The Wheat Belly Timeline: The First Few Weeks
With all our talk of opiate withdrawal syndromes accompanied by nausea, headache, fatigue, and depression, it can be daunting, even terrifying, to people who face the prospect of tossing all wheat and grains into the trash bin, vowing to never let a Danish, donut, or dish of pasta cross your lips again. So it may help to lay out a timeline of what and when various changes can develop in the Wheat Belly wheat- and grain-free lifestyle.
You can expect different symptoms and health conditions to recede at different rates, since they are caused by a variety of different mechanisms. For instance, the direct gastrointestinal tox...
Source: Wheat Belly Blog - October 26, 2018 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle acid reflux detoxification grains IBS Inflammation joint pain opiates withdrawal Source Type: blogs
Fight Aging! Newsletter, October 22nd 2018
In this report, we propose that the molecular mechanisms of beneficial actions of CR should be classified and discussed according to whether they operate under rich or insufficient energy resource conditions. Future studies of the molecular mechanisms of the beneficial actions of CR should also consider the extent to which the signals/factors involved contribute to the anti-oxidative, anti-inflammatory, anti-tumor and other CR actions in each tissue or organ, and thereby lead to anti-aging and prolongevity.
RNA Interference of ATP Synthase Subunits Slows Aging in Nematodes
https://www.fightaging.org/archives...
Source: Fight Aging! - October 21, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Anti-Amyloid CPHPC Therapy Used in a Clinical Trial for Alzheimer's Disease
CPHPC, now called miridesap, is a cautionary tale of what all too often happens to promising approaches in the field of medical development, once they advance to the point of expensive clinical trials and the requirement for partners with deep pockets to fund those trials. Miridesap was one of the earlier methodologies demonstrated to clear out transthyretin amyloid from tissues. This form of amyloid appears to be an important contribution to risk of cardiovascular disease, as well as a factor in osteoarthritis, and the evidence suggests it is the majority cause of death in supercentenarians. Its accumulation in old tissue...
Source: Fight Aging! - October 18, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, October 15th 2018
This study suggests that exocrine glands can be induced from pluripotent stem cells for organ replacement regenerative therapy.
Replacement of Aged Microglia Partially Reverses Cognitive Decline in Mice
https://www.fightaging.org/archives/2018/10/replacement-of-aged-microglia-partially-reverses-cognitive-decline-in-mice/
Researchers here report on a compelling demonstration that shows the degree to which dysfunctional microglia contribute to age-related neurodegeneration. The scientists use a pharmacological approach to greatly deplete the microglial population and then allow it to recover naturally. Th...
Source: Fight Aging! - October 14, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Navigating back pain treatments: Can a physiatrist help?
If self-care steps for back pain such as gentle activity, local heat, or massage don’t ease discomfort within a few weeks to a month, or if you struggle with chronic low back pain, a physiatrist can help you navigate the dizzying number of treatment options. These range from conservative therapies (such as medicines, physical therapy, and chiropractic care) to more invasive options (such as spine injections and spinal surgery).
What is a physiatrist?
Physiatrists are medical doctors who specialize in physical medicine and rehabilitation. We focus on holistic, nonsurgical care aimed at improving function for people who ar...
Source: Harvard Health Blog - October 10, 2018 Category: Consumer Health News Authors: Edward N. Wei, MD Tags: Back Pain Bones and joints Health Pain Management Source Type: blogs
The Popular Press in Better Form on Senolytic Research and Development
Research programs and investment in commercial development related to senolytic therapies are growing rapidly, particularly in the last couple of years. As today's article demonstrations, journalists in the popular press are improving when it comes to their ability to report sensibly on these developments. This has taken far too long to come to pass; it wasn't all that long ago that near every article in the media on the prospects for treating aging was some combination of nonsense, scorn, and fear-mongering.
Senolytic treatments are those that selectively destroy senescent cells in aged tissues. The accumulation of...
Source: Fight Aging! - October 8, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
On “ us ” and “ them ” : what if we ’ re one of “ them ” ?
Over the past few years I’ve been pondering the presumed gap between people living with pain and the people who “treat” or work with them. Most of my readers will know that I live with widespread pain (aka fibromyalgia) or pain that is present in many parts of my body, and the associated other symptoms like DOMS that last for weeks not a day or two, and increased sensitivity to heat, cold, pressure, chilli, sound and so on.
I first “came out” with my pain about 15 years ago: that is, I first disclosed to people I worked with that I had this weird ongoing pain – and finally joined the...
Source: HealthSkills Weblog - October 7, 2018 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Professional topics Research Therapeutic approaches inclusion inequality Source Type: blogs
Fight Aging! Newsletter, October 8th 2018
This article, unfortunately paywalled, is interesting to note as a mark of the now increasingly energetic expansion of commercial efforts in longevity science. David Sinclair has been building a private equity company to work in many areas relevant to this present generation of commercial longevity science; while I'm not sold on his primary research interests as the basis for meaningful treatments for aging, he is diversifying considerably here, including into senolytics, the clearance of senescent cells demonstrated to produce rejuvenation in animal studies. This sort of approach to business mixes aspects of investing and...
Source: Fight Aging! - October 7, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Life Biosciences: David Sinclair Aims to be a Major Player in the Present Generation of Commercial Longevity Science
This article, unfortunately paywalled, is interesting to note as a mark of the now increasingly energetic expansion of commercial efforts in longevity science. David Sinclair has been building a private equity company to work in many areas relevant to this present generation of commercial longevity science; while I'm not sold on his primary research interests as the basis for meaningful treatments for aging, he is diversifying considerably here, including into senolytics, the clearance of senescent cells demonstrated to produce rejuvenation in animal studies. This sort of approach to business mixes aspects of investing and...
Source: Fight Aging! - October 3, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Illusions as Painkillers: the Analgesic Value of Resizing Illusions in Knee Osteoarthritis - Scientific American
Research has shown that the experience of pain is highly subjective: people feel more or less pain, in identical physical situations, as a function of their mood and attention. This flexibility showcases the potential for cognitive manipulations to decrease the pain associated with a variety of pathologies. As an example, the virtual-reality game"Snow World" (in which game in which players shoot snowballs to defeat snowman Frosty and his penguins) reportedly works better than morphine at counteracting the pain of patients in burn units. Other studies have indicated that virtual reality manipulations of the patien...
Source: Psychology of Pain - September 21, 2018 Category: Anesthesiology Source Type: blogs
Fight Aging! Newsletter, September 17th 2018
In this study, we found that TXNIP deficiency induces accelerated senescent phenotypes of mouse embryonic fibroblast (MEF) cells under high glucose condition and that the induction of cellular ROS or AKT activation is critical for cellular senescence. Our results also revealed that TXNIP inhibits AKT activity by a direct interaction, which is upregulated by high glucose and H2O2 treatment. In addition, TXNIP knockout mice exhibited an increase in glucose uptake and aging-associated phenotypes including a decrease in energy metabolism and induction of cellular senescence and aging-associated gene expression. We propose that...
Source: Fight Aging! - September 16, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Reporting on the 2018 International Cellular Senescence Association Meeting
Research into cellular senescence is at present one of the most exciting areas of the science of aging, as it is in this part of the scientific community that the first real, actual, legitimate rejuvenation therapies were discovered. These senolytic treatments, capable of selectively destroying senescent cells, are now in the process of verification in human trials. They offer the possibility of significant reversal of all inflammatory age-related disease, to a far greater degree than can be offered by any past therapy: osteoporosis; the fibrosis that drives dysfunction of the lung, heart, and kidney; neurodegenerative con...
Source: Fight Aging! - September 12, 2018 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Fever with polyarthralgia – Medicine MCQ – CVS – Answer
Fever with polyarthralgia – Medicine MCQ – CVS – Answer
Medicine MCQs – CVS: on Amazon Kindle Store
Person presents with fever of 2 weeks and polyarthralgia. Which of the following findings will you specifically look for in the hands:
Correct answer: c) Splinter hemorrhages
From the point of view of cardiovascular system, prolonged fever with polyarthralgia could be a manifestation of infective endocarditis. Rheumatic fever seldom presents as prolonged fever. Striking manifestation is usually polyarthritis in rheumatic fever.
Heberden’s nodes are seen in osteoarthritis. Cyanosis has no specific...
Source: Cardiophile MD - September 4, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Uncategorized Source Type: blogs
Fight Aging! Newsletter, September 3rd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - September 2, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Articles on Senolytics are Starting to Look Just Like Articles on any Other Field of Medical Research and Development
It is probably worthy of note that press articles on the treatment of aging via senolytic therapies are becoming similar in tone and content to press articles on any other active field of medical development. Take this example, publicity for Unity Biotechnology and their work on senolytic therapies to clear senescent cells from old tissues and thus remove one of the contributing causes of aging and age-related disease. It is formatted as a discussion of trials, funding, and this company or that company, this lab or that lab. It exhibits little of the breathless nonsense as to why we shouldn't address aging and its conseque...
Source: Fight Aging! - August 31, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
