Towards precision in the diagnostic profiling of patients: leveraging symptom dynamics as a clinical characterisation dimension in the assessment of major depressive disorder
CONCLUSIONS: The majority of participants within the same depressive symptom severity group displayed differential symptom dynamics. Examining symptom dynamics provides information about person-specific psychopathological expression beyond severity levels by revealing how symptoms aggravate each other over time. These results suggest that symptom dynamics may be a promising new dimension for clinical characterisation, warranting replication in independent samples. To inform personalised treatment planning, a next step concerns linking different symptom relationship patterns to treatment response and clinical course, includ...
Source: The British Journal of Psychiatry for Mental Science - April 8, 2024 Category: Psychiatry Authors: Omid V Ebrahimi Denny Borsboom Ria H A Hoekstra Sacha Epskamp Edoardo G Ostinelli Jojanneke A Bastiaansen Andrea Cipriani Source Type: research

Associations between multimorbidity and neuropathology in dementia: consideration of functional cognitive disorders, psychiatric illness and dementia mimics
CONCLUSIONS: Physical multimorbidity alone is not associated with greater dementia-related neuropathological change; inappropriate inclusion of brain-related conditions in multimorbidity measures and misdiagnosis of neurodegenerative dementia may better explain increased rates of clinical dementia in multimorbidity.PMID:38584319 | DOI:10.1192/bjp.2024.25 (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 8, 2024 Category: Psychiatry Authors: Calum A Hamilton Fiona E Matthews Johannes Attems Paul C Donaghy Daniel Erskine John-Paul Taylor Alan J Thomas Source Type: research

Towards precision in the diagnostic profiling of patients: leveraging symptom dynamics as a clinical characterisation dimension in the assessment of major depressive disorder
CONCLUSIONS: The majority of participants within the same depressive symptom severity group displayed differential symptom dynamics. Examining symptom dynamics provides information about person-specific psychopathological expression beyond severity levels by revealing how symptoms aggravate each other over time. These results suggest that symptom dynamics may be a promising new dimension for clinical characterisation, warranting replication in independent samples. To inform personalised treatment planning, a next step concerns linking different symptom relationship patterns to treatment response and clinical course, includ...
Source: The British Journal of Psychiatry for Mental Science - April 8, 2024 Category: Psychiatry Authors: Omid V Ebrahimi Denny Borsboom Ria H A Hoekstra Sacha Epskamp Edoardo G Ostinelli Jojanneke A Bastiaansen Andrea Cipriani Source Type: research

Associations between multimorbidity and neuropathology in dementia: consideration of functional cognitive disorders, psychiatric illness and dementia mimics
CONCLUSIONS: Physical multimorbidity alone is not associated with greater dementia-related neuropathological change; inappropriate inclusion of brain-related conditions in multimorbidity measures and misdiagnosis of neurodegenerative dementia may better explain increased rates of clinical dementia in multimorbidity.PMID:38584319 | DOI:10.1192/bjp.2024.25 (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 8, 2024 Category: Psychiatry Authors: Calum A Hamilton Fiona E Matthews Johannes Attems Paul C Donaghy Daniel Erskine John-Paul Taylor Alan J Thomas Source Type: research

Towards precision in the diagnostic profiling of patients: leveraging symptom dynamics as a clinical characterisation dimension in the assessment of major depressive disorder
CONCLUSIONS: The majority of participants within the same depressive symptom severity group displayed differential symptom dynamics. Examining symptom dynamics provides information about person-specific psychopathological expression beyond severity levels by revealing how symptoms aggravate each other over time. These results suggest that symptom dynamics may be a promising new dimension for clinical characterisation, warranting replication in independent samples. To inform personalised treatment planning, a next step concerns linking different symptom relationship patterns to treatment response and clinical course, includ...
Source: The British Journal of Psychiatry for Mental Science - April 8, 2024 Category: Psychiatry Authors: Omid V Ebrahimi Denny Borsboom Ria H A Hoekstra Sacha Epskamp Edoardo G Ostinelli Jojanneke A Bastiaansen Andrea Cipriani Source Type: research

The potential unintended consequences of Mental Health Act reforms in England and Wales on people with intellectual disability and/or autism: commentary, McKinnon et al
Br J Psychiatry. 2024 Apr 2:1-2. doi: 10.1192/bjp.2024.57. Online ahead of print.NO ABSTRACTPMID:38563223 | DOI:10.1192/bjp.2024.57 (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - April 2, 2024 Category: Psychiatry Authors: Iain McKinnon Patrick Keown Source Type: research

The effect of flexible cognitive-behavioural therapy and medical treatment, including antidepressants on post-traumatic stress disorder and depression in traumatised refugees: pragmatic randomised controlled clinical trial - CORRIGENDUM
Br J Psychiatry. 2024 Mar 18:1. doi: 10.1192/bjp.2024.66. Online ahead of print.NO ABSTRACTPMID:38494743 | DOI:10.1192/bjp.2024.66 (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - March 18, 2024 Category: Psychiatry Authors: Caecilie B öck Buhmann Merete Nordentoft Morten Ekstroem Jessica Carlsson Erik Lykke Mortensen Source Type: research

Neurocognitive skills and vulnerability for psychosis in depression and across the psychotic spectrum: findings from the PRONIA Consortium - CORRIGENDUM
Br J Psychiatry. 2024 Mar 18:1. doi: 10.1192/bjp.2024.43. Online ahead of print.NO ABSTRACTPMID:38497099 | DOI:10.1192/bjp.2024.43 (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - March 18, 2024 Category: Psychiatry Authors: Carolina Bonivento Lana Kambeitz-Ilankovic Eleonora Maggioni Stefan Borgwardt Rebekka Lencer Eva Meisenzahl Joseph Kambeitz Stephan Ruhrmann Raimo K R Salokangas Alessandro Bertolino Alexandra Stainton Julian Wenzel Christos Pantelis Stephen J Wood Rachel Source Type: research

The effect of flexible cognitive-behavioural therapy and medical treatment, including antidepressants on post-traumatic stress disorder and depression in traumatised refugees: pragmatic randomised controlled clinical trial - CORRIGENDUM
Br J Psychiatry. 2024 Mar 18:1. doi: 10.1192/bjp.2024.66. Online ahead of print.NO ABSTRACTPMID:38494743 | DOI:10.1192/bjp.2024.66 (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - March 18, 2024 Category: Psychiatry Authors: Caecilie B öck Buhmann Merete Nordentoft Morten Ekstroem Jessica Carlsson Erik Lykke Mortensen Source Type: research

Neurocognitive skills and vulnerability for psychosis in depression and across the psychotic spectrum: findings from the PRONIA Consortium - CORRIGENDUM
Br J Psychiatry. 2024 Mar 18:1. doi: 10.1192/bjp.2024.43. Online ahead of print.NO ABSTRACTPMID:38497099 | DOI:10.1192/bjp.2024.43 (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - March 18, 2024 Category: Psychiatry Authors: Carolina Bonivento Lana Kambeitz-Ilankovic Eleonora Maggioni Stefan Borgwardt Rebekka Lencer Eva Meisenzahl Joseph Kambeitz Stephan Ruhrmann Raimo K R Salokangas Alessandro Bertolino Alexandra Stainton Julian Wenzel Christos Pantelis Stephen J Wood Rachel Source Type: research