1, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Kaleidoscope.
Authors: Tracy DK, Joyce DW, Albertson DN, Shergill SS PMID: 33250063 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - December 1, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Authors' reply.
Authors: Brannigan R, Clarke M PMID: 33250064 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - December 1, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Re: 'The role of prenatal stress as a pathway to personality disorder'.
Authors: Tavares A, McAlpine L PMID: 33250065 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - December 1, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Mental health services in the wake of COVID-19 and opportunities for change.
Authors: Arnone D PMID: 33250066 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - December 1, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Author's reply.
Authors: Kelly BD PMID: 33250067 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - December 1, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Gender equality in academic publishing: action from the BJPsych.
Authors: Upthegrove R, de Cates A, Shuttleworth A, Tracy DK, Broome MR, Lingford-Hughes A Abstract Women in academic publishing and academic psychiatry face many challenges of gender inequality, including significant pay differentials, poor visibility in senior positions and a male-dominated hierarchical system. We discuss this problem and outline how the BJPsych plans to tackle these issues it in its own publishing. PMID: 33234181 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - November 27, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Mental health before and during COVID-19 in two longitudinal UK population cohorts.
Authors: Kwong ASF, Pearson RM, Adams MJ, Northstone K, Tilling K, Smith D, Fawns-Ritchie C, Bould H, Warne N, Zammit S, Gunnell D, Moran P, Micali N, Reichenberg A, Hickman M, Rai D, Haworth S, Campbell A, Altschul D, Flaig R, McIntosh AM, Lawlor DA, Porteous D, Timpson NJ PMID: 33228822 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - November 25, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Psychological interventions as an alternative and add-on to antidepressant medication to prevent depressive relapse: systematic review and meta-analysis.
CONCLUSIONS: This study found no evidence to suggest that adding a psychological intervention to tapering increases the risk of relapse when compared with antidepressants alone. Adding a psychological intervention to antidepressant use reduces relapse risk significantly versus antidepressants alone. As neither strategy is routinely implemented these findings are relevant for patients, clinicians and guideline developers. PMID: 33205715 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - November 21, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Psychological interventions for depression in children and young people with an intellectual disability and/or autism: systematic review.
CONCLUSIONS: Well-designed, randomised controlled trials are critical to develop an evidence base for psychological treatment for young people with intellectual disability and/or autism with depression. Future research should evaluate the treatment experiences of young people, their families and therapists. PMID: 33198825 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - November 18, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Clinical utility of the parent-reported Strengths and Difficulties Questionnaire as a screen for emotional and behavioural difficulties in children and adolescents with intellectual disability.
Authors: Murray CA, Hastings RP, Totsika V Abstract We assessed the clinical utility of the parent-reported Strengths and Difficulties Questionnaire (SDQ) as a screen for emotional and behavioural difficulties in 626 children and young people with intellectual disability. Using the Developmental Behavior Checklist (DBC2-P) to determine clinical caseness, the area under the curve for the SDQ total difficulties score was 0.876 (95% CI 0.841-0.911), indicating that it is a good measure for identifying significant emotional and behavioural difficulties requiring further investigation. Analyses supported the use of the ...
Source: The British Journal of Psychiatry for Mental Science - November 18, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Efficacy of the Zero Suicide framework in reducing recurrent suicide attempts: cross-sectional and time-to-recurrent-event analyses.
CONCLUSIONS: This paper demonstrates a reduction in repeated suicide attempts after an index attempt and a longer time to a subsequent attempt for those receiving multilevel care based on the Zero Suicide framework. PMID: 33176895 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - November 14, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Towards safer risperidone prescribing in Alzheimer's disease.
Authors: Reeves S, Bertrand J, Uchida H, Yoshida K, Otani Y, Ozer M, Liu KY, Bramon E, Bies R, Pollock BG, Howard R Abstract BACKGROUND: In the treatment of psychosis, agitation and aggression in Alzheimer's disease, guidelines emphasise the need to 'use the lowest possible dose' of antipsychotic drugs, but provide no information on optimal dosing. AIMS: This analysis investigated the pharmacokinetic profiles of risperidone and 9-hydroxy (OH)-risperidone, and how these related to treatment-emergent extrapyramidal side-effects (EPS), using data from The Clinical Antipsychotic Trials of Intervention Effectiveness...
Source: The British Journal of Psychiatry for Mental Science - November 14, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Umbrella systematic review of systematic reviews and meta-analyses on comorbid physical conditions in people with autism spectrum disorder.
CONCLUSIONS: Comorbid physical conditions occur more commonly in people with ASD, but the evidence base is slim and more research is needed. Some comorbidities compound care if clinicians are unaware, for example sensory impairments, given the communication needs of people with ASD. Others, such as obesity, can lead to an array of other conditions, disadvantages and early mortality. It is essential that potentially modifiable physical conditions are identified to ensure people with ASD achieve their best outcomes. Heightening clinicians' awareness is important to aid in assessments and differential diagnoses, and to improv...
Source: The British Journal of Psychiatry for Mental Science - November 11, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Media guidelines for the responsible reporting and depicting of non-suicidal self-injury.
Authors: Westers NJ, Lewis SP, Whitlock J, Schatten HT, Ammerman B, Andover MS, Lloyd-Richardson EE Abstract Media coverage of non-suicidal self-injury (NSSI) ranges from providing helpful education to displaying graphic images. We offer the first research-informed, consensus-based guidelines for the responsible reporting and depicting of NSSI in the media, while also advising on ideas for dissemination and collaboration between media professionals and healthcare experts. PMID: 33161923 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - November 11, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Looking across health and healthcare outcomes for people with intellectual and developmental disabilities and psychiatric disorders: population-based longitudinal study.
CONCLUSIONS: Poorer outcomes for adults with IDD, particularly those with MHA, suggest a need for a comprehensive, system-wide approach spanning health, disability and social support. PMID: 33161927 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - November 11, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Disambiguation of psychotherapy: a search for meaning.
Authors: Castelpietra G, Simon J, Gutiérrez-Colosía MR, Rosenberg S, Salvador-Carulla L Abstract This analysis identifies the significant problem of ambiguity, variation and vagueness in relation to the intervention described as 'psychotherapy'. Its purpose is to raise international awareness of this problem and alternative solutions. PMID: 33143767 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - November 5, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Excess mortality associated with eating disorders: population-based cohort study.
CONCLUSIONS: Patients with eating disorders diagnosed in hospital settings experience five to seven times higher mortality rates compared with the overall population. There is an urgent need to understand the mortality risk factors to improve health outcomes among individuals with eating disorders. PMID: 33118892 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 31, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Comment on 'The vulnerability paradox in global mental health and its applicability to suicide'.
Authors: Adebisi A PMID: 33100239 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 28, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

'1 in 4' prevalence for psychiatric disorder …or should that really be '1 in 3'? Parity of esteem in statistical headlines.
'1 in 4' prevalence for psychiatric disorder…or should that really be '1 in 3'? Parity of esteem in statistical headlines. Br J Psychiatry. 2020 Nov;217(5):652 Authors: Moore A PMID: 33100240 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 28, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Further evidence for a role for the locus coeruleus in the aetiopathogenesis of dementia.
Authors: Mukaetova-Ladinska EB, Steinert J, Maltby J, Kronenberg G PMID: 33100241 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 28, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Kaleidoscope.
Authors: Tracy DK, Joyce DW, Albertson DN, Shergill SS PMID: 33100242 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 28, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Author's reply.
Authors: Curtis D PMID: 33100243 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 28, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Sarcosine in the management of schizophrenia.
Authors: Brennan D PMID: 33100244 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 28, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Impaired inhibitory processing: a new therapeutic target for autism and psychosis?
Authors: Heinze K, Barron HC, Howes EK, Ramaswami M, Broome MR Abstract In the healthy brain, homeostatic balance between excitation and inhibition maintains neural stability. Reduced inhibition may explain shared symptoms observed in autism and psychosis. Here we review evidence suggesting that altered levels of gamma-aminobutyric acid (GABA) may underlie both disorders, providing a potential cross-diagnostic therapeutic target. PMID: 33092656 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 25, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Paramedics in pandemics: protecting the mental wellness of those behind enemy lines.
Authors: Awais SB, Martins RS, Khan MS Abstract Besides a global health crisis, the COVID-19 pandemic has potential to have a severe and long-lasting psychological impact on frontline healthcare workers such as paramedics. It is imperative to shed light on these mental health issues and employ interventions to protect the mental wellness of this vulnerable group of healthcare workers. PMID: 33092658 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 25, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Mental health and wellbeing during the COVID-19 pandemic: longitudinal analyses of adults in the UK COVID-19 Mental Health & Wellbeing study.
Mental health and wellbeing during the COVID-19 pandemic: longitudinal analyses of adults in the UK COVID-19 Mental Health & Wellbeing study. Br J Psychiatry. 2020 Oct 21;:1-17 Authors: O'Connor RC, Wetherall K, Cleare S, McClelland H, Melson AJ, Niedzwiedz CL, O'Carroll RE, O'Connor DB, Platt S, Scowcroft E, Watson B, Zortea T, Ferguson E, Robb KA PMID: 33081860 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 22, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Benzodiazepines: it's time to return to the evidence.
Authors: Silberman E, Balon R, Starcevic V, Shader R, Cosci F, Fava GA, Nardi AE, Salzman C, Sonino N Abstract SUMMARY: We propose that discussions of benzodiazepines in the current psychiatric literature have become negatively biased and have strayed from the scientific evidence base. We advocate returning to the evidence in discussing benzodiazepines and adhering to clear definitions and conceptual rigour in commentary about them. PMID: 33040746 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 14, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Dissociative identity disorder: out of the shadows at last?
Authors: Reinders AATS, Veltman DJ Abstract Dissociative identity disorder (DID) is a severely debilitating disorder. Despite recognition in the current and past versions of the DSM, DID remains a controversial psychiatric disorder, which hampers its diagnosis and treatment. Neurobiological evidence regarding the aetiology of DID supports clinical observations that it is a severe form of post-traumatic stress disorder. PMID: 33023686 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 9, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Green care in psychiatry.
Authors: Cuthbert S, Kellas A, Page LA Abstract Engagement with natural environments is associated with improved health and well-being in the general population. This has implications for mental healthcare. Implementation of targeted nature-based interventions (green care) meets recovery needs and would enable research to develop, clarifying what works best for whom. PMID: 33028436 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 9, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Educational attainment trajectories among children and adolescents with depression, and the role of sociodemographic characteristics: longitudinal data-linkage study.
CONCLUSIONS: Those who receive a depression diagnosis during their school career show a drop in attainment in Year 11. Although this pattern was seen among multiple sociodemographic groups, gender, ethnicity and socioeconomic status predict more vulnerable subgroups within this clinical population who might benefit from additional educational support or more intensive treatment. PMID: 33028438 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 9, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Long-term outcomes of females with attention-deficit hyperactivity disorder: increased risk for self-harm.
We present data on predictors and mediators of such risk, highlighting a recent dual-process model involving trait impulsivity plus family- and peer-related contributors. We conclude with recommendations for assessment and preventive intervention. PMID: 33019955 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 8, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

The co-occurrence of smoking and suicide.
This article is an invited commentary on a recent article by Harrison et al. investigating the purported causal link between smoking behaviours and suicide attempts. PMID: 32998784 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 3, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Is mindfulness for psychosis harmful? Deconstructing a myth.
Authors: Böge K, Thomas N, Jacobsen P Abstract Mindfulness-based therapies are increasingly available for a range of mental disorders, such as depression and anxiety. However, there remain concerns that mindfulness has the potential to exacerbate psychosis, despite a growing body of literature demonstrating effectiveness. These concerns may relate to long-standing perceptions about the suitability of offering psychological therapies to people with psychosis. PMID: 32998787 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 3, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Kaleidoscope.
Authors: Tracy DK, Joyce DW, Albertson DN, Shergill SS PMID: 32981535 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - September 30, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Post-traumatic stress disorder as a risk factor for dementia: systematic review and meta-analysis.
Authors: Günak MM, Billings J, Carratu E, Marchant NL, Favarato G, Orgeta V Abstract BACKGROUND: Post-traumatic stress disorder (PTSD) has been identified as a potential risk factor for developing dementia. There are currently, however, no meta-analyses quantifying this risk. AIMS: To systematically review and quantify the risk of future dementia associated with PTSD across populations. PROSPERO registration number CRD42019130392. METHOD: We searched nine electronic databases up to 25 October 2019 for longitudinal studies assessing PTSD and risk of dementia. We used random- and fixed-effects meta-analy...
Source: The British Journal of Psychiatry for Mental Science - September 18, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Delusional content at initial presentation to a catchment-based early intervention service for psychosis.
CONCLUSIONS: This community sample offers a rare clinical lens into the severity and content of delusions in FEP. Although delusional severity was consistent across certain sociodemographic and clinical variables, this was not always the case. Future research should now consider the course of delusion themes over time. PMID: 32900414 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - September 10, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Overlap between attention-deficit hyperactivity disorder and neurodevelopmental, externalising and internalising disorders: separating unique from general psychopathology effects.
CONCLUSIONS: Findings suggest that ADHD comorbidity is largely explained by genetically influenced general psychopathology, but the strong link between ADHD and other neurodevelopmental disorders is also substantially driven by unique genetic influences. PMID: 32892757 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - September 9, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Imagery rescripting and eye movement desensitisation and reprocessing as treatment for adults with post-traumatic stress disorder from childhood trauma: randomised clinical trial.
CONCLUSIONS: ImRs and EMDR treatments were found to be effective in treating PTSD symptoms arising from childhood trauma, and in reducing other symptoms such as depression, dissociation and trauma-related cognitions. The low drop-out rates suggest that the treatments were well tolerated by participants. The results from this study provide evidence for the use of trauma-focused treatments for Ch-PTSD. PMID: 32892758 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - September 9, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Emotional abuse and neglect: time to focus on prevention and mental health consequences.
Authors: Kumari V Abstract Emotional abuse and emotional neglect are among the most prevalent of childhood maltreatment types and associated with a range of poor mental health outcomes. We need to move beyond correlational research and shift our focus to sophisticated multimodal studies to fully understand the psychobiological mechanisms underlying these associations and to intervention studies. PMID: 32892766 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - September 9, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Trends in generalised anxiety disorders and symptoms in primary care: UK population-based cohort study.
CONCLUSIONS: We observed a substantial increase in general practitioner consulting for generalised anxiety and depression recently, concentrated within younger people and in particular women. PMID: 32895062 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - September 9, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Kaleidoscope.
Authors: Tracy DK, Joyce DW, Albertson DN, Shergill SS PMID: 32854811 [PubMed - in process] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - August 30, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Efficacy of interventions to reduce coercive treatment in mental health services: umbrella review of randomised evidence.
CONCLUSIONS: Different levels of evidence indicate the benefit of staff training, shared decision-making interventions and integrated care interventions to reduce coercive treatment in mental health services. These different levels of evidence should be considered in the development of policy, clinical and implementation initiatives to reduce coercive practices in mental healthcare, and should lead to further studies in both high- and low-income countries to improve the strength and credibility of the evidence base. PMID: 32847633 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - August 29, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Structural brain abnormalities in schizophrenia in adverse environments: examining the effect of poverty and violence in six Latin American cities.
CONCLUSIONS: Our results highlight the interplay between environment, particularly poverty, and individual characteristics in psychosis. This is particularly important for harsh environments such as low- and middle-income countries, where potentially less brain vulnerability (less grey matter loss) is sufficient to become unwell in adverse (poor) environments. PMID: 32807243 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - August 20, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Effects of genomic copy number variants penetrant for schizophrenia on cortical thickness and surface area in healthy individuals: analysis of the UK Biobank.
Authors: Caseras X, Kirov G, Kendall KM, Rees E, Legge SE, Bracher-Smith M, Escott-Price V, Murphy K Abstract BACKGROUND: Schizophrenia is a highly heritable disorder with undetermined neurobiological causes. Understanding the impact on brain anatomy of carrying genetic risk for the disorder will contribute to uncovering its neurobiological underpinnings. AIMS: To examine the effect of rare copy number variants (CNVs) associated with schizophrenia on brain cortical anatomy in a sample of unaffected participants from the UK Biobank. METHOD: We used regression analyses to compare cortical thickness and surfac...
Source: The British Journal of Psychiatry for Mental Science - August 16, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Threat, hostility and violence in childhood and later psychotic disorder: population-based case-control study.
CONCLUSIONS: Our findings extend previous research on childhood adversity and suggest a degree of specificity for severe adversities involving threat, hostility and violence. PMID: 32778182 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - August 13, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Unravelling the mental health productivity puzzle: where do we start?
Authors: Maddison P, Castelli A, Tiffin PA Abstract In this editorial we define 'productivity' and 'efficiency' in a mental health service context, outlining the key challenges to measuring these in practice. We attempt to bring clarity of thought to this often debated, but rarely researched area. PMID: 32778201 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - August 13, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Cultural research deconstructs the psychosocial construct 'expressed emotion'.
Authors: Heru AM Abstract Expressed emotion (EE) is a highly researched psychosocial construct. Cultural research challenges the assumption that high family criticism is a universal determinant of poor outcome, especially for chronic illness. The concept of warmth, an original component of EE, was dropped owing to the complexity of its measurement. Warmth has now been resurrected as an important predictor of good patient outcome. Cultural scrutiny and appropriate adaptation of any psychosocial construct is necessary before its acceptance into the medical lexicon of healthcare. PMID: 32778202 [PubMed - as suppli...
Source: The British Journal of Psychiatry for Mental Science - August 13, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Contacts with primary and secondary healthcare prior to suicide: case-control whole-population-based study using person-level linked routine data in Wales, UK, 2000-2017.
CONCLUSIONS: Help-seeking occurs in those at risk of suicide and escalates in the weeks before their death. There is an opportunity to identify and intervene through these contacts. PMID: 32744207 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - August 4, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Cost-effectiveness of WHO Problem Management Plus for adults with mood and anxiety disorders in a post-conflict area of Pakistan: randomised controlled trial.
CONCLUSIONS: The PM+ intervention was more effective but also more costly than EUC in reducing symptoms of anxiety, depression and improving functioning in adults impaired by psychological distress in a post-conflict setting of Pakistan. PMID: 32720628 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - July 30, 2020 Category: Psychiatry Tags: Br J Psychiatry Source Type: research