TRP Antibodies
Some of the Best AvailableOur TRP Channel Antibodies are widely used and frequentlypublished.Here ' s some data from researchers using on of ourTRPV1 Antibodies.Immunohistochemical expression of serum response factor in rat dorsal root ganglia. Dorsal root ganglia dissected from male Sprague-Dawley rat and imaged by confocal microscopy for (A) TRPV1 (blue), (B) AKAP (AKAP150, green), and (C) SRF (red), with colocalization represented in panel (D). White arrows indicate cells expressing all 3 proteins. Yellow line represents 50 μM in length; images are representative of 4 individual sections taken from 6 L4 to L6 DRG. (E) ...
Source: Neuromics - October 18, 2018 Category: Neuroscience Tags: Transient Receptor Potential Vanilloid 1 Receptor Antibodies TRP antibody TRPV1 antibodies TRPV1 antibody VR1s Source Type: news

Neuromics New Neuronal Markers
Best of the BestWe are recognized for having some of the bestNeuronal-Glial Antibodies in the business. We are pleased to announce the addition of these:CH22122– Tyrosine HydroxylaseGT22101 - GFPGT22102– MAP2GT22103 - VimentinMO22186– Tyrosine HydroxylaseRA22135– Tyrosine HydroxylaseImmunofluorescent analysis of rat brainstem section stained withGT22102, MAP2dilution 1:2,000 in red, and costained with mouse mAb to MO22121, MBP dilution 1:5,000, in green. Following transcardial perfusion of rat with 4% paraformaldehyde, brain was postfixed for 24 hours, cut to 45 μM, and free-floating sections were stained with the...
Source: Neuromics - October 7, 2018 Category: Neuroscience Tags: Immunofluorescence MAP2 antibody MBP Antibody Myelin Basic Protein TH antibody Tyrosine Hydroxlase antibody Western Blotting Source Type: news

Quality FBS-Only 259 USD/500 ml.
First Come; First ServeWe have an inventory of FBS of approximately 2000 bottles.  This inventory includes the lots we ' ve been selling and using internally all year.  These have proven to be of the highest quality.Here ’s a sampling of user feedback: After a referral from an ex-colleague, we tested a sample from a single batch and found that the product is great for cell cloning& hybridoma work, and generally for all other cell culture. We subsequently ordered several bottles of FBS. The sales person was very friendly and worked with me to make the purchase possible. The order arrived promp...
Source: Neuromics - September 30, 2018 Category: Neuroscience Tags: 3-D Cell based Assays Cell Cultures FBS Fetal Bovine Serum Source Type: news

Human Brain Microvascular Endothelial Cell in Action
Recent PubsOur HumanBrain Microvascular Endothelial Cells (HBMECs) are known for the performance in drug discovery and tox assays. These 21-CFR compliant cells are used in the " blood side " of our3-D BBB Models.Shavali Shaik, Bridget Kennis, Shinji Maegawa, Keri Schadler, Yang Yanwen, Keri Callegari, Rishi R. Lulla, Stewart Goldman, Javad Nazarian, Veena Rajaram, Jason Fangusaro, and Vidya Gopalakrishnan. (2018).REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature. Oncotarget. 2018 Jan 12; 9(4): 5233 –5250. doi: 10.18632/oncotarget.23750 Hu et al. (2016). Epigenetic Activation of WNT5A ...
Source: Neuromics - September 20, 2018 Category: Neuroscience Tags: Blood Brain Barrier Blood Brain Barrier Models brain microvascular endothelial cells HBMECs human brain microvascular Source Type: news

Neuromics' BBB Model and Permeability Assays
Crossing the Blood-Brain BarrierOur BBB Model is being increasingly used by Bio-Pharma for drug permeability studies. Customers include Amgen, Genentech, Boehringer Ingelheim, and Merck.These assays are key for making sure molecules/compounds of interest will cross the barrier into the brain and at what rate. This data, in part, add clarity on best candidates to move intoin-vivotesting. Human Blood Brain Barrier Model 3D4500212 well Human Blood Brain Barrier Model 3D4500224 well Human Blood Brain Barrier Model 3D450026 wellsI you have interest in using our models, Rose Ludescher, Manager of Customer Satisfaction...
Source: Neuromics - September 14, 2018 Category: Neuroscience Tags: Astrocytes BBB Model Blood Brain Barrier Blood Brain Barrier Models brain microvascular endothelial cells Pericytes Source Type: news

Energize your Cell-Based Assays
Check out our AlphaBioCoat Collagen is a fibrous protein found in the extracellular matrix and connective tissue. The most common form of collagen is type I and is most prevalent in bone, tendon and skin. It consists of 3 intertwined coiled subunits: 2 x α1 (I) chains and 1 x α2 (I) chain. Each chain contains 1050 amino acids wound tightly around one another in a characteristic right-handed triple helix. The triple-helical structure of collagen arises from unique abundance of the amino acids in collagen appear in a characteristic repeating motif G ly-X-Y, where X is usually proline and Y is usually hydroxyproline.Al...
Source: Neuromics - August 27, 2018 Category: Neuroscience Tags: AlphBioCoat Cell Cultures cell culturing protocol Source Type: news

Human Brain Cells
Our ExpertiseWhen researchers are considering using ourhuman brain cells, they often voice concerns about growth. In order to address these concerns, we explain that we have optimized our media and coatings in order to meet their assay needs.Here ' s an example of how ourhuman brain pericytes grow over time.We have primary human neurons, astrocytes, microglia and Schwann cells.If you have interest you can contact us at 866-350-1500 or rose@neuromics.com. We will provide the information required to help you make an informed decision. (Source: Neuromics)
Source: Neuromics - August 16, 2018 Category: Neuroscience Tags: astrocyte cultures Culturing Human Neurons Protocol Human Microglia human primary astrocytes human primary microglia Human Primary Neurons human primary schwann cells Source Type: news

Human Brian Cells
Our ExpertiseWhen researchers are considering using ourhuman brain cells, they often voice concerns about growth. In order to address these concerns, we explain that we have optimized our media and coatings in order to meet their assay needs.Here ' s an example of how ourhuman brain pericytes grow over time.We have primary human neurons, astrocytes, microglia and Schwann cells.If you have interest you can contact us at 866-350-1500 or rose@neuromics.com. We will provide the information required to help you make an informed decision. (Source: Neuromics)
Source: Neuromics - August 16, 2018 Category: Neuroscience Tags: astrocyte cultures Culturing Human Neurons Protocol Human Microglia human primary astrocytes human primary microglia Human Primary Neurons human primary schwann cells Source Type: news

New Neuronal Markers
Check Them Out!We continue to addnew antibodies. Many are additions to our frequently used and widely publishedNeuron-Glial Markers.Image: Immunofluorescent analysis of cortical neuron-glial cell culture from E20 rat stained with mouse mAb to GAP43, MO22170, dilution 1:1,000, in red, and costained with chicken pAb to MAP2, dilution 1:10,000, in green. The blue is DAPI staining of nuclear DNA. GAP43 antibody labels protein expressed in the axonal membrane of the neuronal cells, while the MAP2 antibody stains dendrites and perikarya of neurons. Name Species Applications Aurora A/B Kinase Human, Mouse, Rat ICC, WB, IHC,...
Source: Neuromics - August 7, 2018 Category: Neuroscience Tags: DJ1 Antibody GAP43 Antibody Ki67 antibody. Vimentin Antibody nestin antibody OPA1 Antibody Tuj 1 antibody Source Type: news

Easy Immunostaining Staining
10X the Signal at a Fraction of the CostTime is money. This is especially true of routine immunostaining assays.We are pleased to introduce you toEZ-HRPTM Polymer Detection. Features include:10-15 times more sensitive than conventional avidin-biotin detection Allows for entire staining procedure to be completed in just under 2 hours Requires less primary antibody (3-4 times less) Does not produce non-specific background staining Can be used on unfixed or chemical fixed (formalin, formaldehyde, alcohol, etc), paraffin-embedded and frozen tissue sections.Comparison of IHC images using EZ-HRP ™ Polymer vs. a conve...
Source: Neuromics - July 31, 2018 Category: Neuroscience Tags: HRP-Staining. Immunofluorescence Immunonostaining Source Type: news

Our Hearing Adapts in Space
This study uses ourShank 1a Antibody to determine changes in the neuronal structure of the ear in microgravity.Image: Verification of antibodies to CtBP2 and Shank1a. A and B: serial 14- µm cryosections were obtained from a postnatal day 71 (P71) mouse utricle, and maximum-intensity projections are shown. Hair cell (hc) and support cell (sc) nuclei are illuminated by the DAPI stain (blue). Numerous closely associated CtBP2-and Shank1a-positive puncta can be observed in the positive immunostained section represented in A (block arrowheads). The CtBP2-positive puncta highlighted by the flared arrowhead in A may re...
Source: Neuromics - July 24, 2018 Category: Neuroscience Tags: hair cells microgravity Shank 1a antibody Source Type: news

Staining Cells and Tissue
The background is Bad!Yes, it is. It compromises data. We have a solution.FluoMuteTMFluoMute ™ ready-to-use reagent to reduce autofluorescence in cells and tissue. Just incubate fixed cells of tissue sections with FluoMute™ for 30-60 min at room temperature, rinse with PBS and continue with immunofluorescence ICC or/and IHC protocols. Treatment with FluoMute™ does not affect cell morp hology and the integrity of tissue antigens to be detected with primary antibodies (see bottom image). FluoMute™ is compatible with paraffin-embedded and frozen tissue sections, stem cells, lymphocytes and mammalian cell lines of diff...
Source: Neuromics - July 19, 2018 Category: Neuroscience Tags: autofluorescence FluoMute Source Type: news

Human Cells in Action
Human Microvascular Retinal Endothelial Cells (HMRECS)We have built the foundation ofNeuromics on satisfied customers. We make a practice of following up with each user to make sure our solutions are working as expected. If not, we offer " no question asked " refunds or replacements.This is especially important for ourhuman cells,media, and supplements. Success with these is easy to measure as either the cells are healthy and happy or they are not.We also usereviews andpublications as another measure of satisfaction. Here I would l highlight the latest publication using ourHREMCS. A. P. Da Cunha, Q. Zhang, M. Pre...
Source: Neuromics - July 11, 2018 Category: Neuroscience Tags: Culturing Media endothelial cells FBS Fetal Bovine Serum HRMECS Human Endothelial Cells Source Type: news

Neuromics' Fetal Bovine Serum (FBS) Strikes Again
Potent FBS at Pricing You ' ll LikeNeuromics started providingFBS to researchers in early 2017. Our goal was to provide thorough tested and 9-CFR compliant FBS with the lowest pricing anywhere.In order to ensure our initial claims are trustworthy, we follow up with all our users and ask that they providefeedback. Here ' s the latest review-Ordered Fetal bovine serum. Best price and quality" - Juwen D, Albert Einstein College of Medicine. Product: Heat-inactivated FBS, cat no. FBS001-HI.We are now starting to see the use of our FBS reference in publications: Am élie Robert, Peirun Tian, Stephen A. Adam, Mark...
Source: Neuromics - July 2, 2018 Category: Neuroscience Tags: 3-D Cell based Assays cell biology Cell Cultures FBS Fetal Bovine Serum Source Type: news

You'll Love our FBS!
Check out Testimonials from UsersNeuromics is proud to offer you the high-quality Fetal Bovine Serum, the same serum we use internally, without the high cost. Our customers, researchers like you, agree.Ordered Fetal bovine serum. Best price and quality" - Juwen D, Albert Einstein College of Medicine. Product: Heat-inactivated FBS, cat no. FBS001-HIOutstanding service. Fetal bovine serum was of highest quality, easy to order and packaging and shipping were best possible. " - Rosemary, University of Buffalo Product: Heat-inactivated FBS, cat no. FBS001-HI (see all of Neuromics reviews here)...
Source: Neuromics - June 28, 2018 Category: Neuroscience Tags: FBS Fetal Bovine Serum Source Type: news