CBG Oil ’ s Impact on Blood Pressure: Risks, Benefits, and Future Potential
Uncover the fascinating findings of a recent study on CBG oil and its effects on blood pressure, the potential dangers for those with normal levels, and the promising avenues for further research and therapeutic applications in the realm of cannabinoids. Quick Summary CBG oil, a lesser-known cannabinoid, has been found to significantly decrease blood pressure in healthy mice, according to a study conducted at the Pennsylvania State University College of Medicine. While CBG oil has potential as a treatment for high blood pressure, it could be dangerous for individuals with normal blood pressure levels due to the r...
Source: The EMT Spot - May 7, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Fight Aging! Newsletter, May 8th 2023
In conclusion, NAT mitigated age-associated cerebral injury in mice through gut-brain axis. The findings provide novel evidence for the effect of NAT on anti-aging, and highlight the potential application of NAT as an effective intervention against age-related diseases. Retinal Cell Reprogramming Restores Vision in Non-Human Primate Study https://www.fightaging.org/archives/2023/05/retinal-cell-reprogramming-restores-vision-in-non-human-primate-study/ Early applications of in vivo cellular reprogramming to medicine are cautiously focused on retinal regeneration. The eye is as close to an isolated system...
Source: Fight Aging! - May 7, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Science Snippet: The Power of Proteins
Some might think that protein is only important for weightlifters. In truth, all life relies on the activity of protein molecules. A single human cell contains thousands of different proteins with diverse roles, including: Actin proteins in a cell’s cytoskeleton. Credit: Xiaowei Zhuang, HHMI, Harvard University, and Nature Publishing Group. Providing structure. Proteins such as actin make up the three-dimensional cytoskeleton that gives cells structure and determines their shapes. Aiding chemical reactions. Many proteins are biological catalysts called enzymes that speed up the rate of chemical reactions by redu...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 3, 2023 Category: Research Authors: Chrissa Chverchko Tags: Cells Molecular Structures Cellular Processes Medicines Proteins Science Snippet Source Type: blogs

Study shows the power of electroencephalography and machine learning to help predict response to psychotherapy (or lack thereof) in patients with PTSD
This study investigates whether individual patient-level resting-state EEG connectivity can predict psychotherapy outcomes in PTSD. We developed a treatment-predictive EEG signature using machine learning applied to high-density resting-state EEG collected from military veterans with PTSD. The predictive signature was dominated by theta frequency EEG connectivity differences and was able to generalize across two types of psychotherapy—prolonged exposure and cognitive processing therapy. Our results also advance a biological definition of a PTSD patient subgroup who is resistant to psychotherapy, which is currently the mo...
Source: SharpBrains - May 2, 2023 Category: Neuroscience Authors: Dr. Amit Etkin at Alto Neuroscience Tags: Brain/ Mental Health Technology & Innovation Alto Neuroscience cognitive processing therapy digital biomarker electroencephalography posttraumatic stress disorder precision psychiatry prolonged exposure Psychotherapy PTSD Source Type: blogs

Digital Self-Neuromodulation Therapy for PTSD: Interview with Oded Kraft, CEO of GrayMatters Health
GrayMatters Health, a medtech company based in Israel, has developed Prism for PTSD, a self-neuromodulation therapy. The company has identified what they describe as brain-mechanism-specific biomarkers for certain mental disorders. These involve combining fMRI and EEG data. The Prism for PTSD system targets a specific biomarker called amygdala-derived-EFP, which is involved in the fight or flight response, and which can frequently be triggered in those with PTSD. The new technique that GrayMatters Health developed involves applying an EEG cap to a patient’s head, and then placing them in front of a screen. An animatio...
Source: Medgadget - May 2, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Neurology Psychiatry GraymattersH PTSD Source Type: blogs

It ’s Private: Innovative Techniques Begin to Address Clinicians’ Mental Health
The following is a guest article by William J. Hayes, M.D., M.B.A., and Chief Medical Officer at CPSI New collaboration between mobile app developer, EHR vendor and health systems decreases clinician stress The perennial challenge of clinical burnout has reached an inflection point. Fueled by PTSD from COVID-19, burnout is largely based on the modern human experience of constantly consuming stimuli (much of which is negative) while also being pushed to achieve higher levels of productivity and efficiency. Those that have been impacted the greatest of any group have been our physicians, nurses, therapists, and other healthc...
Source: EMR and HIPAA - May 2, 2023 Category: Information Technology Authors: Guest Author Tags: Ambulatory C-Suite Leadership Clinical EMR-EHR Health IT Company Healthcare IT Hospital - Health System LTPAC Brain Drain COVID-19 CPSI Dr. Gloria Mark Dr. Izzy Justice EQ Health Healthcare Burnout mental health Mental Heal Source Type: blogs

Reviewing Present Biomarkers of Aging
Today's open access paper, with more than 120 contributing authors, is a tour of the broad topic of biomarkers of aging, an attempt to say at least something about every aspect of cellular biochemistry and functional capacity that is either used or proposed to be used to measure biological age, from grip strength to epigenetic clocks. Biological age is in one sense an aspirational concept, a way to measure the progression of aging that will accurately reflect mortality and disease risk. In another sense, biological age is self-evidently real. Different people age at different rates, and exhibit very different risk levels f...
Source: Fight Aging! - May 1, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

ChatGPT May Not be Ready to Revolutionize the Healthcare Industry Quite Yet, But There ’s Promise for the Future
The following is a guest article by Heather Lane, Senior Architect of Data Science at athenahealth   Artificial intelligence (AI) and machine learning (ML) have transformed numerous industries in recent years, and healthcare is no exception. AI-powered chatbots, such as ChatGPT, have emerged as tools that have the potential to drastically transform healthcare and the delivery of personalized care. However, while these chatbots hold promise for revolutionizing healthcare, there are several reasons why these technologies require more time to prepare for widespread adoption. While there is no denying that ChatGPT is appealin...
Source: EMR and HIPAA - May 1, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Ambulatory C-Suite Leadership Clinical EMR-EHR Health IT Company Healthcare IT AI-Assisted Chat Artificial Intelligence athenahealth Chart Summarization ChatGPT False Negatives Healthcare AI Healthcare AI Bi Source Type: blogs

“ … someone needs to find the cause of my pain, then fix it. ” What to do with sticky beliefs
I think most clinicians, and certainly a lot of people living with pain, want to know ‘what’s going on’ – with the hope that, once identified, ‘something’ can be done. Tricky stuff to navigate both as a person living with pain, and as a clinician – because for so many chronic pains, a diagnosis does very little. Having a label has some benefits, for sure: it acts as a short-hand when talking about what’s going on with others; it can validate that the mysterious problems a person has been having are ‘real’ (though I could say more about that!); it can help peop...
Source: HealthSkills Weblog - April 30, 2023 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: ACT - Acceptance & Commitment Therapy Chronic pain Clinical reasoning Coping strategies Occupational therapy Physiotherapy Professional topics Psychology Research Science in practice biopsychosocial pain management Therapeutic appr Source Type: blogs

On the 7 Habits of Highly Stress-Resilient Minds, cognitive screenings, anti-amyloid drugs, and more
Welcome to a new edition of SharpBrains e‑newsletter, this time covering the latest developments in stress research, meditation, virtual reality, anti-amyloid drugs, cognitive screenings, and more. #1. The 7 Habits of Highly Stress-Resilient Minds “Anything worth doing will have aspects of stress woven through: challenge, discomfort, risk. We can’t change that. But what we can change is our response” – Elissa Epel, Director of the Aging, Metabolism, and Emotions Center at UCSF #2. Harnessing mindfulness and virtual reality simulations to maximize sports performance Good tips and tools to “simulate or repli...
Source: SharpBrains - April 27, 2023 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Education & Lifelong Learning SharpBrains Monthly eNewsletter anti-amyloid drugs cognitive-screenings digital medicine lecanemab Leqembi Linus Health Core Cognitive Evaluation meditation Mindfulness-Based-Stress-Re Source Type: blogs

Worms Aren ’ t So Dumb
BY KIM BELLARD Chances are, you’ve read about AI lately.  Maybe you’ve actually even tried DALL-E or ChatGPT, maybe even GPT-4.  Perhaps you can use the term Large Language Model (LLM) with some degree of confidence.  But chances are also good that you haven’t heard of “liquid neural networks,” and don’t get the worm reference above.    That’s the thing about artificial intelligence: it’s evolving faster than we are. Whatever you think you know is already probably out-of-date. Liquid neural networks were first introduced in 2020.  The authors wrote: “We introduce a new class of time-continu...
Source: The Health Care Blog - April 26, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech Kim Bellard Liquid Neural Networks Worms Source Type: blogs

Processing Speed is Related to the General Psychopathology Factor in Youth | SpringerLink
 Processing Speed is Related to the General Psychopathology Factor in Youth | SpringerLink  https://link.springer.com/article/10.1007/s10802-023-01049-wThe relationship between the p factor and cognition in youth has largely focused on general cognition (IQ) and executive functions (EF). Another cognitive construct, processing speed (PS), is dissociable from IQ and EF, but has received less research attention despite being related to many different mental health symptoms. The present sample included 795 youth, ages 11 –16 from the Colorado Learning Disabilities Research Center (CLDRC) sample. Confirma...
Source: Intelligent Insights on Intelligence Theories and Tests (aka IQ's Corner) - April 25, 2023 Category: Neuroscience Source Type: blogs

Fight Aging! Newsletter, April 24th 2023
In this study, researchers show that mice lacking a functional ATF4 gene show little to no loss of grip strength and treadmill performance into late life; it is quite an impressive effect size. Assessments of muscle biochemistry do show age-related declines, but to a lesser degree than the controls. How ATF4 knockout functions to produce this outcome is an interesting question. The researchers point out a range of possible downstream and upstream targets that have been implicated in the regulation of muscle growth, but it will clearly require further work to identify the important mechanisms involved. Aging slowly...
Source: Fight Aging! - April 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

8 ‑week Mindfulness-Based Stress Reduction (MBSR) course found to be as effective as Lexapro (escitalopram) to treat adults with anxiety disorders, and with far fewer side effects
In this study, 276 patients with an anxiety disorder were randomly assigned to either an eight-week course of MBSR or a well-known anti-anxiety drug, Lexapro (with ongoing monitoring). The MBSR course, developed by Jon Kabat-Zinn, involved introducing people to a variety of meditation practices (like mindful breathing, body scans, walking meditation, and loving-kindness meditation) and having them meditate daily at home to improve their skills. Overall, the training is designed to help people learn how to pay attention to the present moment and accept whatever sensations, thoughts, and feelings arise without judgment. Duri...
Source: SharpBrains - April 19, 2023 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning anxiety anxiety disorder body scans cognitive-behavioral-therapy Lexapro mbsr medication meditation mindful breathing Mindfulness-Based-Stress-Reduction psychiatric disorder psyc Source Type: blogs

When life happens … .
Most of my writing comes from mulling over recent events as played out either in social media or research findings. Today’s post is a little different. It’s no secret that I live with persistent pain, fibromyalgia to be exact. I’ve found that being open about my diagnosis, and that all the strategies I advise to others are also strategies I employ, and that none of them are ‘the secret.’ I posted recently about a struggle I have dealing with reviewer’s comments on papers I submit for publication. Now peer review is a thing, I think it’s a good thing though somewhat exploitative ...
Source: HealthSkills Weblog - April 16, 2023 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Uncategorized Source Type: blogs