8 ‑week Mindfulness-Based Stress Reduction (MBSR) course found to be as effective as Lexapro (escitalopram) to treat adults with anxiety disorders, and with far fewer side effects
In this study, 276 patients with an anxiety disorder were randomly assigned to either an eight-week course of MBSR or a well-known anti-anxiety drug, Lexapro (with ongoing monitoring). The MBSR course, developed by Jon Kabat-Zinn, involved introducing people to a variety of meditation practices (like mindful breathing, body scans, walking meditation, and loving-kindness meditation) and having them meditate daily at home to improve their skills. Overall, the training is designed to help people learn how to pay attention to the present moment and accept whatever sensations, thoughts, and feelings arise without judgment. Duri...
Source: SharpBrains - April 19, 2023 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning anxiety anxiety disorder body scans cognitive-behavioral-therapy Lexapro mbsr medication meditation mindful breathing Mindfulness-Based-Stress-Reduction psychiatric disorder psyc Source Type: blogs

When life happens … .
Most of my writing comes from mulling over recent events as played out either in social media or research findings. Today’s post is a little different. It’s no secret that I live with persistent pain, fibromyalgia to be exact. I’ve found that being open about my diagnosis, and that all the strategies I advise to others are also strategies I employ, and that none of them are ‘the secret.’ I posted recently about a struggle I have dealing with reviewer’s comments on papers I submit for publication. Now peer review is a thing, I think it’s a good thing though somewhat exploitative ...
Source: HealthSkills Weblog - April 16, 2023 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Uncategorized Source Type: blogs

Fight Aging! Newsletter, April 17th 2023
In conclusion, oral NR altered the gut microbiota in rats and mice, but not in humans. In addition, NR attenuated body fat mass gain in rats, and increased fat and energy absorption in the HFD context. Glycine Supplementation as a Methionine Restriction Mimetic https://www.fightaging.org/archives/2023/04/glycine-supplementation-as-a-methionine-restriction-mimetic/ Supplementation with the non-essential amino acid glycine has been shown to modestly slow aging in short-lived laboratory species. In today's open access review paper, researchers note glycine supplementation as essentially a calorie restricti...
Source: Fight Aging! - April 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Uncertainty Effect with Michelle Lazarus | TAPP 135
Dr. Michelle Lazarus, author of the new book,The Uncertainty Effect: How to Survive and Thrive through the Unexpected, joins host Kevin Patton for a lively discussion of ofuncertainty in science, medicine, and academia.00:00 | Introduction00:50 | Dr. Michelle Lazarus04:57 | Sponsored by AAA05:31 | Why Is Uncertainty Important?17:05 | Sponsored by HAPI17:49 | The Uncertainty of Teaching A&P27:07 | Sponsored by HAPS28:05 | Uncertainty and Inclusion36:38 | Uncertainty and Risk38:48 | Book: The Uncertainty Effect39:51 | Staying Connected ★ If you cannot see or activate the audio player, go to:the...
Source: The A and P Professor - April 12, 2023 Category: Physiology Authors: Kevin Patton Source Type: blogs

Pilot program by IU and Davos Alzheimer ’s Collaborative to test AI-powered cognitive screening at scale
How AI, Digital Screening Tools Can Help Flag Early Cognitive Decline (Health IT Analytics): Early diagnosis of Alzheimer’s and other dementias remains at the forefront of efforts to minimize the impact of these neurodegenerative diseases. But challenges such as increased life expectancy and the risks of aging, along with complexities in diagnosis and treatment resulting from mixed brain pathologies, make early detection difficult … A new pilot program at Indiana University School of Medicine and Indiana University Health, in collaboration with the Davos Alzheimer’s Collaborative (DAC), seeks to tackle these issues u...
Source: SharpBrains - April 11, 2023 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation aging artificial intelligence cognitive decline cognitive evaluation Cognitive-impairment Davos Alzheimer’s Collaborative digital screening early diagnosis of Alzheimer's Linus Health Li Source Type: blogs

Immunotherapies Targeting Amyloid- β May Produce Brain Shrinkage
Immunotherapies offer great potential, but are not without side-effects as presently implemented. This is well demonstrated in the cancer field, where a chance of severe short-term, or even lasting immune-related issues is a risk that patients are willing to take given the alternatives on the table. Here, researchers suggest that the immunotherapies tested against Alzheimer's disease in clinical trials are producing an accelerated shrinkage of brain tissue, perhaps because of raised inflammation. In recent years, these immunotherapies have succeeded in clearing extracellular amyloid-β, but have not improved patient outcom...
Source: Fight Aging! - April 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, April 10th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 9, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How Tech Can Optimize Protocol-Driven Care For Children With Medical Complexity
The following is a guest article by Tammi Jantzen, Co-Founder & CFO at Astarte Medical Medical advances have led to improved survival for many previously life-threatening conditions of childhood, such as prematurity, congenital anomalies (like congenital heart defects), and congenital or acquired brain injury (like cerebral palsy). Technological advances such as ventilator support, feeding tubes and transplantation have successfully prolonged the lives of children with lung, gut, and other organ failure. This epidemiological shift has created a growing population of children with medical complexity (CMC)—children...
Source: EMR and HIPAA - April 7, 2023 Category: Information Technology Authors: Guest Author Tags: Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Astarte Medical Children with Medical Complexity Chronic Health Condition CMC Congenital Diseases Digital Tools EMR Inappropriate Care Ne Source Type: blogs

Specific reading disabilities.
https://psycnet.apa.org/record/2023-47082-005Reading represents the most common academic domain in which children and young adults experience difficulties in school. Specific reading disabilities (SRDs) are neurodevelopmental disorders that emerge early in development and persist into adulthood. They are characterized by protracted difficulties reading and spelling words with accuracy, reading words and text with fluency, and constructing meaning from written text. This chapter reviews research on SRDs, a disorder characterized by protracted difficulties in reading. It begins with a review of research related to the interr...
Source: Intelligent Insights on Intelligence Theories and Tests (aka IQ's Corner) - April 4, 2023 Category: Neuroscience Source Type: blogs

Model Specification Searches in Structural Equation Modeling Using Bee Swarm Optimization - Ulrich Schroeders, Florian Scharf, Gabriel Olaru, 2023
 Model Specification Searches in Structural Equation Modeling Using Bee Swarm Optimization - Ulrich Schroeders, Florian Scharf, Gabriel Olaru, 2023  https://journals.sagepub.com/doi/10.1177/00131644231160552Metaheuristics are optimization algorithms that efficiently solve a variety of complex combinatorial problems. In psychological research, metaheuristics have been applied in short-scale construction and model specification search. In the present study, we propose a bee swarm optimization (BSO) algorithm to explore the structure underlying a psychological measurement instrument. The algorithm assigns items to a...
Source: Intelligent Insights on Intelligence Theories and Tests (aka IQ's Corner) - April 4, 2023 Category: Neuroscience Source Type: blogs

Harnessing mindfulness and virtual reality simulations to maximize sports performance
Athletes at the very highest level of their sport face the challenge of performing consistently under pressure amid many potential distractions, including performance anxiety, crowd behaviour, their own and others’ expectations, and the responses of their opponents. The performance of players in the 2023 Australian Open, for example, demonstrated the psychological factors needed to succeed at elite-level tennis. It had plenty of exciting moments that are the hallmarks of a great tournament. Andy Murray made an astonishing comeback from two sets down against Thanasi Kokkinakis, following his long recovery after major inju...
Source: SharpBrains - April 3, 2023 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Peak Performance high performance meditation mindfulness Mindfulness-Training resilience sport psychologists sport psychology virtual-reality Source Type: blogs

Good news about hypoglycemia awareness
Welcome to episode 3 of BDI Briefs! Our aim with BDI Briefs is to take a brief look at important issues about the emotional side of diabetes.In this short discussion, Scott, Bill, and Susan discuss some good news recently published about the fear of hypoglycemia. I also encourage you to look at more research from the Behavioral Diabetes Institute. Enjoy! And please let us know what you think and what you’d like to hear more about from BDI.And remember to subscribe to BDI’s YouTube channel!   Detailed show notes and transcript ...
Source: Scott's Diabetes Blog - March 30, 2023 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs

Pear Therapeutics loses 97% of its market capitalization since 2021, explores strategic alternatives
Source: Google Finance Pear Therapeutics exploring sale, other ‘strategic alternatives’ (MobiHealth News): Prescription digital therapeutics company Pear Therapeutics is exploring “strategic alternatives,” including a possible company sale, merger or acquisition. In a press release, the company said it hired a financial advisor to look into actions that could “maximize shareholder value.” That includes a potential sale, M&A, divestiture of assets, licensing or other strategic transactions. It may also seek additional financing. The company hit the public markets in late 2021 through a merger with a special ...
Source: SharpBrains - March 29, 2023 Category: Neuroscience Authors: SharpBrains Tags: Technology & Innovation MTS Health Partners Pear Therapeutics prescription digital therapeutics special purpose acquisition company Source Type: blogs

TDP-43 Aggregation Leads to Loss of Stathmin-2 Expression and Inability of Neurons to Regenerate Axons
Researchers here delve into the mechanisms by which TDP-43 aggregation contributes to the symptoms of neurodegenerative conditions in which it is involved. It disrupts expression of another gene, stathmin-2, degrading the ability of neurons to maintain axonal connections. This is a feature of ALS, the condition most readily associated with TDP-43 aggregation. The research here points to an approach to therapy: not restoration of appropriate TDP-43 behavior, but rather finding a way to force correct expression of stathmin-2. It remains the case that TDP-43 aggregation may well cause other problems unrelated to this mechanis...
Source: Fight Aging! - March 28, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs