Can You Take Creatine If You Have High Blood Pressure?
Conclusion
We’ve journeyed through the multifaceted world of creatine, from its role in boosting athletic performance to its potential therapeutic uses. We’ve also delved into the crucial relationship between creatine and high blood pressure, highlighting the need for caution.
The key takeaway? If you have high blood pressure, consult a healthcare provider before taking creatine. It’s not just a supplement; it’s a substance that interacts with various bodily functions and can have significant implications for your health.
So, before you consider adding creatine to your routine, make t...
Source: The EMT Spot - August 29, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Webinar for NIH MOSAIC Program Applicants
Are you preparing a grant application for the NIH Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) K99/R00 or UE5 programs? If so, please join our webinar to learn more about the programs and application components and to ask questions:
Tuesday, September 12, 1:00-3:00 p.m. ET
Zoom meeting link
Join by phone
Meeting ID: 160 151 7840
Passcode: 249272
MOSAIC is an NIH-wide initiative to enhance faculty diversity in the biomedical research workforce. It has two components: a postdoctoral career transition award (K99/R00) and a cohort-based mentoring and career...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - August 28, 2023 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Meetings/Events Training/Fellowships/Career Development Biomedical Graduate Education Biomedical Research Enterprise MOSAIC Postdoctoral Webinars Source Type: blogs
Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan.
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Trials of Xenotransplantation of Pig Organs into Humans Continue
https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/
Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants i...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Trials of Xenotransplantation of Pig Organs into Humans Continue
Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants into terminally ill volunteers and brain dead individuals who donated their bodies to science. To learn by doing is really the only practical way by which the presently unknown problems are discovered. This trial of kidney transplantation ran for longer than prior efforts, and is a step on the path to producing a ready supply of non-human organs for transplantation, a technology that will compete with efforts to grow new organs on demands.
Su...
Source: Fight Aging! - August 24, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Evidence review: Physical exercise helps boost attention, cognitive flexibility and inhibitory control in children and adolescents with ADHD
Conclusions based on a single study –no matter how strong the study design and execution may be– are necessarily limited, however. This has led researchers to combine results from multiple studies using a statistical technique called meta-analysis so that more robust and reliable estimates of a treatment’s impact can be determined.
Meta-analyses also have limitations, however. Decisions made about which studies to include vs. exclude, how to adjust for potential biases in individual studies, etc., can lead different meta-analyses of the same issue to reach somewhat different conclusions, even when the studies examine...
Source: SharpBrains - August 23, 2023 Category: Neuroscience Authors: Dr. David Rabiner Tags: Attention & ADD/ADHD Brain/ Mental Health Education & Lifelong Learning ADHD-symptoms cognitive-abilities cognitive-function executive functioning Physical-activity Source Type: blogs
Exploring Psychedelic Microdosing
Recently I’ve taken an interest in microdosing, specifically with magic mushrooms. I began learning about it a few months ago and then learned even more at the Psychedelic Science conference in June. I’ve also had some recent conversations with people I know who’ve been microdosing, all of them reporting positive long-term effects. Most use mushrooms for microdosing, although one prefers microdosing with LSD.
The point of microdosing is to take a very small amount of a psychedelic substance in order to access some neurological gains without any obvious psychedelic effects or impairments. Those gains can be both sh...
Source: Steve Pavlina's Personal Development Blog - August 21, 2023 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Creating Reality Emotions Health Lifestyle Productivity Source Type: blogs
Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Dancing around the hexaflex: Using ACT in practice 1
Acceptance and commitment therapy (ACT) can be slippery to describe. It’s an approach that doesn’t aim to change thought content, but instead to help us shift the way we relate to what our mind tells us. It’s also an approach focused on workability: pragmatic and context-specific analysis of how well a strategy is working to achieve being able to do what matters. Over the next few posts I want to give some examples of how non-psychologists (remember ACT is open for anyone to use it!) can use ACT in session.
Mindfulness – messing about with attention
Thanks to Kevin Vowles, I’m adopting t...
Source: HealthSkills Weblog - August 20, 2023 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: ACT - Acceptance & Commitment Therapy Back pain Chronic pain Clinical reasoning Coping strategies Low back pain Occupational therapy Physiotherapy Psychology Research Resilience Resilience/Health Science in practice mindful movem Source Type: blogs
Progress Towards Therapies for Transthyretin Amyloidosis
Transthyretin is one of the few proteins in the body that can misfold in a way that encourages other copies of the protein to also misfold, forming solid aggregates called amyloid that disrupt tissue structure and function. The resulting condition, transthyretin amyloidosis, clogs up cardiac tissue and thereby contributes to a fraction of all heart failure cases. It is thought to be a major cause of mortality in supercentenarians. Approved therapies targeting a more aggressive form of the condition resulting from a mutated transthyretin gene will not be useful against the much more common version of the condition, as they ...
Source: Fight Aging! - August 18, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Hopes and Questions raised by Alzheimer ’s drug Leqembi (lecanemab)
The FDA has approved Leqembi, the first disease-modifying treatment for early-stage Alzheimer’s and a precursor condition, mild cognitive impairment. Medicare has said it will pay for the therapy. Medical centers across the country are scrambling to finalize policies and procedures for providing the medication to patients, possibly by summer’s end or early autumn.
It’s a fraught moment, with hope running high for families and other promising therapies such as donanemab on the horizon. Still, medical providers are cautious. “This is an important first step in developing treatments for complex neurodegenerative disea...
Source: SharpBrains - August 17, 2023 Category: Neuroscience Authors: Judith Graham at Kaiser Health News Tags: Brain/ Mental Health cognition early-stage Alzheimer’s Eisai FDA lecanemab Leqembi Medicare mild-cognitive-impairment Source Type: blogs
Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health."
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Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis?
https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/
Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't ...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fwd: You ’re a panelist for Evalu8 - Clinical Customer Conference Day 5
****************************************** Kevin S. McGrew, PhD Educational& School Psychologist Director Institute for Applied Psychometrics (IAP)https://www.themindhub.com ******************************************---------- Forwarded message ----------From: Neha Anand<customercare@gotowebinar.com>Date: Aug 1, 2023 at 8:39 AM -0500To: iqmcgrew@gmail.comCc: neha.anand@riversideinsights.comSubject: You ' re a panelist for Evalu8 - Clinical Customer Conference Day 5Evalu8 - Clinical Customer Conference Day 5Fri, Aug 11, 2023 11:00 AM - 1:00 PM CDTDear Kevin McGrew,Neha Anand (neha.anand@riversideinsights.com) has ...
Source: Intelligent Insights on Intelligence Theories and Tests (aka IQ's Corner) - August 10, 2023 Category: Neuroscience Source Type: blogs
