Human and Animal Cardiomyocytes
Pure, Potent and Easy to CultureCheck out our hMSC Derived Human Cardiomyocytes-These cells are optimized to provide addition options for in-vitro testing of drug to drug candidate toxicities allowing researchers to rule out the ineffective and potentially small compounds/toxic compounds early in the process.Human Cardiomyocytes in CultureNeuromics also offersprimary rat and mouse cardiomyocyte tissue and disassociated cells. (Source: Neuromics)
Source: Neuromics - March 19, 2019 Category: Neuroscience Tags: cardiomyocytes human cardiomyocytes Mouse Cardiomyocytes Rat Cardiomyocytes Source Type: news
Neuron-Glial Markers
Featuring Neurofilament AntibodiesWe have the honor of ourNeuron-Glial Markers being referenced in manypublications. Here we wanted to feature some recent data from one of ourNeurofilament Antibodies.Fig. Merkel cells in grafted ESS are associated with neurons expression neurofilament heavy (NF-M) by eight weeks after grafting. Immunochemistry with antibodies against NF-H (red) and KRT20 (green) was used to localize neurons and Merkel cells, respectively, in ESS after grafting to mice. Nuclei were counterstained with DAPI (blue; B, D, F, H). Shown are cross sections of ESS at 4 weeks (A-B), 8 weeks (C-D), 12 weeks (E-F), a...
Source: Neuromics - March 7, 2019 Category: Neuroscience Tags: Glia Markers Neurofilament Antibody Neurofilament Markers Neuronal Markers NF-H antibody Source Type: news
Neuromics' Human Brain Pericytes Guide Axon Growth
Study Interactions Between Blood Vessels and Nerve CellsOurGFP-Labeled Human Brian Pericytes were used by Spinal Cord Injury Researchers to evaluate the efficacy of aligned microvessels to induce and control directional axon growth from neural progenitor cells in vitro and host axons in a rat spinal cord injury model. Interstitial fluid flow aligned microvessels generated from co-cultures of cerebral-derived endothelial cells and pericytes in a three-dimensional scaffold. Paul P. Partyka, Ying Jin, Julien Bouyer, Angelica DaSilva, George A. Godsey, Robert G. Nagele, Itzhak Fischer& Peter A. Galie (2019). Harnessin...
Source: Neuromics - February 27, 2019 Category: Neuroscience Tags: Axon growth axonal guidance Human Brain Pericytes Neurons Spinal cord injury Spinal cord injury repair spinal cord regeneration Source Type: news
HUVECS Guide Axon Growth
Study Interactions Between Blood Vessels and Nerve CellsOurGFP-Labeled Human Brian Pericytes were used, by researchers, to evaluate the efficacy of aligned microvessels to induce and control directional axon growth from neural progenitor cells in vitro and host axons in a rat spinal cord injury model. Interstitial fluid flow aligned microvessels generated from co-cultures of cerebral-derived endothelial cells and pericytes in a three-dimensional scaffold. Paul P. Partyka, Ying Jin, Julien Bouyer, Angelica DaSilva, George A. Godsey, Robert G. Nagele, Itzhak Fischer& Peter A. Galie (2019). Harnessing neurovascular i...
Source: Neuromics - February 27, 2019 Category: Neuroscience Tags: Axon growth axonal guidance Human Brain Pericytes Neurons Spinal cord injury Spinal cord injury repair spinal cord regeneration Source Type: news
Sorting Cancer-Associated Fibroblasts (CAFs)
Featuring Our Colorectal CAFSCAFs play a central role in the Tumor Microenvironment (TME). The TME has been identified as one of the driving factors of tumor progression and invasion. Inside this microenvironment, CAFs, a type of perpetually activated fibroblasts, have been implicated to have a strong tumor modulating effect and play a key role in areas such as drug resistance.This makes CAFs a target for cancer therapies. The challenge is the TME is heterogeneous making it a challenge to derive homogeneously relevant populations for basic research and drug discovery. This new study uses ourColorectal CAFs to identify...
Source: Neuromics - February 14, 2019 Category: Neuroscience Tags: CAFs Cancer Associated Fibroblasts CD90 colorectal CAFs Colorectal Cancer Flow cytometry PDGF Source Type: news
Neuromics Human Cells at Work
Work Great in 3-D Assays Neuromics Human Primary Cells are being used with increasing frequency in3-D Cell-Based Assays. Last month, we posted a publication referencing use of ourHuman Pericytes in a Blood-Brain Barrier Model.In this publication, our GFP-Labeled HUVECS are used in a 3-D Microfluidics Chip Model to study the impact of indoor airborne particles on human health. Yan Li, Chuanlin Hu, Pengcheng Wang, Yan Liu, Luyang Wang, Qingmeng Pi, Zhiyong Gong, Xu Yang, Michael Mak and Yang Wu (2019).Indoor nanoscale particulate matter-induced coagulation abnormality based on a human 3D microvascular model on a microfl...
Source: Neuromics - February 7, 2019 Category: Neuroscience Tags: Brain Perivascular Cells Human Brain Pericytes human umbilical cord endothelial cells huvecs Microfluidics Source Type: news
Neuromics' Islet-1 Used to Study Avian Heart Morphology
Evolution of High-Performance Hearts OurIslet-1 Antibody showed its versatility a comparative morphology of avian hearts.Figure: Sinuatrial node in Mallard (a –c), chicken HH42 (d–g), Lesser redpoll (h–j), and Jackdaw (k–m). All sections are in the transverse plane. The boxed areas in the left-hand column images indicate the areas of the images of the middle and right-hand columns. (a–c) In the Mallard, a nodal structure at the base of the right leaflet of the sinuatrial valve (black arrowhead in [a]) expressed Isl1 (b, c) and had a large coronary artery (white arrowhead in [b]). Sections 271 (cranial) to 1201 (c...
Source: Neuromics - January 28, 2019 Category: Neuroscience Tags: Comparative Morphology Avian Hearts Isl-1 islet-1 antibody Source Type: news
Markers for the Study of Diabetic Neuropathy
Widely Used and Frequently PublishedOurPain and Inflammation Research Antibodies have proven valuable for the study of neuropathic, nociceptive and inflammatory pain.This recent publication is focused on Diabetic Neuropathy. Jos é Eduardo Roa-Coria, Jorge Baruch Pineda-Farias, Paulino Barragán-Iglesias, Geovanna Nallely Quiñonez-Bastidas, Ángel Zúñiga-Romero, Juan Carlos Huerta-Cruz, Juan Gerardo Reyes-García, Francisco Javier Flores-Murrieta, Vinicio Granados-SotoView ORCID ID profile and Héctor Isaac Rocha-Gonzál ez (2019).Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyper...
Source: Neuromics - January 18, 2019 Category: Neuroscience Tags: Diabetic Neuropathy Hydrogen Sulfide Substance P TRP antibody Source Type: news
Rat Hippocampal Neurons
Used to Study Apoptosis Induced by Brain InsultsAlthough ourprimary human cells are increasingly being used in drug discovery and toxicology assays versusanimal cells, we are always pleased to see the success of the latter in sophisticated studies.This publication references use of oure18 rat hippocampal neurons. These cells continue to beeasy to culture, pure and potent. Chiara Porro, Antonia Cianciulli, Teresa Trotta, Dario Domenico Lofrumento, Rosa Calvello and Maria Antonietta Panaro. (2019).Formyl-methionyl-leucyl-phenylalanine Induces Apoptosis in Murine Neurons: Evidence for NO-Dependent Caspase-9 Activation. Biolog...
Source: Neuromics - January 9, 2019 Category: Neuroscience Tags: cell culturing protocol E18 Primary Hippocampal Neurons fMLP Formyl-methionyl-leucyl phenylalanine primary Neuronal Cells Source Type: news
Human Primary Cells Trifecta
Tri-culture of Neuromics ' Human Primary Cells in 3-D BBB Model I mentioned in an earlier post that we take Researchers questioning the validity of ourHuman Primary Cells very seriously. We follow up with our clients to make sure our cells are working as expected. If they are not 100% happy, we offer a free replacement or full refund....So it is encouraging to see Researchers using ourHuman Pericytes, Brain Microvascular Endothelial Cells (HBMES) andAstrocytes to build a static 3-D Blood-Brain Barrier Model.Ece Bayir, M. Mert Celtikoglu, Aylin Sendemira.The use of bacterial cellulose as a basement membrane improv...
Source: Neuromics - January 1, 2019 Category: Neuroscience Tags: Astrocytes BBB Model Blood Brain Barrier Models –brain barrier penetration brain microvascular endothelial cells Brain Perivascular Cells HBMECs Human Brain Pericytes Source Type: news
Primary Human Brain Pericytes
Pure and PotentThe authors of a chapter on pericytes published in SpringerLink referred to ourhuman primary pericytes as " pericyte-like " , but chose not to characterize them because of the " exorbitant cost " . Dore-Duffy P., Esen N. (2018) The Microvascular Pericyte: Approaches to Isolation, Characterization, and Cultivation. In: Birbrair A. (eds) Pericyte Biology - Novel Concepts. Advances in Experimental Medicine and Biology, vol 1109. Springer, ChamGiven that these pericytes are also part of our hot selling3-D Human BBB Model, we are in the process of challenging these claims. We will always take inaccurate clai...
Source: Neuromics - December 27, 2018 Category: Neuroscience Tags: 3-D Blood-Brain Barrier Model Actin Antibody BBB Model Blood Brain Barrier Models Brain Perivascular Cells Desmin Antibody Human Brain Pericytes Immunofluorescence Source Type: news
Neuromics FBS at 259 USD/500 ml.
Only 2 Weeks LeftWe wanted to get ourFBS in the hands of more cell culturing experts. Our low pricing has accelerated purchasing of this culture supplement.More importantly, we are pleased with the positive feedback. Here are some recentreviews.Linda S.on BirdEye ★★★★★9 days agoMy experience with Neuromics was very positive. I asked for a sample of FBS and after to use the FBS I received. Peter T.on BirdEye ★★★★★month agoI purchased FBS from Neuromics. It was shipped to Canada without any problems. It arrived safely and still frozen. Cells grow well in the product. Customer ser...
Source: Neuromics - December 15, 2018 Category: Neuroscience Tags: FBS Fetal Bovine Serum Source Type: news
Pain Receptors and Diabetic Neuropathy
We Got the MarkersOurMarkers for Pain Research are widely used and frequently published. They are often referenced in publications on Diabetic nerve pain.Here are some of my past blog postings:Cytokines and Neuropathic PainEpidermal Nerve Fibers in Neuropathic Pain ModelPain Research and Gene Expression AnalysisHere ' s a model of the actual nerve receptors behind both intractable pain and loss of sensation.A: Simplified model of nociception under normal conditions. Free nerve endings transduce a painful stimulus into a neural signal, which propagates to DRG centrally and eventually synapses on a nociceptive neuron within ...
Source: Neuromics - November 27, 2018 Category: Neuroscience Tags: Diabetes Research Diabetic Neuropathy Diabetic retinopathy GABA NMDAR P2X3 TRPV1 Source Type: news
Primary Human Schwann Cells
Research ReadyOurSchwann Cells have proven " rock solid " in the hands of our users.Image: Human Primary Schwann Cells in CultureHuman Schwann Cells (HSwC) are isolated from the human spinal nerve. HSwC are cryopreserved at passage one and delivered frozen. Each vial contains>5 x 10^5 cells in 1 ml volume. HSwC are characterized by immunofluorescence with antibodies specific to S100, GFAP, and CD90 (Source: Neuromics)
Source: Neuromics - November 17, 2018 Category: Neuroscience Tags: human primary schwann cells Schwann Cell Markers Source Type: news
Cardiomyocytes
Pure, Potent and Research ReadyWe are recognized for our growing catalog of human primary and stem cells.These include hMSC DerivedCardiomyocytes.Human Cardiomyocytes stained with Cardiac Tryponin T (green) and counter stained with DAPI (blue).These cells are optimized to provide additional options for in-vitro testing of drug to drug candidate toxicities allowing researchers to rule out the ineffective and potentially toxic small molecules/compounds early in the process. (Source: Neuromics)
Source: Neuromics - October 27, 2018 Category: Neuroscience Tags: cardiomyocyte based assays cardiomyocytes human cardiomyocytes Source Type: news
