Fight Aging! Newsletter, September 3rd 2018

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is published under the Creative Commons Attribution 4.0 International License. You are encouraged to republish and rewrite it in any way you see fit, the only requirements being that you provide attribution and a link to Fight Aging! To subscribe or unsubscribe please visit: https://www.fightaging.org/newsletter/ Contents An Examination of the Link Between Chronic Inflammation and Cognitive Decline First Generation Pharmaceutical Treatments for Transthyretin Amyloidosis Continue to Make Progress The Futility of Attempts to Rigorously Distinguish Age-Related Disease from Aging The State of Evidence for a Novel TP53-DHEAS Anti-Cancer Mechanism in Primates Cellular Senescence is One of the Causes of Age-Related Decline of Liver Regeneration An Update on a Human Telomerase and Follistatin Gene Therapy Mitochondrial Mechanisms Link ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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CONCLUSIONS: In patients with T2DM and CKD, SGLT2 inhibitors have a decreased glucose-lowering effect compared to patients without CKD. Renal benefits among patients with CKD are similar to those without CKD and include a significant reduction in albuminuria and reduced incidence of worsening albuminuria. Given that CKD and T2DM are both associated with increased cardiovascular risk, we believe these agents should considered as preferred add-on agents in most patients with uncontrolled T2DM and eGFR>30 ml/min/1.73m2. Ongoing studies will provide additional information as to whether these agents should be added to the cu...
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
The β-blocker uptitration in elderly with heart failure regarding biomarker levels: CIBIS-ELD substudy. Biomark Med. 2018 Nov 19;: Authors: Cvetinovic N, Sekularac N, Haehling SV, Tahirovic E, Inkrot S, Lainscak M, Apostolovic S, Putnikovic B, Waagstein F, Gelbrich G, Aleksic A, Loncar G, Düngen HD Abstract AIM: We investigated if the baseline value of mid-regional pro-atrial natriuretic peptide (NP), N-terminal pro-B-type NP and copeptin may be helpful in optimizing β-blocker uptitration in elderly patients with heart failure. PATIENTS &METHODS: According to the biomarkers'...
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
BOSTON (CBS) – It’s a unique medical school class designed to increase awareness of patients with autism and other intellectual disabilities. And today’s teachers were two teenagers, both on the autism spectrum. “I’m 13 years old. I’m in eighth grade. I really, really like otters, and I have ADHD and a tiny bit of autism,” says Hana. She and her 15-year-old sister Helen have come to a Boston University Medical School classroom to talk with third year students. Both girls are on the autism spectrum, and are ready for any and all questions. “Anything! I’m not going to ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated Local Watch Listen Autism Boston University School Of Medicine Paula Ebben Source Type: news
Authors: Oze I, Ito H, Nishino Y, Hattori M, Nakayama T, Miyashiro I, Matsuo K, Ito Y Abstract BACKGROUND: Lung cancers are classified into small-cell lung cancer (SCLC) and non-small-cell lung cancer due to their different treatment and prognosis. Although many studies have reported the specific survival of SCLC patients treated at cancer hospitals, survival from population-based data has rarely been reported. METHODS: We analyzed survival of SCLC cases diagnosed from 1993 through 2006 from a population-based cancer registry of six prefectures. To assess trends in SCLC survival, we defined three periods that m...
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
CONCLUSIONS: Only women showed an income-based gradient in diabetes. Monitoring income gradient in diabetes is important in public health actions, even in older populations. Future longitudinal and intervention studies should evaluate the causal link of income to diabetes onset, determine the mechanisms of the potential sex differences in the income/diabetes association, and identify ways to mitigate the income-based inequality. PMID: 30449769 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
An immunotherapy drug may allow allergy sufferers lead more normal lives.
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Mylan NV said on Tuesday it would recall certain batches of blood pressure medicine valsartan in the United States after they were found to contain a probable cancer-causing impurity, the latest recall amid heightened safety concerns globally.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Adherence to the Mediterranean diet is significantly associated with a reduction over time in beta-amyloid accumulation, a biomarker of cerebral Alzheimer's disease pathology, new research suggests.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Psychiatry News Source Type: news
Shu-Qing Zuo, Xiu-Jun Li, Zhi-Qiang Wang, Jia-Fu Jiang, Li-Qun Fang, Wen-Hui Zhang, Jiu-Song Zhang, Qiu-Min Zhao, Wu-Chun Cao
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Public health officials in the United States and Canada on Tuesday warned against eating romaine lettuce while they investigate an outbreak of E. coli that has sickened 50 people in the two countries, including 13 who were hospitalized.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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