Malaria and the Blood-Brain Barrier
 EPCR and ICAM ReceptorsNeuromicsAstrocytes and Pericytes were used in this important study-Yvonne Adams, Rebecca W. Olsen, Anja Bengtsson, Nanna Dalgaard, Mykola Zdioruk, Sanghamitra Satpathi, Prativa K. Behera, Praveen K. Sahu, Sean E. Lawler, Klaus Qvortrup, Samuel C. Wassmer, and Anja T.R. Jensen. (2021).Plasmodium Falciparum Erythrocyte Membrane Protein 1 Variants Induce Cell Swelling and Disrupt the Blood –Brain Barrier in Cerebral Malaria. Journal of Experimental Medicine, 218 (3). doi: 10.1084/jem.20201266.This is the first study showing malaria pericytes interacting with human endothelial cells. Please note...
Source: Neuromics - February 1, 2021 Category: Neuroscience Tags: 3-D Blood-Brain Barrier Model –brain barrier penetration brain microvascular endothelial cells human Astrocytes Human Endothelial Cells Human Pericytes Source Type: news

Human Schwann Cells that Work
 No Doubt!Sometimes we hear our human cells did not express a certain receptor in the hands of our customers. We guarantee our cell " walk and talk " as advertised. If you are ever in doubt. we will test for expression of any receptors or cytoplasmic proteins. We also do this as part of our quality checks.Here ' re, for example, is a pub showing our Schwann Cells working. Note the receptors tested here. Seung Min Shin, Francie Moehring, Brandon Itson-Zoske, Fan Fan, Cheryl L. Stucky, Quinn H. Hogan, and Hongwei Yu. (2021). Piezo2 Mechanosensitive Ion Channel is Located to Sensory Neurons and Non-Neuronal Cells in Rat ...
Source: Neuromics - January 26, 2021 Category: Neuroscience Tags: chronic pain human primary primary human cells Schwann Cell Markers Schwann Cells Source Type: news

Cancer Associated Fibroblasts (CAFS) Traction Dynamics and Remodeling in 3D Matrices
 Neuromics ' Colorectal CAFS in ActionIn a first of its kind study, the mechanical properties of ourCAFS were determined. This is important because, understanding how these cell behavein vivowill help improve the efficacy of new therapies: Bashar Emon, Zhengwei Li, Md Saddam Hossain Joy, Umnia Doha, Farhad Kosari, and M Taher A Saif. (2020).A Novel Method for Sensor-Based Quantification of Single/Multi-Cellular Traction Dynamics and Remodeling in 3D Matrices. bioRxiv. doi: 10.1101/2020.09.24.311647" Cells in vivo generate mechanical forces (traction) on surrounding 3D extra cellular matrix (ECM) and cells. Such tracti...
Source: Neuromics - November 25, 2020 Category: Neuroscience Tags: 3-D Assays. 3-D imaging CAFs Cancer Associated Fibroblasts colorectal CAFs Colorectal Cancer Source Type: news

Neuromics' n-Fect Delivers
 Gene Expression Tools in ActionNeuromics has a wide offering of transfection reagents that are perfect for both in vivo and in vitro applications. We take pride in seeing our product used in research, which is certainly true of our transfection reagents (see here).Furthermore, we ' d like to highlight a recent use of our n-Fect Transfection Kit (cat.# NF30150) in a doctoral thesis recently published. The paper looked into the neuroscience of alcohol addiction, looking towards the purinergic family receptor P2X4, which has been linked to alcohol addiction in mouse...
Source: Neuromics - October 23, 2020 Category: Neuroscience Tags: gene expression analysis p-Fect Transfection Source Type: news

Premium Virus Transport Media vs PBS
 There is a differenceHere ' s a video that illustrates the difference between CDC recommended Virus Transport Media and Sterile PBS (salt water). It answers the questions " what is in your VTM " and " why does it matter " . Please consider sharing so it can find its way to those in need!Check out our VTM-https://www.neuromics.com/virus-transport-media (Source: Neuromics)
Source: Neuromics - September 19, 2020 Category: Neuroscience Tags: COVID-19 Test Kits COVID-19 Transport Media PBS Phosphate Buffered Saline Virus Transport Media Source Type: news

Method of treating central nervous system disease
 Blood-Brain Barrier (BBB) Permeability AssayYes, These are troubled times. With our current focus on eradicating COVID-19, we forget that many of the world ' s most insidious and costly diseases have limited treatments and no cures.That is why Neuromics continues to develop its human based 3-D Cell-Based Assays. At the center if our offerings is ourBBB Model.Here ' s a recent patent application that includes a permeability assay using our model-Sookhee Bang, Jeong Kuen Song, Seung-wook Shin, Kwan Hee Lee, and Ho June Lee. (2020).Method of Treating Central Nervous System Disease. United States Patent Application 20200...
Source: Neuromics - August 20, 2020 Category: Neuroscience Tags: 3-D Assays. 3-D imaging 3-D Blood-Brain Barrier Model 3-D Cell Culturing Blood Brain Barrier Blood Brain Barrier Models –brain barrier penetration Source Type: news

What's In Your Virus Transport Media (VTM)
(Source: Neuromics)
Source: Neuromics - August 14, 2020 Category: Neuroscience Source Type: news

We Have FBS in Bulk Available
Key Component of Virus Transport Media (VTM)Neuromics is known to have some of the bestFetal Bovine Serum (FBS)for most applications. This includes being a component ofVTM manufactured to the CDC ' s most recommended recipe.Unlike some other suppliers, we are fully transparent as to pricing and available inventory. Check us out today. (Source: Neuromics)
Source: Neuromics - July 27, 2020 Category: Neuroscience Tags: FBS Fetal Bovine Serum Virus Transport Media VTM Source Type: news

We Have VTM in Bulk
At Capacity for VTM Based COVID-19 Sample Transport KitsWe are well on our way to delivering 100,000 Tubes + VTM to the state of Ohio. A big thank you to my  team and friends for making this happen.5,000 Tubes+VTM Ready to Ship to OhioWe do have a capacity to provide 4,000 Liters/Week ofVTM in 1 Liter Bottles.If you have current or future needs do not hesitate to contact me directly @ pshuster@neuromics.com or direct phone 612-801-1007. Pete Shuster, Owner, Neuromics (Source: Neuromics)
Source: Neuromics - June 25, 2020 Category: Neuroscience Tags: COVID-19 Storage Media COVID-19 Test Kits COVID-19 Transport Media Virus Transport Media VTM Source Type: news

We Have VTM and COVID19 Test Kits
Providing Kits Coast to Coast and Points in BetweenFrom Seattle, Washington to New York City and in between, ourVirus Transport Medium has been used in COVID-19 testing. Neuromics is doing our part by helping to expand testing capacity, allowing the nation to recover from the harships associated with the pandemic.Our VTM is manufactured using ourFBS following CDC guidelines, ensuring that it is sterile and safe for testing. Additionally, each lost of VTM goes through quality control before release (sample CoA). We offer our VTM in many different forms, including kits (tubes and sterile swabs) and larger quantities tha...
Source: Neuromics - May 16, 2020 Category: Neuroscience Tags: COVID-19 Storage Media COVID-19 Test Kits FBS Fetal Bovine Serum Source Type: news

We Have Virus Transport Media (VTM) in Tubes
VTM The Way You Need ItWe have Virus Transport Media in tubes with 2 options.SizePriceVTM-1: 2 ml 15 ml tube (100 mm) - qty 15 (Available after 4/24)$69.00VTM-2: 2 ml 15 ml tube (120 mm) - qty 15$74.00We can also provide tubes with custom volumes of VTM.Should you have questions or want to explore custom VTM volume options, please contact me directly at 612-801-1007/pshuster@neuromics.com.Pete ShusterCEO and OwnerNeuromics (Source: Neuromics)
Source: Neuromics - April 15, 2020 Category: Neuroscience Tags: Coronavirus COVID-19 Storage Media COVID19 Viral Storage Media Viral Transport Media Virus Storage Media Virus Transport Media Source Type: news

Schwann Cell Data
Quality CountsThough rare, we occasionally have clients challenge the phenotype of our 21-CFR complianthuman primary cells. This challenge is usually a result of  certain markers not being expressed when they run immuno-fluorescence assays.When this happens, we too test the cells in question using the antibodies against the markers in question. We have a world class team doing immuno-fluorescence assays.Recently a customer claimed ourschwann cells were negative for GFAP and P0. Here ' re our testing results.For P0 (CH23009) we used green fluorescence +DAPI.For GFAP (RA22101) we used red fluorescence + DAPI (blue) coun...
Source: Neuromics - April 8, 2020 Category: Neuroscience Tags: GFAP Antibody Glia Markers Glial Fibrillary Acidic Protein Antibody human primary schwann cells P0 antibody PZero Antibody Schwann Cell Markers Source Type: news

We have Corona Virus Transport Media
! We are pleased to announce we now have media designed to move COVID-19 testing samples from point A to B. It ' s pricing is in line with all the many media we currently provide. If you know of any hospitals, clinics or testing facilities that would benefit we all are ears-https://www.neuromics.com/VTM #covid19 #coronavirus (Source: Neuromics)
Source: Neuromics - March 26, 2020 Category: Neuroscience Tags: Coronavirus COVID19 Source Type: news

We Are Open
Providing Cells, Media and Supplements in the time of Covid-19If you call us, we will answer the phone. If you submit an order, it will ship.Neuromics stands ready to serve you.Image: Neuromic ' s Human Pancreatic CAF-Stellate Cells in CultureFBS only $299/500 ml. We have plenty of inventory so we can continue with this pricing for the duration of the Pandemic.Stay safe. (Source: Neuromics)
Source: Neuromics - March 17, 2020 Category: Neuroscience Tags: Cancer Associated Fibroblasts FBS Fetal Bovine Serum human cancer cells Human Endothelial Cells primary human cells Source Type: news

Save Hundreds on Tet Free FBS
For Healthy and Happy CulturesCheck it out. Only $299/500 ml.USDA Origin FBS.Single use automated processing system from filtering to labeling.Questions? Contact me directly @pshuster@neuromics.com.Pete Shuster-CEO and Owner (Source: Neuromics)
Source: Neuromics - February 24, 2020 Category: Neuroscience Tags: FBS Fetal Bovine Serum Source Type: news