Rising FBS Prices Raising Your Costs?
Give us a shot Fetal Bovine Serum (FBS) is the most highly used growth factor in cell culture due to its high level of nutrients. Our FBS is produced to the highest standards in order to reduce risk and product variability and to ensure product safety and performance. Our FBS is 9CFR-tested, meeting FDA and USDA requirements. Fetal bovine serum products can also be tested to meet EMEA requirements.Note: We test each lot of FBS on our primary human cell cultures enabling us to choose lots yielding the best results...Testimonial: " We have used the FBS from Neuromics in feeding media for primary mouse astrocytes as well as f...
Source: Neuromics - January 13, 2017 Category: Neuroscience Tags: FBS Fetal Bovine Serum Source Type: news
3-D BBB Penetration Assays
Making 2017 the Year of the Tissue Like, 3-D ModelsThere is growing interest in our3-D BBB Model for testing penetration of compounds, small molecules, peptides and oligos through the BBB into our tissue like brain side. I would like to present related data:We plan on adding a pancreatic model in January so stay tuned. (Source: Neuromics)
Source: Neuromics - January 2, 2017 Category: Neuroscience Tags: 3-D Cell based Assays BBB Model Blood Brain Barrier Models Drug Discovery Source Type: news
Dopamine and Morphine Tolerance
Dopamine Identified as Key PlayerOurMu Opioid Receptor antibody is used to show that blocking dopamine decreases morphine tolerance:Wen-Ling Dai, Feng Xiong, Bing Yan, Zheng-Yu Cao, Wen-Tao Liu, Ji-Hua Liu1, Bo-Yang Yu. Blockade of neuronal dopamine D2 receptor attenuates morphine tolerance in mice spinal cord. Scientific Reports 6, Article number: 38746 (2016). doi:10.1038/srep38746.Images: (A) Double immunofluorescence staining showed that MOR (green) and D2DR (red) were co-localized in the mice spinal cord (20X magnification). Chronic morphine treatment increased the co-localization of MOR and D2DR in the spinal cord, a...
Source: Neuromics - December 28, 2016 Category: Neuroscience Tags: Dopamine MOR Antibody Morphine Mu Opioid Receptor Mu Opioid Receptor antibody Nociception Nociceptive Pain Source Type: news
Neuromics Cornerstone
Human Primary + Stem Cells and 3-D Tissue Like ModelsWe are pleased by growing demand for our" hard to find " primary cells and 3-D BBB model. These are proving to be engines for drug discovery and toxicology assays.We have have the capabilities isolate cells from healthy human donors. We then grow and characterize the cells and cryo-preserve in vials of 500,000 cells. They are now ready to culture.We are increasingly determining types of cells to add to our growing catalog by meeting the specific demand of our clients. For example, our addition of primary humanschwann cells andmicroglia happened, because they were ne...
Source: Neuromics - December 16, 2016 Category: Neuroscience Tags: 3D Human Skin Tissue Model Astrocyte-Glial-Neuron Co-cultures Astrocytes BBB Model Blood Brain Barrier Models brain microvascular endothelial cells hmicroglia Schwann Cells Source Type: news
Need Cells From Diseased Donors?
Just AskSome of our customers have expressed the need for Cells that have the phenotype of a given disease. This is especially true for researchers doing drug discovery for neuro-diseases like Alzheimer ' s and Parkinson ' s.Deriving " hard to find " cells from tissue is one of our cornerstones.If you have need for any type of human cell(s), give us a shot. I can be reached at 612-801-1007 orpshuster@neuromics.com. Thank you. Pete Shuster,CEO and Owner, Neuromics. (Source: Neuromics)
Source: Neuromics - December 13, 2016 Category: Neuroscience Tags: Astrocytes brain microvascular endothelial cells CAFs Cell based assays Cell Cultures hmicroglia tumor cells Source Type: news
Fatty Acids and IBD and Colitis
The Dangers of a High Fatty Acid DietsOur westernized high-fat diet (HFD) is associated with the development of inflammatory bowel disease (IBD), Colitis and other intestinal related diseases and cancers. Here one the root causes is identified to elevated production of pro-inflammatory cytokine-IL-1 β by macrophages. It is suspected that HFD sets off an autoimmune like cascade.This cascade is triggered by NLRP3 inflammasomes. OurApoptosis Kit-Magic Red-Real Time Cathepsin B is used to demonstrate these inflammasomes are activated via Cathepsin B Release:Shengnan Zhao, Zizhen Gong1, Jiefei Zhou1, Chunyan Tian, Yanhong Gao,...
Source: Neuromics - December 5, 2016 Category: Neuroscience Tags: 27-hydroxycholesterol Apoptosis Apoptosis Detection Colitis colon Colorectal Cancer IBD Irritable Bowel Syndrome Magic Red Apoptosis Kit Source Type: news
Need Cells?
Kick of Your Holiday Season with a 25 USD Gift CardAll cell orders this month will include a 25 USD Amazon Gift Card. This is to help celebrate the Holiday Season. Human Astroglia-Neurons Co-CulturesHere are your options.Human CellsImmortalized Human Brain Microglia CellsIsolated from healthy human brain tissuehN2 ™ Human Neurons Discovery& HT Screening KitsStable, Potent and Well CharacterizedNeuroNet Pure Human Neurons Discovery and HTS KitsPure Population of hPSC Derived NeuronsHuman Schwann Cells - NewHuman spinal nerve derived primary cellsHuman Brain Astrocytes-NewDerived from CortexCancer-Associated ...
Source: Neuromics - December 2, 2016 Category: Neuroscience Tags: adult stem cells astrocyte cultures Astrocyte-Glial-Neuron Co-cultures endothelial cells Human Mesenchymal Stem Cells Source Type: news
New Schwann Cells Now $695/500,000 Cells
Priced to Buy and Try!Schwann cells play important roles in the development, function, and regeneration of peripheral nerves. When an axon is dying, the Schwann cells surrounding it aid in its digestion, leaving an empty channel formed by successive Schwann cells, through which a new axon may then grow from a severed end.We want to make it easy for you to buy and try theseverdant cells. Also, we have a full refund or replacement should they not meet your expectations.Schwann Cells in cultureQuestions? I am available to help-Pete Shuster, CEO and Owner-612-801-1007 orpshuster@neuromics.com. (Source: Neuromics)
Source: Neuromics - November 21, 2016 Category: Neuroscience Tags: Schwann Cells Spinal cord injury repair spinal cord regeneration Source Type: news
Infection of Mesenchymal Stem Cells
UCB derived huMSCs infected with RSVsHere ' s cool customer data of ourHuman Mesenchymal Stem Cells.Figure. RSV infects and replicates in human MSCs. Human MSCs grown on coverslips, infected with 1 MOI of RSV, and immunostained at 48 or 72 hours post-infection with a monoclonal antibody to RSV tagged with FITC (green), Evan ’s blue dye (red) and DAPI (blue). Total magnification of images is 200X (inset 1000X) and scale bar is 50μm (A). RSVN transcripts detected in MSCs at 6, 12, 24 and 72 hours post infection normalized to mock (B). RSV titers (PFU/ml) isolated from the culture medium of infected and mock-infected M SCs...
Source: Neuromics - November 15, 2016 Category: Neuroscience Tags: #datawanted adult stem cells hMSCs Human Mesenchymal Stem Cells Source Type: news
Detecting Expression of CAS9
Gain Trust That Your Gene Editing is on TargetCRISPR/Cas9 is a hot genome-editing technology. However, the high frequency of off-target activity is a major issue.One way to make sure CAS9 is being properly expressed is using markers against related proteins.We are please to introduce ourCAS9 markers. We plan on adding to these in the near future.Image: Transfected Hek293 cells overexpressing the N-terminal 1-608 amino acids of S. pyogenes Cas9 . The cells were stained with MO22174 in red, and these cells also appear yellow since we counterstained with our rabbit Cas9 antibody, RA22126 to the same constr...
Source: Neuromics - November 9, 2016 Category: Neuroscience Tags: cas9 CAS9 antibodies CAS9 antibody CAS9 markers CRISP-Cas9 Staphylococcus aureus Streptococcus pyogense Source Type: news
We Want Your Data!
50 USD RewardOurCustomer Data program is progressing nicely. I am pleased to present the latest addition from Dr. Vimal Swarup, University of Utah. To qualify for the reward just email Rose Ludescher-rose@neuromics.com.Hippocampalneuron-based guidance assay. Image of micro-contact patterned chondroitin sulfate proteoglycans (pre-mixed with AlexaFluor 594) purified from astrocyte conditioned media (CM). b) Immuno-stain of the spot in (a) with anti-CSPG antibody CS56. c) Overlay of Embryonic day-18 primary rat hippocampal neurons (Cat# PC35101, Neuromics Inc.) and the underlying surface containing μC patterned CM after 48 h...
Source: Neuromics - November 4, 2016 Category: Neuroscience Tags: #datawanted E18 Primary Hippocampal Neurons Source Type: news
Co-Cultures and Tox Assays
Data End Points DifferOur clients continue to use ourcells and kits for co-culturing. The goal is to develop the mostin vivolike results possible.They find that single cell vs multi cell type co-cultures drive different data sets.At each dose, the results vary and as the dose of Bis1 increases this variation increases.We welcome your questions, input and feedback on our co-cultures. Pete Shuster, Owner,pshuster@neuromics.com or 612-801-1007. (Source: Neuromics)
Source: Neuromics - October 25, 2016 Category: Neuroscience Tags: 10-formyltetrahydrofolate dehydrogenase antibody astrocyte cultures Astrocyte-Glial-Neuron Co-cultures. cocultures. cell based assays Cytotoxicity Assays neuronal cultures Tox assays Source Type: news
" Hard to Find " Cells
You can Trust Your ResultsCells form the foundation of yourcell based assays. We work hard to provide the cells you need and, more importantly that they are healthy and happy.We are pleased to announce that we are recognized for having primary human cells that comply with federal and international regulations. This is especially important in drug discovery, because if the cells yield targets that result in future therapies this validation becomes increasingly valuable.Human BrainMicrovascular Endothelial Cells in CultureLooking for " hard to find cells " ? Check us out today.Cancer-Associated Fibroblasts (CAFs) and CellsSo...
Source: Neuromics - October 14, 2016 Category: Neuroscience Tags: Astrocytes brain microvascular endothelial cells Cancer Associated Fibroblasts Human Endothelial Cells human glia Human Microglia Human Primary Neurons Pancreatic tumor cells primary human cells Source Type: news
Canniboids and Pain Relief
Could The CB1-TRPV1 Crosstalk be a TargetOur pain marker-TRPV1-was recently referenced in an interesting study. Here researchers suggest that spatial distribution of the CB1 receptor and TRPV1 contributes to the complexity of their functional interaction.They conclude:" Therefore, in order to utilise the analgesic potential of endogenous anandamide fully in PSN, ways to interfere with the mechanisms, through which the CB1 receptor promotes anandamide-responsiveness and sensitisation of TRPV1, must be identified. Due to the co-expression of TRPV1 and the CB1 receptor in various areas of the brain, the CB1 receptor – TRPV1...
Source: Neuromics - October 6, 2016 Category: Neuroscience Tags: Cannabinoid Type-1 Receptors CB1 Receptors Medical Marijuana Transient Receptor Potential Vanilloid 1 Receptor Antibodies TRPV1 antibody Source Type: news
Your Brain Trust
Trust is hard to gain and easy to lose. My focus over the past 12 years has been to earn the trust of all our clients. This means that we do everything possible to insure our solutions work. When we come up short, we strive to resolve your issues the same day, and we have one of the easiest replacement policies in the market today. Here ' s proof. Trust and Testimonials:We useBirdEye, a 3rd party, to collect and manage feedback from our clients.★5★on BirdEye, Aug 29, 2016C. H. The order arrived quickly. The service was great!Product Name: Human Brain Microvascular Endothelial Cells, 500,000+ Cells, - (Cat# HEC02)H...
Source: Neuromics - October 4, 2016 Category: Neuroscience Tags: Human Endothelial Cells Pericytes Source Type: news
