Sensorineural hearing loss among type 2 diabetic patients and its association with peripheral neuropathy: a cross-sectional study from a lower middle-income country
Conclusions The study highlights the substantial prevalence of SNHL among patients with T2DM and emphasises the importance of targeted audiological care as part of a holistic approach to diabetes management. Addressing HL early may significantly improve communication and overall quality of life. (Source: BMJ Open)
Source: BMJ Open - May 1, 2024 Category: General Medicine Authors: Asghar, S., Ali, Z., Abdullah, A., Naveed, S., Ahmad, M. S., Rafi, T. S. M. Tags: Open access, Diabetes and Endocrinology Source Type: research

Prevalence of high-risk human papillomavirus in oral squamous cell carcinoma with or without chewing habits
by Namrah Anwar, Qurratulain Chundriger, Sohail Awan, Tariq Moatter, Tazeen Saeed Ali, Maria Abdul Rasheed, Shahid Pervez Oral cancer (OC) is the most common cancer in Pakistani males and the second most common in females. Major risk factors include peculiar chewing habits, human papillomavirus (HPV) infection and molecular pathways. However, less data is available for this avertible cancer regarding its association with high-risk HPV (HR-HPV) and chewing habits in this region. Therefore, this study was done to determine the prevalence of HR-HPV in oral squamous cell carcinoma (OSCC) and its correlation with p16 and chewi...
Source: PLoS One - May 1, 2024 Category: Biomedical Science Authors: Namrah Anwar Source Type: research

Development of palliative care clinical practice guidelines and referral care pathways for primary care practitioners in Pakistan
Despite a large burden of life-limitingillness, there exists a dearth of services of palliative care in Pakistan. International guidelines have questionable applicability in Pakistan due to the socioeconomic d... (Source: BMC Palliative Care)
Source: BMC Palliative Care - May 1, 2024 Category: Palliative Care Authors: Syeda Amrah Hashmi, Russell Seth Martins, Annum Ishtiaq, Nashia Ali Rizvi, Mohsin Ali Mustafa, Alina Pervez, Ayra Siddiqui, Syeda Fatima Shariq, Sarah Nadeem, Adil H. Haider and Muhammad Atif Waqar Tags: Research Source Type: research

Duodenal quantitative mucosal morphometry in children with environmental enteric dysfunction: a cross-sectional multi-country analysis
CONCLUSIONS: Morphometric analysis of duodenal biopsy slides across geographies identified morphologic features of EED, specifically short villi, elongated crypts, and a smaller V:C ratio relative to NPA slides; although not as severe as in celiac slides. Morphometry did not explain other EED features, suggesting that EED histopathologic processes may be operating independently of morphology. While acknowledging the challenges with obtaining relevant tissue, these data form the basis for further assessments of the role of morphometry in EED.PMID:38685382 | DOI:10.1016/j.ajcnut.2024.04.027 (Source: Am J Clin Nutr)
Source: Am J Clin Nutr - April 30, 2024 Category: Nutrition Authors: Lubaina Ehsan David Coomes Paul Kelly Adam R Greene S Asad Ali Chola Mulenga Donna M Denno Kelley VanBuskirk Muhammad Faraz Raghib Mustafa Mahfuz Sean R Moore M Shabab Hossain Tahmeed Ahmed Peter B Sullivan Christopher A Moskaluk Sana Syed EEDBI Consortiu Source Type: research

Duodenal quantitative mucosal morphometry in children with environmental enteric dysfunction: a cross-sectional multi-country analysis
CONCLUSIONS: Morphometric analysis of duodenal biopsy slides across geographies identified morphologic features of EED, specifically short villi, elongated crypts, and a smaller V:C ratio relative to NPA slides; although not as severe as in celiac slides. Morphometry did not explain other EED features, suggesting that EED histopathologic processes may be operating independently of morphology. While acknowledging the challenges with obtaining relevant tissue, these data form the basis for further assessments of the role of morphometry in EED.PMID:38685382 | DOI:10.1016/j.ajcnut.2024.04.027 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 30, 2024 Category: Nutrition Authors: Lubaina Ehsan David Coomes Paul Kelly Adam R Greene S Asad Ali Chola Mulenga Donna M Denno Kelley VanBuskirk Muhammad Faraz Raghib Mustafa Mahfuz Sean R Moore M Shabab Hossain Tahmeed Ahmed Peter B Sullivan Christopher A Moskaluk Sana Syed EEDBI Consortiu Source Type: research

< em > In vitro < /em > Antibacterial Activity of Ethanolic Tanao Si Kan Dang RD1 ( < em > Cannabis sativa < /em > L.) Extracts Against Human Antibiotic-Resistant Bacteria
Conclusion:&lt;/b&gt; This study presents a novel finding regarding the antibacterial activity of ethanolic extracts from the leaves and stems of Tanao Si Kan Dang RD1 against antibiotic-resistant bacteria. The potential application of these cannabis plant extracts in the development of antibiotics capable of combating antibiotic-resistant pathogenic bacteria represents a promising strategy to address a significant global health concern.PMID:38686733 | DOI:10.3923/pjbs.2024.119.124 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - April 30, 2024 Category: Biomedical Science Authors: Nipaporn Armassa Duanpen Wongsorn Benya Saenmahayak Somsak Rayan Surachai Rattanasuk Source Type: research

Effect of Low Protein Diet on Bone Structure of Young Wistar Mice
Conclusion:&lt;/b&gt; A low protein diet decreased the body weight of the rats, also causing impaired bone growth characterized by decreasing femur weight. The low protein diet also caused osteoporosis in the bones.PMID:38686732 | DOI:10.3923/pjbs.2024.113.118 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - April 30, 2024 Category: Biomedical Science Authors: Faysal Kastella Filiani Natalia Salim Hanna Goenawan Ronny Lesmana Rita Maliza Rahimi Syaidah Aziiz Mardanarian Rosdianto Vita Murniati Tarawan None Setiawan Source Type: research

Antioxidant and Antibacterial Properties of 1,3-Dihydroxy-,2', 2'-Dimethylpyrano-(5,6)-Xanthone from < em > Streptomyces < /em > sp. SU84
Conclusion:&lt;/b&gt; The findings suggested that compounds of &lt;i&gt;Streptomyces&lt;/i&gt; sp. SU84 displayed antibacterial and antioxidant properties without cytotoxic activity. Extensive studies of compound &lt;b&gt;1&lt;/b&gt; may be useful for the advancement of improved methods for avoidance, control and management of bacterial infections and metabolic-related free radical contribution.PMID:38686735 | DOI:10.3923/pjbs.2024.132.141 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - April 30, 2024 Category: Biomedical Science Authors: Thongchai Taechowisan Thanaporn Chuen-Im Waya S Phutdhawong Source Type: research

Doxorubicin, doxorubicinol, cardiotoxicity, breast cancer, volumetric absorptive microsampling, LC-MS/MS
Conclusion:&lt;/b&gt; Dosage cumulative doxorubicin ranges between 47.93 and 346.09 mg/m&lt;sup&gt;2&lt;/sup&gt;; with this, the risk of cardiomyopathy in the patients surveyed is under 4%, according to the literature.PMID:38686734 | DOI:10.3923/pjbs.2024.125.131 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - April 30, 2024 Category: Biomedical Science Authors: Dian Fitri Chairunnisa Yahdiana Harahap Maria Juanita Nadia Farhanah Syafhan Denni Joko Purwanto Source Type: research

Effectiveness of Gel from Andaliman Fruit ( < em > Zanthoxylum acanthopodium < /em > DC.) Extract on Wound Inflammation
Conclusion:&lt;/b&gt; Finally, analgesic gel spray made from the Andaliman fruit at a 15% concentration can help with pain and also be antibacterial, reduce inflammation and help wounds heal.&lt;/p&gt.PMID:38686736 | DOI:10.3923/pjbs.2024.142.151 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - April 30, 2024 Category: Biomedical Science Authors: Elsa Izza Sabila Annisa Ayu Ramadhani Hanif Fadhilah Balqis Nur Nasution None Fathiya Putri Cahaya Situmorang Source Type: research

GC-MS and ATR-FTIR Spectroscopy Coupled with Chemometric Analysis for Detection and Quantification of White Turmeric ( < em > Curcuma zedoaria < /em > ) Essential Oils Adulteration
Conclusion:&lt;/b&gt; The FTIR and chemometrics combination effectively authenticates white turmeric essential oil from any possible adulterants, such as vegetable oil.PMID:38686738 | DOI:10.3923/pjbs.2024.160.167 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - April 30, 2024 Category: Biomedical Science Authors: Suryati Syafri Ghada Nabila Gari Lindo Yohannes Alen Syofyan Syofyan Dachriyanus Hamidi Source Type: research

Antioxidant and Antimicrobial Potential of Peptide from Rabbit Meat Hydrolysate Prepared by Trypsin and Zingibain
Conclusion:&lt;/b&gt; The combination zingibain enzyme and trypsin is feasible for hydrolyzing rabbit meat and the optimum hydrolysis time was 24 hrs with IC&lt;sub&gt;50&lt;/sub&gt; 52.45 ppm, although accompanied by reduction in antibacterial activities.PMID:38686737 | DOI:10.3923/pjbs.2024.152.159 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - April 30, 2024 Category: Biomedical Science Authors: Eka Wulandari Wendry Setiyadi Putranto Andry Pratama Jajang Gumilar Rani Maharani Source Type: research

Duodenal quantitative mucosal morphometry in children with environmental enteric dysfunction: a cross-sectional multi-country analysis
CONCLUSIONS: Morphometric analysis of duodenal biopsy slides across geographies identified morphologic features of EED, specifically short villi, elongated crypts, and a smaller V:C ratio relative to NPA slides; although not as severe as in celiac slides. Morphometry did not explain other EED features, suggesting that EED histopathologic processes may be operating independently of morphology. While acknowledging the challenges with obtaining relevant tissue, these data form the basis for further assessments of the role of morphometry in EED.PMID:38685382 | DOI:10.1016/j.ajcnut.2024.04.027 (Source: Am J Clin Nutr)
Source: Am J Clin Nutr - April 30, 2024 Category: Nutrition Authors: Lubaina Ehsan David Coomes Paul Kelly Adam R Greene S Asad Ali Chola Mulenga Donna M Denno Kelley VanBuskirk Muhammad Faraz Raghib Mustafa Mahfuz Sean R Moore M Shabab Hossain Tahmeed Ahmed Peter B Sullivan Christopher A Moskaluk Sana Syed EEDBI Consortiu Source Type: research

Duodenal quantitative mucosal morphometry in children with environmental enteric dysfunction: a cross-sectional multi-country analysis
CONCLUSIONS: Morphometric analysis of duodenal biopsy slides across geographies identified morphologic features of EED, specifically short villi, elongated crypts, and a smaller V:C ratio relative to NPA slides; although not as severe as in celiac slides. Morphometry did not explain other EED features, suggesting that EED histopathologic processes may be operating independently of morphology. While acknowledging the challenges with obtaining relevant tissue, these data form the basis for further assessments of the role of morphometry in EED.PMID:38685382 | DOI:10.1016/j.ajcnut.2024.04.027 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 30, 2024 Category: Nutrition Authors: Lubaina Ehsan David Coomes Paul Kelly Adam R Greene S Asad Ali Chola Mulenga Donna M Denno Kelley VanBuskirk Muhammad Faraz Raghib Mustafa Mahfuz Sean R Moore M Shabab Hossain Tahmeed Ahmed Peter B Sullivan Christopher A Moskaluk Sana Syed EEDBI Consortiu Source Type: research

< em > In vitro < /em > Antibacterial Activity of Ethanolic Tanao Si Kan Dang RD1 ( < em > Cannabis sativa < /em > L.) Extracts Against Human Antibiotic-Resistant Bacteria
Conclusion:&lt;/b&gt; This study presents a novel finding regarding the antibacterial activity of ethanolic extracts from the leaves and stems of Tanao Si Kan Dang RD1 against antibiotic-resistant bacteria. The potential application of these cannabis plant extracts in the development of antibiotics capable of combating antibiotic-resistant pathogenic bacteria represents a promising strategy to address a significant global health concern.PMID:38686733 | DOI:10.3923/pjbs.2024.119.124 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - April 30, 2024 Category: Biomedical Science Authors: Nipaporn Armassa Duanpen Wongsorn Benya Saenmahayak Somsak Rayan Surachai Rattanasuk Source Type: research