Quantifying the scale of erosion along major coastal aquifers of Pakistan using geospatial and machine learning approaches
This study aims to monitor erosion along the major coastal aquifers of Pakistan and propose an approach that combines data fusion into the machine and deep learning image segmentation architectures for the erosion and accretion assessment in seascapes. The analysis demonstrated the image segmentation U-Net with EfficientNet backbone achieved the highest F1 score of 0.93, while ResNet101 achieved the lowest F1 score of 0.77. Resultant erosion maps indicated that Sandspit experiencing erosion at 3.14 km2 area. Indus delta is showing erosion, approximately 143 km2 of land over the past 30 years. Sonmiani has undergone substan...
Source: Environmental Science and Pollution Research International - April 25, 2024 Category: Environmental Health Authors: Hafsa Aeman Hong Shu Hamera Aisha Imran Nadeem Rana Waqar Aslam Source Type: research
Mutational spectrum of CFTR in cystic fibrosis patients with gastrointestinal and hepatobiliary manifestations
CONCLUSION: The study reports novel and reported variants in the CFTR gene in CF patients in Pakistani population having distinct phenotypes. It also emphasizes screening suspected Pakistani CF patients for the p. (Met1Thr) variant because of its increased observance and prevalence in the study. Moreover, the findings also signify searching for additional pathogenic variants in the genome of CF patients, which may modify the phenotypes. The findings contribute valuable information for the diagnosis, genetic counseling, and potential therapeutic strategies for CF patients in Pakistan.PMID:38662334 | DOI:10.1007/s11033-024-0...
Source: Molecular Biology Reports - April 25, 2024 Category: Molecular Biology Authors: Nadia Waheed Rehmana Waris Maryam Naseer Ayesha Razzaq Nighat Haider Abid Ali Shah Asmat Ullah Source Type: research
Assessment of Genomic Diversity and Selective Pressures in Crossbred Dairy Cattle of Pakistan
This study aims to provide the first overview of the selective pressures on the genome of crossbred dairy cattle in Pakistan. A total of eighty-one crossbred, thirty-two HF and twenty-four Sahiwal cattle were genotyped, and additional SNP genotype data for HF and Sahiwal were collected from a public database to equate the sample size in each group. Within-breed selection signatures in crossbreds were investigated using the integrated haplotype score. Crossbreds were also compared to each of their parental breeds to discover between-population signatures of selection using two approaches: cross-population extended haplotype...
Source: Biochemical Genetics - April 25, 2024 Category: Genetics & Stem Cells Authors: Fakhar Un Nisa Rubab Zahra Naqvi Fazeela Arshad Iram Ilyas Muhammad Asif Imran Amin Raphael Mrode Shahid Mansoor Zahid Mukhtar Source Type: research
Quantifying the scale of erosion along major coastal aquifers of Pakistan using geospatial and machine learning approaches
This study aims to monitor erosion along the major coastal aquifers of Pakistan and propose an approach that combines data fusion into the machine and deep learning image segmentation architectures for the erosion and accretion assessment in seascapes. The analysis demonstrated the image segmentation U-Net with EfficientNet backbone achieved the highest F1 score of 0.93, while ResNet101 achieved the lowest F1 score of 0.77. Resultant erosion maps indicated that Sandspit experiencing erosion at 3.14 km2 area. Indus delta is showing erosion, approximately 143 km2 of land over the past 30 years. Sonmiani has undergone substan...
Source: Environmental Science and Pollution Research International - April 25, 2024 Category: Environmental Health Authors: Hafsa Aeman Hong Shu Hamera Aisha Imran Nadeem Rana Waqar Aslam Source Type: research
Mutational spectrum of CFTR in cystic fibrosis patients with gastrointestinal and hepatobiliary manifestations
CONCLUSION: The study reports novel and reported variants in the CFTR gene in CF patients in Pakistani population having distinct phenotypes. It also emphasizes screening suspected Pakistani CF patients for the p. (Met1Thr) variant because of its increased observance and prevalence in the study. Moreover, the findings also signify searching for additional pathogenic variants in the genome of CF patients, which may modify the phenotypes. The findings contribute valuable information for the diagnosis, genetic counseling, and potential therapeutic strategies for CF patients in Pakistan.PMID:38662334 | DOI:10.1007/s11033-024-0...
Source: Molecular Biology Reports - April 25, 2024 Category: Molecular Biology Authors: Nadia Waheed Rehmana Waris Maryam Naseer Ayesha Razzaq Nighat Haider Abid Ali Shah Asmat Ullah Source Type: research
Assessment of Genomic Diversity and Selective Pressures in Crossbred Dairy Cattle of Pakistan
This study aims to provide the first overview of the selective pressures on the genome of crossbred dairy cattle in Pakistan. A total of eighty-one crossbred, thirty-two HF and twenty-four Sahiwal cattle were genotyped, and additional SNP genotype data for HF and Sahiwal were collected from a public database to equate the sample size in each group. Within-breed selection signatures in crossbreds were investigated using the integrated haplotype score. Crossbreds were also compared to each of their parental breeds to discover between-population signatures of selection using two approaches: cross-population extended haplotype...
Source: Biochemical Genetics - April 25, 2024 Category: Genetics & Stem Cells Authors: Fakhar Un Nisa Rubab Zahra Naqvi Fazeela Arshad Iram Ilyas Muhammad Asif Imran Amin Raphael Mrode Shahid Mansoor Zahid Mukhtar Source Type: research
China set to fetch first rocks from mysterious far side of the Moon
There’s a giant hole on the backside of the Moon. The South Pole–Aitken (SPA) Basin, the Moon’s largest and oldest impact crater, is more than 2500 kilometers wide and 8 kilometers deep—nearly big enough to swallow two Indias and hide the Himalayas. Now, China plans to land in it.
The basin may have been blasted out during a barrage of asteroids that pummeled Earth and other inner Solar System bodies billions of years ago, and scientists have long wanted to get their hands on SPA rocks to test the idea. The China National Space Administration (CNSA) aims to provide them with the Chang’e-6 mission, which sci...
Source: Science of Aging Knowledge Environment - April 24, 2024 Category: Geriatrics Source Type: research
Environmental Surveillance of Poliovirus and Non-polio Enteroviruses in Iran, 2017 –2023: First Report of Imported Wild Poliovirus Type 1 Since 2000
AbstractIn Iran, which is at high risk of the Wild Poliovirus (WPV) and Vaccine-Derived Poliovirus (VDPV) importation due to its neighborhood with two polio endemic countries, Pakistan and Afghanistan, Environmental Surveillance (ES) was established in November 2017. Sistan-Balouchestan province was chosen for the ES due to its vicinity with Pakistan and Afghanistan. Five sewage collection sites in 4 cities (Zahedan, Zabol, Chabahar and Konarak) were selected in the high-risk areas. Since the establishment of ES in November 2017 till the end of 2023, 364 sewage specimens were collected and analyzed. The ES detected poliovi...
Source: Food and Environmental Virology - April 24, 2024 Category: Virology Source Type: research
Ethnobotanical assessment of antidiabetic medicinal plants in District Karak, Pakistan
Diabetes is a leading health disorder and is responsible for high mortality rates across the globe. Multiple treatment protocols are being applied to overcome this morbidity and mortality including plant-based... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - April 24, 2024 Category: Complementary Medicine Authors: Amina Nazar, Muhammad Adnan, Syed Majid Shah, Ahmed Bari, Riaz Ullah, Akash Tariq and Nisar Ahmad Tags: Research Source Type: research
Oral mucormycosis associated with COVID-19 and diabetes mellitus: Case report and literature review
We present a case of a patient with diabetes mellitus and diagnosed with oral mucormycosis associated with COVID-19.PMID:38648346 | DOI:10.7705/biomedica.6970 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - April 22, 2024 Category: International Medicine & Public Health Authors: Julio C ésar Velasco Ledmar Jovanny Vargas Lorena Garc ía Iv án José Torres Iv án Camilo González Source Type: research
